| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fei Luo, Nan-Nan Guo, Si-Hai Li, Hua Tang, Ying Liu, Yu Zhan. Reduction of glutamate release probability and the number of releasable vesicles are required for suppression of glutamatergic transmission by β1-adrenoceptors in the medial prefrontal cortex. Neuropharmacology. vol 83. 2015-01-29. PMID:24727211. |
reduction of glutamate release probability and the number of releasable vesicles are required for suppression of glutamatergic transmission by β1-adrenoceptors in the medial prefrontal cortex. |
2015-01-29 |
2023-08-13 |
Not clear |
| Yao-Ying Ma, Brian R Lee, Xiusong Wang, Changyong Guo, Lei Liu, Ranji Cui, Yan Lan, Judith J Balcita-Pedicino, Marina E Wolf, Susan R Sesack, Yavin Shaham, Oliver M Schlüter, Yanhua H Huang, Yan Don. Bidirectional modulation of incubation of cocaine craving by silent synapse-based remodeling of prefrontal cortex to accumbens projections. Neuron. vol 83. issue 6. 2015-01-21. PMID:25199705. |
glutamatergic projections from the medial prefrontal cortex (mpfc) to nucleus accumbens (nac) contribute to cocaine relapse. |
2015-01-21 |
2023-08-13 |
rat |
| Renato Leonardo de Freitas, Carlos José Salgado-Rohner, Audrey Francisco Biagioni, Priscila Medeiros, Jaime Eduardo Cecílio Hallak, José Alexandre S Crippa, Norberto Cysne Coimbr. NMDA and AMPA/kainate glutamatergic receptors in the prelimbic medial prefrontal cortex modulate the elaborated defensive behavior and innate fear-induced antinociception elicited by GABAA receptor blockade in the medial hypothalamus. Cerebral cortex (New York, N.Y. : 1991). vol 24. issue 6. 2014-12-16. PMID:23349224. |
nmda and ampa/kainate glutamatergic receptors in the prelimbic medial prefrontal cortex modulate the elaborated defensive behavior and innate fear-induced antinociception elicited by gabaa receptor blockade in the medial hypothalamus. |
2014-12-16 |
2023-08-12 |
rat |
| Wen-Yan Han, Ping Du, Shi-Yuan Fu, Fang Wang, Ming Song, Chun-Fu Wu, Jing-Yu Yan. Oxytocin via its receptor affects restraint stress-induced methamphetamine CPP reinstatement in mice: Involvement of the medial prefrontal cortex and dorsal hippocampus glutamatergic system. Pharmacology, biochemistry, and behavior. vol 119. 2014-11-14. PMID:24269543. |
oxytocin via its receptor affects restraint stress-induced methamphetamine cpp reinstatement in mice: involvement of the medial prefrontal cortex and dorsal hippocampus glutamatergic system. |
2014-11-14 |
2023-08-12 |
mouse |
| Tamara Romón, Anna M Planas, Albert Adel. Blockade of MK-801-induced heat shock protein 72/73 in rat brain by antipsychotic and monoaminergic agents targeting D2, 5-HT1A, 5-HT2A and α1-adrenergic receptors. CNS & neurological disorders drug targets. vol 13. issue 1. 2014-10-08. PMID:24040788. |
in rats, these drugs induce a behavioral syndrome (characterized by hyperlocomotion and stereotypies), an enhanced glutamatergic transmission in the medial prefrontal cortex, and damage to retrosplenial cortical neurons in adult rats, which was measured as the induction of the stress protein 72/73 kda heat shock protein (hsp72/73). |
2014-10-08 |
2023-08-12 |
rat |
| Tiffany D Rogers, Price E Dickson, Eric McKimm, Detlef H Heck, Dan Goldowitz, Charles D Blaha, Guy Mittlema. Reorganization of circuits underlying cerebellar modulation of prefrontal cortical dopamine in mouse models of autism spectrum disorder. Cerebellum (London, England). vol 12. issue 4. 2014-03-03. PMID:23436049. |
we previously reported that cerebellar activity modulates dopamine release in the mouse medial prefrontal cortex (mpfc) via two distinct pathways: (1) cerebellum to mpfc via dopaminergic projections from the ventral tegmental area (vta) and (2) cerebellum to mpfc via glutamatergic projections from the mediodorsal and ventrolateral thalamus (thn md and vl). |
2014-03-03 |
2023-08-12 |
mouse |
| Mary Kay Lobo, Samir Zaman, Diane M Damez-Werno, Ja Wook Koo, Rosemary C Bagot, Jennifer A DiNieri, Alexandria Nugent, Eric Finkel, Dipesh Chaudhury, Ramesh Chandra, Efrain Riberio, Jacqui Rabkin, Ezekiell Mouzon, Roger Cachope, Joseph F Cheer, Ming-Hu Han, David M Dietz, David W Self, Yasmin L Hurd, Vincent Vialou, Eric J Nestle. ΔFosB induction in striatal medium spiny neuron subtypes in response to chronic pharmacological, emotional, and optogenetic stimuli. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 47. 2014-01-21. PMID:24259563. |
to explore the circuit-mediated induction of Δfosb in striatum, we use optogenetics to enhance activity in limbic brain regions that send synaptic inputs to nac; these regions include the ventral tegmental area and several glutamatergic afferent regions: medial prefrontal cortex, amygdala, and ventral hippocampus. |
2014-01-21 |
2023-08-12 |
mouse |
| Matthew Hearing, Lydia Kotecki, Ezequiel Marron Fernandez de Velasco, Ana Fajardo-Serrano, Hee Jung Chung, Rafael Luján, Kevin Wickma. Repeated cocaine weakens GABA(B)-Girk signaling in layer 5/6 pyramidal neurons in the prelimbic cortex. Neuron. vol 80. issue 1. 2013-12-23. PMID:24094109. |
repeated cocaine exposure triggers adaptations in layer 5/6 glutamatergic neurons in the medial prefrontal cortex (mpfc) that promote behavioral sensitization and drug-seeking behavior. |
2013-12-23 |
2023-08-12 |
Not clear |
| Alice Dobi, Simone B Sartori, Daniela Busti, Herman Van der Putten, Nicolas Singewald, Ryuichi Shigemoto, Francesco Ferragut. Neural substrates for the distinct effects of presynaptic group III metabotropic glutamate receptors on extinction of contextual fear conditioning in mice. Neuropharmacology. vol 66. 2013-07-02. PMID:22643400. |
in particular, mglu7a receptors were primarily onto glutamatergic afferents arising from the ba or midline thalamic nuclei, but not the medial prefrontal cortex (mpfc), as revealed by combined anterograde tracing and pre-embedding electron microscopy. |
2013-07-02 |
2023-08-12 |
mouse |
| Somayeh Shahidani, Parham Reisi, Naser Naghdi, HojjatAllah Alaei, Effat Ramshin. Lesion of medial prefrontal cortex reduces morphine-induced extracellular dopamine level in the ventral tegmental area: a microdialysis study in rats. Pharmacology, biochemistry, and behavior. vol 102. issue 1. 2013-03-14. PMID:22741176. |
the medial prefrontal cortex (mpfc), a part of the mesocorticolimbic dopaminergic system, receives dopaminergic projections from vta; and in turn, sends glutamatergic projections to both vta and na. |
2013-03-14 |
2023-08-12 |
rat |
| Shigenobu Tod. [The role of the striatum in addiction]. Brain and nerve = Shinkei kenkyu no shinpo. vol 64. issue 8. 2012-10-18. PMID:22868882. |
second, after providing a brief introduction to unmanageable maladaptive behaviors in addiction that may be attributable to the impairments of the medial prefrontal cortex, anterior cingulate cortex, and orbitofrontal cortex, i emphasize the roles of glutamatergic inputs projecting from these frontal areas to the nucleus accumbens in cue-primed reinstatement of drug-seeking and impaired neuronal plasticity. |
2012-10-18 |
2023-08-12 |
human |
| Kristin M Timmer, Jeffery D Stekete. Examination of a role for metabotropic glutamate receptor 5 in the medial prefrontal cortex in cocaine sensitization in rats. Psychopharmacology. vol 221. issue 1. 2012-09-25. PMID:22147256. |
glutamatergic projection neurons in the medial prefrontal cortex (mpfc) are hyperexcitable in cocaine-sensitized animals, resulting in increased excitatory output to addiction-associated regions such as the ventral tegmental area (vta) and nucleus accumbens. |
2012-09-25 |
2023-08-12 |
rat |
| M Behnam Ghasemzadeh, Preethi Vasudevan, Chad Giles, Anthony Purgianto, Chad Seubert, John R Mantsc. Glutamatergic plasticity in medial prefrontal cortex and ventral tegmental area following extended-access cocaine self-administration. Brain research. vol 1413. 2012-06-12. PMID:21855055. |
glutamatergic plasticity in medial prefrontal cortex and ventral tegmental area following extended-access cocaine self-administration. |
2012-06-12 |
2023-08-12 |
rat |
| Y Wang, J Liu, Z H Gui, U Ali, L L Fan, C Hou, T Wang, L Chen, Q L. α2-Adrenoceptor regulates the spontaneous and the GABA/glutamate modulated firing activity of the rat medial prefrontal cortex pyramidal neurons. Neuroscience. vol 182. 2012-05-31. PMID:21402127. |
the spontaneous and event-related firing activity of the medial prefrontal cortex (mpfc) pyramidal neurons are modulated mainly by glutamatergic inputs and gabaergic afferents. |
2012-05-31 |
2023-08-12 |
rat |
| Nilson C Ferreira-Junior, Alessandra G Fedoce, Fernando H F Alves, Fernando M A Corrêa, Leonardo B M Resste. Medial prefrontal cortex endocannabinoid system modulates baroreflex activity through CB(1) receptors. American journal of physiology. Regulatory, integrative and comparative physiology. vol 302. issue 7. 2012-05-25. PMID:22204950. |
eur j neurosci 23: 481-488, 2006) have shown that glutamatergic synapses in the ventral portion of the medial prefrontal cortex (vmpfc) modulate baroreflex activity. |
2012-05-25 |
2023-08-12 |
rat |
| Kun Liu, Jeffery D Stekete. Repeated exposure to cocaine alters medial prefrontal cortex dopamine D₂-like receptor modulation of glutamate and dopamine neurotransmission within the mesocorticolimbic system. Journal of neurochemistry. vol 119. issue 2. 2011-11-15. PMID:21692802. |
these findings indicate that the expression of sensitization to cocaine is associated with altered modulation of mesocorticolimbic glutamatergic transmission at the level of the medial prefrontal cortex. |
2011-11-15 |
2023-08-12 |
rat |
| Ipe Nina. Oxytocin suppresses basal glutamatergic transmission but facilitates activity-dependent synaptic potentiation in the medial prefrontal cortex. Journal of neurochemistry. vol 119. issue 2. 2011-11-15. PMID:21848811. |
oxytocin suppresses basal glutamatergic transmission but facilitates activity-dependent synaptic potentiation in the medial prefrontal cortex. |
2011-11-15 |
2023-08-12 |
Not clear |
| Garret D Stuber, Dennis R Sparta, Alice M Stamatakis, Wieke A van Leeuwen, Juanita E Hardjoprajitno, Saemi Cho, Kay M Tye, Kimberly A Kempadoo, Feng Zhang, Karl Deisseroth, Antonello Bonc. Excitatory transmission from the amygdala to nucleus accumbens facilitates reward seeking. Nature. vol 475. issue 7356. 2011-08-30. PMID:21716290. |
moreover, although optical stimulation of glutamatergic fibres from the medial prefrontal cortex to the nac also elicited reliable excitatory synaptic responses, optical self-stimulation behaviour was not observed by activation of this pathway. |
2011-08-30 |
2023-08-12 |
mouse |
| Heath D Schmidt, Katie R Famous, R C Pierc. The limbic circuitry underlying cocaine seeking encompasses the PPTg/LDT. The European journal of neuroscience. vol 30. issue 7. 2010-01-18. PMID:19788581. |
the direct glutamatergic projection from the medial prefrontal cortex (mpfc) to the nucleus accumbens plays a critical role in mediating the reinstatement of cocaine seeking behavior. |
2010-01-18 |
2023-08-12 |
rat |
| Kent E Jardemark, Asa Konradsson, Björn Schilström, Monica M Marcus, Torgny H Svensso. Differential effects of topiramate on prefrontal glutamatergic transmission when combined with raclopride or clozapine. Synapse (New York, N.Y.). vol 63. issue 10. 2009-10-26. PMID:19582782. |
both dopaminergic and glutamatergic transmissions in the medial prefrontal cortex (mpfc) are facilitated by atypical, but not typical, apds, which is thought to improve negative symptoms and cognitive dysfunction in schizophrenia. |
2009-10-26 |
2023-08-12 |
rat |