| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hayley Chan, Ketaki P Bhide, Aditya Vaidyam, Victoria Hedrick, Tiago Jose Paschoal Sobreira, Thomas G Sors, Ryan W Grant, Uma K Arya. Proteomic Analysis of 3T3-L1 Adipocytes Treated with Insulin and TNF-α. Proteomes. vol 7. issue 4. 2021-02-18. PMID:31635166. |
to better understand the roles played by insulin and tnf-α in insulin resistance, we performed proteomic analysis of differentiated 3t3-l1 adipocytes treated with insulin (ins), tnf-α (tnf), and both (ins + tnf). |
2021-02-18 |
2023-08-13 |
Not clear |
| Shweta A More, Akshay S Patil, Nikhil S Sakle, Santosh N Mokal. Network analysis and molecular mapping for SARS-CoV-2 to reveal drug targets and repurposing of clinically developed drugs. Virology. vol 555. 2021-02-15. PMID:33421743. |
kegg pathway analysis involves multiple pathways (p < 0.05), including foxo, gnrh, erbb, neurotrophin, toll-like receptor, il-17, tnf, insulin, hif-1, jak-stat, estrogen, nf-kappa, chemokine, vegf, and thyroid hormone signaling pathway in sars-cov-2. |
2021-02-15 |
2023-08-13 |
Not clear |
| Yaser Jafari Khataylou, Somayeh Ahmadiafshar, Reza Rezaei, Saeid Parsamanesh, Golbahar Hossein. Curcumin Ameliorate Diabetes type 1 Complications through Decreasing Pro-inflammatory Cytokines in C57BL/6 Mice. Iranian journal of allergy, asthma, and immunology. vol 19. issue S1. 2021-02-08. PMID:32534511. |
the present study examines changes in serum levels of interleukin (il)-6, il-17, il-10, tumor necrosis factor (tnf)-α, interferon (ifn)-γ, c-peptide, insulin as well as fasting blood sugar (fbs) in control, diabetic and diabetic treated with curcumin groups. |
2021-02-08 |
2023-08-13 |
mouse |
| R Kasimanickam, V Kasimanickam, J P Kastelic, K Ramse. Metabolic biomarkers, body condition, uterine inflammation and response to superovulation in lactating Holstein cows. Theriogenology. vol 146. 2021-01-28. PMID:32062150. |
the objective was to determine associations between response to superovulation and body condition, subclinical endometritis and circulating metabolic biomarkers [adiponectin, leptin, insulin, igf1, tumor necrosis factor (tnf) α, interleukin (il) 1β, il6, and urea] in lactating dairy cows. |
2021-01-28 |
2023-08-13 |
Not clear |
| Kun Dong, Qiuchen Zhao, Yaqiang Xue, Yaxun Wei, Yi Zhang, Yan Yan. TCTP participates in hepatic metabolism by regulating gene expression involved in insulin resistance. Gene. vol 768. 2021-01-25. PMID:33122078. |
knock-down of tctp led to 287 differentially expressed genes (degs) that were highly associated with cellular apoptosis and signal response, tnf and nf-κb signaling pathways, glycolysis/gluconeogenesis, insulin resistance, foxo and insulin signaling pathways, adipocytokine and ampk signaling pathways. |
2021-01-25 |
2023-08-13 |
mouse |
| Jisheng Wang, Xuefeng Gong, Sheng Deng, Fanchao Meng, Hengheng Dai, Binghao Bao, Junlong Feng, Haisong Li, Bin Wan. Effect of Asthma on Erectile Dysfunction in Rats as Determined by Biological Network Analysis. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2021-01-04. PMID:33341820. |
real-time quantitative polymerase chain reaction (rt-qpcr) and western blotting were used to determine the expression levels of insulin (ins), interleukin 6 (il6), albumin (alb), tumor necrosis factor (tnf), and vascular endothelial growth factor a (vegfa) at both the protein and messenger ribonucleic acid (mrna) levels. |
2021-01-04 |
2023-08-13 |
rat |
| Jose Antonio Januario Neves, Mozânia Reis De Matos, Theresa Ramalho, Daniele Pereira Santos-Bezerra, Cristiane Das Graças Dias Cavalcante, Renata D' Alpino Peixoto, Márcia Silva Queiroz, Sonia Jancar, Maria Lucia Correa-Giannell. Increased leukotriene B4 plasma concentration in type 2 diabetes individuals with cardiovascular autonomic neuropathy. Diabetology & metabolic syndrome. vol 12. issue 1. 2020-12-12. PMID:33292560. |
this cross-sectional study evaluated plasma concentration of ltb4 and of other inflammatory mediators, namely, tumor necrosis factor (tnf), interleukin (il)1b, and il10 in individuals with type 2 diabetes (t2d) and different degrees of can, and correlated these inflammatory mediators with the degree of glycemic control and with a surrogate marker of insulin resistance. |
2020-12-12 |
2023-08-13 |
Not clear |
| Y G G Mizubuti, E L M Vieira, T A Silva, M O d'Alessandro, S V Generoso, A L Teixeira, A S Lima, M I T D Correi. Comparing the effects of whey and casein supplementation on nutritional status and immune parameters in patients with chronic liver disease: a randomised double-blind controlled trial. The British journal of nutrition. 2020-10-06. PMID:32807252. |
no differences were observed in body composition, muscle functionality, most plasma cytokines (tnf, il-6, il-1β and interferon-γ), immunomodulatory proteins (stnfr1, stnfr2, brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor) or immunomodulatory hormones (adiponectin, insulin and leptin) after supplementation in the wp groups at the two assessed moments. |
2020-10-06 |
2023-08-13 |
Not clear |
| Amal Jamil Fatani, Salim Salih Al-Rejaie, Hatem Mustafa Abuohashish, Abdullah Al-Assaf, Mihir Yogeshkumar Parmar, Mohammad Shamsul Ola, Mohammed Mahboobuddin Ahme. Neuroprotective effects of Experimental and therapeutic medicine. vol 9. issue 5. 2020-10-01. PMID:26136876. |
in addition, the serum levels of glucose, insulin and proinflammatory cytokines, including tumor necrosis factor (tnf)-α, interleukin (il)-1β and il-6, were determined. |
2020-10-01 |
2023-08-13 |
rat |
| Long Zhou, Lilin Wang, Baocheng Yang, Jinfeng Zeng, Qingguo Zhang, Hongyi Lei, Shiyuan X. Protective effect of pretreatment with propofol against tumor necrosis factor-α-induced hepatic insulin resistance. Experimental and therapeutic medicine. vol 10. issue 1. 2020-10-01. PMID:26170951. |
notably, pretreatment with propofol in tumor necrosis factor (tnf)-α-induced primary mouse hepatocytes with insulin resistance was demonstrated to alleviate the inhibitory effects of tnf-α on the pi3k/akt/gsk-3β signaling pathway and glycogen synthesis. |
2020-10-01 |
2023-08-13 |
mouse |
| Xin Li, Li Jiang, Miao Yang, Yu-Wen Wu, Jia-Zhong Su. Impact of weight cycling on CTRP3 expression, adipose tissue inflammation and insulin sensitivity in C57BL/6J mice. Experimental and therapeutic medicine. vol 16. issue 3. 2020-10-01. PMID:30186439. |
impacts of weight cycling on c1q/tumor necrosis factor (tnf)-related protein-3 (ctrp3) expression, adipose tissue inflammation and insulin sensitivity in c57bl/6j mice were evaluated in the current study. |
2020-10-01 |
2023-08-13 |
mouse |
| Inger Sundström-Poromaa, Win Pa Pa Thu, Michael S Kramer, Susan Logan, Jane A Cauley, Eu-Leong Yon. Risk factors for insulin resistance in midlife Singaporean women. Maturitas. vol 137. 2020-09-24. PMID:32498937. |
to understand the extent to which risk factors for insulin resistance are mediated by body mass index (bmi), visceral adipose tissue (vat), physical activity and performance, and the inflammatory markers interleukin (il)-6, tumor necrosis factor (tnf)- α, and high-sensitivity c-reactive protein (hs-crp). |
2020-09-24 |
2023-08-13 |
Not clear |
| Cai-Jing He, Jing Wang, Shuai Liang, Jun Li, Xian-Ju Huan. [Study on hepatoprotective mechanisms of Veratrilla baillonii based on network pharmacology]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 45. issue 8. 2020-09-17. PMID:32489062. |
kegg enrichment analysis showed that pi3 k-akt signaling pathway, hif-1 signaling pathway, mapk signaling pathway, insulin signaling pathway, tnf signaling pathway and some cancer-related pathways were more enriched. |
2020-09-17 |
2023-08-13 |
Not clear |
| Nagat Younan, Samah Elattar, Mira Farouk, Laila Rashed, Suzanne Estapha. Dipeptidyl peptidase-4 inhibitors and aerobic exercise synergistically protect against liver injury in ovariectomized rats. Physiological reports. vol 7. issue 17. 2020-08-18. PMID:31496048. |
after 6 weeks, alanine aminotransferase (alt), glucose, insulin, homa ir (homeostatic model assessment for insulin resistance), ffa (free fatty acids), tumor necrosis factor alpha (tnf α), il6, il1b levels were measured in blood. |
2020-08-18 |
2023-08-13 |
rat |
| Yingchun Hu, Lingxia Cheng, Wu Zhong, Muhu Chen, Qian Zhan. Bioinformatics Analysis of Gene Expression Profiles for Risk Prediction in Patients with Septic Shock. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-06-03. PMID:31838482. |
kyoto encyclopedia of genes and genomes (kegg) pathway analysis identified significantly enriched degs in four signaling pathways, mapk, tnf, hif-1, and insulin. |
2020-06-03 |
2023-08-13 |
human |
| Richa Bhatnager, Jitesh Jalthuria, Ravinder Sehrawat, Smiti Nanda, Amita S Dan. Evaluating the association of TNF α promoter haplotype with its serum levels and the risk of PCOS: A case control study. Cytokine. vol 114. 2020-03-26. PMID:30442458. |
tnf α, pro-inflammatory cytokine is associated with obesity, insulin resistance and hyperandrogenism, therefore in present study we tried to find the association between tnf α promoter polymorphisms, tnf α levels and the risk of pcos. |
2020-03-26 |
2023-08-13 |
Not clear |
| J L Martin-Rodriguez, J Gonzalez-Cantero, A Gonzalez-Cantero, L Martí-Bonmatí, Á Alberich-Bayarri, T Gonzalez-Cejudo, J L Gonzalez-Calvi. Insulin resistance and NAFLD: Relationship with intrahepatic iron and serum TNF-α using 1H MR spectroscopy and MRI. Diabetes & metabolism. vol 45. issue 5. 2020-02-27. PMID:30660761. |
the association of non-alcoholic fatty liver disease (nafld) with insulin resistance (ir) is well established, yet little is known of their possible relationship with intrahepatic iron and serum tumour necrosis factor (tnf)-α concentrations in adults without diabetes. |
2020-02-27 |
2023-08-13 |
Not clear |
| Eyal Seroussi, Martin Knytl, Frédérique Pitel, Daniel Elleder, Vladimir Krylov, Sophie Leroux, Mireille Morisson, Sara Yosefi, Shoval Miyara, Saibaba Ganesan, Mark Ruzal, Leif Andersson, Miriam Friedman-Eina. Avian Expression Patterns and Genomic Mapping Implicate Leptin in Digestion and TNF in Immunity, Suggesting That Their Interacting Adipokine Role Has Been Acquired Only in Mammals International journal of molecular sciences. vol 20. issue 18. 2020-01-30. PMID:31514326. |
avian expression patterns and genomic mapping implicate leptin in digestion and tnf in immunity, suggesting that their interacting adipokine role has been acquired only in mammals in mammals, leptin and tumor-necrosis factor (tnf) are prominent interacting adipokines mediating appetite control and insulin sensitivity. |
2020-01-30 |
2023-08-13 |
Not clear |
| Taeseung Lee, Subin Yun, Ji Hoon Jeong, Tae Woo Jun. Asprosin impairs insulin secretion in response to glucose and viability through TLR4/JNK-mediated inflammation. Molecular and cellular endocrinology. vol 486. 2020-01-17. PMID:30853600. |
treatment of min6 cells and human primary islets with palmitate increased phosphorylation of the inflammatory marker nuclear factor-kappa b (nfκb) and the release of pro-inflammatory cytokines including tnf and mcp-1 and decreased glucose-stimulated insulin secretion and cell viability. |
2020-01-17 |
2023-08-13 |
mouse |
| A K Das, S Kalra, M Tiwaskar, S Bajaj, K Seshadri, S Chowdhury, R Sahay, S Indurkar, A G Unnikrishnan, U Phadke, A Pareek, I Purkai. Expert Group Consensus Opinion: Role of Anti-inflammatory Agents in the Management of Type-2 Diabetes (T2D). The Journal of the Association of Physicians of India. vol 67. issue 12. 2019-12-23. PMID:31801334. |
other selective inhibitors like anakinra (il-1 receptor antagonist) and etanercept (tnf inhibitor) too have yielded modest effects on glycemic parameters and insulin sensitivity. |
2019-12-23 |
2023-08-13 |
human |