| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| James Dachtler, Neil R Hardingham, Kevin Fo. The role of nitric oxide synthase in cortical plasticity is sex specific. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 43. 2013-01-07. PMID:23100421. |
nitric oxide synthase-1 (nos1) is involved in several forms of plasticity including hippocampal-dependent learning and memory, experience-dependent plasticity in the barrel cortex, and long-term potentiation (ltp) in the hippocampus and neocortex. |
2013-01-07 |
2023-08-12 |
mouse |
| Dorianna Sandonà, Jean-Francois Desaphy, Giulia M Camerino, Elisa Bianchini, Stefano Ciciliot, Daniela Danieli-Betto, Gabriella Dobrowolny, Sandra Furlan, Elena Germinario, Katsumasa Goto, Martina Gutsmann, Fuminori Kawano, Naoya Nakai, Takashi Ohira, Yoshitaka Ohno, Anne Picard, Michele Salanova, Gudrun Schiffl, Dieter Blottner, Antonio Musarò, Yoshinobu Ohira, Romeo Betto, Diana Conte, Stefano Schiaffin. Adaptation of mouse skeletal muscle to long-term microgravity in the MDS mission. PloS one. vol 7. issue 3. 2012-08-03. PMID:22470446. |
in addition, spaceflight induced translocation of sarcolemmal nitric oxide synthase-1 (nos1) into the cytosol in soleus but not in the fast-twitch extensor digitorum longus (edl) muscle. |
2012-08-03 |
2023-08-12 |
mouse |
| Emma J Rose, Ciara Greene, Sinead Kelly, Derek W Morris, Ian H Robertson, Ciara Fahey, Sarah Jacobson, John O'Doherty, Fiona N Newell, Jane McGrath, Arun Bokde, Hugh Garavan, Thomas Frodl, Michael Gill, Aiden P Corvin, Gary Donoho. The NOS1 variant rs6490121 is associated with variation in prefrontal function and grey matter density in healthy individuals. NeuroImage. vol 60. issue 1. 2012-07-03. PMID:22227051. |
a common polymorphism within the nitric oxide sythanse-1 (nos1) gene (rs6490121), initially identified as risk variant for schizophrenia, has been associated with variation in working memory and iq. |
2012-07-03 |
2023-08-12 |
human |
| Santosh Dahgam, Fredrik Nyberg, Lars Modig, Asa Torinsson Naluai, Anna-Carin Oli. Single nucleotide polymorphisms in the NOS2 and NOS3 genes are associated with exhaled nitric oxide. Journal of medical genetics. vol 49. issue 3. 2012-06-11. PMID:22368302. |
polymorphisms in nitric oxide synthase genes (nos1, nos2, and nos3) have been suggested to have a major impact on fraction of exhaled nitric oxide (feno), a biomarker of airway inflammation. |
2012-06-11 |
2023-08-12 |
Not clear |
| Jarrod E Church, Stefan M Gehrig, Annabel Chee, Timur Naim, Jennifer Trieu, Glenn K McConell, Gordon S Lync. Early functional muscle regeneration after myotoxic injury in mice is unaffected by nNOS absence. American journal of physiology. Regulatory, integrative and comparative physiology. vol 301. issue 5. 2011-12-22. PMID:21849632. |
nitric oxide (no) is an important signaling molecule produced in skeletal muscle primarily via the neuronal subtype of no synthase (nos1, or nnos). |
2011-12-22 |
2023-08-12 |
mouse |
| Juliane Kopf, Martin Schecklmann, Tim Hahn, Thomas Dresler, Alica C Dieler, Martin J Herrmann, Andreas J Fallgatter, Andreas Rei. NOS1 ex1f-VNTR polymorphism influences prefrontal brain oxygenation during a working memory task. NeuroImage. vol 57. issue 4. 2011-11-21. PMID:21620982. |
nitric oxide (no) synthase produces no, which serves as first and second messenger in neurons, where the protein is encoded by the nos1 gene. |
2011-11-21 |
2023-08-12 |
human |
| Andreas Reif, Martin Schecklmann, Elisa Eirich, Christian P Jacob, Tomasz A Jarczok, Sarah Kittel-Schneider, Klaus-Peter Lesch, Andreas J Fallgatter, Ann-Christine Ehli. A functional promoter polymorphism of neuronal nitric oxide synthase moderates prefrontal functioning in schizophrenia. The international journal of neuropsychopharmacology. vol 14. issue 7. 2011-11-10. PMID:21281558. |
recently, the promoter region of nitric oxide (no) synthase-i (nos-i, encoded by the gene nos1), impacting on prefrontal glutamate transmission, has repeatedly been associated with schizophrenia. |
2011-11-10 |
2023-08-12 |
Not clear |
| Takenori Okumura, Tomo Okochi, Taro Kishi, Masashi Ikeda, Tsuyoshi Kitajima, Yoko Kinoshita, Kunihiro Kawashima, Tomoko Tsunoka, Yasuhisa Fukuo, Toshiya Inada, Mitsuhiko Yamada, Naohisa Uchimura, Masaomi Iyo, Ichiro Sora, Norio Ozaki, Hiroshi Ujike, Nakao Iwat. Genetic Association Analysis of NOS1 and Methamphetamine-Induced Psychosis Among Japanese. Current neuropharmacology. vol 9. issue 1. 2011-11-10. PMID:21886582. |
the neuronal nitric oxide synthase gene (nos1) is located at 12q24, a susceptibility region for schizophrenia, and produces nitric oxide (no). |
2011-11-10 |
2023-08-12 |
human |
| Arnau Hervera, Roger Negrete, Sergi Leánez, Jesús M Martín-Campos, Olga Po. Peripheral effects of morphine and expression of μ-opioid receptors in the dorsal root ganglia during neuropathic pain: nitric oxide signaling. Molecular pain. vol 7. 2011-10-04. PMID:21486477. |
we investigated if nitric oxide synthesized by neuronal (nos1) or inducible (nos2) nitric oxide synthases could modulate the local antiallodynic effects of morphine through the peripheral nitric oxide-cgmp-protein kinase g (pkg)-atp-sensitive k+ (katp) channels signaling pathway activation and affect the dorsal root ganglia mor expression during neuropathic pain. |
2011-10-04 |
2023-08-12 |
Not clear |
| Arnau Hervera, Roger Negrete, Sergi Leánez, Jesús M Martín-Campos, Olga Po. The spinal cord expression of neuronal and inducible nitric oxide synthases and their contribution in the maintenance of neuropathic pain in mice. PloS one. vol 5. issue 12. 2011-07-05. PMID:21179208. |
nitric oxide generated by neuronal (nos1), inducible (nos2) or endothelial (nos3) nitric oxide synthases contributes to pain processing, but the exact role of nos1 and nos2 in the maintenance of chronic peripheral neuropathic pain as well as the possible compensatory changes in their expression in the spinal cord of wild type (wt) and nos knockout (ko) mice at 21 days after total sciatic nerve ligation remains unknown. |
2011-07-05 |
2023-08-12 |
mouse |
| M T Salam, T M Bastain, E B Rappaport, T Islam, K Berhane, W J Gauderman, F D Gillilan. Genetic variations in nitric oxide synthase and arginase influence exhaled nitric oxide levels in children. Allergy. vol 66. issue 3. 2011-05-23. PMID:21039601. |
in the nitric oxide (no) synthesis pathway, nitric oxide synthases (encoded by nos1, nos2a, and nos3) and arginases (encoded by arg1 and arg2) compete for l-arginine. |
2011-05-23 |
2023-08-12 |
Not clear |
| Sofie Trajanovska, John A Donal. Endothelial nitric oxide synthase in the amphibian, Xenopus tropicalis. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. vol 158. issue 4. 2011-05-12. PMID:21199680. |
nitric oxide (no) is generated by no synthase (nos) of which there are three isoforms: neuronal nos (nnos, nos1), inducible nos (inos, nos2), and endothelial nos (enos, nos3). |
2011-05-12 |
2023-08-12 |
xenopus_laevis |
| Arnau Hervera, Roger Negrete, Sergi Leánez, Jesús Martín-Campos, Olga Po. The role of nitric oxide in the local antiallodynic and antihyperalgesic effects and expression of delta-opioid and cannabinoid-2 receptors during neuropathic pain in mice. The Journal of pharmacology and experimental therapeutics. vol 334. issue 3. 2010-09-23. PMID:20498253. |
we investigated whether nitric oxide synthesized by neuronal (nos1) or inducible (nos2) nitric-oxide synthases could modulate dopr and/or cb2r antiallodynic and antihyperalgesic effects through the peripheral nitric oxide-cgmp-protein kinase g (pkg) pathway activation and affect their expression during neuropathic pain. |
2010-09-23 |
2023-08-12 |
mouse |
| Arnau Hervera, Roger Negrete, Sergi Leánez, Jesús Martín-Campos, Olga Po. The role of nitric oxide in the local antiallodynic and antihyperalgesic effects and expression of delta-opioid and cannabinoid-2 receptors during neuropathic pain in mice. The Journal of pharmacology and experimental therapeutics. vol 334. issue 3. 2010-09-23. PMID:20498253. |
results suggest that inactivation of the nitric oxide-cgmp-pkg peripheral pathway triggered by nos1 and nos2 enhanced the peripheral actions of dopr and cb2r agonists and that nitric oxide synthesized by nos1 is implicated in the peripheral regulation of dopr and cb2r gene transcription during neuropathic pain. |
2010-09-23 |
2023-08-12 |
mouse |
| José M Morán, Miguel A Ortiz-Ortiz, Luz M Ruiz-Mesa, Mireia Niso-Santano, Jose M Bravosanpedro, Rubén Gómez Sánchez, Rosa A González-Polo, José M Fuente. Effect of paraquat exposure on nitric oxide-responsive genes in rat mesencephalic cells. Nitric oxide : biology and chemistry. vol 23. issue 1. 2010-09-02. PMID:20388547. |
to better understand the actions of nitric oxide and its potential role in paraquat-induced gene expression, we examined changes in gch1, arg1, arg2, nos1, nos2, nos3, nostrin, nosip, nos1ap, rasd1, dynll1, gucy1a3, ddah1, ddah2 and cygb genes whose expression is controlled by or involved in signaling by the second messenger nitric oxide, in rat mesencephalic cells after 3, 6, 12 and 24h of paraquat exposure. |
2010-09-02 |
2023-08-12 |
rat |
| Fredrik Palm, Angelica Fasching, Peter Hansell, Orjan Källsko. Nitric oxide originating from NOS1 controls oxygen utilization and electrolyte transport efficiency in the diabetic kidney. American journal of physiology. Renal physiology. vol 298. issue 2. 2010-03-09. PMID:19923416. |
nitric oxide originating from nos1 controls oxygen utilization and electrolyte transport efficiency in the diabetic kidney. |
2010-03-09 |
2023-08-12 |
rat |
| Farideh Beigi, Behzad N Oskouei, Meizi Zheng, Carol A Cooke, Guillaume Lamirault, Joshua M Har. Cardiac nitric oxide synthase-1 localization within the cardiomyocyte is accompanied by the adaptor protein, CAPON. Nitric oxide : biology and chemistry. vol 21. issue 3-4. 2010-01-25. PMID:19800018. |
the mechanism(s) regulating nitric oxide synthase-1 (nos1) localization within the cardiac myocyte in health and disease remains unknown. |
2010-01-25 |
2023-08-12 |
mouse |
| Sergi Leánez, Arnau Hervera, Olga Po. Peripheral antinociceptive effects of mu- and delta-opioid receptor agonists in NOS2 and NOS1 knockout mice during chronic inflammatory pain. European journal of pharmacology. vol 602. issue 1. 2009-10-07. PMID:19041302. |
the aim of this study is to investigate the involvement of nitric oxide synthesized by the inducible (nos2) or neuronal (nos1) nitric oxide synthases in the local antinociceptive effects produced by micro- and delta-opioid receptor agonists during chronic inflammatory pain. |
2009-10-07 |
2023-08-12 |
mouse |
| Sergi Leánez, Arnau Hervera, Olga Po. Peripheral antinociceptive effects of mu- and delta-opioid receptor agonists in NOS2 and NOS1 knockout mice during chronic inflammatory pain. European journal of pharmacology. vol 602. issue 1. 2009-10-07. PMID:19041302. |
these results indicate the different roles played by nitric oxide synthesized by nos2 or nos1 in the maintenance of mechanical allodynia and thermal hyperalgesia induced by chronic inflammatory pain as well as, in the antinociceptive effects produced by micro- and delta-opioid receptor agonists during peripheral inflammatory pain. |
2009-10-07 |
2023-08-12 |
mouse |
| Takenori Okumura, Tomo Okochi, Taro Kishi, Masashi Ikeda, Tsuyoshi Kitajima, Yoshio Yamanouchi, Yoko Kinoshita, Kunihiro Kawashima, Tomoko Tsunoka, Hiroshi Ujike, Toshiya Inada, Norio Ozaki, Nakao Iwat. No association between polymorphisms of neuronal oxide synthase 1 gene (NOS1) and schizophrenia in a Japanese population. Neuromolecular medicine. vol 11. issue 2. 2009-10-05. PMID:19513863. |
the neuronal nitric oxide synthase gene (nos1) is located on 12q24, in a susceptibility region for schizophrenia, and produces nitric oxide (no) in the brain. |
2009-10-05 |
2023-08-12 |
Not clear |