| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dianna L Hynds, Nagarathnamma Rangappa, Julia Ter Beest, Diane M Snow, Alexander G Rabchevsk. Microglia enhance dorsal root ganglion outgrowth in Schwann cell cultures. Glia. vol 46. issue 2. 2004-05-28. PMID:15042588. |
we sought to determine whether the addition of microglia or microglia-derived secretory products alters drg axon regrowth upon cultures of sc. |
2004-05-28 |
2023-08-12 |
rat |
| Dianna L Hynds, Nagarathnamma Rangappa, Julia Ter Beest, Diane M Snow, Alexander G Rabchevsk. Microglia enhance dorsal root ganglion outgrowth in Schwann cell cultures. Glia. vol 46. issue 2. 2004-05-28. PMID:15042588. |
rat drg explants were grown on monolayers consisting of either sc, microglia, sc exposed to microglia-conditioned medium (mcm), or co-cultures with different relative concentrations of microglia. |
2004-05-28 |
2023-08-12 |
rat |
| Dianna L Hynds, Nagarathnamma Rangappa, Julia Ter Beest, Diane M Snow, Alexander G Rabchevsk. Microglia enhance dorsal root ganglion outgrowth in Schwann cell cultures. Glia. vol 46. issue 2. 2004-05-28. PMID:15042588. |
these results show that microglia or their secreted products can augment sc-mediated drg regrowth in vitro, indicating that co-grafting sc with microglia provides a novel approach to augment sensory fiber regeneration after spinal cord injury. |
2004-05-28 |
2023-08-12 |
rat |
| Shan-Xue Jin, Zhi-Ye Zhuang, Clifford J Woolf, Ru-Rong J. p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 10. 2003-06-25. PMID:12764087. |
p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain. |
2003-06-25 |
2023-08-12 |
rat |
| Shan-Xue Jin, Zhi-Ye Zhuang, Clifford J Woolf, Ru-Rong J. p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 10. 2003-06-25. PMID:12764087. |
because the reduction in neuropathic pain by p38 inhibition occurs before the appearance of p38 activation in drg neurons, p38 activation in spinal cord microglia is likely to have a substantial role in the earliest phase of neuropathic pain. |
2003-06-25 |
2023-08-12 |
rat |
| Shan-Xue Jin, Zhi-Ye Zhuang, Clifford J Woolf, Ru-Rong J. p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 10. 2003-06-25. PMID:12764087. |
coactivation of p38 in drg neurons and spinal microglia may contribute to later phases of neuropathic pain. |
2003-06-25 |
2023-08-12 |
rat |
| J Robertson, J M Beaulieu, M M Doroudchi, H D Durham, J P Julien, W E Mushynsk. Apoptotic death of neurons exhibiting peripherin aggregates is mediated by the proinflammatory cytokine tumor necrosis factor-alpha. The Journal of cell biology. vol 155. issue 2. 2001-12-04. PMID:11604419. |
apoptosis of drg neurons containing peripherin aggregates was dependent on the proinflammatory central nervous system environment of spinal cultures, rich in activated microglia, and required tnf-alpha. |
2001-12-04 |
2023-08-12 |
mouse |
| J C Petruska, W J Streit, R D Johnso. Localization of unmyelinated axons in rat skin and mucocutaneous tissue utilizing the isolectin GS-I-B4. Somatosensory & motor research. vol 14. issue 1. 1997-10-01. PMID:9241725. |
the alpha-d-galactose specific isolectin i-b4 from griffonia simplicifolia (gs-i-b4) labels cns microglia and certain peripheral neurons, including a subpopulation of small dark, type b dorsal root ganglion cells, some post-ganglionic sympathetic axons, and nearly all peripheral gustatory axons. |
1997-10-01 |
2023-08-12 |
rat |
| B P He, S S Tay, S K Leon. Microglia responses in the CNS following sciatic nerve transection in C57BL/Wld(s) and BALB/c mice. Experimental neurology. vol 146. issue 2. 1997-09-19. PMID:9270072. |
the observations showed that in both strains of mice there was no delayed microglia response around lesioned motoneurons and around the central processes of the dorsal root ganglion cells after sciatic neurectomy in the adult. |
1997-09-19 |
2023-08-12 |
mouse |
| S K Ludwin, S Szuche. Myelination by mature ovine oligodendrocytes in vivo and in vitro: evidence that different steps in the myelination process are independently controlled. Glia. vol 8. issue 4. 1993-11-08. PMID:8406679. |
it is possible that the failure of ovine oligodendrocytes to myelinate drg axons is due either to the relatively low number of supporting glial cells, such as astrocytes or microglia which may be necessary for satisfactory myelination, or that some other factor in the microenvironment is lacking; in any event, these results point to the complexity of oligodendrocyte-axon interactions. |
1993-11-08 |
2023-08-12 |
mouse |
| M Nagao, H Kamo, I Akiguchi, J Kimur. Soybean agglutinin binds commonly to a subpopulation of small-diameter neurons in dorsal root ganglion, vascular endothelium and microglia in human spinal cord. Neuroscience letters. vol 142. issue 2. 1993-01-06. PMID:1454206. |
soybean agglutinin binds commonly to a subpopulation of small-diameter neurons in dorsal root ganglion, vascular endothelium and microglia in human spinal cord. |
1993-01-06 |
2023-08-11 |
human |
| M Nagao, H Kamo, I Akiguchi, J Kimur. Soybean agglutinin binds commonly to a subpopulation of small-diameter neurons in dorsal root ganglion, vascular endothelium and microglia in human spinal cord. Neuroscience letters. vol 142. issue 2. 1993-01-06. PMID:1454206. |
vascular endothelium, drg neurons and microglia do not originate from the neural tube, but penetrate into the neural tube in the embryonic stage and thereafter are located in the spinal cord. |
1993-01-06 |
2023-08-11 |
human |
| P G Kennedy, R P Lisak, M C Raf. Cell type-specific markers for human glial and neuronal cells in culture. Laboratory investigation; a journal of technical methods and pathology. vol 43. issue 4. 1981-02-26. PMID:6160316. |
astrocytes were identified by the intracellular expression of glial fibrillary acidic protein, oligodendrocytes by the cell surface expression of galactocerebroside, dorsal root ganglion neurons by their ability to bind tetanus toxin at their surface, and macrophages (including microglia) by cell surface fc receptors and their phagocytic properties. |
1981-02-26 |
2023-08-12 |
human |