| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yu-Wen Hung, Guan-Ling Lu, Hwei-Hsien Chen, Hsiu-Hui Tung, Sheau-Ling Le. Gliptins normalize posttraumatic hippocampal neurogenesis and restore cognitive function after controlled cortical impact on sensorimotor cortex. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 165. 2023-08-06. PMID:37544280. |
sensorimotor cortical injury thus results in an abnormal neurogenesis pattern and astrocyte reactivation in the distal hippocampus which appears to contribute to the development of cognitive dysfunction after tbi. |
2023-08-06 |
2023-08-14 |
mouse |
| Yu-Wen Hung, Guan-Ling Lu, Hwei-Hsien Chen, Hsiu-Hui Tung, Sheau-Ling Le. Gliptins normalize posttraumatic hippocampal neurogenesis and restore cognitive function after controlled cortical impact on sensorimotor cortex. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 165. 2023-08-06. PMID:37544280. |
dpp-4 inhibitors prevent astrocyte reactivation, normalize the posttraumatic hippocampal neurogenesis and help to maintain normal electrophysiology in the dg with positive behavioral effect in a mouse model. |
2023-08-06 |
2023-08-14 |
mouse |
| Lulu Xie, Jiaxin Qin, Tingting Wang, Shuai Zhang, Mingcui Luo, Xuelei Cheng, Xinrui Cao, Hui Wang, Baozhen Yao, Dan Xu, Biwen Pen. Impact of Prenatal Acetaminophen Exposure for Hippocampal Development Disorder on Mice. Molecular neurobiology. 2023-07-29. PMID:37516664. |
in addition, pace significantly decreased the expression of genes related to synaptic development in fetal hippocampal neurons and hippocampal astrocyte and microglia were also damaged to varying degrees. |
2023-07-29 |
2023-08-14 |
mouse |
| Tenna Bering, Camilla Gadgaard, Henrik Vorum, Bent Honoré, Martin Fredensborg Rat. Diurnal proteome profile of the mouse cerebral cortex: Conditional deletion of the Bmal1 circadian clock gene elevates astrocyte protein levels and cell abundance in the neocortex and hippocampus. Glia. 2023-07-20. PMID:37470358. |
diurnal proteome profile of the mouse cerebral cortex: conditional deletion of the bmal1 circadian clock gene elevates astrocyte protein levels and cell abundance in the neocortex and hippocampus. |
2023-07-20 |
2023-08-14 |
mouse |
| Si Sun, Yitong Xu, Ningxi Yu, Meifeng Zhang, Jinghui Wang, Dong Wan, Zhen Tian, Huifeng Zh. Catalpol Alleviates Ischemic Stroke Through Promoting Angiogenesis and Facilitating Proliferation and Differentiation of Neural Stem Cells via the VEGF-A/KDR Pathway. Molecular neurobiology. 2023-07-13. PMID:37439957. |
catalpol remarkably promoted angiogenesis, promoted proliferation and differentiation of neural stem cells (nscs) in the subventricular zone (svz), and prevented neuronal loss and astrocyte activation in the ischemic cortex or hippocampal dentate gyrus (dg) in vivo. |
2023-07-13 |
2023-08-14 |
rat |
| Wei Xiong, Rongzi Li, Boying Li, Xifan Wang, Huihui Wang, Yanan Sun, Xiaoyu Wang, Yixuan Li, Fazheng Re. Nobiletin Mitigates D-Galactose-Induced Memory Impairment via Improving Hippocampal Neurogenesis in Mice. Nutrients. vol 15. issue 9. 2023-07-11. PMID:37432372. |
furthermore, it downregulated the pro-inflammatory mediators il-1 β, il-6, and pp65 (by 42.2%, 22.9%, and 46.4% of those in the d-galactose treated group, respectively) in the hippocampus and blocked microglia and astrocyte activation. |
2023-07-11 |
2023-08-14 |
mouse |
| Rita Chaaya, Joel R Steele, Brian G Oliver, Hui Chen, Rita Machaalan. Effects of e-vapour and high-fat diet on the immunohistochemical staining of nicotinic acetylcholine receptors, apoptosis, microglia and astrocytes in the adult male mouse hippocampus. Journal of chemical neuroanatomy. 2023-06-21. PMID:37343645. |
this study, using a mouse model, investigated the effects of exposure to e-vapour (± nicotine) and hfd (43% fat) consumption, on the expression of nicotinic acetylcholine receptor (nachr) subunits α3, α4, α7 and β2, apoptosis markers caspase-3 and tunel, microglial marker iba-1, and astrocyte marker gfap, in hippocampal subregions of dentate gyrus (dg) and cornu ammonis (ca) 1-3. |
2023-06-21 |
2023-08-14 |
mouse |
| Ji-Ren An, Jun-Tong Liu, Xiao-Meng Gao, Qing-Feng Wang, Gui-Yan Sun, Jia-Nan Su, Chi Zhang, Jia-Xiang Yu, Yu-Feng Yang, Yan Sh. Effects of liraglutide on astrocyte polarization and neuroinflammation in db/db mice: focus on iron overload and oxidative stress. Frontiers in cellular neuroscience. vol 17. 2023-06-16. PMID:37323581. |
this study preliminarily explored the effect of liraglutide on the activation of different astrocyte phenotypes and neuroinflammation in the hippocampus of a t2dm model and further revealed its intervention effect on cognitive impairment in diabetes. |
2023-06-16 |
2023-08-14 |
mouse |
| Yi Zhong, Shengzhao Wang, Yongqiang Yin, Jialu Yu, Yang Liu, Hong Ga. Dexmedetomidine suppresses hippocampal astrocyte pyroptosis in cerebral hypoxic-ischemic neonatal rats by upregulating microRNA-148a-3p to inactivate the STAT/JMJD3 axis. International immunopharmacology. vol 121. 2023-06-16. PMID:37327511. |
dexmedetomidine suppresses hippocampal astrocyte pyroptosis in cerebral hypoxic-ischemic neonatal rats by upregulating microrna-148a-3p to inactivate the stat/jmjd3 axis. |
2023-06-16 |
2023-08-14 |
rat |
| Mathieu Letellier, Yukiko God. Astrocyte calcium signaling shifts the polarity of presynaptic plasticity. Neuroscience. 2023-06-09. PMID:37295597. |
previously, we have identified a role for astrocyte nmda receptor and l-vgcc signaling in heterosynaptic presynaptic plasticity and promoting the heterogeneity of presynaptic strengths at hippocampal synapses. |
2023-06-09 |
2023-08-14 |
Not clear |
| Young-Jun Lee, Chiyeon Lim, Sehyun Lim, Suin Ch. Tooth-Cutting-Induced Maxillary Malocclusion Exacerbates Cognitive Deficit in a Mouse Model of Vascular Dementia. Brain sciences. vol 13. issue 5. 2023-05-27. PMID:37239252. |
moreover, inflammatory responses were induced via astrocyte activation in the hippocampal region of the brain, and the proteins involved in inflammatory responses were found to be involved in these changes. |
2023-05-27 |
2023-08-14 |
mouse |
| Song-Ji Li, Min-Hui Ma, Jun-Mei Li, Xiao-Yu Lu, Cheng-Biao Lu, Shi-Fen Zhou, Lin-Xuan Zhang, Meng-Qing Li, Tong-Ze Shao, Su-Ping Bai, Xiao-Xin Yan, Fang Li, Chang-Qi L. CNTN1 Aggravates Neuroinflammation and Triggers Cognitive Deficits in Male Mice by Boosting Crosstalk between Microglia and Astrocytes. Aging and disease. 2023-05-17. PMID:37196127. |
the mechanisms underlying these cognitive deficits could be attributed to hippocampal microglia and astrocyte activation, which led to aberrant expression of excitatory amino acid transporters (eaat)1/eaat2. |
2023-05-17 |
2023-08-14 |
mouse |
| Rafael Short Ferreira, Paulo Roberto Ribeiro, Juliana Helena Castro E Silva, Juliana Bender Hoppe, Monique Marylin Alves de Almeida, Beatriz Correia de Lima Ferreira, Gustavo Borges Andrade, Suzana Braga de Souza, Luzimar Gonzaga Ferdandez, Maria de Fátima Dias Costa, Christianne Gazzana Salbego, Andrea Domenico Rivera, Aline Longoni, Adriano Martimbianco de Assis, Francesca Pieropan, José Cláudio Fonseca Moreira, Silvia Lima Costa, Arthur Morgan Butt, Victor Diogenes Amaral da Silv. Amburana cearensis seed extract stimulates astrocyte glutamate homeostatic mechanisms in hippocampal brain slices and protects oligodendrocytes against ischemia. BMC complementary medicine and therapies. vol 23. issue 1. 2023-05-11. PMID:37170258. |
amburana cearensis seed extract stimulates astrocyte glutamate homeostatic mechanisms in hippocampal brain slices and protects oligodendrocytes against ischemia. |
2023-05-11 |
2023-08-14 |
Not clear |
| Eunbeol Lee, Yeon-Joo Jung, Yu Rim Park, Seongjoon Lim, Young-Jin Choi, Se Young Lee, Chan Hyuk Kim, Ji Young Mun, Won-Suk Chun. A distinct astrocyte subtype in the aging mouse brain characterized by impaired protein homeostasis. Nature aging. vol 2. issue 8. 2023-04-28. PMID:37118130. |
here, we identified a unique astrocyte subtype that exhibits dysregulated autophagy and morphology in aging hippocampus. |
2023-04-28 |
2023-08-14 |
mouse |
| b' Nikola \\xc5\\xa0utulovi\\xc4\\x87, Milena Veskovi\\xc4\\x87, Nela Pu\\xc5\\xa1ka\\xc5\\xa1, Aleksa Zubeli\\xc4\\x87, Djurdja Jeroti\\xc4\\x87, Sonja \\xc5\\xa0uvakov, Sanja Despotovi\\xc4\\x87, \\xc5\\xbdeljko Gruba\\xc4\\x8d, Du\\xc5\\xa1an Mladenovi\\xc4\\x87, Djuro Macut, Aleksandra Ra\\xc5\\xa1i\\xc4\\x87-Markovi\\xc4\\x87, Tatjana Simi\\xc4\\x87, Olivera Stanojlovi\\xc4\\x87, Dragan Hrn\\xc4\\x8di\\xc4\\x8. Chronic Prostatitis/Chronic Pelvic Pain Syndrome Induces Depression-Like Behavior and Learning-Memory Impairment: A Possible Link with Decreased Hippocampal Neurogenesis and Astrocyte Activation. Oxidative medicine and cellular longevity. vol 2023. 2023-04-17. PMID:37064799.' |
chronic prostatitis/chronic pelvic pain syndrome induces depression-like behavior and learning-memory impairment: a possible link with decreased hippocampal neurogenesis and astrocyte activation. |
2023-04-17 |
2023-08-14 |
rat |
| Yan Sun, Huaiwu Zhang, Xuan Zhang, Wenzhao Wang, Yong Chen, Zhiyou Cai, Qihui Wang, Jun Wang, Yi Sh. Promotion of astrocyte-neuron glutamate-glutamine shuttle by SCFA contributes to the alleviation of Alzheimer's disease. Redox biology. vol 62. 2023-04-05. PMID:37018970. |
single-cell rna sequencing analysis of the hippocampus revealed scfa can enhance astrocyte-neuron communication including glutamate-glutamine shuttle, mainly by acting on astrocyte in vivo. |
2023-04-05 |
2023-08-14 |
mouse |
| Yang Du, Yan-Li Wang, Lei Chen, Qi-En Li, Yong Chen. Anti-depressant-like effects of rannasangpei and its active ingredient crocin-1 on chronic unpredictable mild stress mice. Frontiers in pharmacology. vol 14. 2023-04-03. PMID:37007014. |
moreover, our data indicated that rsnp or crocin-1 increased astrocyte number and brain-derived neurotrophic factor levels in the hippocampus of cums-treated mice after rsnp or crocin-1 administration. |
2023-04-03 |
2023-08-14 |
mouse |
| Mandy S J Kater, Katharina F Baumgart, Aina Badia-Soteras, Tim S Heistek, Karen E Carney, A Jacob Timmerman, Jan R T van Weering, August B Smit, Marjo S van der Knaap, Huibert D Mansvelder, Mark H G Verheijen, Rogier Mi. A novel role for MLC1 in regulating astrocyte-synapse interactions. Glia. 2023-04-01. PMID:37002718. |
here, we show that mlc1 is present in distal astrocyte processes, also known as perisynaptic astrocyte processes (paps) or astrocyte leaflets, which closely interact with excitatory synapses in the ca1 region of the hippocampus. |
2023-04-01 |
2023-08-14 |
mouse |
| João Filipe Viana, João Luís Machado, Daniela Sofia Abreu, Alexandra Veiga, Sara Barsanti, Gabriela Tavares, Manuella Martins, Vanessa Morais Sardinha, Sónia Guerra-Gomes, Cátia Domingos, Alberto Pauletti, Jérôme Wahis, Chen Liu, Corrado Calì, Christian Henneberger, Matthew G Holt, João Filipe Oliveir. Astrocyte structural heterogeneity in the mouse hippocampus. Glia. 2023-03-23. PMID:36949723. |
astrocyte structural heterogeneity in the mouse hippocampus. |
2023-03-23 |
2023-08-14 |
mouse |
| João Filipe Viana, João Luís Machado, Daniela Sofia Abreu, Alexandra Veiga, Sara Barsanti, Gabriela Tavares, Manuella Martins, Vanessa Morais Sardinha, Sónia Guerra-Gomes, Cátia Domingos, Alberto Pauletti, Jérôme Wahis, Chen Liu, Corrado Calì, Christian Henneberger, Matthew G Holt, João Filipe Oliveir. Astrocyte structural heterogeneity in the mouse hippocampus. Glia. 2023-03-23. PMID:36949723. |
recent transcriptomic studies described astrocyte molecular diversity, suggesting structural heterogeneity in regions such as the hippocampus, which is crucial for cognitive and emotional behaviors. |
2023-03-23 |
2023-08-14 |
mouse |