| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Olivier Guittet, Ali Tebbi, Marie-Hélène Cottet, Françoise Vésin, Michel Lepoivr. Upregulation of the p53R2 ribonucleotide reductase subunit by nitric oxide. Nitric oxide : biology and chemistry. vol 19. issue 2. 2008-09-17. PMID:18474260. |
it has been shown that p53 is activated by nitric oxide, which can damage dna at high concentrations. |
2008-09-17 |
2023-08-12 |
Not clear |
| Hideki Matsumoto, Takeo Ohnish. Indirect influences of radiation on unirradiated cells through irradiated cells. Uchu Seibutsu Kagaku. vol 17. issue 3. 2008-07-16. PMID:14676405. |
previously we reported that the accumulation of inducible nitric oxide (no) synthase (inos) was induced only in human glioblastoma mutant (m) p53 cells by acute irradiation with x-rays, suggesting a suppression of inos induction after acute irradiation with x-rays in wtp53 cells. |
2008-07-16 |
2023-08-12 |
human |
| Wen-Hsiung Chan, Hsin-Jung W. Methylglyoxal and high glucose co-treatment induces apoptosis or necrosis in human umbilical vein endothelial cells. Journal of cellular biochemistry. vol 103. issue 4. 2008-06-20. PMID:17721990. |
pretreatment with nitric oxide (no) scavengers could inhibit 5 microm mg/20 mm glucose-induced cytochrome c release, decrease activation of caspase-9 and caspase-3, and increase the gene expression and protein levels of p53 and p21, which are known to be involved in apoptotic signaling. |
2008-06-20 |
2023-08-12 |
human |
| E L Leung, M Fraser, R R Fiscus, B K Tsan. Cisplatin alters nitric oxide synthase levels in human ovarian cancer cells: involvement in p53 regulation and cisplatin resistance. British journal of cancer. vol 98. issue 11. 2008-06-10. PMID:18506185. |
the present study determines if (1) basal protein levels of nitric oxide (no) synthases (enos, inos, and nnos) are different in cisplatin-sensitive (ov2008) and counterpart cisplatin-resistant (c13(*)) human ovarian cancer cells, (2) cisplatin alters nos levels, (3) no donor causes apoptosis and p53 upregulation, (4) no donor sensitizes c13(*) cells to cisplatin via p53 upregulation (determined by p53 sirna gene-knockdown), and (5) inhibition of endogenous nos alters cisplatin-induced apoptosis. |
2008-06-10 |
2023-08-12 |
human |
| Young-Myeong Kim, Byung-Min Choi, Yong-Seok Kim, Young-Guen Kwon, Melina R Kibbe, Timothy R Billiar, Edith Tzen. Protective effect of p53 in vascular smooth muscle cells against nitric oxide-induced apoptosis is mediated by up-regulation of heme oxygenase-2. BMB reports. vol 41. issue 2. 2008-05-19. PMID:18315954. |
in this study, we investigated the role of p53 in nitric oxide (no)-induced apoptosis in vascular smooth muscle cells (vsmcs). |
2008-05-19 |
2023-08-12 |
Not clear |
| Nadine M Vaninetti, Laurette Geldenhuys, Geoffrey A Porter, Harvey Risch, Pierre Hainaut, Duane L Guernsey, Alan G Casso. Inducible nitric oxide synthase, nitrotyrosine and p53 mutations in the molecular pathogenesis of Barrett's esophagus and esophageal adenocarcinoma. Molecular carcinogenesis. vol 47. issue 4. 2008-04-02. PMID:17849424. |
nitric oxide (no) has been implicated as a potential causative factor for endogenous p53 mutations in gastrointestinal malignancy. |
2008-04-02 |
2023-08-12 |
human |
| Wanda Niedbala, Beilei Cai, Haiying Liu, Nick Pitman, Lynda Chang, Foo Y Lie. Nitric oxide induces CD4+CD25+ Foxp3 regulatory T cells from CD4+CD25 T cells via p53, IL-2, and OX40. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 39. 2007-10-26. PMID:17875988. |
nitric oxide induces cd4+cd25+ foxp3 regulatory t cells from cd4+cd25 t cells via p53, il-2, and ox40. |
2007-10-26 |
2023-08-12 |
mouse |
| Shaun S Klassen, Simon W Rabki. The role of p53 in nitric oxide-induced cardiomyocyte cell death. DNA and cell biology. vol 26. issue 7. 2007-09-06. PMID:17630850. |
the role of p53 in mediating nitric oxide (no)-induced cell death remains uncertain. |
2007-09-06 |
2023-08-12 |
chicken |
| Ritu Gupta, Katie M Dixon, Shivashni S Deo, Carolyn J Holliday, Michael Slater, Gary M Halliday, Vivienne E Reeve, Rebecca S Maso. Photoprotection by 1,25 dihydroxyvitamin D3 is associated with an increase in p53 and a decrease in nitric oxide products. The Journal of investigative dermatology. vol 127. issue 3. 2007-03-05. PMID:17170736. |
photoprotection by 1,25 dihydroxyvitamin d3 is associated with an increase in p53 and a decrease in nitric oxide products. |
2007-03-05 |
2023-08-12 |
mouse |
| Ritu Gupta, Katie M Dixon, Shivashni S Deo, Carolyn J Holliday, Michael Slater, Gary M Halliday, Vivienne E Reeve, Rebecca S Maso. Photoprotection by 1,25 dihydroxyvitamin D3 is associated with an increase in p53 and a decrease in nitric oxide products. The Journal of investigative dermatology. vol 127. issue 3. 2007-03-05. PMID:17170736. |
both the increase in nuclear accumulation of p53 protein and reduced formation of nitric oxide products may contribute to the reduction in tds seen with 1,25(oh)2d3 after uvr. |
2007-03-05 |
2023-08-12 |
mouse |
| Douglas D Thomas, Michael G Espey, Derek A Pociask, Lisa A Ridnour, Sonia Donzelli, David A Win. Asbestos redirects nitric oxide signaling through rapid catalytic conversion to nitrite. Cancer research. vol 66. issue 24. 2007-01-25. PMID:17178853. |
we report here that exposure of human mesothelioma or lung carcinoma cells to nitric oxide (no) in the presence of crocidolite asbestos resulted in a marked decrease in intracellular nitrosation and diminished no-induced posttranslational modifications of tumor-associated proteins (hypoxia-inducible factor-1alpha and p53). |
2007-01-25 |
2023-08-12 |
human |
| Ching-Hsein Chen, Wen-Li Lo, Ya-Chen Liu, Chung-Yi Che. Chemical and cytotoxic constituents from the leaves of Cinnamomum kotoense. Journal of natural products. vol 69. issue 6. 2006-07-31. PMID:16792412. |
treatment with 4 significantly increased intracellular h2o2 and/or peroxide, nitric oxide (no) at 1, 3, and 24 h. our results also showed that compound 4 induced (a) noticeable reduction of mitochondrial transmembrane potential (deltapsi(m)), (b) activation of caspase 3/7, and (c) up-regulation of the p53 expression. |
2006-07-31 |
2023-08-12 |
human |
| Ahmed S Mousa, Shaker A Mous. Anti-angiogenesis efficacy of the garlic ingredient alliin and antioxidants: role of nitric oxide and p53. Nutrition and cancer. vol 53. issue 1. 2006-06-15. PMID:16351512. |
anti-angiogenesis efficacy of the garlic ingredient alliin and antioxidants: role of nitric oxide and p53. |
2006-06-15 |
2023-08-12 |
human |
| H-K Jeon, S-u Choi, N-P Jun. Association of the ERK1/2 and p38 kinase pathways with nitric oxide-induced apoptosis and cell cycle arrest in colon cancer cells. Cell biology and toxicology. vol 21. issue 2. 2006-04-05. PMID:16142585. |
to investigate the mechanism by which nitric oxide (no) induces cell death in colon cancer cells, we compared two types of colon cancer cells with different p53 status: hct116 (p53 wild-type) cells and sw620 (p53-deficient) cells. |
2006-04-05 |
2023-08-12 |
Not clear |
| Shi-fang Zhao, Xiao-yan Tong, Fu-dong Zh. Nitric oxide induces oral squamous cell carcinoma cells apoptosis with p53 accumulation. Oral oncology. vol 41. issue 8. 2006-03-07. PMID:15979383. |
nitric oxide induces oral squamous cell carcinoma cells apoptosis with p53 accumulation. |
2006-03-07 |
2023-08-12 |
Not clear |
| Shi-fang Zhao, Xiao-yan Tong, Fu-dong Zh. Nitric oxide induces oral squamous cell carcinoma cells apoptosis with p53 accumulation. Oral oncology. vol 41. issue 8. 2006-03-07. PMID:15979383. |
exogenous nitric oxide had an inhibitory effect on tca8113 cells proliferation in a dose and time-dependent manners and possibly via p53 dependent apoptosis pathway. |
2006-03-07 |
2023-08-12 |
Not clear |
| P A Brenna. Nitric oxide induces oral squamous cell carcinoma cell apoptosis with p53 accumulation [Oral Oncology 41 (8) (2005) 785-790]. Oral oncology. vol 41. issue 8. 2006-03-07. PMID:16054425. |
nitric oxide induces oral squamous cell carcinoma cell apoptosis with p53 accumulation [oral oncology 41 (8) (2005) 785-790]. |
2006-03-07 |
2023-08-12 |
Not clear |
| Lee J Martin, Kevin Chen, Zhiping Li. Adult motor neuron apoptosis is mediated by nitric oxide and Fas death receptor linked by DNA damage and p53 activation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 27. 2006-02-28. PMID:16000635. |
adult motor neuron apoptosis is mediated by nitric oxide and fas death receptor linked by dna damage and p53 activation. |
2006-02-28 |
2023-08-12 |
mouse |
| H Seda Vatansever, Selman Lacin, M Kemal Ozbilgi. Changed Bcl:Bax ratio in endometrium of patients with unexplained infertility. Acta histochemica. vol 107. issue 5. 2006-02-03. PMID:16139338. |
in this study, we investigated the role of spontaneous apoptosis, which is regulated by death regulatory genes, such as bcl-2, bax, p53, and isoenzymes of nitric oxide synthases; enos and inos during the implantation window in women with unexplained infertility. |
2006-02-03 |
2023-08-12 |
Not clear |
| Jing Zhao, Junying Miao, Baoxiang Zhao, Shangli Zhan. Upregulating of Fas, integrin beta4 and P53 and depressing of PC-PLC activity and ROS level in VEC apoptosis by safrole oxide. FEBS letters. vol 579. issue 25. 2005-12-19. PMID:16225864. |
in this study, to investigate its mechanism to induce apoptosis in vecs, the activities of nitric oxide synthetase and phosphatidylcholine specific phospholipase c, the level of reactive oxygen species and the expressions of fas, integrin beta4 and p53 were analyzed. |
2005-12-19 |
2023-08-12 |
Not clear |