| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aleksandra Glavaski-Joksimovic, Tamas Virag, Qin A Chang, Neva C West, Thomas A Mangatu, Michael P McGrogan, Millicent Dugich-Djordjevic, Martha C Boh. Reversal of dopaminergic degeneration in a parkinsonian rat following micrografting of human bone marrow-derived neural progenitors. Cell transplantation. vol 18. issue 7. 2010-07-08. PMID:19796495. |
parkinson's disease (pd) is a common neurodegenerative disease characterized by the selective loss of dopaminergic (da) neurons in the midbrain. |
2010-07-08 |
2023-08-12 |
human |
| Ilse Sanet Pienaar, David Trevor Dexter, Pierre Roland Burkhar. Mitochondrial proteomics as a selective tool for unraveling Parkinson's disease pathogenesis. Expert review of proteomics. vol 7. issue 2. 2010-06-28. PMID:20377388. |
parkinson's disease (pd) is a neurodegenerative disease characterized by the large-scale loss of dopaminergic neurons in the substantia nigra and the formation of protein aggregates that accumulate in the cytoplasm of the remaining dopaminergic neurons. |
2010-06-28 |
2023-08-12 |
human |
| T J Vol. Neuropharmacological mechanisms underlying the neuroprotective effects of methylphenidate. Current neuropharmacology. vol 6. issue 4. 2010-06-11. PMID:19587858. |
understanding these neuropharmacological mechanisms of methylphenidate neuroprotection may provide important insights into the physiologic regulation of dopaminergic systems as well as the pathophysiology of a variety of disorders involving abnormal dopamine disposition ranging from substance abuse to neurodegenerative diseases such as parkinson's disease. |
2010-06-11 |
2023-08-12 |
Not clear |
| Alida Filippi, Julia Mahler, Jörn Schweitzer, Wolfgang Drieve. Expression of the paralogous tyrosine hydroxylase encoding genes th1 and th2 reveals the full complement of dopaminergic and noradrenergic neurons in zebrafish larval and juvenile brain. The Journal of comparative neurology. vol 518. issue 4. 2010-03-23. PMID:20017209. |
the development of dopaminergic and noradrenergic neurons has received much attention based on their modulatory effect on many behavioral circuits and their involvement in neurodegenerative diseases. |
2010-03-23 |
2023-08-12 |
zebrafish |
| Mario Di Napol. New molecular avenues in Parkinson's disease therapy. Current topics in medicinal chemistry. vol 9. issue 10. 2010-03-04. PMID:19754406. |
idiopathic parkinson's disease (pd) is a progressive neurodegenerative disease characterized by dopaminergic neuronal loss within the substantia nigra. |
2010-03-04 |
2023-08-12 |
Not clear |
| Miguel A Ortiz-Ortiz, José M Morán, Luz M Ruiz-Mesa, Mireia Niso-Santano, José M Bravo-SanPedro, Rubén Gómez-Sánchez, Rosa A González-Polo, José M Fuente. Curcumin exposure induces expression of the Parkinson's disease-associated leucine-rich repeat kinase 2 (LRRK2) in rat mesencephalic cells. Neuroscience letters. vol 468. issue 2. 2010-03-04. PMID:19879924. |
since oxidative stress has been implicated in the degeneration of dopaminergic neurons in the substantia nigra in parkinson's disease (pd), curcumin has been proposed to have potential therapeutic value for the treatment of neurodegenerative diseases such as pd. |
2010-03-04 |
2023-08-12 |
rat |
| Hideaki Matsui, Yoshihito Taniguchi, Haruhisa Inoue, Yoshito Kobayashi, Yoshiyuki Sakaki, Atsushi Toyoda, Kengo Uemura, Daisuke Kobayashi, Shunichi Takeda, Ryosuke Takahash. Loss of PINK1 in medaka fish (Oryzias latipes) causes late-onset decrease in spontaneous movement. Neuroscience research. vol 66. issue 2. 2010-03-02. PMID:19895857. |
parkinson's disease is a neurodegenerative disease associated with the degeneration of dopaminergic neurons in the substantia nigra. |
2010-03-02 |
2023-08-12 |
mouse |
| Zhi Yao, Nicholas W Woo. Cell death pathways in Parkinson's disease: role of mitochondria. Antioxidants & redox signaling. vol 11. issue 9. 2010-03-01. PMID:19422283. |
parkinson's disease (pd) is a progressive neurodegenerative disease and is characterized pathologically by selective loss of nigrostriatal dopaminergic neurons and the formation of lewy bodies. |
2010-03-01 |
2023-08-12 |
human |
| Olivier Preynat-Seauve, Pierre R Burkhard, Jean Villard, Walter Zingg, Nathalie Ginovart, Anis Feki, Michel Dubois-Dauphin, Samia A Hurst, Alex Mauron, Marisa Jaconi, Karl-Heinz Kraus. Pluripotent stem cells as new drugs? The example of Parkinson's disease. International journal of pharmaceutics. vol 381. issue 2. 2010-02-04. PMID:19782880. |
it is one of the most prevalent neurodegenerative diseases caused by the loss of dopaminergic neurons in the substantia nigra pars compacta. |
2010-02-04 |
2023-08-12 |
Not clear |
| Raphael Béné, Sonja Antić, Mislav Budisić, Marijana Lisak, Zlatko Trkanjec, Vida Demarin, Slava Podobnik-Sarkanj. Parkinson's disease. Acta clinica Croatica. vol 48. issue 3. 2010-01-29. PMID:20055267. |
parkinson's disease is one of the most common neurodegenerative diseases caused by degeneration of dopaminergic neurons in substantia nigra. |
2010-01-29 |
2023-08-12 |
Not clear |
| Hideaki Matsui, Yoshihito Taniguchi, Haruhisa Inoue, Kengo Uemura, Shunichi Takeda, Ryosuke Takahash. A chemical neurotoxin, MPTP induces Parkinson's disease like phenotype, movement disorders and persistent loss of dopamine neurons in medaka fish. Neuroscience research. vol 65. issue 3. 2010-01-18. PMID:19665499. |
parkinson's disease (pd) is the second most common neurodegenerative disease associated with the degeneration of dopaminergic neurons in the substantia nigra. |
2010-01-18 |
2023-08-12 |
human |
| Minho Moon, Hyo Geun Kim, Lakkyong Hwang, Ji-Hyung Seo, Sehee Kim, Sunyoung Hwang, Soonyong Kim, Dahm Lee, Hyunju Chung, Myung Sook Oh, Kyung-Tae Lee, Seungjoon Par. Neuroprotective effect of ghrelin in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease by blocking microglial activation. Neurotoxicity research. vol 15. issue 4. 2010-01-11. PMID:19384567. |
our data indicate that ghrelin may act as a survival factor for dopaminergic neurons by functioning as a microglia-deactivating factor and suggest that ghrelin may be a valuable therapeutic agent for neurodegenerative diseases such as pd. |
2010-01-11 |
2023-08-12 |
mouse |
| Jin Young Shin, Hyun-Jung Park, Young Hwan Ahn, Phil Hyu Le. Neuroprotective effect of L-dopa on dopaminergic neurons is comparable to pramipexol in MPTP-treated animal model of Parkinson's disease: a direct comparison study. Journal of neurochemistry. vol 111. issue 4. 2009-11-06. PMID:19765187. |
parkinson's disease (pd) is a chronic neurodegenerative disease characterized by selective loss of dopaminergic neurons in the pars compacta of the substantia nigra. |
2009-11-06 |
2023-08-12 |
mouse |
| Pol Giménez-Xavier, Roser Francisco, Antonio F Santidrián, Joan Gil, Santiago Ambrosi. Effects of dopamine on LC3-II activation as a marker of autophagy in a neuroblastoma cell model. Neurotoxicology. vol 30. issue 4. 2009-10-27. PMID:19410601. |
their identification is important in the study of neurodegenerative diseases that specifically involve dopaminergic neurons. |
2009-10-27 |
2023-08-12 |
human |
| Daniela Moniz Arduíno, A Raquel Esteves, Sandra M Cardoso, Catarina R Oliveir. Endoplasmic reticulum and mitochondria interplay mediates apoptotic cell death: relevance to Parkinson's disease. Neurochemistry international. vol 55. issue 5. 2009-10-26. PMID:19375464. |
sporadic parkinson's disease (pd) is a progressive neurodegenerative disease characterized by a loss of dopaminergic neurons in the substantia nigra pars compacta. |
2009-10-26 |
2023-08-12 |
Not clear |
| Wing-Sai Chan, Siva Sundara Kumar Durairajan, Jia-Hong Lu, Yan Wang, Li-Xia Xie, Wan-Fung Kum, Irene Koo, Ken Kin Lam Yung, Min L. Neuroprotective effects of Astragaloside IV in 6-hydroxydopamine-treated primary nigral cell culture. Neurochemistry international. vol 55. issue 6. 2009-10-09. PMID:19409437. |
in the present study, astragaloside iv (as-iv) extracted from the dried root of astragalus membranaceus, a well-known chinese medicine used for the treatment of neurodegenerative diseases, was investigated for its capacity to protect dopaminergic neurons in experimental parkinson's disease. |
2009-10-09 |
2023-08-12 |
Not clear |
| Sehee Kim, Minho Moon, Seungjoon Par. Exendin-4 protects dopaminergic neurons by inhibition of microglial activation and matrix metalloproteinase-3 expression in an animal model of Parkinson's disease. The Journal of endocrinology. vol 202. issue 3. 2009-09-23. PMID:19570816. |
our data indicate that exendin-4 may act as a survival factor for dopaminergic neurons by functioning as a microglia-deactivating factor and suggest that exendin-4 may be a valuable therapeutic agent for neurodegenerative diseases such as pd. |
2009-09-23 |
2023-08-12 |
mouse |
| H Jourdi, L Hamo, T Oka, A Seegan, M Baudr. BDNF mediates the neuroprotective effects of positive AMPA receptor modulators against MPP+-induced toxicity in cultured hippocampal and mesencephalic slices. Neuropharmacology. vol 56. issue 5. 2009-07-02. PMID:19371576. |
neurotoxicity is involved in various neurodegenerative diseases including parkinson's disease (pd), which affects mesencephalic dopaminergic neurons of the substantia nigra (sn). |
2009-07-02 |
2023-08-12 |
Not clear |
| Julia Fuchs, Jakob C Mueller, Peter Lichtner, Claudia Schulte, Marita Munz, Daniela Berg, Ullrich Wüllner, Thomas Illig, Manu Sharma, Thomas Gasse. The transcription factor PITX3 is associated with sporadic Parkinson's disease. Neurobiology of aging. vol 30. issue 5. 2009-06-22. PMID:17905480. |
parkinson's disease (pd) is a progressive neurodegenerative disease with typical motor symptoms due to the preferential loss of midbrain dopaminergic (mda) neurons in the substantia nigra pars compacta. |
2009-06-22 |
2023-08-12 |
Not clear |
| Paula Luciana Scalzo, Nilo Ikuta, Francisco Cardoso, Andrea Regner, Antônio Lúcio Teixeir. Quantitative plasma DNA analysis in Parkinson's disease. Neuroscience letters. vol 452. issue 1. 2009-06-11. PMID:19444939. |
parkinson disease (pd) is a neurodegenerative disease resulting from the loss of the dopaminergic neurons from the substantia nigra pars compacta (snpc). |
2009-06-11 |
2023-08-12 |
human |