| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kara L Cummings, Rick L Tarleto. Inducible nitric oxide synthase is not essential for control of Trypanosoma cruzi infection in mice. Infection and immunity. vol 72. issue 7. 2004-08-06. PMID:15213153. |
increased transcription of nos1 or nos3 is not found in inos-knockout (ko) mice, indicating that the absence of nitric oxide production through inos is not compensated for by increased production of other nos isoforms. |
2004-08-06 |
2023-08-12 |
mouse |
| Takahiro Shinkai, Osamu Ohmori, Chima Matsumoto, Hiroko Hori, James L Kennedy, Jun Nakamur. Genetic association analysis of neuronal nitric oxide synthase gene polymorphism with tardive dyskinesia. Neuromolecular medicine. vol 5. issue 2. 2004-07-20. PMID:15075442. |
in the present study, the relationship between td and a polymorphism of the neuronal nitric oxide synthase (nos1) gene whose reaction product, nitric oxide (no), is involved in oxidative stress was studied in 171 japanese patients with schizophrenia, including 41 patients meeting td criteria. |
2004-07-20 |
2023-08-12 |
human |
| K Renaudin, M G Denis, G Karam, G Vallette, F Buzelin, C L Laboisse, A Jarr. Loss of NOS1 expression in high-grade renal cell carcinoma associated with a shift of NO signalling. British journal of cancer. vol 90. issue 12. 2004-07-13. PMID:15150612. |
nos1 expression and activity were found to be downregulated, correlating with the tumour grade, as shown by immunohistochemistry, quantitative rt-pcr analysis, and histochemical detection of the nadph-diaphorase activity of nitric oxide synthases (nos). |
2004-07-13 |
2023-08-12 |
human |
| Chenchen Shao, Yoichi Suzuki, Fumiaki Kamada, Kiyoshi Kanno, Mayumi Tamari, Koichi Hasegawa, Yoko Aoki, Shigeo Kure, Xue Yang, Hiroko Endo, Reiko Takayanagi, Chifuyu Nakazawa, Toshio Morikawa, Miki Morikawa, Shigeaki Miyabayashi, Yasushi Chiba, Minoru Karahashi, Seichi Saito, Gen Tamura, Taro Shirakawa, Yoichi Matsubar. Linkage and association of childhood asthma with the chromosome 12 genes. Journal of human genetics. vol 49. issue 3. 2004-05-20. PMID:14767694. |
chromosome 12 genes that showed association with the disease in at least one report include: the signal transducer and activator of transcription 6 gene ( stat6), the nitrogen oxide synthetase 1 gene ( nos1), the interferon gamma gene ( ifng), and the activation-induced cytidine deaminase gene ( aicda). |
2004-05-20 |
2023-08-12 |
Not clear |
| J Texereau, S Marullo, D Hubert, J Coste, D J Dusser, J Dall'Ava-Santucci, A T Dinh-Xua. Nitric oxide synthase 1 as a potential modifier gene of decline in lung function in patients with cystic fibrosis. Thorax. vol 59. issue 2. 2004-03-22. PMID:14760158. |
the nitric oxide synthase 1 (nos1) gene is a candidate for this role because exhaled nitric oxide (no) is reduced in patients with cf and nos1 activity contributes to transepithelial ionic transport, immune defence, and non-specific inflammation of the airways. |
2004-03-22 |
2023-08-12 |
Not clear |
| Anne Jarry, Karine Renaudin, Marc G Denis, Myriam Robard, Bénédicte Buffin-Meyer, Georges Karam, Françoise Buzelin, Hervé Paris, Christian L Laboisse, Geneviève Vallett. Expression of NOS1 and soluble guanylyl cyclase by human kidney epithelial cells: morphological evidence for an autocrine/paracrine action of nitric oxide. Kidney international. vol 64. issue 1. 2004-03-19. PMID:12787407. |
expression of nos1 and soluble guanylyl cyclase by human kidney epithelial cells: morphological evidence for an autocrine/paracrine action of nitric oxide. |
2004-03-19 |
2023-08-12 |
human |
| Anne Jarry, Karine Renaudin, Marc G Denis, Myriam Robard, Bénédicte Buffin-Meyer, Georges Karam, Françoise Buzelin, Hervé Paris, Christian L Laboisse, Geneviève Vallett. Expression of NOS1 and soluble guanylyl cyclase by human kidney epithelial cells: morphological evidence for an autocrine/paracrine action of nitric oxide. Kidney international. vol 64. issue 1. 2004-03-19. PMID:12787407. |
the aim of the present study was to characterize and localize in situ the nitric oxide synthase (nos) isoforms (nos1, nos2, and nos3) expressed in human normal kidney, and soluble guanylyl cyclase, the well-known target for nitric oxide. |
2004-03-19 |
2023-08-12 |
human |
| May Ali, Siew-Kim Khoo, Stephen Turner, Stephen Stick, Peter Le Souëf, Peter Frankli. NOS1 polymorphism is associated with atopy but not exhaled nitric oxide levels in healthy children. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology. vol 14. issue 4. 2004-02-20. PMID:12911502. |
nos1 polymorphism is associated with atopy but not exhaled nitric oxide levels in healthy children. |
2004-02-20 |
2023-08-12 |
Not clear |
| Mark Arundine, Teresa Sanelli, Bei Ping He, Michael J Stron. NMDA induces NOS 1 translocation to the cell membrane in NGF-differentiated PC 12 cells. Brain research. vol 976. issue 2. 2003-07-28. PMID:12763249. |
glutamatergic-mediated nitric oxide (no) production occurs via the n-methyl-d-aspartic acid (nmda) postsynaptic density protein 95 (psd95)-neuronal nitric oxide synthase (nos1) ternary complex. |
2003-07-28 |
2023-08-12 |
Not clear |
| Mickaël Naassila, Olivier Pierrefiche, Françoise J Beaugé, Nadia Sébire, Martine Daous. Chronic ethanol exposure differentially regulates NOS1 mRNA levels depending on rat brain area. Neuroscience letters. vol 338. issue 3. 2003-05-07. PMID:12581836. |
several works have suggested a potential role for nitric oxide in alcohol-seeking behavior and we have recently shown that the specific blockade of the expression of the neuronal nitric oxide synthase (nos1) decreases rat ethanol intake. |
2003-05-07 |
2023-08-12 |
rat |
| Volker Straub, Felix Ratjen, Helge Amthor, Thomas Voit, Hartmut Graseman. Airway nitric oxide in Duchenne muscular dystrophy. The Journal of pediatrics. vol 141. issue 1. 2002-08-07. PMID:12091865. |
these findings provide indirect evidence that nos1 contributes significantly to fractional exhaled nitric oxide in healthy children. |
2002-08-07 |
2023-08-12 |
human |
| H Grasemann, K Storm van's Gravesande, S Gärtig, M Kirsch, R Büscher, J M Drazen, F Ratje. Nasal nitric oxide levels in cystic fibrosis patients are associated with a neuronal NO synthase (NOS1) gene polymorphism. Nitric oxide : biology and chemistry. vol 6. issue 2. 2002-06-19. PMID:11890749. |
nasal nitric oxide levels in cystic fibrosis patients are associated with a neuronal no synthase (nos1) gene polymorphism. |
2002-06-19 |
2023-08-12 |
Not clear |
| M Kakoki, A P Zou, D L Mattso. The influence of nitric oxide synthase 1 on blood flow and interstitial nitric oxide in the kidney. American journal of physiology. Regulatory, integrative and comparative physiology. vol 281. issue 1. 2001-07-12. PMID:11404282. |
the role of nitric oxide (no) produced by no synthase 1 (nos1) in the renal vasculature remains undetermined. |
2001-07-12 |
2023-08-12 |
rat |
| B Billack, D E Heck, D M Porterfield, R P Malchow, P J Smith, C R Gardner, D L Laskin, J D Laski. Minimal amidine structure for inhibition of nitric oxide biosynthesis. Biochemical pharmacology. vol 61. issue 12. 2001-06-14. PMID:11377388. |
formamidine was 2- to 6-fold more effective in inhibiting nitric oxide production in cells expressing inducible nitric oxide synthase (nos2) than in a cell line expressing calcium-dependent neuronal nitric oxide synthase (nos1). |
2001-06-14 |
2023-08-12 |
mouse |
| W Weichert, A Paliege, A P Provoost, S Bachman. Upregulation of juxtaglomerular NOS1 and COX-2 precedes glomerulosclerosis in fawn-hooded hypertensive rats. American journal of physiology. Renal physiology. vol 280. issue 4. 2001-04-12. PMID:11249862. |
this study describes elevated histochemical signals for nitric oxide synthase-1 (nos1) and cyclooxygenase-2 (cox-2) in juxtaglomerular apparatus (jga) and adjacent thick ascending limb of the kidney of fawn-hooded hypertensive rats (fhh). |
2001-04-12 |
2023-08-12 |
rat |
| M E Wechsler, H Grasemann, A Deykin, E K Silverman, C N Yandava, E Israel, M Wand, J M Draze. Exhaled nitric oxide in patients with asthma: association with NOS1 genotype. American journal of respiratory and critical care medicine. vol 162. issue 6. 2001-01-26. PMID:11112111. |
exhaled nitric oxide in patients with asthma: association with nos1 genotype. |
2001-01-26 |
2023-08-12 |
Not clear |
| A E Persson, S Bachman. Constitutive nitric oxide synthesis in the kidney--functions at the juxtaglomerular apparatus. Acta physiologica Scandinavica. vol 169. issue 4. 2000-11-07. PMID:10951123. |
concentration-dependent salt uptake through the na-k-2cl cotransporter located in the apical membrane of macula densa cells triggers a signal transduction cascade that involves the synthesis of nitric oxide (no) through a type 1 no synthase (nos1) which is described with respect to its complex mrna structure and regulatory aspects. |
2000-11-07 |
2023-08-12 |
Not clear |
| K Iwase, K Miyanaka, A Shimizu, A Nagasaki, T Gotoh, M Mori, M Takiguch. Induction of endothelial nitric-oxide synthase in rat brain astrocytes by systemic lipopolysaccharide treatment. The Journal of biological chemistry. vol 275. issue 16. 2000-05-10. PMID:10766821. |
in the brain, three isoforms of nitric oxide (no) synthase (nos), namely neuronal nos (nnos, nos1), inducible nos (inos, nos2), and endothelial nos (enos, nos3), have been implicated in biological roles such as neurotransmission, neurotoxicity, immune function, and blood vessel regulation, each isoform exhibiting in part overlapping roles. |
2000-05-10 |
2023-08-12 |
rat |
| H Grasemann, C N Yandava, J M Draze. Neuronal NO synthase (NOS1) is a major candidate gene for asthma. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. vol 29 Suppl 4. 2000-01-28. PMID:10641565. |
the messenger molecule nitric oxide (no), that is formed by neuronal no synthase (nos1), is known to have a key role in bronchomotor control in animals. |
2000-01-28 |
2023-08-12 |
Not clear |