| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dana B Hancock, Eden R Martin, Jeffery M Vance, William K Scot. Nitric oxide synthase genes and their interactions with environmental factors in Parkinson's disease. Neurogenetics. vol 9. issue 4. 2009-06-15. PMID:18663495. |
nitric oxide synthase (nos) genes (nos1, nos2a, and nos3) may create excess nitric oxide that contributes to neurodegeneration in parkinson's disease (pd). |
2009-06-15 |
2023-08-12 |
human |
| Gabriel L Fiszman, María C Middonno, Eulalia de la Torre, Mariana Farina, Alejandro J Español, María E Sale. Activation of muscarinic cholinergic receptors induces MCF-7 cells proliferation and angiogenesis by stimulating nitric oxide synthase activity. Cancer biology & therapy. vol 6. issue 7. 2009-04-23. PMID:17611397. |
nos1 and nos3 isoforms are expressed in mcf-7 cells and its activation by carb triggers nitric oxide synthesis and vascular endothelial growth factor expression increasing blood vessels formation induced by mammary tumor cells in vivo. |
2009-04-23 |
2023-08-12 |
mouse |
| Konstantinos Tziomalos, Joshua M Har. Role of xanthine oxidoreductase in cardiac nitroso-redox imbalance. Frontiers in bioscience (Landmark edition). vol 14. 2009-04-07. PMID:19273066. |
in this regard, xor interacts with nitric oxide signaling at numerous levels, including a direct protein-protein interaction with neuronal nitric oxide synthase (nos1) in the sarcoplasmic reticulum. |
2009-04-07 |
2023-08-12 |
Not clear |
| Michele Salanova, Gudrun Schiffl, Jörn Rittweger, Dieter Felsenberg, Dieter Blottne. Ryanodine receptor type-1 (RyR1) expression and protein S-nitrosylation pattern in human soleus myofibres following bed rest and exercise countermeasure. Histochemistry and cell biology. vol 130. issue 1. 2009-03-09. PMID:18283481. |
confocal and biochemical analysis confirmed subcellular co-localisation and protein-protein interaction of ryr1 with nitric oxide (no)-synthase type-1 (nos1). |
2009-03-09 |
2023-08-12 |
human |
| David L Carbone, Julie A Moreno, Ronald B Tjalken. Nuclear factor kappa-B mediates selective induction of neuronal nitric oxide synthase in astrocytes during low-level inflammatory stimulation with MPTP. Brain research. vol 1217. 2008-09-09. PMID:18508038. |
the data presented here demonstrate that mild activation of primary astrocytes with low or 'sub-optimal' concentrations of mptp (1 microm) and the inflammatory cytokine tumor necrosis factor alpha (10 pg/ml) and interferon gamma (1 ng/ml) results in selective induction of nos1 mrna and protein, increased production of nitric oxide (no), and a significant elevation in global protein nitration. |
2008-09-09 |
2023-08-12 |
human |
| A Sasaki, T Mabuchi, K Serizawa, I Takasaki, T Andoh, K Shiraki, S Ito, Y Kuraish. Different roles of nitric oxide synthase-1 and -2 between herpetic and postherpetic allodynia in mice. Neuroscience. vol 150. issue 2. 2008-04-03. PMID:17997045. |
the results suggest that herpetic and postherpetic allodynia is mediated by nitric oxide in the dorsal horn and that nos2 and nos1 are responsible for herpetic and postherpetic allodynia, respectively. |
2008-04-03 |
2023-08-12 |
mouse |
| Jennifer S Pollock, David M Polloc. Endothelin and NOS1/nitric oxide signaling and regulation of sodium homeostasis. Current opinion in nephrology and hypertension. vol 17. issue 1. 2008-02-14. PMID:18090673. |
next, this review will outline the progression of data providing support for our hypothesis that an intra-renal mechanism of endothelin activation of etb receptors stimulates nos1 activity and nitric oxide production to promote sodium excretion. |
2008-02-14 |
2023-08-12 |
Not clear |
| Jennifer C Sullivan, Eric J Smart, David M Pollock, Jennifer S Polloc. Influence of salt on subcellular localization of nitric oxide synthase activity and expression in the renal inner medulla. Clinical and experimental pharmacology & physiology. vol 35. issue 2. 2008-01-31. PMID:17892502. |
in addition, subcellular localization of both nos1 and nos3 has been shown to regulate enzymatic activity and influence the ability of nos to produce nitric oxide (no). |
2008-01-31 |
2023-08-12 |
rat |
| Pierre-André Scott, André Tremblay, Michèle Brochu, Jean St-Loui. Vasorelaxant action of 17 -estradiol in rat uterine arteries: role of nitric oxide synthases and estrogen receptors. American journal of physiology. Heart and circulatory physiology. vol 293. issue 6. 2008-01-31. PMID:17951367. |
part of this effect, in np rats only, is due to nitric oxide produced from muscle nos1. |
2008-01-31 |
2023-08-12 |
rat |
| B Martínez, K Barrios, C Vergara, D Mercado, S Jiménez, L Gusmão, L Caraball. A NOS1 gene polymorphism associated with asthma and specific immunoglobulin E response to mite allergens in a Colombian population. International archives of allergy and immunology. vol 144. issue 2. 2007-11-13. PMID:17536218. |
nitric oxide (no) is involved in asthma pathogenesis and is synthesized by three isoforms of no synthase, one of them encoded by nos1 gene. |
2007-11-13 |
2023-08-12 |
Not clear |
| J Shan, P Carbonara, N Karp, M Tulic, Q Hamid, D H Eidelma. Localization and distribution of NOS1 in murine airways. Nitric oxide : biology and chemistry. vol 17. issue 1. 2007-09-14. PMID:17574882. |
nevertheless, how nitric oxide production by nos1 contributes to airway responsiveness remains unclear. |
2007-09-14 |
2023-08-12 |
mouse |
| Doug W Smith, Hyder A Jinna. Role of neuronal nitric oxide in the dopamine deficit of HPRT-deficient mice. Metabolic brain disease. vol 22. issue 1. 2007-07-18. PMID:17265179. |
these results indicate that nos1 produced nitric oxide does not contribute to the dopamine deficit seen in hprt deficiency. |
2007-07-18 |
2023-08-12 |
mouse |
| Mingui Zhao, Xin Zhao, Yuxia Wu, Lixin Zhan. Enhanced sensitivity to oxidative stress in an Arabidopsis nitric oxide synthase mutant. Journal of plant physiology. vol 164. issue 6. 2007-07-12. PMID:16690168. |
the possible involvement of nitric oxide (no) in oxidative stress tolerance was studied using arabidopsis thaliana wild type (wt) and atnos1 mutant plants, in which endogenous no production is greatly diminished because 80% of nitric oxide synthase (nos) activity is eliminated due to t-dna insertion in the first exon of the nos1 gene. |
2007-07-12 |
2023-08-12 |
Not clear |
| Kejing Chen, Aleksander S Pope. Vascular and perivascular nitric oxide release and transport: biochemical pathways of neuronal nitric oxide synthase (NOS1) and endothelial nitric oxide synthase (NOS3). Free radical biology & medicine. vol 42. issue 6. 2007-05-24. PMID:17320763. |
vascular and perivascular nitric oxide release and transport: biochemical pathways of neuronal nitric oxide synthase (nos1) and endothelial nitric oxide synthase (nos3). |
2007-05-24 |
2023-08-12 |
Not clear |
| M Golder, D E Burleigh, L Ghali, R M Feakins, P J Lunniss, N S Williams, H A Navsari. Longitudinal muscle shows abnormal relaxation responses to nitric oxide and contains altered levels of NOS1 and elastin in uncomplicated diverticular disease. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland. vol 9. issue 3. 2007-04-20. PMID:17298619. |
longitudinal muscle shows abnormal relaxation responses to nitric oxide and contains altered levels of nos1 and elastin in uncomplicated diverticular disease. |
2007-04-20 |
2023-08-12 |
Not clear |
| Michael W Epperly, Shaonan Cao, Xichen Zhang, Darcy Franicola, Hongmei Shen, Emily E Greenberger, Laura D Epperly, Joel S Greenberge. Increased longevity of hematopoiesis in continuous bone marrow cultures derived from NOS1 (nNOS, mtNOS) homozygous recombinant negative mice correlates with radioresistance of hematopoietic and marrow stromal cells. Experimental hematology. vol 35. issue 1. 2007-03-01. PMID:17198882. |
neuronal nitric oxide synthase (nos1, mitochondrial nos, neuronal nos) homozygous deletion recombinant negative mice demonstrate ionizing irradiation resistance in vivo, attributable to the decrease in mitochondrial-localized production of peroxynitrite, a potent lipid toxic free radical species resulting from the combination of nitric oxide and superoxide. |
2007-03-01 |
2023-08-12 |
mouse |
| Allan D Shapir. Nitric oxide signaling in plants. Vitamins and hormones. vol 72. 2006-05-10. PMID:16492476. |
nitric oxide function in drought/abscisic acid (aba)-induction of stomatal closure requires nitrate reductase and nos1. |
2006-05-10 |
2023-08-12 |
Not clear |
| Fang-Qing Guo, Nigel M Crawfor. Arabidopsis nitric oxide synthase1 is targeted to mitochondria and protects against oxidative damage and dark-induced senescence. The Plant cell. vol 17. issue 12. 2006-01-31. PMID:16272429. |
the arabidopsis thaliana protein nitric oxide synthase1 (nos1) is needed for nitric oxide (no) synthesis and signaling during defense responses, hormonal signaling, and flowering. |
2006-01-31 |
2023-08-12 |
Not clear |
| Pei Tsai, John Weaver, Guan Liang Cao, Sovitj Pou, Linda J Roman, Anatoly A Starkov, Gerald M Rose. L-arginine regulates neuronal nitric oxide synthase production of superoxide and hydrogen peroxide. Biochemical pharmacology. vol 69. issue 6. 2005-04-12. PMID:15748708. |
as the concentration of l-arginine and n(omega)-hydroxyl-l-arginine increases, the rate of nadph consumption for h(4)b-bound nos1 decreased resulting in lower rates of both o(2)(*-) and h(2)o(2) generation, while increasing the rate of nitric oxide (*no) production. |
2005-04-12 |
2023-08-12 |
Not clear |
| Shakil A Khan, Kwangho Lee, Khalid M Minhas, Daniel R Gonzalez, Shubha V Y Raju, Ankit D Tejani, Dechun Li, Dan E Berkowitz, Joshua M Har. Neuronal nitric oxide synthase negatively regulates xanthine oxidoreductase inhibition of cardiac excitation-contraction coupling. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 45. 2004-12-28. PMID:15486091. |
these data demonstrate a unique interaction between a nitric oxide and an o(2)(.-) -generating enzyme that accounts for crosstalk between these signaling pathways; these findings demonstrate a direct antioxidant mechanism for nos1 and have pathophysiologic implications for the growing number of disease states in which increased xor activity plays a role. |
2004-12-28 |
2023-08-12 |
Not clear |