| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuki Aoyama, Kazuya Toriumi, Akihiro Mouri, Tomoya Hattori, Eriko Ueda, Akane Shimato, Nami Sakakibara, Yuka Soh, Takayoshi Mamiya, Taku Nagai, Hyoung-Chun Kim, Masayuki Hiramatsu, Toshitaka Nabeshima, Kiyofumi Yamad. Prenatal Nicotine Exposure Impairs the Proliferation of Neuronal Progenitors, Leading to Fewer Glutamatergic Neurons in the Medial Prefrontal Cortex. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 2. 2016-09-20. PMID:26105135. |
prenatal nicotine exposure impairs the proliferation of neuronal progenitors, leading to fewer glutamatergic neurons in the medial prefrontal cortex. |
2016-09-20 |
2023-08-13 |
mouse |
| Yuki Aoyama, Kazuya Toriumi, Akihiro Mouri, Tomoya Hattori, Eriko Ueda, Akane Shimato, Nami Sakakibara, Yuka Soh, Takayoshi Mamiya, Taku Nagai, Hyoung-Chun Kim, Masayuki Hiramatsu, Toshitaka Nabeshima, Kiyofumi Yamad. Prenatal Nicotine Exposure Impairs the Proliferation of Neuronal Progenitors, Leading to Fewer Glutamatergic Neurons in the Medial Prefrontal Cortex. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 2. 2016-09-20. PMID:26105135. |
accordingly, the density of glutamatergic neurons in the medial prefrontal cortex (medial pfc) was reduced, implying glutamatergic dysregulation. |
2016-09-20 |
2023-08-13 |
mouse |
| Carl Björkholm, Kent Jardemark, Björn Schilström, Torgny H Svensso. Ketamine-like effects of a combination of olanzapine and fluoxetine on AMPA and NMDA receptor-mediated transmission in the medial prefrontal cortex of the rat. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 10. 2016-07-12. PMID:26233606. |
preclinical studies indicate that the rapid antidepressant effect of ketamine is dependent on activation of ampa receptors in the medial prefrontal cortex (mpfc) resulting in a prolonged enhancement of glutamatergic transmission in the mpfc. |
2016-07-12 |
2023-08-13 |
rat |
| Jeffrey Burgdorf, Roger A Kroes, Xiao-lei Zhang, Amanda L Gross, Mary Schmidt, Craig Weiss, John F Disterhoft, Ronald M Burch, Patric K Stanton, Joseph R Moska. Rapastinel (GLYX-13) has therapeutic potential for the treatment of post-traumatic stress disorder: Characterization of a NMDA receptor-mediated metaplasticity process in the medial prefrontal cortex of rats. Behavioural brain research. vol 294. 2016-06-14. PMID:26210936. |
since cfe is nmda receptor modulated and neural circuitry in the medial prefrontal cortex (mpfc) regulates both depression and ptsd, studies were undertaken to examine the effects of rapastinel for its therapeutic potential in ptsd and to use rapastinel as a tool to study its underlying glutamatergic mechanisms. |
2016-06-14 |
2023-08-13 |
rat |
| Crystle J Kelly, Mei Huang, Herbert Meltzer, Marco Martin. Reduced Glutamatergic Currents and Dendritic Branching of Layer 5 Pyramidal Cells Contribute to Medial Prefrontal Cortex Deactivation in a Rat Model of Neuropathic Pain. Frontiers in cellular neuroscience. vol 10. 2016-06-02. PMID:27252623. |
reduced glutamatergic currents and dendritic branching of layer 5 pyramidal cells contribute to medial prefrontal cortex deactivation in a rat model of neuropathic pain. |
2016-06-02 |
2023-08-13 |
rat |
| b' C\\xc3\\xa9sar Quiroz, Marco Orr\\xc3\\xba, William Rea, Andr\\xc3\\xa9s Ciudad-Roberts, Gabriel Yepes, Jonathan P Britt, Sergi Ferr\\xc3\\xa. Local Control of Extracellular Dopamine Levels in the Medial Nucleus Accumbens by a Glutamatergic Projection from the Infralimbic Cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 3. 2016-05-27. PMID:26791215.' |
it is generally assumed that infralimbic cortex (ilc) and prelimbic cortex, two adjacent areas of the medial prefrontal cortex (mpfc) in rodents, provide selective excitatory glutamatergic inputs to the nucleus accumbens (nac) shell and core, respectively. |
2016-05-27 |
2023-08-13 |
Not clear |
| F Guida, L Luongo, F Marmo, R Romano, M Iannotta, F Napolitano, C Belardo, I Marabese, A D'Aniello, D De Gregorio, F Rossi, F Piscitelli, R Lattanzi, A de Bartolomeis, A Usiello, V Di Marzo, V de Novellis, S Maion. Palmitoylethanolamide reduces pain-related behaviors and restores glutamatergic synapses homeostasis in the medial prefrontal cortex of neuropathic mice. Molecular brain. vol 8. 2016-04-07. PMID:26260027. |
palmitoylethanolamide reduces pain-related behaviors and restores glutamatergic synapses homeostasis in the medial prefrontal cortex of neuropathic mice. |
2016-04-07 |
2023-08-13 |
mouse |
| F Luo, H Tang, Z-Y Chen. Stimulation of α1-adrenoceptors facilitates GABAergic transmission onto pyramidal neurons in the medial prefrontal cortex. Neuroscience. vol 300. 2016-03-29. PMID:25943480. |
whereas activation of α1-adrenoceptors (α1-ars) modulates glutamatergic transmission, the roles of α1-ars in gabaergic transmission in the medial prefrontal cortex (mpfc) are elusive. |
2016-03-29 |
2023-08-13 |
Not clear |
| Rosemary C Bagot, Eric M Parise, Catherine J Peña, Hong-Xing Zhang, Ian Maze, Dipesh Chaudhury, Brianna Persaud, Roger Cachope, Carlos A Bolaños-Guzmán, Joseph F Cheer, Joseph Cheer, Karl Deisseroth, Ming-Hu Han, Eric J Nestle. Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression. Nature communications. vol 6. 2016-02-29. PMID:25952660. |
the nac receives glutamatergic inputs from the medial prefrontal cortex (mpfc), ventral hippocampus (vhip) and basolateral amygdala (amy). |
2016-02-29 |
2023-08-13 |
mouse |
| Mohammad-Reza Zarrindast, Fatemeh Khakpa. The Modulatory Role of Dopamine in Anxiety-like Behavior. Archives of Iranian medicine. vol 18. issue 9. 2016-02-01. PMID:26317601. |
the activity of dopaminergic system is modulated by several neurotransmitters, including glutamatergic neurons from the medial prefrontal cortex (mpfc), gabaergic fibers from the nucleus accumbens (nac) as well as the ventral pallidum and cholinergic fibers from the pedunculopontine nucleus and the laterodorsal tegmental nucleus. |
2016-02-01 |
2023-08-13 |
Not clear |
| Ida Fredriksson, Nitya Jayaram-Lindström, Malin Wirf, Erik Nylander, Erica Nyström, Kent Jardemark, Pia Steenslan. Evaluation of guanfacine as a potential medication for alcohol use disorder in long-term drinking rats: behavioral and electrophysiological findings. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 5. 2015-12-31. PMID:25359257. |
in addition, guanfacine's ability to regulate glutamatergic neurotransmission was evaluated through electrophysiological recordings in medial prefrontal cortex (mpfc) slices prepared from long-term drinking rats (and alcohol-naive controls) that had received three daily guanfacine (0.6 mg/kg/day) or vehicle injections in vivo. |
2015-12-31 |
2023-08-13 |
rat |
| Carl Björkholm, Olivia Frånberg, Anna Malmerfelt, Monica M Marcus, Åsa Konradsson-Geuken, Björn Schilström, Kent Jardemark, Torgny H Svensso. Adjunctive treatment with asenapine augments the escitalopram-induced effects on monoaminergic outflow and glutamatergic neurotransmission in the medial prefrontal cortex of the rat. The international journal of neuropsychopharmacology. vol 18. issue 3. 2015-10-27. PMID:25522408. |
adjunctive treatment with asenapine augments the escitalopram-induced effects on monoaminergic outflow and glutamatergic neurotransmission in the medial prefrontal cortex of the rat. |
2015-10-27 |
2023-08-13 |
rat |
| Devesh Mishra, Nicholas R Harrison, Carolina B Gonzales, Björn Schilström, Åsa Konradsson-Geuke. Effects of age and acute ethanol on glutamatergic neurotransmission in the medial prefrontal cortex of freely moving rats using enzyme-based microelectrode amperometry. PloS one. vol 10. issue 4. 2015-10-16. PMID:25927237. |
effects of age and acute ethanol on glutamatergic neurotransmission in the medial prefrontal cortex of freely moving rats using enzyme-based microelectrode amperometry. |
2015-10-16 |
2023-08-13 |
rat |
| Lucia Caffino, Francesca Calabrese, Giuseppe Giannotti, Alessandro Barbon, Michel M M Verheij, Giorgio Racagni, Fabio Fumagall. Stress rapidly dysregulates the glutamatergic synapse in the prefrontal cortex of cocaine-withdrawn adolescent rats. Addiction biology. vol 20. issue 1. 2015-08-24. PMID:24102978. |
critical determinants of glutamatergic homeostasis were measured in the medial prefrontal cortex (mpfc) whereas circulating corticosterone levels were measured in the plasma. |
2015-08-24 |
2023-08-12 |
rat |
| Bart R Lubbers, Yvar van Mourik, Dustin Schetters, August B Smit, Taco J De Vries, Sabine Spijke. Prefrontal gamma-aminobutyric acid type A receptor insertion controls cue-induced relapse to nicotine seeking. Biological psychiatry. vol 76. issue 9. 2015-06-08. PMID:24631130. |
the objective of this study was to elucidate the role of medial prefrontal cortex (mpfc) glutamatergic and gamma-aminobutyric acid (gaba)ergic receptors in controlling relapse to nicotine seeking. |
2015-06-08 |
2023-08-12 |
Not clear |
| Masanori Ohashi, Akiyoshi Saitoh, Misa Yamada, Jun-Ichiro Oka, Mitsuhiko Yamad. Riluzole in the prelimbic medial prefrontal cortex attenuates veratrine-induced anxiety-like behaviors in mice. Psychopharmacology. vol 232. issue 2. 2015-06-03. PMID:25127925. |
we previously demonstrated in mice that the activation of prelimbic medial prefrontal cortex (pl) with the sodium channel activator veratrine induces anxiety-like behaviors via nmda receptor-mediated glutamatergic neurotransmission. |
2015-06-03 |
2023-08-13 |
mouse |
| Christopher Galvin, Ipe Nina. Regulation of the mouse medial prefrontal cortical synapses by endogenous estradiol. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 9. 2015-03-02. PMID:24608267. |
to understand the synaptic basis of the effect of endogenous estradiol on fear extinction, we studied glutamatergic transmission and plasticity in the infralimbic medial prefrontal cortex (il-mpfc), a brain region crucial for the regulation of fear extinction. |
2015-03-02 |
2023-08-12 |
mouse |
| Akiyoshi Saitoh, Masanori Ohashi, Satoshi Suzuki, Mai Tsukagoshi, Azusa Sugiyama, Misa Yamada, Jun-Ichiro Oka, Masatoshi Inagaki, Mitsuhiko Yamad. Activation of the prelimbic medial prefrontal cortex induces anxiety-like behaviors via N-Methyl-D-aspartate receptor-mediated glutamatergic neurotransmission in mice. Journal of neuroscience research. vol 92. issue 8. 2015-02-21. PMID:24752881. |
activation of the prelimbic medial prefrontal cortex induces anxiety-like behaviors via n-methyl-d-aspartate receptor-mediated glutamatergic neurotransmission in mice. |
2015-02-21 |
2023-08-13 |
mouse |
| Fei Luo, Si-Hai Li, Hua Tang, Wei-Ke Deng, Yu Zhang, Ying Li. Phenylephrine enhances glutamate release in the medial prefrontal cortex through interaction with N-type Ca2+ channels and release machinery. Journal of neurochemistry. vol 132. issue 1. 2015-02-19. PMID:25196067. |
a recent study in our laboratory showed that α1 -ars stimulation enhances glutamatergic transmission via both pre- and post-synaptic mechanisms in layer v/vi pyramidal cells of the rat medial prefrontal cortex (mpfc). |
2015-02-19 |
2023-08-13 |
rat |
| Fei Luo, Si-Hai Li, Hua Tang, Wei-Ke Deng, Yu Zhang, Ying Li. Phenylephrine enhances glutamate release in the medial prefrontal cortex through interaction with N-type Ca2+ channels and release machinery. Journal of neurochemistry. vol 132. issue 1. 2015-02-19. PMID:25196067. |
alpha1 -adrenoceptor (α1 -ars) stimulation has been reported to enhance glutamatergic transmission in layer v/vi pyramidal neurons of the rat medial prefrontal cortex (mpfc). |
2015-02-19 |
2023-08-13 |
rat |