| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Patricia Moreno, Rafael Alves Cazuza, Joyce Mendes-Gomes, Andrés Felipe Díaz, Sara Polo, Sergi Leánez, Christie Ramos Andrade Leite-Panissi, Olga Po. The Effects of Cobalt Protoporphyrin IX and Tricarbonyldichlororuthenium (II) Dimer Treatments and Its Interaction with Nitric Oxide in the Locus Coeruleus of Mice with Peripheral Inflammation. International journal of molecular sciences. vol 20. issue 9. 2019-08-21. PMID:31060340. |
in wild-type (wt) and knockout mice for neuronal (nos1-ko) or inducible (nos2-ko) nitric oxide synthases with inflammatory pain induced by complete freund's adjuvant (cfa), we assessed: 1) antinociceptive actions of cobalt protoporphyrin ix (copp), an ho-1 inducer; 2) effects of copp and tricarbonyldichlororuthenium(ii)dimer (corm-2), a carbon monoxide-liberating compound, on the expression of ho-1, nos1, nos2, cd11b/c, gfap,and mitogen-activated protein kinases (mapk)in the lc. |
2019-08-21 |
2023-08-13 |
mouse |
| Paulina Wigner, Piotr Czarny, Ewelina Synowiec, Michał Bijak, Katarzyna Białek, Monika Talarowska, Piotr Galecki, Janusz Szemraj, Tomasz Sliwinsk. Variation of genes involved in oxidative and nitrosative stresses in depression. European psychiatry : the journal of the Association of European Psychiatrists. vol 48. 2018-12-18. PMID:29331597. |
in this study, we examined the association between single-nucleotide polymorphisms of the genes encoding sod2 (superoxide dismutase 2), cat (catalase), gpx4 (glutathione peroxidase 4), nos1 (nitric oxide synthase 1), nos2 (nitric oxide synthase 2), and the development of depressive disorders. |
2018-12-18 |
2023-08-13 |
cat |
| Shiek S S J Ahmed, R S Akram Husain, Suresh Kumar, V Ramakrishna. Association Between NOS1 Gene Polymorphisms and Schizophrenia in Asian and Caucasian Populations: A Meta-Analysis. Neuromolecular medicine. vol 19. issue 2-3. 2018-08-06. PMID:28795310. |
several investigations have focused on determining the association between nos1 (nitric oxide synthase-1) polymorphisms and risk of schizophrenia (sz). |
2018-08-06 |
2023-08-13 |
Not clear |
| Liang Wei, Qi Wang, Yanfei Zhang, Cheng Yang, Hongxin Guan, Yiming Chen, Zhiyang Su. Identification of key genes, transcription factors and microRNAs involved in intracranial aneurysm. Molecular medicine reports. vol 17. issue 1. 2018-07-09. PMID:29115560. |
in addition, nitric oxide synthase 1 (nos1), a target of mirna‑125b, and myosin heavy chain 11 (myh11), a target of minichromosome maintenance complex component 4 (mcm4), had higher degree scores in the integrated network. |
2018-07-09 |
2023-08-13 |
Not clear |
| Gustavo H Oliveira-Paula, Riccardo Lacchini, Jose E Tanus-Santo. Clinical and pharmacogenetic impact of endothelial nitric oxide synthase polymorphisms on cardiovascular diseases. Nitric oxide : biology and chemistry. vol 63. 2018-07-05. PMID:27569446. |
nitric oxide (no) is a vasoactive substance synthesized from l-arginine by neuronal (nos1), endothelial (nos3), and inducible (nos2) nitric oxide synthases. |
2018-07-05 |
2023-08-13 |
Not clear |
| Esther Roselló-Lletí, Estefanía Tarazón, Ana Ortega, Carolina Gil-Cayuela, Ricardo Carnicer, Francisca Lago, Jose Ramón González-Juanatey, Manuel Portolés, Miguel River. Protein Inhibitor of NOS1 Plays a Central Role in the Regulation of NOS1 Activity in Human Dilated Hearts. Scientific reports. vol 6. 2018-06-26. PMID:27481317. |
an essential factor for the production of nitric oxide by nitric oxide synthase 1 (nos1), major modulator of cardiac function, is the cofactor tetrahydrobiopterin (bh4). |
2018-06-26 |
2023-08-13 |
human |
| Barbora Piknova, Ji Won Park, Kai Kwan Jeff Lam, Alan N Schechte. Nitrate as a source of nitrite and nitric oxide during exercise hyperemia in rat skeletal muscle. Nitric oxide : biology and chemistry. vol 55-56. 2018-01-26. PMID:27000467. |
the presence of nitric oxide (no) synthase enzymes, mainly the nos1 isoform, in skeletal muscle had been well established; however in the last decade it has been realized that no may also be produced by reduction of nitrate and tissue nitrite. |
2018-01-26 |
2023-08-13 |
rat |
| Jie Wang, Lei Jin, Yufu Zhu, Xiuping Zhou, Rutong Yu, Shangfeng Ga. Research progress in NOS1AP in neurological and psychiatric diseases. Brain research bulletin. vol 125. 2017-10-30. PMID:27237129. |
the pdz ligand motif of nos1ap binds to the pdz domain of nos1, the enzyme responsible for nitric oxide synthesis in the nervous system. |
2017-10-30 |
2023-08-13 |
rat |
| Yang Wang, Tatiana Veremeyko, Andus Hon-Kit Wong, Rachid El Fatimy, Zhiyun Wei, Wei Cai, Anna M Krichevsk. Downregulation of miR-132/212 impairs S-nitrosylation balance and induces tau phosphorylation in Alzheimer's disease. Neurobiology of aging. vol 51. 2017-09-28. PMID:28089352. |
inhibition of mir-132 in primary human neurons and neural cells leads to increased nos1 levels and triggers excessive production of nitric oxide, followed by aberrant s-nitrosylation (sno) of specific proteins associated with neurodegeneration and tau pathology, such as cyclin-dependent kinase 5, dynamin-related protein 1, and glyceraldehyde-3-phosphate dehydrogenase. |
2017-09-28 |
2023-08-13 |
human |
| Wei Yin, Kevin Clare, Qiujia Zhang, Nora D Volkow, Congwu D. Chronic cocaine induces HIF-VEGF pathway activation along with angiogenesis in the brain. PloS one. vol 12. issue 4. 2017-09-06. PMID:28448515. |
for this purpose we measured nitric oxide (no) concentration in plasma, brain neuronal nitric oxide synthase (nnos or nos1), hif-1α, and vegf expression in different brain regions, i.e., middle prefrontal cortex, somatosensory cortex, nucleus accumbens, and dorsal striatum, using elisa or western blot. |
2017-09-06 |
2023-08-13 |
rat |
| Kelly Anne Hyndman, Courtney Dugas, Alexandra M Arguello, Traci T Goodchild, Kathleen M Buckley, Mariah Burch, Masashi Yanagisawa, Jennifer S Polloc. High salt induces autocrine actions of ET-1 on inner medullary collecting duct NO production via upregulated ETB receptor expression. American journal of physiology. Regulatory, integrative and comparative physiology. vol 311. issue 2. 2017-06-26. PMID:27280426. |
the collecting duct endothelin-1 (et-1), endothelin b (etb) receptor, and nitric oxide synthase-1 (nos1) pathways are critical for regulation of fluid-electrolyte balance and blood pressure control during high-salt feeding. |
2017-06-26 |
2023-08-13 |
mouse |
| Dagmar Bruenig, Charles P Morris, Divya Mehta, Wendy Harvey, Bruce Lawford, Ross McD Young, Joanne Voise. Nitric oxide pathway genes (NOS1AP and NOS1) are involved in PTSD severity, depression, anxiety, stress and resilience. Gene. vol 625. 2017-06-15. PMID:28465168. |
nitric oxide pathway genes (nos1ap and nos1) are involved in ptsd severity, depression, anxiety, stress and resilience. |
2017-06-15 |
2023-08-13 |
Not clear |
| Dagmar Bruenig, Charles P Morris, Divya Mehta, Wendy Harvey, Bruce Lawford, Ross McD Young, Joanne Voise. Nitric oxide pathway genes (NOS1AP and NOS1) are involved in PTSD severity, depression, anxiety, stress and resilience. Gene. vol 625. 2017-06-15. PMID:28465168. |
this study systematically investigates two genes of the nitric oxide pathway nos1ap and nos1 for a potential involvement in ptsd, comorbidities and resilience. |
2017-06-15 |
2023-08-13 |
Not clear |
| Dagmar Bruenig, Charles P Morris, Divya Mehta, Wendy Harvey, Bruce Lawford, Ross McD Young, Joanne Voise. Nitric oxide pathway genes (NOS1AP and NOS1) are involved in PTSD severity, depression, anxiety, stress and resilience. Gene. vol 625. 2017-06-15. PMID:28465168. |
this study indicates that nos1ap and nos1 from the nitric oxide pathway are likely to play a key role in ptsd, its comorbidities and resilience. |
2017-06-15 |
2023-08-13 |
Not clear |
| Manuel Kuhn, Jan Haaker, Evelyn Glotzbach-Schoon, Dirk Schümann, Marta Andreatta, Marie-Luise Mechias, Karolina Raczka, Nina Gartmann, Christian Büchel, Andreas Mühlberger, Paul Pauli, Andreas Reif, Raffael Kalisch, Tina B Lonsdor. Converging evidence for an impact of a functional NOS gene variation on anxiety-related processes. Social cognitive and affective neuroscience. vol 11. issue 5. 2017-04-28. PMID:26746182. |
thereby, one candidate pathway is neuronal nitric oxide (no) signaling, and accordingly, rodent studies have identified no synthase (nos-i), encoded by nos1, as a strong molecular candidate for modulating anxiety and hippocampus-dependent learning processes. |
2017-04-28 |
2023-08-13 |
human |
| Yong Luan, Dongjiang Li, Lulu Gao, Sha Xie, Ling Pe. A single nucleotide polymorphism in hsa‑miR‑146a is responsible for the development of bronchial hyperresponsiveness in response to intubation during general anesthesia. Molecular medicine reports. vol 14. issue 3. 2017-04-06. PMID:27431205. |
in the present study, nitric oxide synthase 1 (nos1) was identified as a target gene of micro (mi)r‑146a using in silico analysis and luciferase assay. |
2017-04-06 |
2023-08-13 |
human |
| Xiaoyu Dong, Qiang Fu, Song Liu, Chengbin Gao, Baofeng Su, Fenghua Tan, Chao L. The expression signatures of neuronal nitric oxide synthase (NOS1) in turbot (Scophthalmus maximus L.) mucosal surfaces against bacterial challenge. Fish & shellfish immunology. vol 59. 2017-03-21. PMID:27825948. |
particularly, neuronal nos (nnos or nos1) is a constitutively expressed gene that catalyzes the oxidation of l-arginine and water to nitric oxide (no), which is known as a potent host defence effector in immune system with antimicrobial activity. |
2017-03-21 |
2023-08-13 |
Not clear |
| Alejandro Javier Español, Agustina Salem, Daniela Rojo, María Elena Sale. Participation of non-neuronal muscarinic receptors in the effect of carbachol with paclitaxel on human breast adenocarcinoma cells. Roles of nitric oxide synthase and arginase. International immunopharmacology. vol 29. issue 1. 2016-09-14. PMID:25812766. |
the combination also increased nitric oxide production by nos1 and nos3 via machr activation, concomitantly with an up-regulation of nos3 expression. |
2016-09-14 |
2023-08-13 |
human |
| Sergei A Korneev, Mark Maconochie, Souvik Naskar, Elena I Korneeva, Guy P Richardson, Michael O'She. A novel long non-coding natural antisense RNA is a negative regulator of Nos1 gene expression. Scientific reports. vol 5. 2016-08-10. PMID:26154151. |
nos1 produces nitric oxide (no), a major signaling molecule in the cns implicated in many important functions including neuronal differentiation and memory formation. |
2016-08-10 |
2023-08-13 |
mouse |
| Kelly A Hyndman, Alexandra M Arguello, Sofia K H Morsing, Jennifer S Polloc. Dynamin-2 is a novel NOS1β interacting protein and negative regulator in the collecting duct. American journal of physiology. Regulatory, integrative and comparative physiology. vol 310. issue 7. 2016-08-08. PMID:26791826. |
nitric oxide synthase 1 (nos1)-derived nitric oxide (no) production in collecting ducts is critical for maintaining fluid-electrolyte balance. |
2016-08-08 |
2023-08-13 |
mouse |