| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Smitha Karunakaran, Uzma Saeed, Mamata Mishra, R Khader Valli, Shanker Datt Joshi, Durga Praveen Meka, Pankaj Seth, Vijayalakshmi Ravindranat. Selective activation of p38 mitogen-activated protein kinase in dopaminergic neurons of substantia nigra leads to nuclear translocation of p53 in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 47. 2009-06-09. PMID:19020042. |
parkinson's disease (pd) is a progressive neurodegenerative disease characterized by the degeneration of the dopaminergic neurons in the substantia nigra pars compacta (snpc). |
2009-06-09 |
2023-08-12 |
mouse |
| Ted M Dawso. Unraveling the role of defective genes in Parkinson's disease. Parkinsonism & related disorders. vol 13 Suppl 3. 2009-04-01. PMID:18267244. |
parkinson's disease (pd) is a common neurodegenerative disease characterized by the loss of dopaminergic neurons leading to bradykinesia, rest tremor and rigidity. |
2009-04-01 |
2023-08-12 |
Not clear |
| Hiroki Takeuchi, Takashi Yanagida, Masatoshi Inden, Kazuyuki Takata, Yoshihisa Kitamura, Kentaro Yamakawa, Hideyuki Sawada, Yasuhiko Izumi, Noriyuki Yamamoto, Takeshi Kihara, Kengo Uemura, Haruhisa Inoue, Takashi Taniguchi, Akinori Akaike, Ryosuke Takahashi, Shun Shimoham. Nicotinic receptor stimulation protects nigral dopaminergic neurons in rotenone-induced Parkinson's disease models. Journal of neuroscience research. vol 87. issue 2. 2009-03-25. PMID:18803299. |
parkinson's disease (pd) is the second most common neurodegenerative disease and is characterized by dopaminergic (da) neuronal cell loss in the substantia nigra. |
2009-03-25 |
2023-08-12 |
mouse |
| Jaana M Jurvansuu, Adrian Goldma. Recent inventions on receptor tyrosine kinase RET modulation. Recent patents on biotechnology. vol 2. issue 1. 2009-03-16. PMID:19075852. |
therefore, the neuroprotective capacity of ret activation to override the apoptotic program in neurodegenerative diseases, like in dying midbrain dopaminergic neurons in parkinson's disease, is of great interest. |
2009-03-16 |
2023-08-12 |
Not clear |
| I A Prescott, J O Dostrovsky, E Moro, M Hodaie, A M Lozano, W D Hutchiso. Levodopa enhances synaptic plasticity in the substantia nigra pars reticulata of Parkinson's disease patients. Brain : a journal of neurology. vol 132. issue Pt 2. 2009-03-10. PMID:19050033. |
parkinson's disease, caused by the loss of dopaminergic nigrostriatal projections, is a debilitating neurodegenerative disease characterized by bradykinesia, rigidity, tremor and postural instability. |
2009-03-10 |
2023-08-12 |
rat |
| Rebecca L Miller, Marilyn James-Kracke, Grace Y Sun, Albert Y Su. Oxidative and inflammatory pathways in Parkinson's disease. Neurochemical research. vol 34. issue 1. 2009-02-23. PMID:18363100. |
parkinson's disease (pd) is the second most prevalent age-related neurodegenerative disease with physiological manifestations including tremors, bradykinesia, abnormal postural reflexes, rigidity and akinesia and pathological landmarks showing losses of dopaminergic neurons in the substantia nigra. |
2009-02-23 |
2023-08-12 |
Not clear |
| Frank J S Lee, Fang Li. Genetic factors involved in the pathogenesis of Parkinson's disease. Brain research reviews. vol 58. issue 2. 2008-12-18. PMID:18313759. |
parkinson's disease (pd) is a neurodegenerative disease characterized by a loss of nigrostriatal dopaminergic neurons. |
2008-12-18 |
2023-08-12 |
Not clear |
| Samad Nadri, Masoud Soleimani, Zahra Mobarra, Sepideh Amin. Expression of dopamine-associated genes on conjunctiva stromal-derived human mesenchymal stem cells. Biochemical and biophysical research communications. vol 377. issue 2. 2008-12-05. PMID:18851950. |
parkinson's disease (pd) is neurodegenerative diseases caused by the loss of dopaminergic neurons in the substantia nigra pars compacta. |
2008-12-05 |
2023-08-12 |
human |
| Evelien Huisman, Harry B M Uylings, Piet V Hooglan. Gender-related changes in increase of dopaminergic neurons in the olfactory bulb of Parkinson's disease patients. Movement disorders : official journal of the Movement Disorder Society. vol 23. issue 10. 2008-11-18. PMID:18581481. |
gender differences in dopaminergic related neurodegenerative diseases have hardly been studied until now. |
2008-11-18 |
2023-08-12 |
human |
| Chun-Yao Lee, Chien-Hsing Lee, Chien-Cheng Shih, Horng-Huei Lio. Paraquat inhibits postsynaptic AMPA receptors on dopaminergic neurons in the substantia nigra pars compacta. Biochemical pharmacology. vol 76. issue 9. 2008-11-05. PMID:18761327. |
parkinson's disease (pd) is a neurodegenerative disease that mainly affects dopaminergic (da-ergic) neurons in the substantia nigra pars compacta (snc). |
2008-11-05 |
2023-08-12 |
rat |
| Shyamal H Mehta, John C Morgan, Kapil D Seth. Neuroimaging and transcranial ultrasonography in Parkinson's disease. Current neurology and neuroscience reports. vol 8. issue 4. 2008-10-09. PMID:18590613. |
parkinson's disease is a progressive, widespread, neurodegenerative disease in which the involvement of the dopaminergic neurons of the substantia nigra results in significant dopamine depletion in the striatum. |
2008-10-09 |
2023-08-12 |
Not clear |
| Jianyong Wang, Helen M Duhart, Zengjun Xu, Tucker A Patterson, Glenn D Newport, Syed F Al. Comparison of the time courses of selective gene expression and dopaminergic depletion induced by MPP+ in MN9D cells. Neurochemistry international. vol 52. issue 6. 2008-07-28. PMID:18069091. |
parkinson's disease (pd) is a common neurodegenerative disease characterized by progressive loss of midbrain dopaminergic neurons with unknown etiology. |
2008-07-28 |
2023-08-12 |
Not clear |
| Angela Pignatelli, Ottorino Belluzz. Cholinergic modulation of dopaminergic neurons in the mouse olfactory bulb. Chemical senses. vol 33. issue 4. 2008-07-21. PMID:18209017. |
this modulation of dopaminergic interneurons may be important in the processing of sensory information and may be relevant to understand the mechanisms underlying the olfactory dysfunctions occurring in neurodegenerative diseases affecting the dopaminergic and/or cholinergic systems. |
2008-07-21 |
2023-08-12 |
mouse |
| Barbara Steiner, Christine Winter, Stefan Blumensath, Gesine Paul, Daniel Harnack, Guido Nikkhah, Andreas Kupsc. Survival and functional recovery of transplanted human dopaminergic neurons into hemiparkinsonian rats depend on the cannula size of the implantation instrument. Journal of neuroscience methods. vol 169. issue 1. 2008-06-23. PMID:18241930. |
promising therapeutic strategies for neurodegenerative diseases such as parkinson's disease include replacement of lost striatal dopaminergic neurons by grafting of embryonic mesencephalic cells. |
2008-06-23 |
2023-08-12 |
human |
| Shaik Shavali, Donald A Sen. Synergistic neurotoxic effects of arsenic and dopamine in human dopaminergic neuroblastoma SH-SY5Y cells. Toxicological sciences : an official journal of the Society of Toxicology. vol 102. issue 2. 2008-04-10. PMID:18079140. |
parkinson's disease is an environmentally influenced, neurodegenerative disease of unknown origin that is characterized by the progressive loss of dopaminergic neurons in the substantia nigra pars compacta of the brain. |
2008-04-10 |
2023-08-12 |
human |
| Yi Wang, Sheng Chen, Dehua Yang, Wei-dong L. Stem cell transplantation: a promising therapy for Parkinson's disease. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 2. issue 3. 2008-02-25. PMID:18040857. |
parkinson's disease is one of the most common neurodegenerative diseases caused by the loss of dopaminergic neurons in the substantia nigra pars compacta. |
2008-02-25 |
2023-08-12 |
Not clear |
| Alex Iranzo, Cynthia L Comella, Joan Santamaria, Wolfgang Oerte. Restless legs syndrome in Parkinson's disease and other neurodegenerative diseases of the central nervous system. Movement disorders : official journal of the Movement Disorder Society. vol 22 Suppl 18. 2008-02-14. PMID:17534950. |
the pathophysiology of restless legs syndrome (rls) is associated with central dopaminergic system dysfunction leading to speculations that rls may be common in those neurodegenerative diseases with dopaminergic cell loss. |
2008-02-14 |
2023-08-12 |
Not clear |
| Mario Di Napoli, Imtiaz M Shah, David A Stewar. Molecular pathways and genetic aspects of Parkinson's disease: from bench to bedside. Expert review of neurotherapeutics. vol 7. issue 12. 2008-01-31. PMID:18052765. |
idiopathic parkinson's disease (pd) is a progressive neurodegenerative disease characterized by dopaminergic neuronal loss within the substantia nigra. |
2008-01-31 |
2023-08-12 |
Not clear |
| Justin D Boyd, Haeman Jang, Kennie R Shepherd, Ciaran Faherty, Sally Slack, Yun Jiao, Richard J Smeyn. Response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) differs in mouse strains and reveals a divergence in JNK signaling and COX-2 induction prior to loss of neurons in the substantia nigra pars compacta. Brain research. vol 1175. 2008-01-25. PMID:17884023. |
parkinson's disease (pd) is a neurodegenerative disease whose hallmark pathological features include a selective loss of dopaminergic neurons in the midbrain. |
2008-01-25 |
2023-08-12 |
mouse |
| Jianyong Wang, Zengjun Xu, Hong Fang, Helen M Duhart, Tucker A Patterson, Syed F Al. Gene expression profiling of MPP+-treated MN9D cells: a mechanism of toxicity study. Neurotoxicology. vol 28. issue 5. 2007-12-26. PMID:17475336. |
parkinson's disease (pd) is a common neurodegenerative disease characterized by progressive loss of midbrain dopaminergic neurons with unknown etiology. |
2007-12-26 |
2023-08-12 |
mouse |