| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kelsea R Gildawie, Rodrigo Orso, Shayna Peterzell, Vanessa Thompson, Heather C Brenhous. Sex differences in prefrontal cortex microglia morphology: Impact of a two-hit model of adversity throughout development. Neuroscience letters. vol 738. 2021-05-17. PMID:32927000. |
sex differences in prefrontal cortex microglia morphology: impact of a two-hit model of adversity throughout development. |
2021-05-17 |
2023-08-13 |
rat |
| Kelsea R Gildawie, Rodrigo Orso, Shayna Peterzell, Vanessa Thompson, Heather C Brenhous. Sex differences in prefrontal cortex microglia morphology: Impact of a two-hit model of adversity throughout development. Neuroscience letters. vol 738. 2021-05-17. PMID:32927000. |
ms led to fewer microglia in the infralimbic pfc of adolescent males. |
2021-05-17 |
2023-08-13 |
rat |
| Kelsea R Gildawie, Rodrigo Orso, Shayna Peterzell, Vanessa Thompson, Heather C Brenhous. Sex differences in prefrontal cortex microglia morphology: Impact of a two-hit model of adversity throughout development. Neuroscience letters. vol 738. 2021-05-17. PMID:32927000. |
taken together, these findings provide insight into how pfc microglia may differentially respond to challenges over development in males and females. |
2021-05-17 |
2023-08-13 |
rat |
| David Val-Laillet, Ameni Kanzari, Sylvie Guérin, Gwénaëlle Randuineau, Nicolas Coquer. A maternal Western diet during gestation and lactation modifies offspring's microglial cell density and morphology in the hippocampus and prefrontal cortex in Yucatan minipigs. Neuroscience letters. vol 739. 2021-04-30. PMID:32950568. |
a maternal western diet during gestation and lactation modifies offspring's microglial cell density and morphology in the hippocampus and prefrontal cortex in yucatan minipigs. |
2021-04-30 |
2023-08-13 |
Not clear |
| Lídia Cantacorps, Sandra Montagud-Romero, Olga Valverd. Curcumin treatment attenuates alcohol-induced alterations in a mouse model of foetal alcohol spectrum disorders. Progress in neuro-psychopharmacology & biological psychiatry. vol 100. 2021-04-28. PMID:32109509. |
we focused on inflammatory and epigenetic mechanisms by analysing the expression of pro-inflammatory mediators, such as il-6, tnf-α, and nf-κb, in the hippocampus and prefrontal cortex, as well as microglia and astrocyte activation in the dentate gyrus. |
2021-04-28 |
2023-08-13 |
mouse |
| Samuel C Woodburn, Justin L Bollinger, Eric S Wohle. Synaptic and behavioral effects of chronic stress are linked to dynamic and sex-specific changes in microglia function and astrocyte dystrophy. Neurobiology of stress. vol 14. 2021-03-23. PMID:33748354. |
in the present studies, male and female mice were exposed to 14 or 28 days of chronic unpredictable stress (cus) to assess molecular and cellular adaptations of microglia, astrocytes, and neurons in the medial pfc. |
2021-03-23 |
2023-08-13 |
mouse |
| Samuel C Woodburn, Justin L Bollinger, Eric S Wohle. Synaptic and behavioral effects of chronic stress are linked to dynamic and sex-specific changes in microglia function and astrocyte dystrophy. Neurobiology of stress. vol 14. 2021-03-23. PMID:33748354. |
fluorescence-activated cell sorting and gene expression analyses revealed that cus increased expression of select markers of phagocytosis in male pfc microglia. |
2021-03-23 |
2023-08-13 |
mouse |
| Brittany L Smith, Collin J Laaker, Kelsey R Lloyd, Adam R Hiltz, Teresa M Reye. Adolescent microglia play a role in executive function in male mice exposed to perinatal high fat diet. Brain, behavior, and immunity. vol 84. 2021-03-12. PMID:31765789. |
because the prefrontal cortex (pfc), which plays a key role in executive function, undergoes substantial postnatal adolescent pruning and microglia are actively involved in synaptic refinement, we hypothesized that microglia may play a role in mediating changes in brain development after maternal hf diet, with a specific focus on microglial activity during adolescence. |
2021-03-12 |
2023-08-13 |
mouse |
| Ru-Yue Wang, Yue Wang, Song Han, Yue Liu, Jun-Fa Li, Li Zha. [Changes in microglia number and Iba1 expression level in the prefrontal cortex of type 1 diabetic mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 73. issue 1. 2021-03-08. PMID:33665655. |
[changes in microglia number and iba1 expression level in the prefrontal cortex of type 1 diabetic mice]. |
2021-03-08 |
2023-08-13 |
mouse |
| Ru-Yue Wang, Yue Wang, Song Han, Yue Liu, Jun-Fa Li, Li Zha. [Changes in microglia number and Iba1 expression level in the prefrontal cortex of type 1 diabetic mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 73. issue 1. 2021-03-08. PMID:33665655. |
the aim of the present study was to observe the activation of microglia in the prefrontal cortex of type 1 diabetes mellitus (t1dm) mice, and the expression of the marker genes of the disease-associated microglia (dam) associated with neurodegenerative diseases. |
2021-03-08 |
2023-08-13 |
mouse |
| Ru-Yue Wang, Yue Wang, Song Han, Yue Liu, Jun-Fa Li, Li Zha. [Changes in microglia number and Iba1 expression level in the prefrontal cortex of type 1 diabetic mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 73. issue 1. 2021-03-08. PMID:33665655. |
the number and activation of microglia in the prefrontal cortex of mice were detected by immunofluorescence staining and western blot. |
2021-03-08 |
2023-08-13 |
mouse |
| Ru-Yue Wang, Yue Wang, Song Han, Yue Liu, Jun-Fa Li, Li Zha. [Changes in microglia number and Iba1 expression level in the prefrontal cortex of type 1 diabetic mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 73. issue 1. 2021-03-08. PMID:33665655. |
compared with con group, the iba1 protein expression and the number of microglia in prefrontal cortex of t1dm group increased significantly (p < 0.05). |
2021-03-08 |
2023-08-13 |
mouse |
| Ru-Yue Wang, Yue Wang, Song Han, Yue Liu, Jun-Fa Li, Li Zha. [Changes in microglia number and Iba1 expression level in the prefrontal cortex of type 1 diabetic mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 73. issue 1. 2021-03-08. PMID:33665655. |
these results suggest that the microglia are activated and transformed to dam type in the prefrontal cortex of t1dm mice. |
2021-03-08 |
2023-08-13 |
mouse |
| Lulin Ma, Juan Li, Junli Zhou, Dexin Zhang, Zhi Xiao, Tian Yu, Ying Li, Song Ca. Intravenous lidocaine alleviates postherpetic neuralgia in rats via regulation of neuroinflammation of microglia and astrocytes. iScience. vol 24. issue 2. 2021-02-20. PMID:33604528. |
microglia and astrocytes in spinal dorsal horn (sdh), prefrontal cortex (pfc), anterior cingulate cortex (acc), and hippocampus were analyzed. |
2021-02-20 |
2023-08-13 |
rat |
| Lulin Ma, Juan Li, Junli Zhou, Dexin Zhang, Zhi Xiao, Tian Yu, Ying Li, Song Ca. Intravenous lidocaine alleviates postherpetic neuralgia in rats via regulation of neuroinflammation of microglia and astrocytes. iScience. vol 24. issue 2. 2021-02-20. PMID:33604528. |
in addition, it reduced the activation of astrocyte but not microglia in pfc, acc, and hippocampus. |
2021-02-20 |
2023-08-13 |
rat |
| Lulin Ma, Juan Li, Junli Zhou, Dexin Zhang, Zhi Xiao, Tian Yu, Ying Li, Song Ca. Intravenous lidocaine alleviates postherpetic neuralgia in rats via regulation of neuroinflammation of microglia and astrocytes. iScience. vol 24. issue 2. 2021-02-20. PMID:33604528. |
intravenous lidocaine may relieve phn by inhibiting the activation of microglia and astrocyte in sdh or by reducing the neuroinflammation and astrocyte activation in pfc, acc, and hippocampus. |
2021-02-20 |
2023-08-13 |
rat |
| Helen Q Cai, Vibeke S Catts, Maree J Webster, Cherrie Galletly, Dennis Liu, Maryanne O'Donnell, Thomas W Weickert, Cynthia Shannon Weicker. Increased macrophages and changed brain endothelial cell gene expression in the frontal cortex of people with schizophrenia displaying inflammation. Molecular psychiatry. vol 25. issue 4. 2021-02-17. PMID:30214039. |
eight mrnas relating to bbb function, a microglia and three immune cell markers were measured by qpcr in the prefrontal cortex from 37 people with schizophrenia/schizoaffective disorder and 37 matched controls. |
2021-02-17 |
2023-08-13 |
Not clear |
| Xiao-Yan Li, Hong-Mei Wang, Ya Zhao, Chen Li, Jun Lu, Ji-Hong Wu, Ya T. [Effect of acupuncture on microglia activation in prefrontal cortex of chronic stress-induced depression rats]. Zhen ci yan jiu = Acupuncture research. vol 46. issue 1. 2021-02-10. PMID:33559426. |
[effect of acupuncture on microglia activation in prefrontal cortex of chronic stress-induced depression rats]. |
2021-02-10 |
2023-08-13 |
rat |
| Xiao-Yan Li, Hong-Mei Wang, Ya Zhao, Chen Li, Jun Lu, Ji-Hong Wu, Ya T. [Effect of acupuncture on microglia activation in prefrontal cortex of chronic stress-induced depression rats]. Zhen ci yan jiu = Acupuncture research. vol 46. issue 1. 2021-02-10. PMID:33559426. |
to observe the effect of acupuncture on the expression of proinflammatory cytokines interleukin-1β (il-1β), interleukin-6 (il-6), microglia marker ion calcium adaptor protein (iba-1) and triggering receptor expressed on myeloid cells 2 (trem2) in the prefrontal cortex of chronic stress-induced depression rats, so as to explore its antidepressant mechanism. |
2021-02-10 |
2023-08-13 |
rat |
| Yuchen Song, Haixia Yuan, Tianyi Chen, Manqi Lu, Shuang Lei, Xinmin Ha. An Shen Ding Zhi Ling Alleviates Symptoms of Attention Deficit Hyperactivity Disorder via Anti-Inflammatory Effects in Spontaneous Hypertensive Rats. Frontiers in pharmacology. vol 11. 2021-02-06. PMID:33536923. |
asdzl reduced the pro-inflammatory factors interleukin (il)-1β, il-4, il-6, tumor necrosis factor (tnf)-α and monocyte chemoattractant protein (mcp)-1 and increased anti-inflammatory factor il-10 in shrs, and decreased the activation of microglia, astrocytes and mast cells in the prefrontal cortex (pfc) and hippocampus. |
2021-02-06 |
2023-08-13 |
rat |