| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L C Heather, A F Catchpole, D J Stuckey, M A Cole, C A Carr, K Clark. Isoproterenol induces in vivo functional and metabolic abnormalities: similar to those found in the infarcted rat heart. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 60. issue 3. 2010-03-30. PMID:19826179. |
in conclusion, isoproterenol infusion impaired in vivo cardiac function, induced hypertrophy, and decreased both fatty acid and glucose metabolism, changes similar in direction and magnitude to those found in the rat heart following moderate severity myocardial infarction. |
2010-03-30 |
2023-08-12 |
rat |
| Miguel Copaja Soto, Rodrigo Valenzuela, Adiela Saldaña, María Paz Ocaranza, Jorge E Jalil, Carlos Vio, Paul Lijnen, Gamaliel E Ordenes, Raul Vivar Sanchez, Sergio Lavandero, Guillermo Díaz-Aray. Early expression of monocyte chemoattractant protein-1 correlates with the onset of isoproterenol-induced cardiac fibrosis in rats with distinct angiotensin-converting enzyme polymorphism. Journal of the renin-angiotensin-aldosterone system : JRAAS. vol 9. issue 3. 2010-01-13. PMID:18957386. |
isoproterenol treatment of brown norway and lewis rats (high and low plasma angiotensin-i-converting enzyme activity, respectively) results in similar cardiac hypertrophy but higher cardiac fibrosis in brown norway rats. |
2010-01-13 |
2023-08-12 |
rat |
| Hiroyuki Nakayama, Ilona Bodi, Robert N Correll, Xiongwen Chen, John Lorenz, Steven R Houser, Jeffrey Robbins, Arnold Schwartz, Jeffery D Molkenti. alpha1G-dependent T-type Ca2+ current antagonizes cardiac hypertrophy through a NOS3-dependent mechanism in mice. The Journal of clinical investigation. vol 119. issue 12. 2010-01-11. PMID:19920353. |
conversely, alpha1g-/- mice displayed enhanced hypertrophic responses following pressure overload or isoproterenol infusion. |
2010-01-11 |
2023-08-12 |
mouse |
| Beshay N M Zordoky, Mona E Aboutabl, Ayman O S El-Kad. Modulation of cytochrome P450 gene expression and arachidonic acid metabolism during isoproterenol-induced cardiac hypertrophy in rats. Drug metabolism and disposition: the biological fate of chemicals. vol 36. issue 11. 2009-11-13. PMID:18725507. |
our results show that isoproterenol treatment significantly increased the heart/body weight ratio and the hypertrophic markers. |
2009-11-13 |
2023-08-12 |
rat |
| Juliano L Sartoretto, Benjamin Y Jin, Michael Bauer, Frank B Gertler, Ronglih Liao, Thomas Miche. Regulation of VASP phosphorylation in cardiac myocytes: differential regulation by cyclic nucleotides and modulation of protein expression in diabetic and hypertrophic heart. American journal of physiology. Heart and circulatory physiology. vol 297. issue 5. 2009-11-12. PMID:19734360. |
moreover, there is further increase in vasp phosphorylation in cells isolated from hypertrophic hearts following isoproterenol treatment. |
2009-11-12 |
2023-08-12 |
mouse |
| Wesley W Brooks, Chester H Conra. Isoproterenol-induced myocardial injury and diastolic dysfunction in mice: structural and functional correlates. Comparative medicine. vol 59. issue 4. 2009-11-09. PMID:19712573. |
isoproterenol induced marked endocardial injury, associated with hypertrophy of surviving myocytes, and an increase in myocardial fibrosis (collagen types i and iii according to picrosirius red microscopy). |
2009-11-09 |
2023-08-12 |
mouse |
| Zhiqiang Lin, Iram Murtaza, Kun Wang, Jianqin Jiao, Jie Gao, Pei-Feng L. miR-23a functions downstream of NFATc3 to regulate cardiac hypertrophy. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 29. 2009-08-25. PMID:19574461. |
the results showed that mir-23a expression was up-regulated upon treatment with the hypertrophic stimuli including isoproterenol and aldosterone. |
2009-08-25 |
2023-08-12 |
Not clear |
| Wen Yin, Peng Zhang, Jing Hui Huang, Quan Yu Zhang, Rong Fan, Juan Li, Jing Jun Zhou, Yu Zhen Hu, Hai Tao Guo, Shu Miao Zhang, Yue Min Wang, Alan David Kaye, Chun Hu Gu, Jin Cheng Liu, Liang Cheng, Qin Cui, Ding Hua Yi, Jian Ming Pe. Stimulation of kappa-opioid receptor reduces isoprenaline-induced cardiac hypertrophy and fibrosis. European journal of pharmacology. vol 607. issue 1-3. 2009-07-07. PMID:19233160. |
cardiac hypertrophy and fibrosis were developed by intraperitoneal administration of isoprenaline (ip. |
2009-07-07 |
2023-08-12 |
rat |
| Wen Yin, Peng Zhang, Jing Hui Huang, Quan Yu Zhang, Rong Fan, Juan Li, Jing Jun Zhou, Yu Zhen Hu, Hai Tao Guo, Shu Miao Zhang, Yue Min Wang, Alan David Kaye, Chun Hu Gu, Jin Cheng Liu, Liang Cheng, Qin Cui, Ding Hua Yi, Jian Ming Pe. Stimulation of kappa-opioid receptor reduces isoprenaline-induced cardiac hypertrophy and fibrosis. European journal of pharmacology. vol 607. issue 1-3. 2009-07-07. PMID:19233160. |
increases in heart weight, heart-to-body ratio, diameter of cardiomyocytes, and morphological hypertrophic alterations induced by isoprenaline were significantly attenuated by u50,488h(i.p. |
2009-07-07 |
2023-08-12 |
rat |
| Bernard Abrenica, Mohamed AlShaaban, Michael P Czubry. The A-kinase anchor protein AKAP121 is a negative regulator of cardiomyocyte hypertrophy. Journal of molecular and cellular cardiology. vol 46. issue 5. 2009-06-17. PMID:19358331. |
we also demonstrate that over-expression of akap121 in cardiac myocytes reduces basal cell size, and blocks hypertrophy induced by isoproterenol, indicating that akap121 negatively regulates the hypertrophic process. |
2009-06-17 |
2023-08-12 |
rat |
| Kyuho Jeong, Hayeong Kwon, Chanhee Min, Yunbae Pa. Modulation of the caveolin-3 localization to caveolae and STAT3 to mitochondria by catecholamine-induced cardiac hypertrophy in H9c2 cardiomyoblasts. Experimental & molecular medicine. vol 41. issue 4. 2009-06-02. PMID:19299911. |
we investigated the effect of phenylephrine (pe)- and isoproterenol (iso)-induced cardiac hypertrophy on subcellular localization and expression of caveolin-3 and stat3 in h9c2 cardiomyoblast cells. |
2009-06-02 |
2023-08-12 |
Not clear |
| M Anderson, D Moore, Df Larso. Comparison of isoproterenol and dobutamine in the induction of cardiac hypertrophy and fibrosis. Perfusion. vol 23. issue 4. 2009-05-19. PMID:19181756. |
comparison of isoproterenol and dobutamine in the induction of cardiac hypertrophy and fibrosis. |
2009-05-19 |
2023-08-12 |
mouse |
| M Anderson, D Moore, Df Larso. Comparison of isoproterenol and dobutamine in the induction of cardiac hypertrophy and fibrosis. Perfusion. vol 23. issue 4. 2009-05-19. PMID:19181756. |
isoproterenol (iso) was a clinical therapeutic that is now used as a research means for the induction of cardiac hypertrophy. |
2009-05-19 |
2023-08-12 |
mouse |
| A C Issy, C A da Silva, F S Guimarães, E A Del Be. Different role of isoproterenol and NOS inhibitors on salivary ducts of rats. Micron (Oxford, England : 1993). vol 40. issue 3. 2009-04-30. PMID:19167231. |
chronic treatment with isoproterenol, a beta receptor agonist, stimulates the release of no from acinar cells and induces salivary gland hypertrophy. |
2009-04-30 |
2023-08-12 |
rat |
| Daniel R Higazi, Claire J Fearnley, Faye M Drawnel, Amarnath Talasila, Elaine M Corps, Oliver Ritter, Fraser McDonald, Katsuhiko Mikoshiba, Martin D Bootman, H Llewelyn Roderic. Endothelin-1-stimulated InsP3-induced Ca2+ release is a nexus for hypertrophic signaling in cardiac myocytes. Molecular cell. vol 33. issue 4. 2009-04-06. PMID:19250908. |
moreover, we found that activation of the cna/nfat pathway and hypertrophy by isoproterenol and bayk8644, which enhance global ca(2+) fluxes, was also dependent on iicr and nuclear ca(2+) elevations. |
2009-04-06 |
2023-08-12 |
Not clear |
| Yun-He Liu, Martin D'Ambrosio, Tang-dong Liao, Hongmei Peng, Nour-Eddine Rhaleb, Umesh Sharma, Sabine André, Hans-J Gabius, Oscar A Carreter. N-acetyl-seryl-aspartyl-lysyl-proline prevents cardiac remodeling and dysfunction induced by galectin-3, a mammalian adhesion/growth-regulatory lectin. American journal of physiology. Heart and circulatory physiology. vol 296. issue 2. 2009-03-12. PMID:19098114. |
we found that, in the left ventricle, gal-3 1) enhanced macrophage and mast cell infiltration, increased cardiac interstitial and perivascular fibrosis, and causes cardiac hypertrophy; 2) increased tgf-beta expression and smad3 phosphorylation; and 3) decreased negative change in pressure over time response to isoproterenol challenge, ratio of early left ventricular filling phase to atrial contraction phase, and left ventricular ejection fraction. |
2009-03-12 |
2023-08-12 |
rat |
| Jun Cai, Fang-Fang Yi, Long Yang, Di-Fei Shen, Qinling Yang, Ankang Li, Asish K Ghosh, Zhou-Yan Bian, Ling Yan, Qi-Zhu Tang, Hongliang Li, Xin-Chun Yan. Targeted expression of receptor-associated late transducer inhibits maladaptive hypertrophy via blocking epidermal growth factor receptor signaling. Hypertension (Dallas, Tex. : 1979). vol 53. issue 3. 2009-03-09. PMID:19204184. |
we investigated the effect of cardiac overexpression of rat ralt on cardiac hypertrophy induced by angiotensin ii and isoproterenol in ralt transgenic mice and wild-type littermates. |
2009-03-09 |
2023-08-12 |
mouse |
| T Yar, M El-Hariri, M N El-Bahai, A O Bamos. Effects of Nigella sativa supplementation for one month on cardiac reserve in rats. Indian journal of physiology and pharmacology. vol 52. issue 2. 2009-01-22. PMID:19130857. |
the observed nigella-induced cardiac hypertrophy was associated with an increase in the baseline cardiac inotropic properties as well as the maximal peak tension generation upon progressive cardiac stress by isoproterenol infusion. |
2009-01-22 |
2023-08-12 |
rat |
| Hae Jin Kee, Gwang Hyeon Eom, Hosouk Joung, Sera Shin, Ju-Ryoung Kim, Young Kuk Cho, Nakwon Choe, Bo-Woong Sim, Daewoong Jo, Myung Ho Jeong, Kyung Keun Kim, Jeong-Sun Seo, Hyun Koo. Activation of histone deacetylase 2 by inducible heat shock protein 70 in cardiac hypertrophy. Circulation research. vol 103. issue 11. 2008-12-31. PMID:18849323. |
cardiac hypertrophy was introduced by aortic banding, by infusion of isoproterenol or angiotensin ii, or by swimming. |
2008-12-31 |
2023-08-12 |
mouse |
| Evelyn T Flanagan, Maria M Buckley, Claire M Aherne, Fredolin Lainis, Munavvar Sattar, Edward J John. Impact of cardiac hypertrophy on arterial and cardiopulmonary baroreflex control of renal sympathetic nerve activity in anaesthetized rats. Experimental physiology. vol 93. issue 9. 2008-12-12. PMID:18487313. |
this study aimed to quantify the effect of cardiac hypertrophy induced with isoprenaline and caffeine on reflex regulation of renal sympathetic nerve activity by the arterial and cardiopulmonary baroreceptors. |
2008-12-12 |
2023-08-12 |
rat |