| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jian Huang, John M Shelton, James A Richardson, Kristine E Kamm, James T Stul. Myosin regulatory light chain phosphorylation attenuates cardiac hypertrophy. The Journal of biological chemistry vol 283 issue 28 2008 18474588 |
hearts and cardiomyocytes from wt animals subjected to voluntary running exercise and isoproterenol treatment showed hypertrophic cardiac responses, but the responses for tg mice were attenuated. |
2008-08-28 |
2023-01-24 |
mouse |
| Mario Patrizio, Marco Musumeci, Tonino Stati, Katia Fecchi, Elisabetta Mattei, Liviana Catalano, Giuseppe Maran. Propranolol promotes Egr1 gene expression in cardiomyocytes via beta-adrenoceptors. European journal of pharmacology vol 587 issue 1-3 2008 18485346 |
remarkably, isoproterenol administration was associated with the development of cardiac hypertrophy, whereas propranolol-treated mice showed a completely normal cardiac morphology. |
2008-08-25 |
2023-01-24 |
mouse |
| Laurent Monassier, Marc-Andr\\xc3\\xa9 Laplante, Fabrice Jaffr\\xc3\\xa9, Pascal Bousquet, Luc Maroteaux, Jacques de Champlai. Serotonin 5-HT(2B) receptor blockade prevents reactive oxygen species-induced cardiac hypertrophy in mice. Hypertension (Dallas, Tex. : 1979) vol 52 issue 2 2008 18591460 |
therefore, we measured the effects of serotonergic 5-ht(2b) receptor blockade on left-ventricular superoxide anion generation in 2 established pharmacological models of cardiac hypertrophy, ie, angiotensin ii and isoproterenol infusions in mice. |
2008-08-22 |
2023-01-25 |
mouse |
| Laurent Monassier, Marc-Andr\\xc3\\xa9 Laplante, Fabrice Jaffr\\xc3\\xa9, Pascal Bousquet, Luc Maroteaux, Jacques de Champlai. Serotonin 5-HT(2B) receptor blockade prevents reactive oxygen species-induced cardiac hypertrophy in mice. Hypertension (Dallas, Tex. : 1979) vol 52 issue 2 2008 18591460 |
similarly, infusion for 5 days of isoproterenol increased left-ventricular nad(p)h oxidase activity (+48%) and cardiac hypertrophy (+31%) that were prevented by the 5-ht(2b) receptor blockade. |
2008-08-22 |
2023-01-25 |
mouse |
| Lick Pui Lai, Jane Mitchel. Beta2-adrenergic receptors expressed on murine chondrocytes stimulate cellular growth and inhibit the expression of Indian hedgehog and collagen type X. Journal of cellular biochemistry vol 104 issue 2 2008 18059015 |
the cellular expression of two markers of chondrocyte differentiation, indian hedgehog, expressed in pre-hypertrophic cells and collagen type x, expressed in hypertrophic chondrocytes, were both significantly inhibited after incubation with isoproterenol. |
2008-07-08 |
2023-01-24 |
mouse |
| Eduardo Manuel Escudero, Oscar Andr\\xc3\\xa9s Pinill. [Paradigms and paradoxes of left ventricular hypertrophy: from the research laboratory to the clinical consultation]. Archivos de cardiologia de Mexico vol 77 issue 3 2008 18050937 |
after analyzed left ventricular functional and structural changes in rats induced by arterial hypertension, banding of aortic root, isoproterenol administration, or myocardial infarction, as well as in patients with arterial hypertension, aortic stenosis, or hypertrophic miocardiopathy, we found a maladaptive response considered as pathological hypertrophy. |
2008-04-29 |
2023-01-24 |
rat |
| William E Stansfield, Ru-Hang Tang, Nancy C Moss, Albert S Baldwin, Monte S Willis, Craig H Selzma. Proteasome inhibition promotes regression of left ventricular hypertrophy. American journal of physiology. Heart and circulatory physiology vol 294 issue 2 2008 18032525 |
a murine model of reversible hypertrophy was employed by administering isoproterenol (iso) subcutaneously for 7-14 days. |
2008-03-31 |
2023-01-24 |
Not clear |
| Ahmad Elesber, Rick A Nishimura, Charanjit S Rihal, Steve R Ommen, Hartzell V Schaff, David R Holme. Utility of isoproterenol to provoke outflow tract gradients in patients with hypertrophic cardiomyopathy. The American journal of cardiology vol 101 issue 4 2008 18312769 |
utility of isoproterenol to provoke outflow tract gradients in patients with hypertrophic cardiomyopathy. |
2008-03-28 |
2023-01-24 |
Not clear |
| Yong-Gang Zhang, Yu-Guang Li, Bao-Guo Liu, Rui-Hong Wei, Dong-Ming Wang, Xue-Rui Tan, Ding-Fang Bu, Yong-Zheng Pang, Chao-Shu Tan. Urotensin II accelerates cardiac fibrosis and hypertrophy of rats induced by isoproterenol. Acta pharmacologica Sinica vol 28 issue 1 2008 17184580 |
urotensin ii accelerates cardiac fibrosis and hypertrophy of rats induced by isoproterenol. |
2008-03-17 |
2023-01-24 |
rat |
| Yong-Gang Zhang, Yu-Guang Li, Bao-Guo Liu, Rui-Hong Wei, Dong-Ming Wang, Xue-Rui Tan, Ding-Fang Bu, Yong-Zheng Pang, Chao-Shu Tan. Urotensin II accelerates cardiac fibrosis and hypertrophy of rats induced by isoproterenol. Acta pharmacologica Sinica vol 28 issue 1 2008 17184580 |
to study whether urotensin ii (uii), a potent vasoconstrictive peptide, is involved in the development of cardiac hypertrophy and fibrogenesis of rats induced by isoproterenol (iso). |
2008-03-17 |
2023-01-24 |
rat |
| Anderson J Ferreira, Thauana L Oliveira, Maria Carolina M Castro, Alvair P Almeida, Carlos H Castro, Marcelo V Caliari, Elisandra Gava, Gregory T Kitten, Robson A S Santo. Isoproterenol-induced impairment of heart function and remodeling are attenuated by the nonpeptide angiotensin-(1-7) analogue AVE 0991. Life sciences vol 81 issue 11 2007 17825326 |
heart hypertrophy and heart dysfunction were induced by isoproterenol (iso) (2 mg/kg i.p./day for 7 days) in male wistar rats. |
2007-10-26 |
2023-01-24 |
rat |
| Coskun Ulucan, Xu Wang, Erdene Baljinnyam, Yunzhe Bai, Satoshi Okumura, Motohiko Sato, Susumu Minamisawa, Shinichi Hirotani, Yoshihiro Ishikaw. Developmental changes in gene expression of Epac and its upregulation in myocardial hypertrophy. American journal of physiology. Heart and circulatory physiology vol 293 issue 3 2007 17557924 |
in addition to developmental changes, we found that epac gene expression was upregulated in myocardial hypertrophy induced by chronic isoproterenol infusion or pressure overload by transverse aortic banding. |
2007-10-19 |
2023-01-24 |
Not clear |
| R Kumar, S Sharm. Isoproterenol hydrochloride augments collagen proliferation and ATPase activity in mice soleus and EDL muscles. Acta physiologica Hungarica vol 94 issue 3 2007 17853774 |
isoproterenol resulted in significant increase in muscle weight to whole body weight ratio with no increase in hypertrophy index in soleus muscle. |
2007-10-04 |
2023-01-24 |
mouse |
| Oleg Osadchii, Gavin Norton, Dawn Deftereos, Angela Woodiwis. Rat strain-related differences in myocardial adrenergic tone and the impact on cardiac fibrosis, adrenergic responsiveness and myocardial structure and function. Pharmacological research vol 55 issue 4 2007 17257851 |
however, increases in myocardial noradrenaline release in sd rats did not translate into enhanced myocardial fibrosis, cardiac hypertrophy or remodeling, changes in basal ventricular systolic and diastolic function, or to down-regulation of inotropic responses to the beta-adrenoreceptor agonists, noradrenaline, isoproterenol and dobutamine. |
2007-08-29 |
2023-01-24 |
rat |
| Yutaka Kitagawa, Yamato Tamura, Juichiro Shimizu, Chikako Nakajima-Takenaka, Shigeki Taniguchi, Shinichi Uesato, Miyako Takak. Effects of a novel histone deacetylase inhibitor, N-(2-aminophenyl) benzamide, on a reversible hypertrophy induced by isoproterenol in in situ rat hearts. Journal of pharmacological sciences vol 104 issue 2 2007 17558183 |
effects of a novel histone deacetylase inhibitor, n-(2-aminophenyl) benzamide, on a reversible hypertrophy induced by isoproterenol in in situ rat hearts. |
2007-08-23 |
2023-01-24 |
rat |
| Dan Shan, Hongxin Wang, Yuhong Su, Yang Jing, Tak Ming Won. kappa-opioid receptor stimulation inhibits cardiac hypertrophy induced by beta1-adrenoceptor stimulation in the rat. European journal of pharmacology vol 555 issue 2-3 2007 17126321 |
to test the hypothesis that kappa-opioid receptor stimulation inhibits cardiac hypertrophy induced by beta1-adrenoceptor stimulation, we determined the effects of trans-(+/-)-3,4-dichloro-n-methyl-n-[2-(1-pyrrolidinyl)-cyclohexyl]-benzeneacetamide methanesulfonate salt (u50,488h), a selective kappa-opioid receptor agonist, on cardiac hypertrophy induced by isoprenaline, a selective beta-adrenoceptor agonist, in neonatal ventricular myocytes upon blockade of beta2-adrenoceptor. |
2007-04-04 |
2023-01-24 |
rat |
| Eric J Jaehnig, Analeah B Heidt, Stephanie B Greene, Ivo Cornelissen, Brian L Blac. Increased susceptibility to isoproterenol-induced cardiac hypertrophy and impaired weight gain in mice lacking the histidine-rich calcium-binding protein. Molecular and cellular biology vol 26 issue 24 2007 17030629 |
in addition, hrc null mice displayed a significantly exaggerated response to the induction of cardiac hypertrophy by isoproterenol compared to their wild-type littermates. |
2007-01-24 |
2023-01-24 |
mouse |
| Sung-Young Shin, Sang-Mok Choo, Dongsan Kim, Song Joon Baek, Olaf Wolkenhauer, Kwang-Hyun Ch. Switching feedback mechanisms realize the dual role of MCIP in the regulation of calcineurin activity. FEBS letters vol 580 issue 25 2006 17046757 |
however, it has been shown that mcip facilitates or permits the hypertrophic response under some stress conditions such as isoproterenol infusion or pressure overload by transverse aortic constriction. |
2006-12-20 |
2023-01-24 |
Not clear |
| Geum Shil Hwang, Kwang-Seok Oh, Hyun-Na Koo, Ho Won Seo, Kwan-Hee You, Byung Ho Le. Effects of KR-31378, a novel ATP-sensitive potassium channel activator, on hypertrophy of H9c2 cells and on cardiac dysfunction in rats with congestive heart failure. European journal of pharmacology vol 540 issue 1-3 2006 16729997 |
in rat heart-derived h9c2 cells treated with hypertrophic agonists, such as angiotensin ii, phenylephrine, isoproterenol, and urotensin ii, cell size was significantly increased by 27-47%. |
2006-12-11 |
2023-01-24 |
rat |
| Nari Kim, Hyunju Kim, Jae Boum Youm, Won Sun Park, Mohamad Warda, Jae-Hong Ko, Jin Ha. Site specific differential activation of ras/raf/ERK signaling in rabbit isoproterenol-induced left ventricular hypertrophy. Biochimica et biophysica acta vol 1763 issue 10 2006 16987560 |
to understand better the mediating role of ras/raf/erk signaling pathway in development of cardiac hypertrophy and cerebrovascular events in vivo, the molecular mechanism of the pathway in heart and cerebral arteries after isoproterenol (iso) induced beta-adrenergic receptor (betaar) stimulation was examined in rabbit as animal model. |
2006-12-06 |
2023-01-24 |
rabbit |