| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mirza Saqib Baig, Sofia V Zaichick, Mao Mao, Andre L de Abreu, Farnaz R Bakhshi, Peter C Hart, Uzma Saqib, Jing Deng, Saurabh Chatterjee, Michelle L Block, Stephen M Vogel, Asrar B Malik, Marcia E L Consolaro, John W Christman, Richard D Minshall, Benjamin N Gantner, Marcelo G Bonin. NOS1-derived nitric oxide promotes NF-κB transcriptional activity through inhibition of suppressor of cytokine signaling-1. The Journal of experimental medicine. vol 212. issue 10. 2016-04-25. PMID:26324446. |
here, we demonstrate that the low-output nitric oxide (no) synthase 1 (nos1 or nnos) plays a critical role in the inflammatory response by promoting the activity of nf-κb. |
2016-04-25 |
2023-08-13 |
mouse |
| Gustavo H Oliveira-Paula, Riccardo Lacchini, Jose E Tanus-Santo. Endothelial nitric oxide synthase: From biochemistry and gene structure to clinical implications of NOS3 polymorphisms. Gene. vol 575. issue 2 Pt 3. 2016-03-17. PMID:26428312. |
while mediator is synthesized from l-arginine by neuronal, endothelial, and inducible nitric oxide synthases (nos1,nos3 and nos2 respectively), nos3 is the most important isoform for no formation in the cardiovascular system. |
2016-03-17 |
2023-08-13 |
Not clear |
| B Umman, B Cakmakoglu, Z B Cincin, M Kocaaga, S Emet, S Tamer, C Gokkus. Identification of gene variants related to the nitric oxide pathway in patients with acute coronary syndrome. Gene. vol 574. issue 1. 2016-01-08. PMID:26232608. |
the most suspicious biomarker candidates associated with the nitric oxide pathway analysis were vascular endothelial growth factor a (vegfa), methionine sulfoxide reductase a (msra), nitric oxide synthase 1 (nos1), and gtp cyclohydrolase i (gch-1). |
2016-01-08 |
2023-08-13 |
Not clear |
| Xiaoqiu Wang, James W Frank, Jing Xu, Kathrin A Dunlap, M Carey Satterfield, Robert C Burghardt, Jared J Romero, Thomas R Hansen, Guoyao Wu, Fuller W Baze. Functional role of arginine during the peri-implantation period of pregnancy. II. Consequences of loss of function of nitric oxide synthase NOS3 mRNA in ovine conceptus trophectoderm. Biology of reproduction. vol 91. issue 3. 2015-05-22. PMID:25061098. |
for mao-nos3 conceptuses, there were no compensatory increases in the expression levels of either nitric oxide synthase-1 (nos1) or nitric oxide synthase-2 (nos2) or in expression of enzymes for synthesis of polyamines (ornithine decarboxylase, arginine decarboxylase, agmatinase) from arginine or ornithine with which to rescue development of mao-nos3 conceptuses. |
2015-05-22 |
2023-08-13 |
Not clear |
| Shang-Feng Gao, Yun-Rong Lu, Li-Gen Shi, Xue-Yan Wu, Bo Sun, Xin-Yan Fu, Jian-Hong Luo, Ai-Min Ba. Nitric oxide synthase and nitric oxide alterations in chronically stressed rats: a model for nitric oxide in major depressive disorder. Psychoneuroendocrinology. vol 47. 2015-04-16. PMID:25001963. |
nitric oxide (no) and no synthase-1 (nos1) are involved in the stress response and in depression. |
2015-04-16 |
2023-08-13 |
rat |
| Yin Hua Zhang, Chun Zi Jin, Ji Hyun Jang, Yue Wan. Molecular mechanisms of neuronal nitric oxide synthase in cardiac function and pathophysiology. The Journal of physiology. vol 592. issue 15. 2015-04-13. PMID:24756636. |
neuronal nitric oxide synthase (nnos or nos1) is the major endogenous source of myocardial nitric oxide (no), which facilitates cardiac relaxation and modulates contraction. |
2015-04-13 |
2023-08-13 |
Not clear |
| Amy K Sutton, Hongjuan Pei, Korri H Burnett, Martin G Myers, Christopher J Rhodes, David P Olso. Control of food intake and energy expenditure by Nos1 neurons of the paraventricular hypothalamus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 46. 2015-02-09. PMID:25392498. |
the pvh contains nitric oxide synthase-1 (nos1)-expressing (nos1(pvh)) neurons of unknown function; these represent a subset of the larger population of sim1-expressing pvh (sim1(pvh)) neurons. |
2015-02-09 |
2023-08-13 |
mouse |
| Lifei Tang, Honglan Wang, Mark T Ziol. Targeting NOS as a therapeutic approach for heart failure. Pharmacology & therapeutics. vol 142. issue 3. 2015-01-15. PMID:24380841. |
nitric oxide is a key signaling molecule in the heart and is produced endogenously by three isoforms of nitric oxide synthase, neuronal nos (nos1), endothelial nos (nos3), and inducible nos (nos2). |
2015-01-15 |
2023-08-12 |
Not clear |
| Rodrigo Muñoz-Castañeda, David Díaz, Carmelo A Avila-Zarza, José R Alonso, Eduardo Weruag. Sex-influence of nicotine and nitric oxide on motor coordination and anxiety-related neurophysiological responses. Psychopharmacology. vol 231. issue 4. 2014-10-10. PMID:24081550. |
nitric oxide (no) is a messenger synthesized in both the neuronal and glial populations by nitric oxide synthase type 1 (nos1). |
2014-10-10 |
2023-08-12 |
Not clear |
| Steven M Colvin, Kenneth Y Kwa. Dysregulated nitric oxide signaling as a candidate mechanism of fragile X syndrome and other neuropsychiatric disorders. Frontiers in genetics. vol 5. 2014-08-07. PMID:25101118. |
given the role of nitric oxide in diverse neural processes, including synaptic development and plasticity, the loss of nos1 in fxs may contribute to the etiology of the disorder. |
2014-08-07 |
2023-08-13 |
human |
| K P Lesch, S Merker, A Reif, M Nova. Dances with black widow spiders: dysregulation of glutamate signalling enters centre stage in ADHD. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 6. 2013-12-23. PMID:22939004. |
nitric oxide synthase-1, nos1). |
2013-12-23 |
2023-08-12 |
Not clear |
| Suad AlFadhli, Eiman M A Mohammed, Asmahan Al Shubail. Association analysis of nitric oxide synthases: NOS1, NOS2A and NOS3 genes, with multiple sclerosis. Annals of human biology. vol 40. issue 4. 2013-11-08. PMID:23826716. |
association analysis of nitric oxide synthases: nos1, nos2a and nos3 genes, with multiple sclerosis. |
2013-11-08 |
2023-08-12 |
Not clear |
| Kelly A Hyndman, Jing Xue, Alexander MacDonell, Joshua S Speed, Chunhua Jin, Jennifer S Polloc. Distinct regulation of inner medullary collecting duct nitric oxide production from mice and rats. Clinical and experimental pharmacology & physiology. vol 40. issue 3. 2013-08-16. PMID:23331097. |
nitric oxide (no) and no synthase 1 (nos1) maintain sodium and water homeostasis. |
2013-08-16 |
2023-08-12 |
mouse |
| b' M Gust, M Fortier, J Garric, M Fournier, F Gagn\\xc3\\xa. Effects of short-term exposure to environmentally relevant concentrations of different pharmaceutical mixtures on the immune response of the pond snail Lymnaea stagnalis. The Science of the total environment. vol 445-446. 2013-08-08. PMID:23333517.' |
effects on immunocompetence (hemocyte viability and count, ros and thiol levels, phagocytosis) and gene expression were related to the immune response and oxidative stress: catalase (cat), superoxide dismutase (sod), glutathione reductase (gr), selenium-dependent glutathione peroxidase (segpx), two isoforms of the nitric oxide synthetase gene (nos1 and nos2), molluscan defensive molecule (mdm), toll-like receptor 4 (tlr4), allograft inflammatory factor-1 (aif) and heat-shock protein 70 (hsp70). |
2013-08-08 |
2023-08-12 |
cat |
| N J Stojkov, M M Janjic, T S Kostic, S A Andri. Orally applied doxazosin disturbed testosterone homeostasis and changed the transcriptional profile of steroidogenic machinery, cAMP/cGMP signalling and adrenergic receptors in Leydig cells of adult rats. Andrology. vol 1. issue 2. 2013-07-29. PMID:23413145. |
doxa application more affected cgmp signalling: stimulated transcription of constitutive nitric oxide synthases (nos1, nos3) in time-dependent manner, whereas reduced inducible nos2. |
2013-07-29 |
2023-08-12 |
rat |
| Steve R Roof, Lifei Tang, Joseph E Ostler, Muthu Periasamy, Sandor Györke, George E Billman, Mark T Ziol. Neuronal nitric oxide synthase is indispensable for the cardiac adaptive effects of exercise. Basic research in cardiology. vol 108. issue 2. 2013-07-18. PMID:23377961. |
ventricular myocytes from ex mice had increased nos1 expression and nitric oxide production compared to myocytes from sed mice. |
2013-07-18 |
2023-08-12 |
mouse |
| Anna Jezierski, Paromita Deb-Rinker, Caroline Sodja, P Roy Walker, Dao Ly, Julie Haukenfrers, Jagdeep K Sandhu, Mahmud Bani-Yaghoub, Marianna Sikorsk. Involvement of NOS3 in RA-Induced neural differentiation of human NT2/D1 cells. Journal of neuroscience research. vol 90. issue 12. 2013-04-11. PMID:22987726. |
no is synthesized from the amino acid l-arginine by nitric oxide synthases (nos1, nos2, and nos3), which are encoded by separate genes and display different tissue distributions. |
2013-04-11 |
2023-08-12 |
human |
| b' M Gust, M Fortier, J Garric, M Fournier, F Gagn\\xc3\\xa. Immunotoxicity of surface waters contaminated by municipal effluents to the snail Lymnaea stagnalis. Aquatic toxicology (Amsterdam, Netherlands). vol 126. 2013-02-15. PMID:23021492.' |
changes in mrna expression of some genes in the hemocytes were also assessed after 7d of exposure, as follows: genes coding for catalase (cat), superoxide dismutase (sod), glutathione reductase (gsr), selenium-dependent glutathione peroxidase (segpx), two isoforms of the nitric oxide synthetase (nos1 and nos2), molluscan defensive molecule (mdm), toll-like receptor 4 (tlr4), allograft inflammatory factor-1 (aif), and heat-shock protein 70 (hsp70). |
2013-02-15 |
2023-08-12 |
cat |
| Therese O'Donoghue, Derek W Morris, Ciara Fahey, Andreia Da Costa, John J Foxe, Doreen Hoerold, Daniela Tropea, Michael Gill, Aiden Corvin, Gary Donoho. A NOS1 variant implicated in cognitive performance influences evoked neural responses during a high density EEG study of early visual perception. Human brain mapping. vol 33. issue 5. 2013-01-22. PMID:21520349. |
the nitric oxide synthasase-1 gene (nos1) has been implicated in mental disorders including schizophrenia and variation in cognition. |
2013-01-22 |
2023-08-12 |
human |
| Michael J Cutler, Bradley N Plummer, Xiaoping Wan, Qi-An Sun, Douglas Hess, Haiyan Liu, Isabelle Deschenes, David S Rosenbaum, Jonathan S Stamler, Kenneth R Laurit. Aberrant S-nitrosylation mediates calcium-triggered ventricular arrhythmia in the intact heart. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 44. 2013-01-08. PMID:23071315. |
nitric oxide (no) derived from the activity of neuronal nitric oxide synthase (nos1) is involved in s-nitrosylation of key sarcoplasmic reticulum (sr) ca(2+) handling proteins. |
2013-01-08 |
2023-08-12 |
Not clear |