| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jing Zhu, Soojin Park, Se Hoon Kim, Chul Hoon Kim, Kyoung Hoon Jeong, Won-Joo Ki. Sirtuin 3 regulates astrocyte activation by reducing Notch1 signaling after status epilepticus. Glia. 2024-02-26. PMID:38406970. |
the upregulation of sirt3 by treatment with adjudin, a potential sirt3 activator, alleviated se-induced astrocyte activation; whereas, sirt3 deficiency exacerbated astrocyte activation in the hippocampus after se. |
2024-02-26 |
2024-02-28 |
mouse |
| Jiawei Yang, Ying Wang, Yuyan Xia, Yajie Ren, Zhi Wang, Xin Meng, Shuangyue Li, Xiaohui Liu, Jing Sha. PFOS Elicits Cytotoxicity in Neuron Through Astrocyte-Derived CaMKII-DLG1 Signaling In Vitro Rat Hippocampal Model. Neurochemical research. 2024-02-23. PMID:38393622. |
in the present study, the role of astrocyte-derived calmodulin-dependent protein kinase ii (camkii)-phosphorylated discs large homolog 1 (dlg1) signaling in pfos eliciting cytotoxicity in neuron was explored with primary cultured hippocampal astrocyte and neuron. |
2024-02-23 |
2024-02-25 |
rat |
| Hyun Seung Shin, Seung Hyun Lee, Ha Jung Moon, Yun Hee So, Hyeon Jung Jang, Kyung-Ha Lee, Changhwan Ahn, Eui-Man Jun. Prolonged stress response induced by chronic stress and corticosterone exposure causes adult neurogenesis inhibition and astrocyte loss in mouse hippocampus. Brain research bulletin. 2024-02-17. PMID:38367676. |
prolonged stress response induced by chronic stress and corticosterone exposure causes adult neurogenesis inhibition and astrocyte loss in mouse hippocampus. |
2024-02-17 |
2024-02-20 |
mouse |
| Bin Mei, Xiaoxia Xu, Juntao Weng, Yueyue Yang, Peng Wang, Gaolin Qiu, Chi Zhang, Qunlin Zhang, Yao Lu, Xuesheng Li. Activating astrocytic α2A adrenoceptors in hippocampus reduces glutamate toxicity to attenuate sepsis-associated encephalopathy in mice. Brain, behavior, and immunity. 2024-02-06. PMID:38320682. |
this study was performed to determine whether hippocampal astrocytic α2a-ar activation confers neuroprotection against sae and whether this protective effect is astrocyte specific and achieved by the modulation of glutamate metabolism. |
2024-02-06 |
2024-02-09 |
mouse |
| Nicholas Guerini Selistre, Leticia Rodrigues, Barbara Carolina Federhen, Vitor Gayger-Dias, Jéssica Taday, Krista Mineia Wartchow, Carlos-Alberto Gonçalve. S100B Secretion in Astrocytes, Unlike C6 Glioma Cells, Is Downregulated by Lactate. Metabolites. vol 14. issue 1. 2024-01-26. PMID:38276297. |
herein, we investigate the impact of fc on s100b secretion in primary astrocyte cultures, acute hippocampal slices and c6 glioma cells, as well as lactate mediation. |
2024-01-26 |
2024-01-28 |
Not clear |
| Shiva Zeini, Nahid Davoodian, Seyed Abdollah Mousav. Gamma-oryzanol attenuates lipopolysaccharide-induced cognitive impairment by modulation of hippocampal inflammatory response and glial activation in mice. Journal of neuroimmunology. vol 387. 2024-01-26. PMID:38278081. |
also, neuronal loss, microglia, and astrocyte densities were evaluated in the ca1 and ca3 hippocampus. |
2024-01-26 |
2024-01-29 |
mouse |
| Wookbong Kwon, Dong-Joo Choi, Kwanha Yu, Michael R Williamson, Sanjana Murali, Yeunjung Ko, Junsung Woo, Benjamin Denee. Comparative Transcriptomic Analysis of Cerebellar Astrocytes across Developmental Stages and Brain Regions. International journal of molecular sciences. vol 25. issue 2. 2024-01-23. PMID:38256095. |
comparing these profiles with region-specific astrocyte differentially expressed genes (degs) published for the cortex, hippocampus, and olfactory bulb revealed cerebellar-specific gene signature across these developmental timepoints. |
2024-01-23 |
2024-01-25 |
Not clear |
| Qian Li, Wei Zhang, Xin-Yu Qiao, Chong Liu, Ji-Ji Dao, Chen-Meng Qiao, Chun Cui, Yan-Qin Shen, Wei-Jiang Zha. Reducing polypyrimidine tract‑binding protein 1 fails to promote neuronal transdifferentiation on HT22 and mouse astrocyte cells under physiological conditions. Experimental and therapeutic medicine. vol 27. issue 2. 2024-01-18. PMID:38234625. |
therefore, the present study explored the effect of knocking down ptbp1 under physiological conditions on the transdifferentiation of mouse hippocampal neuron ht22 cells and mouse astrocyte (ma) cells. |
2024-01-18 |
2024-01-20 |
mouse |
| Stefanie Anders, Björn Breithausen, Petr Unichenko, Michel K Herde, Daniel Minge, Adlin Abramian, Charlotte Behringer, Tushar Deshpande, Anne Boehlen, Cátia Domingos, Lukas Henning, Julika Pitsch, Young-Bum Kim, Peter Bedner, Christian Steinhäuser, Christian Henneberge. Epileptic activity triggers rapid ROCK1-dependent astrocyte morphology changes. Glia. vol 72. issue 3. 2024-01-13. PMID:38031824. |
we uncovered astrocyte morphology changes within 10-20 min under various experimental conditions in acute hippocampal slices. |
2024-01-13 |
2024-01-15 |
Not clear |
| Yusaku Koga, Naoto Kajitani, Kotaro Miyako, Hitoshi Takizawa, Shuken Boku, Minoru Takebayash. TCF7L2: A potential key regulator of antidepressant effects on hippocampal astrocytes in depression model mice. Journal of psychiatric research. vol 170. 2024-01-12. PMID:38215648. |
clinical and preclinical studies suggest that hippocampal astrocyte dysfunction is involved in the pathophysiology of depression; however, the underlying molecular mechanisms remain unclear. |
2024-01-12 |
2024-01-15 |
mouse |
| Yusaku Koga, Naoto Kajitani, Kotaro Miyako, Hitoshi Takizawa, Shuken Boku, Minoru Takebayash. TCF7L2: A potential key regulator of antidepressant effects on hippocampal astrocytes in depression model mice. Journal of psychiatric research. vol 170. 2024-01-12. PMID:38215648. |
depression model mice exhibited typical depression-like behaviors that improved after amitriptyline treatment; the depression group mice also had significantly reduced gfap-positive astrocyte numbers in hippocampal subfields. |
2024-01-12 |
2024-01-15 |
mouse |
| Max Gentenaar, Fleur L Meulmeester, Ximaine R van der Burg, Anna T Hoekstra, Hazel Hunt, Jan Kroon, Willeke M C van Roon-Mom, Onno C Meije. Glucocorticoid receptor antagonist CORT113176 attenuates motor and neuropathological symptoms of Huntington's disease in R6/2 mice. Experimental neurology. 2024-01-12. PMID:38216109. |
it also restored hd-related parameters including astrocyte markers in both the dorsolateral striatum and the hippocampus, and microglia markers in the hippocampus. |
2024-01-12 |
2024-01-15 |
mouse |
| Kotaro Miyako, Naoto Kajitani, Yusaku Koga, Hitoshi Takizawa, Shuken Boku, Minoru Takebayash. Identification of the antidepressant effect of electroconvulsive stimulation-related genes in hippocampal astrocyte. Journal of psychiatric research. vol 170. 2024-01-09. PMID:38194849. |
identification of the antidepressant effect of electroconvulsive stimulation-related genes in hippocampal astrocyte. |
2024-01-09 |
2024-01-13 |
mouse |
| Kotaro Miyako, Naoto Kajitani, Yusaku Koga, Hitoshi Takizawa, Shuken Boku, Minoru Takebayash. Identification of the antidepressant effect of electroconvulsive stimulation-related genes in hippocampal astrocyte. Journal of psychiatric research. vol 170. 2024-01-09. PMID:38194849. |
recent studies suggest a potential role of hippocampal astrocyte in mdd and ect. |
2024-01-09 |
2024-01-13 |
mouse |
| Kotaro Miyako, Naoto Kajitani, Yusaku Koga, Hitoshi Takizawa, Shuken Boku, Minoru Takebayash. Identification of the antidepressant effect of electroconvulsive stimulation-related genes in hippocampal astrocyte. Journal of psychiatric research. vol 170. 2024-01-09. PMID:38194849. |
hence, we investigated antidepressant effect of electroconvulsive stimulation (ecs), an animal model of ect, -related genes in hippocampal astrocyte with a mouse model of mdd, in which corticosterone (cort)-induced depression-like behaviors were recovered by ecs. |
2024-01-09 |
2024-01-13 |
mouse |
| Kotaro Miyako, Naoto Kajitani, Yusaku Koga, Hitoshi Takizawa, Shuken Boku, Minoru Takebayash. Identification of the antidepressant effect of electroconvulsive stimulation-related genes in hippocampal astrocyte. Journal of psychiatric research. vol 170. 2024-01-09. PMID:38194849. |
in this model, both of cort-induced depression-like behaviors and the reduction of hippocampal astrocyte were recovered by ecs. |
2024-01-09 |
2024-01-13 |
mouse |
| Kotaro Miyako, Naoto Kajitani, Yusaku Koga, Hitoshi Takizawa, Shuken Boku, Minoru Takebayash. Identification of the antidepressant effect of electroconvulsive stimulation-related genes in hippocampal astrocyte. Journal of psychiatric research. vol 170. 2024-01-09. PMID:38194849. |
finally, serum and glucocorticoid kinase-1 (sgk1), a multi-functional protein kinase, was identified as a candidate gene reciprocally regulated by cort and ecs in hippocampal astrocyte. |
2024-01-09 |
2024-01-13 |
mouse |
| Kotaro Miyako, Naoto Kajitani, Yusaku Koga, Hitoshi Takizawa, Shuken Boku, Minoru Takebayash. Identification of the antidepressant effect of electroconvulsive stimulation-related genes in hippocampal astrocyte. Journal of psychiatric research. vol 170. 2024-01-09. PMID:38194849. |
our findings suggest a potential role of sgk1 in the antidepressant effect of ecs via the regulation of the proliferation of astrocyte and provide new insights into the involvement of hippocampal astrocyte in mdd and ect. |
2024-01-09 |
2024-01-13 |
mouse |
| Wenxue Liu, Min Jia, Keyin Zhang, Jiang Chen, Xiyu Zhu, Ruisha Li, Zhenjun Xu, Yanyu Zang, Yapeng Wang, Jun Pan, Daqing Ma, Jianjun Yang, Dongjin Wan. Increased A1 astrocyte activation-driven hippocampal neural network abnormality mediates delirium-like behavior in aged mice undergoing cardiac surgery. Aging cell. 2023-12-29. PMID:38155547. |
increased a1 astrocyte activation-driven hippocampal neural network abnormality mediates delirium-like behavior in aged mice undergoing cardiac surgery. |
2023-12-29 |
2023-12-31 |
mouse |
| Wenxue Liu, Min Jia, Keyin Zhang, Jiang Chen, Xiyu Zhu, Ruisha Li, Zhenjun Xu, Yanyu Zang, Yapeng Wang, Jun Pan, Daqing Ma, Jianjun Yang, Dongjin Wan. Increased A1 astrocyte activation-driven hippocampal neural network abnormality mediates delirium-like behavior in aged mice undergoing cardiac surgery. Aging cell. 2023-12-29. PMID:38155547. |
the results showed that surgery significantly increased hippocampal a1 astrocyte activation in aged compared to young mice. |
2023-12-29 |
2023-12-31 |
mouse |