| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ioannis K Rizos, James N Tsoporis, Ioannis K Toumpoulis, Vasileios Salpeas, Shehla Izhar, Angelos G Rigopoulos, Eleftherios A Sakadakis, Thomas G Parke. Antiapoptotic Effect of β1 Blockers in Ascending Thoracic Aortic Smooth Muscle Cells: The Role of HSP70 Expression. Journal of cardiovascular pharmacology. vol 72. issue 2. 2019-06-10. PMID:29738368. |
in vitro, metoprolol treatment of hypoxic rat avsmcs increased nitric oxide (no) production, induced heat shock factor 1 transport to the nucleus, upregulated hsp70, decreased p53 phosphorylation and attenuated apoptosis. |
2019-06-10 |
2023-08-13 |
human |
| Lei Zhang, Jun Zhou, Fengjiao Ma, Quanbo Wang, Hui Xu, Huangxian Ju, Jianping Le. Single-Sided Competitive Axial Coordination of G-Quadruplex/Hemin as Molecular Switch for Imaging Intracellular Nitric Oxide. Chemistry (Weinheim an der Bergstrasse, Germany). vol 25. issue 2. 2019-01-22. PMID:30407667. |
also, the proposed protocol provided a smart strategy to monitor the relationship between nitric oxide and p53 protein activity in living cells. |
2019-01-22 |
2023-08-13 |
Not clear |
| Bhawna Chandravanshi, Ramesh Ramchandra Bhond. Shielding Engineered Islets With Mesenchymal Stem Cells Enhance Survival Under Hypoxia. Journal of cellular biochemistry. vol 118. issue 9. 2017-12-26. PMID:28098405. |
this was further accompanied by reduction in total reactive oxygen species, nitric oxide, and super oxide ions and down regulation of caspase3, caspase8, p53, and up regulation of bcl2 confirming prevention of apoptosis in icas. |
2017-12-26 |
2023-08-13 |
Not clear |
| Nan-Shan Chan. Bubbling cell death: A hot air balloon released from the nucleus in the cold. Experimental biology and medicine (Maywood, N.J.). vol 241. issue 12. 2017-06-06. PMID:27075929. |
mechanistically, proapoptotic ww domain-containing oxidoreductase and p53 block the protective tnf receptor adaptor factor 2 that allows nitric oxide synthase 2 to synthesize nitric oxide and bubble formation. |
2017-06-06 |
2023-08-13 |
Not clear |
| Bryndon J Oleson, Katarzyna A Broniowska, Aaron Naatz, Neil Hogg, Vera L Tarakanova, John A Corbet. Nitric Oxide Suppresses β-Cell Apoptosis by Inhibiting the DNA Damage Response. Molecular and cellular biology. vol 36. issue 15. 2017-05-16. PMID:27185882. |
nitric oxide suppresses activation of the ddr (as measured by γh2ax formation and the phosphorylation of kap1 and p53) in response to multiple genotoxic agents, including camptothecin, h2o2, and nitric oxide itself, despite the presence of dna damage. |
2017-05-16 |
2023-08-13 |
Not clear |
| Larissa Juliani Sanches, Poliana Camila Marinello, Carolina Panis, Tatiane Renata Fagundes, José Andrés Morgado-Díaz, Julio Cesar Madureira de-Freitas-Junior, Rubens Cecchini, Alessandra Lourenço Cecchini, Rodrigo Cabral Lui. Cytotoxicity of citral against melanoma cells: The involvement of oxidative stress generation and cell growth protein reduction. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 39. issue 3. 2017-04-07. PMID:28351318. |
we observed that citral exerted antiproliferative and cytotoxic effects in b16f10; induced oxidative stress, dna lesions, and p53 nuclear translocation; and reduced nitric oxide levels and nuclear factor kappa b, erk1/2, and akt. |
2017-04-07 |
2023-08-13 |
human |
| Gurumayum Reenaroy Devi, Md Jahoor Alam, R K Brojen Sing. Synchronization in stress p53 network. Mathematical medicine and biology : a journal of the IMA. vol 32. issue 4. 2016-09-16. PMID:25713051. |
we study transition of the temporal behaviours of p53 and mdm2 in a stress p53-mdm2-no regulatory network induced by a bioactive molecule no (nitric oxide). |
2016-09-16 |
2023-08-13 |
Not clear |
| Hanan Ramadan Hamad Mohame. Estimation of TiO₂ nanoparticle-induced genotoxicity persistence and possible chronic gastritis-induction in mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 83. 2016-06-07. PMID:26072100. |
the administration of nano-tio2 resulted in persistent apoptotic dna fragmentation and mutations in p53 exons (5-8) as well as significant persistent elevations in malondialdehyde and nitric oxide levels and decreases in the reduced glutathione level and catalase activity compared with the control mice in a dose- and time-dependent manner. |
2016-06-07 |
2023-08-13 |
mouse |
| Concetta Ferretti, Guendalina Lucarini, Chiara Andreoni, Eleonora Salvolini, Novella Bianchi, Giovanni Vozzi, Antonio Gigante, Monica Mattioli-Belmont. Human Periosteal Derived Stem Cell Potential: The Impact of age. Stem cell reviews and reports. vol 11. issue 3. 2016-02-29. PMID:25239138. |
immunohistochemical detection of ki67 and p53, nitric oxide production and qrt- pcr of a selected gene panel for osteoblastic differentiation, bone remodeling and stemness were evaluated. |
2016-02-29 |
2023-08-13 |
human |
| Mokhtar I Yousef, Hend M Hussie. Cisplatin-induced renal toxicity via tumor necrosis factor-α, interleukin 6, tumor suppressor P53, DNA damage, xanthine oxidase, histological changes, oxidative stress and nitric oxide in rats: protective effect of ginseng. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 78. 2015-12-17. PMID:25640527. |
cisplatin-induced renal toxicity via tumor necrosis factor-α, interleukin 6, tumor suppressor p53, dna damage, xanthine oxidase, histological changes, oxidative stress and nitric oxide in rats: protective effect of ginseng. |
2015-12-17 |
2023-08-13 |
rat |
| Jin Gu Cho, Jun Hee Lee, Shin Hee Hong, Han Na Lee, Chul Min Kim, Seo Yoon Kim, Kang Jun Yoon, Bae Jun Oh, Jae Hyeon Kim, Seok Yoon Jung, Takayuki Asahara, Sang-Mo Kwon, Sang Gyu Par. Tauroursodeoxycholic acid, a bile acid, promotes blood vessel repair by recruiting vasculogenic progenitor cells. Stem cells (Dayton, Ohio). vol 33. issue 3. 2015-12-04. PMID:25407160. |
in addition, tudca decreased cellular senescence by reducing levels of p53, p21, and reactive oxygen species and increased nitric oxide. |
2015-12-04 |
2023-08-13 |
mouse |
| Armanda Pugnaloni, Guendalina Lucarini, Corrado Rubini, Arianna Smorlesi, Marco Tomasetti, Elisabetta Strafella, Tatiana Armeni, Alessandro F Gualtier. Raw and thermally treated cement asbestos exerts different cytotoxicity effects on A549 cells in vitro. Acta histochemica. vol 117. issue 1. 2015-09-18. PMID:25466987. |
our aim is to deepen the understanding of the biological effects on a549 cells of these materials regarding dna damage related proteins (p53, its isoform p73 and trail) and nitric oxide (no) production during inducible nitric oxide synthase (inos)-mediated inflammation. |
2015-09-18 |
2023-08-13 |
Not clear |
| Magd A Kot. Molecular mechanisms of ursodeoxycholic acid toxicity & side effects: ursodeoxycholic acid freezes regeneration & induces hibernation mode. International journal of molecular sciences. vol 13. issue 7. 2015-07-29. PMID:22942741. |
udca inhibits dna repair, co-enzyme a, cyclic amp, p53, phagocytosis, and inhibits induction of nitric oxide synthatase. |
2015-07-29 |
2023-08-12 |
Not clear |
| Ying Chen, Haiyan Sun, Liyong Huang, Juxiang Li, Wenke Zhou, Jingling Chan. Neuroprotective Effect of Radix Trichosanthis Saponins on Subarachnoid Hemorrhage. Evidence-based complementary and alternative medicine : eCAM. vol 2015. 2015-06-19. PMID:26089937. |
an established sah model was used and superoxide dismutase (sod), malondialdehyde (mda), induced nitric oxide synthase (inos), nitric oxide (no), lactate dehydrogenase (ldh), p-p38, and p53 activation were detected after 48 h of sah. |
2015-06-19 |
2023-08-13 |
Not clear |
| Jin-Ying Zhang, Fan Zhang, Chao-Qun Hong, Armando E Giuliano, Xiao-Jiang Cui, Guang-Ji Zhou, Guo-Jun Zhang, Yu-Kun Cu. Critical protein GAPDH and its regulatory mechanisms in cancer cells. Cancer biology & medicine. vol 12. issue 1. 2015-04-10. PMID:25859407. |
several cancer-related factors, such as insulin, hypoxia inducible factor-1 (hif-1), p53, nitric oxide (no), and acetylated histone, not only modulate gapdh gene expression but also affect protein functions via common pathways. |
2015-04-10 |
2023-08-13 |
Not clear |
| Li-li Liu, Jiu-li Zhang, Zi-wei Zhang, Hai-dong Yao, Gang Sun, Shi-wen X. Protective roles of selenium on nitric oxide-mediated apoptosis of immune organs induced by cadmium in chickens. Biological trace element research. vol 159. issue 1-3. 2015-01-26. PMID:24839000. |
then, the production of nitric oxide, messenger rna (mrna level), and the activity of inducible nitric oxide synthase, ultrastructural changes, tunel assay, and flow cytometric analysis of apoptosis and bcl-2 and p53 mrna levels in the immune organs were examined. |
2015-01-26 |
2023-08-13 |
chicken |
| Wen-Hsiung Cha. Photodynamic treatment induces an apoptotic pathway involving calcium, nitric oxide, p53, p21-activated kinase 2, and c-Jun N-terminal kinase and inactivates survival signal in human umbilical vein endothelial cells. International journal of molecular sciences. vol 12. issue 2. 2015-01-22. PMID:21541041. |
photodynamic treatment induces an apoptotic pathway involving calcium, nitric oxide, p53, p21-activated kinase 2, and c-jun n-terminal kinase and inactivates survival signal in human umbilical vein endothelial cells. |
2015-01-22 |
2023-08-12 |
human |
| Wen-Hsiung Cha. Photodynamic treatment induces an apoptotic pathway involving calcium, nitric oxide, p53, p21-activated kinase 2, and c-Jun N-terminal kinase and inactivates survival signal in human umbilical vein endothelial cells. International journal of molecular sciences. vol 12. issue 2. 2015-01-22. PMID:21541041. |
in the current study, pretreatment with nitric oxide (no) scavengers inhibited pdt-induced mitochondrial membrane potential (mmp) changes, activation of caspase-9, caspase-3, p21-activated protein kinase 2 (pak2) and c-jun n-terminal kinase (jnk), and gene expression of p53 and p21 involved in apoptotic signaling. |
2015-01-22 |
2023-08-12 |
human |
| Aishath Maharath, Suthat Fucharoen, Dalina I Tanyon. p53 and nitric oxide are involved in cytokine-induced apoptosis in Kasumi-1 and Molt-4 Leukemics cells. Asian Pacific journal of allergy and immunology. vol 32. issue 2. 2014-08-18. PMID:25003726. |
p53 and nitric oxide are involved in cytokine-induced apoptosis in kasumi-1 and molt-4 leukemics cells. |
2014-08-18 |
2023-08-13 |
Not clear |
| Ajay Kumar, Shiva Kant, Sukh Mahendra Sing. Targeting monocarboxylate transporter by α-cyano-4-hydroxycinnamate modulates apoptosis and cisplatin resistance of Colo205 cells: implication of altered cell survival regulation. Apoptosis : an international journal on programmed cell death. vol 18. issue 12. 2014-07-15. PMID:23955790. |
changes in cell survival properties were associated with alterations in lactate efflux, ph homeostasis, expression of glucose transporters, glucose uptake, hif-1α, generation of nitric oxide, expression pattern of some key cell survival regulatory molecules: bcl2, bax, active caspase-3 and p53. |
2014-07-15 |
2023-08-12 |
Not clear |