| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qiong Wu, Min Yu, Zhen Wang, Xiaohong Ai, Zhenghai Liu, Jiayu Zeng, Cai Li, Lei Yuan, Jie He, Xinping Lin, Wei Wa. Alternate-day fasting for the protection of cognitive impairment in c57BL/6J mice following whole-brain radiotherapy. Neurochemistry international. 2022-12-13. PMID:36513311. |
according to our study, this is the first time we found that adf improved cognitive dysfunction induced by irradiation, and the anti-inflammatory effect of adf could be due to inhibition in nlrp3-mediated hippocampal neuronal loss by suppressing astrocyte activation. |
2022-12-13 |
2023-08-14 |
mouse |
| Alexander Maltsev, Matvey Roshchin, Ilya Bezprozvanny, Ivan Smirnov, Olga Vlasova, Pavel Balaban, Anastasia Borodinov. Bidirectional regulation by "star forces": Ionotropic astrocyte's optical stimulation suppresses synaptic plasticity, metabotropic one strikes back. Hippocampus. 2022-12-09. PMID:36484471. |
using the aav-based delivery strategy, we expressed the ionotropic channelrhodopsin-2 (chr2) or the metabotropic gq-coupled opto-a1ar opsins specifically in hippocampal astrocytes to compare different modalities of astrocyte activation. |
2022-12-09 |
2023-08-14 |
Not clear |
| Brian Griffiths, Lijun Xu, Xiaoyun Sun, Majesty Greer, Isabella Murray, Creed Star. Inhibition of microRNA-200c preserves astrocyte sirtuin-1 and mitofusin-2, and protects against hippocampal neurodegeneration following global cerebral ischemia in mice. Frontiers in molecular neuroscience. vol 15. 2022-12-05. PMID:36466801. |
inhibition of microrna-200c preserves astrocyte sirtuin-1 and mitofusin-2, and protects against hippocampal neurodegeneration following global cerebral ischemia in mice. |
2022-12-05 |
2023-08-14 |
mouse |
| Osamu Nozawa, Muneaki Miyata, Hajime Shiotani, Takeshi Kameyama, Ryouhei Komaki, Tatsuhiro Shimizu, Toshihiko Kuriu, Yutaro Kashiwagi, Yuka Sato, Michinori Koebisu, Atsu Aiba, Shigeo Okabe, Kiyohito Mizutani, Yoshimi Taka. A novel Necl-2/3-mediated mechanism for tripartite synapse formation. Development (Cambridge, England). 2022-12-02. PMID:36458527. |
studies on hippocampal mossy fiber synapses in necl-3 knockout and necl-2/3 double knockout mice confirmed these novel mechanisms for astrocyte-synapse interactions and astrocyte functional polarization in vivo. |
2022-12-02 |
2023-08-14 |
mouse |
| Julian Karpf, Petr Unichenko, Nicholas Chalmers, Felix Beyer, Marie-Theres Wittmann, Julia Schneider, Elif Fidan, Andre Reis, Jan Beckervordersandforth, Sebastian Brandner, Stefan Liebner, Sven Falk, Andreas Sagner, Christian Henneberger, Ruth Beckervordersandfort. Dentate gyrus astrocytes exhibit layer-specific molecular, morphological and physiological features. Nature neuroscience. 2022-11-28. PMID:36443610. |
here we show that the adult mouse dentate gyrus (dg) of the hippocampus is populated by molecularly distinct astrocyte subtypes that are associated with distinct dg layers. |
2022-11-28 |
2023-08-14 |
mouse |
| Yinong Zhang, Shihui Kuai, Yi Zhang, Hang Xue, Ziyi Wu, Ping Zha. Maternal sevoflurane exposure affects neural stem cell differentiation in offspring rats through NRF2 signaling. Neurotoxicology. vol 93. 2022-11-21. PMID:36404432. |
however, neuronal reduction and astrocyte proliferation were observed in the rat hippocampus at p28. |
2022-11-21 |
2023-08-14 |
rat |
| Yinong Zhang, Shihui Kuai, Yi Zhang, Hang Xue, Ziyi Wu, Ping Zha. Maternal sevoflurane exposure affects neural stem cell differentiation in offspring rats through NRF2 signaling. Neurotoxicology. vol 93. 2022-11-21. PMID:36404432. |
prenatal sevoflurane exposure promotes neuronal and astrocytic differentiation of nscs in the fetal rat brain, leading to long-term neuron reduction but astrocyte proliferation in the postnatal rat hippocampus. |
2022-11-21 |
2023-08-14 |
rat |
| Marco Colizzi, Riccardo Bortoletto, Chiara Colli, Enrico Bonomo, Daniele Pagliaro, Elisa Maso, Gianfranco Di Gennaro, Matteo Balestrier. Therapeutic effect of palmitoylethanolamide in cognitive decline: A systematic review and preliminary meta-analysis of preclinical and clinical evidence. Frontiers in psychiatry. vol 13. 2022-11-17. PMID:36387000. |
pea was found to promote neurogenesis, especially in the hippocampus, neuronal viability and survival, and microtubule-associated protein 2 and brain-derived neurotrophic factor expression, while inhibiting mast cell infiltration/degranulation and astrocyte activation. |
2022-11-17 |
2023-08-14 |
human |
| Shveta V Parekh, Lydia O Adams, Gillian A Barkell, Donald T Lysl. MDMA administration attenuates hippocampal IL-β immunoreactivity and subsequent stress-enhanced fear learning: An animal model of PTSD. Brain, behavior, & immunity - health. vol 26. 2022-11-17. PMID:36388136. |
the current studies test the hypothesis that mdma is capable of attenuating sefl and inducing alterations in expression of tnf-α, il-1β, glial fibrillary acidic protein (gfap), an astrocyte specific marker, and ionized calcium-binding adapter molecule -1 (iba-1), a microglial specific marker, in the dorsal hippocampus (dh) following a severe stressor in male animals. |
2022-11-17 |
2023-08-14 |
Not clear |
| Xiao Liu, Su-Su Tang, Si-Ming Liu, Jie Zeng, Zhi-Gang Chen, Cai-Hong Liu, Rong-Hao Mu, Dan-Hua Yuan, Jia-Jia Zhao, Hao Hong, Hao Wan. Deficiency of astrocyte CysLT Neurobiology of disease. 2022-11-12. PMID:36371059. |
deficiency of astrocyte cyslt our previous study suggests that hippocampal cysteinyl leukotriene receptor 1 (cyslt |
2022-11-12 |
2023-08-14 |
Not clear |
| Yingjuan Xu, Jiling Zhang, Zeman Fang, Handi Zhan. The effects of social defeat stress on hippocampal glial cells and interleukin-6 in adolescence and adulthood. Neuroreport. vol 33. issue 18. 2022-11-11. PMID:36367792. |
the purpose of this study is to investigate the dynamic changes of the hippocampal neuroinflammatory mediators, including microglia, astrocyte, and interleukin-6 (il-6) levels in mice experiencing social defeat stress during adolescence. |
2022-11-11 |
2023-08-14 |
mouse |
| Yingjuan Xu, Jiling Zhang, Zeman Fang, Handi Zhan. The effects of social defeat stress on hippocampal glial cells and interleukin-6 in adolescence and adulthood. Neuroreport. vol 33. issue 18. 2022-11-11. PMID:36367792. |
the hippocampal microglia, astrocyte, and il-6 levels were measured 24 h and 3 weeks after the end of stress exposure. |
2022-11-11 |
2023-08-14 |
mouse |
| Woo-Hyun Cho, Kyungchul Noh, Byung Hun Lee, Ellane Barcelon, Sang Beom Jun, Hye Yoon Park, Sung Joong Le. Hippocampal astrocytes modulate anxiety-like behavior. Nature communications. vol 13. issue 1. 2022-11-07. PMID:36344520. |
here we showed that hippocampal astrocyte calcium activity reflects mouse affective state during virtual elevated plus maze test using two-photon calcium imaging in vivo. |
2022-11-07 |
2023-08-14 |
mouse |
| Woo-Hyun Cho, Kyungchul Noh, Byung Hun Lee, Ellane Barcelon, Sang Beom Jun, Hye Yoon Park, Sung Joong Le. Hippocampal astrocytes modulate anxiety-like behavior. Nature communications. vol 13. issue 1. 2022-11-07. PMID:36344520. |
furthermore, optogenetic hippocampal astrocyte activation elevating intracellular calcium induced anxiolytic behaviors in astrocyte-specific channelrhodopsin 2 (chr2) transgenic mice (hgfap-chr2 mice). |
2022-11-07 |
2023-08-14 |
mouse |
| Adriana L Silva, Joana L Oliveira, Ravena P do Nascimento, Letícia O Santos, Fillipe M de Araújo, Balbino L Dos Santos, Rejane C Santana, Eduardo Luiz T Moreira, Maria José M Batatinha, Iura M Alves, Eudes S Velozo, Mauricio M Victor, Adriano M Assis, Roberto F Almeida, Diogo O G de Souza, Victor Diógenes A Silva, Silvia L Cost. Monocrotaline induces acutely cerebrovascular lesions, astrogliosis and neuronal degeneration associated with behavior changes in rats: a model of vascular damage in perspective. Neurotoxicology. 2022-11-06. PMID:36336098. |
mct also induced neurotoxicity in the cortex and hippocampus, as revealed by fluoro jade-b and cresyl violet staining, as well astrocyte reactivity, revealed by immunocytochemistry for glial fibrillary acidic protein. |
2022-11-06 |
2023-08-14 |
rat |
| Adriana L Silva, Joana L Oliveira, Ravena P do Nascimento, Letícia O Santos, Fillipe M de Araújo, Balbino L Dos Santos, Rejane C Santana, Eduardo Luiz T Moreira, Maria José M Batatinha, Iura M Alves, Eudes S Velozo, Mauricio M Victor, Adriano M Assis, Roberto F Almeida, Diogo O G de Souza, Victor Diógenes A Silva, Silvia L Cost. Monocrotaline induces acutely cerebrovascular lesions, astrogliosis and neuronal degeneration associated with behavior changes in rats: a model of vascular damage in perspective. Neurotoxicology. 2022-11-06. PMID:36336098. |
together, these results demonstrate that the ingestion of mct induces cerebrovascular lesions and toxicity to neurons that are associated to astroglial cell response and neuroinflammation in the cortex and hippocampus of rats, highlighting cns damages after acute intoxication, also putting in perspective it uses as a model for cerebrovascular damage. |
2022-11-06 |
2023-08-14 |
rat |
| Lucy M V Gee, Ben Barron-Millar, Jack Leslie, Claire Richardson, Marco Y W Zaki, Saimir Luli, Rachel A Burgoyne, Rainie I T Cameron, Graham R Smith, John G Brain, Barbara Innes, Laura Jopson, Jessica K Dyson, Katherine R C McKay, Alexandros Pechlivanis, Elaine Holmes, Rolando Berlinguer-Palmini, Stella Victorelli, George F Mells, Richard N Sandford, Jeremy Palmer, John A Kirby, Christos Kiourtis, Joao Mokochinski, Zoe Hall, Thomas G Bird, Lee A Borthwick, Christopher M Morris, Peter S Hanson, Diana Jurk, Elizabeth A Stoll, Fiona E N LeBeau, David E J Jones, Fiona Oakle. Anti-Cholestatic therapy with Obeticholic Acid improves short term memory in bile duct ligated mice. The American journal of pathology. 2022-10-15. PMID:36243043. |
bdl animals, exhibited short-term memory loss, showed reduced astrocyte coverage of the blood-brain barrier, destabilised hippocampal network activity and neuronal senescence. |
2022-10-15 |
2023-08-14 |
mouse |
| Mohammed Al-Onaizi, Ahmad Al-Sarraf, Kawthar Braysh, Fatema Kazem, Heba Al-Hussaini, Muddanna Rao, Narayana Kilarkaje, Ayman ElAl. Impaired spatial navigation and age-dependent hippocampal synaptic dysfunction are associated with chronic inflammatory response in db/db mice. The European journal of neuroscience. 2022-10-13. PMID:36226387. |
we found that astrocyte density was significantly decreased in all regions of the hippocampus in t2dm mice. |
2022-10-13 |
2023-08-14 |
mouse |
| Ning Zhang, Yuan Shen, Weikang Zhu, Chenyu Li, Shuqing Liu, Hongying Li, Yong Wang, Junmeng Wang, Qun Zhang, Jiayi Sun, Lushuang Xie, Shuguang Yu, Qiaofeng W. Spatial transcriptomics shows moxibustion promotes hippocampus astrocyte and neuron interaction. Life sciences. 2022-10-11. PMID:36220370. |
spatial transcriptomics shows moxibustion promotes hippocampus astrocyte and neuron interaction. |
2022-10-11 |
2023-08-14 |
Not clear |
| Travis Walrath, Rachel H McMahan, Juan-Pablo Idrovo, Nidia Quillinan, Elizabeth J Kovac. Cutaneous burn injury induces neuroinflammation and reactive astrocyte activation in the hippocampus of agedz mice. Experimental gerontology. 2022-10-08. PMID:36208823. |
cutaneous burn injury induces neuroinflammation and reactive astrocyte activation in the hippocampus of agedz mice. |
2022-10-08 |
2023-08-14 |
mouse |