| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daniela Zantomio, Gursharan Chana, Liliana Laskaris, Renee Testa, Ian Everall, Christos Pantelis, Efstratios Skafida. Convergent evidence for mGluR5 in synaptic and neuroinflammatory pathways implicated in ASD. Neuroscience and biobehavioral reviews. vol 52. 2015-12-30. PMID:25704074. |
evidence for neuroinflammation in asd is supported by increase in pro-inflammatory cytokines in the blood and cerebrospinal fluid (csf) and increased number and activation of microglia in postmortem dorsolateral prefrontal cortex (dlpfc). |
2015-12-30 |
2023-08-13 |
mouse |
| Nikita N Burke, Daniel M Kerr, Orla Moriarty, David P Finn, Michelle Roch. Minocycline modulates neuropathic pain behaviour and cortical M1-M2 microglial gene expression in a rat model of depression. Brain, behavior, and immunity. vol 42. 2015-12-14. PMID:24994592. |
in comparison, the expression of the m2 microglia marker (mrc2) and anti-inflammatory cytokine il-10 was increased, as were il-1β, il-6 and socs3, in the prefrontal cortex of ob-snl animals following chronic minocycline. |
2015-12-14 |
2023-08-13 |
rat |
| Iris B Hovens, Barbara L van Leeuwen, Csaba Nyakas, Erik Heineman, Eddy A van der Zee, Regien G Schoemake. Postoperative cognitive dysfunction and microglial activation in associated brain regions in old rats. Neurobiology of learning and memory. vol 118. 2015-11-10. PMID:25460037. |
the number and morphology of microglia were analyzed in the hippocampus, prefrontal cortex, striatum and amygdala on postoperative day 14. |
2015-11-10 |
2023-08-13 |
rat |
| Ying Pan, Xu-Yang Chen, Qing-Yu Zhang, Ling-Dong Kon. Microglial NLRP3 inflammasome activation mediates IL-1β-related inflammation in prefrontal cortex of depressive rats. Brain, behavior, and immunity. vol 41. 2015-06-09. PMID:24859041. |
the increased co-location of nlrp3 and ionized calcium binding adaptor molecule 1 (iba1) protein expression supported that microglia in glial cells was the primary contributor for cums-induced pfc nlrp3 inflammasome activation in rats. |
2015-06-09 |
2023-08-13 |
rat |
| Guangying Luo, Shaolin Wang, Zhigang Li, Ruifen Wei, Lianjie Zhang, Huanhuan Liu, Chong Wang, Ruiyan Niu, Jundong Wan. Maternal bisphenol a diet induces anxiety-like behavior in female juvenile with neuroimmune activation. Toxicological sciences : an official journal of the Society of Toxicology. vol 140. issue 2. 2015-03-30. PMID:24824810. |
therefore, we conclude that mbd induces excessive anxiety-like behavior in female juvenile with elevated tnf-α and il-6 levels, as well as activated microglia and astrocyte in pfc. |
2015-03-30 |
2023-08-13 |
mouse |
| Madeleine Hinwood, Ross J Tynan, Janine L Charnley, Sarah B Beynon, Trevor A Day, F Rohan Walke. Chronic stress induced remodeling of the prefrontal cortex: structural re-organization of microglia and the inhibitory effect of minocycline. Cerebral cortex (New York, N.Y. : 1991). vol 23. issue 8. 2014-02-26. PMID:22710611. |
chronic stress induced remodeling of the prefrontal cortex: structural re-organization of microglia and the inhibitory effect of minocycline. |
2014-02-26 |
2023-08-12 |
rat |
| Yue Hou, Hongli Zhang, Guanbo Xie, Xinyue Cao, Yanan Zhao, Yang Liu, Zhihao Mao, Jingyu Yang, Chunfu W. Neuronal injury, but not microglia activation, is associated with ketamine-induced experimental schizophrenic model in mice. Progress in neuro-psychopharmacology & biological psychiatry. vol 45. 2014-02-26. PMID:23603358. |
the results of immunohistochemistry demonstrated that microglia in the prefrontal cortex and hippocampus were not affected after acute or repeated administration of ketamine. |
2014-02-26 |
2023-08-12 |
mouse |
| M Hinwood, J Morandini, T A Day, F R Walke. Evidence that microglia mediate the neurobiological effects of chronic psychological stress on the medial prefrontal cortex. Cerebral cortex (New York, N.Y. : 1991). vol 22. issue 6. 2013-03-11. PMID:21878486. |
these results suggest a role for microglia in mediating the effects of stress on pfc neuronal function and pfc-regulated behavior. |
2013-03-11 |
2023-08-12 |
Not clear |
| Jun Lu, Dong-mei Wu, Yuan-lin Zheng, Bin Hu, Zi-feng Zhang, Qin Ye, Chan-min Liu, Qun Shan, Yong-jian Wan. Ursolic acid attenuates D-galactose-induced inflammatory response in mouse prefrontal cortex through inhibiting AGEs/RAGE/NF-κB pathway activation. Cerebral cortex (New York, N.Y. : 1991). vol 20. issue 11. 2011-08-08. PMID:20133359. |
furthermore, the results also showed that ua significantly reduced the number of activated microglia cells and astrocytes, decreased the expression of cd11b and glial fibrillary acidic protein, downregulated the expression of inos and cox-2, and decreased interleukin (il)-1β, il-6, and tumor necrosis factor-α levels in the prefrontal cortex of d-gal-treated mice. |
2011-08-08 |
2023-08-12 |
mouse |
| Eric S Wohleb, Mark L Hanke, Angela W Corona, Nicole D Powell, La'Tonia M Stiner, Michael T Bailey, Randy J Nelson, Jonathan P Godbout, John F Sherida. β-Adrenergic receptor antagonism prevents anxiety-like behavior and microglial reactivity induced by repeated social defeat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 17. 2011-06-24. PMID:21525267. |
repeated social defeat also increased the presence of deramified microglia in the medial amygdala, prefrontal cortex, and hippocampus. |
2011-06-24 |
2023-08-12 |
mouse |
| Linda Jansson, Malin Wennström, Aki Johanson, Anders Tingströ. Glial cell activation in response to electroconvulsive seizures. Progress in neuro-psychopharmacology & biological psychiatry. vol 33. issue 7. 2009-11-17. PMID:19540297. |
ecs-induced changes in the morphology and expression of markers typical for reactive microglia, astrocytes and ng2+ glial cells were analyzed immunohistochemically in prefrontal cortex, hippocampus, amygdala, hypothalamus, piriform cortex and entorhinal cortex. |
2009-11-17 |
2023-08-12 |
rat |
| Fuxing Zhang, Kujumon I Vadakkan, Susan S Kim, Long-Jun Wu, Yuze Shang, Min Zhu. Selective activation of microglia in spinal cord but not higher cortical regions following nerve injury in adult mouse. Molecular pain. vol 4. 2008-07-08. PMID:18423014. |
in contrast, microglia was not activated in supraspinal regions of the cns, including the anterior cingulate cortex (acc), prefrontal cortex (pfc), primary and secondary somatosensory cortex (s1 and s2), insular cortex (ic), amygdala, hippocampus, periaqueductal gray (pag) and rostral ventromedial medulla (rvm). |
2008-07-08 |
2023-08-12 |
mouse |
| Chad J Reissig, Richard A Rabin, Jerrold C Winter, Cynthia A Dlugo. d-LSD-induced c-Fos expression occurs in a population of oligodendrocytes in rat prefrontal cortex. European journal of pharmacology. vol 583. issue 1. 2008-05-27. PMID:18262520. |
the present study demonstrates that d-lsd induced expression of c-fos in the prefrontal cortex occurs in subpopulations of neurons and in oligodendrocytes, but not in pyramidal neurons, astrocytes, and microglia. |
2008-05-27 |
2023-08-12 |
rat |
| Rocio E Gonzalez-Castañeda, Estela Adriana Castellanos-Alvarado, Maria Rosa Flores-Marquez, Oscar Gonzalez-Perez, Sonia Luquin, Joaquin Garcia-Estrada, Cesar Ramos-Remu. Deflazacort induced stronger immunosuppression than expected. Clinical rheumatology. vol 26. issue 6. 2007-07-31. PMID:16738843. |
the index of degenerated neurons and the number and cytoplasmic transformation of astrocytes and microglia cells were evaluated in the prefrontal cortex, ca1, and ca3 hippocampus. |
2007-07-31 |
2023-08-12 |
rat |
| Matthew Whiteman, Nam Sang Cheung, Yi-Zhun Zhu, Siew Hwa Chu, Jia Ling Siau, Boon Seng Wong, Jeffrey S Armstrong, Philip K Moor. Hydrogen sulphide: a novel inhibitor of hypochlorous acid-mediated oxidative damage in the brain? Biochemical and biophysical research communications. vol 326. issue 4. 2005-02-18. PMID:15607739. |
levels of myeloperoxidase (mpo), an enzyme that catalyses the formation of the oxidant hypochlorous acid (hocl), are elevated in the prefrontal cortex, hippocampal microglia, and neurons of ad patients where mpo co-localised with beta-amyloid plaques. |
2005-02-18 |
2023-08-12 |
human |