All Relations between microglial cell and mesencephalon
Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
K Unsicker, C Suter-Crazzalora, K Krieglstei. Growth factor function in the development and maintenance of midbrain dopaminergic neurons: concepts, facts and prospects for TGF-beta. Ciba Foundation symposium. vol 196. 1997-01-13. PMID:8866128. |
on the basis of their localization, putative sources and mechanisms of actions, such growth factors fall into several categories: (i) local factors within the midbrain influencing proliferation, transmitter phenotype, migration, positioning and neurite growth of stem cells and early neurons; (ii) factors acting retrogradely from the striatum, which are responsible for intrastriatal sprouting and navigation of newly arrived axons as well as life-long maintenance of the dopaminergic nigrostriatal connection; (iii) factors coming into play when the system is toxically impaired; (iv) factors directly acting on dopaminergic neurons; and (v) factors provided by cytokinestimulated astroglia, microglia and neurons affecting dopaminergic neurons anterogradely. |
1997-01-13 |
2023-08-12 |
Not clear |
T Wierzba-Bobrowicz, E Gwiazda, Z Poszwińsk. Morphological study of microglia in human mesencephalon during the development and aging. Folia neuropathologica. vol 33. issue 2. 1996-09-09. PMID:8705275. |
morphological study of microglia in human mesencephalon during the development and aging. |
1996-09-09 |
2023-08-12 |
human |
K Nagata, N Takei, K Nakajima, H Saito, S Kohsak. Microglial conditioned medium promotes survival and development of cultured mesencephalic neurons from embryonic rat brain. Journal of neuroscience research. vol 34. issue 3. 1993-04-16. PMID:8095989. |
these results suggest that mic-cm enhances survival or maturation of th-positive neurons present in cultures of the embryonic mesencephalon and that these neurotrophic effects may be due to a diffusible factor(s) from microglia. |
1993-04-16 |
2023-08-12 |
rat |
I A Goodbrand, R M Gaz. Microglia in tadpoles of Xenopus laevis: normal distribution and the response to optic nerve injury. Anatomy and embryology. vol 184. issue 1. 1991-11-05. PMID:1928746. |
in normal animals microglia are sparsely but widely distributed throughout the retina, optic nerve, diencephalon and mesencephalon (other regions were not examined). |
1991-11-05 |
2023-08-11 |
xenopus_laevis |
K Kure, K M Weidenheim, W D Lyman, D W Dickso. Morphology and distribution of HIV-1 gp41-positive microglia in subacute AIDS encephalitis. Pattern of involvement resembling a multisystem degeneration. Acta neuropathologica. vol 80. issue 4. 1990-12-04. PMID:2239151. |
besides immunoreactive macrophages and multinucleated cells, gp41-positive microglia with various morphological alterations were abundant in the deep cerebral gray matter, ventral midbrain and dentate nucleus. |
1990-12-04 |
2023-08-11 |
Not clear |