| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A N Verity, T L Wyatt, B Hajos, R M Eglen, P A Baecker, R M Johnso. Regulation of glial cell line-derived neurotrophic factor release from rat C6 glioblastoma cells. Journal of neurochemistry. vol 70. issue 2. 1998-02-24. PMID:9453547. |
we have monitored glial cell line-derived neurotrophic factor (gdnf) secretion from rat c6 glioblastoma cells by elisa. |
1998-02-24 |
2023-08-12 |
rat |
| L M Farkas, C Suter-Crazzolara, K Unsicke. GDNF induces the calretinin phenotype in cultures of embryonic striatal neurons. Journal of neuroscience research. vol 50. issue 3. 1998-02-19. PMID:9364321. |
glial cell line-derived neurotrophic factor (gdnf), a member of the transforming growth factor-beta (tgf-beta) superfamily, is a potent neurotrophic factor for several neuron populations in the central and peripheral nervous system. |
1998-02-19 |
2023-08-12 |
rat |
| K Luukko, P Suvanto, M Saarma, I Theslef. Expression of GDNF and its receptors in developing tooth is developmentally regulated and suggests multiple roles in innervation and organogenesis. Developmental dynamics : an official publication of the American Association of Anatomists. vol 210. issue 4. 1998-02-19. PMID:9415430. |
glial cell line-derived neurotrophic factor (gdnf) is a recently identified survival factor for several populations of neurons in the central and peripheral nervous system that also regulates kidney development. |
1998-02-19 |
2023-08-12 |
Not clear |
| H Sariola, K Saini. The tip-top branching ureter. Current opinion in cell biology. vol 9. issue 6. 1998-02-05. PMID:9425354. |
glial cell line derived neurotrophic factor (gdnf) has recently been shown to regulate ureteric branching morphogenesis and is thereby the first defined signalling molecule in the embryonic metanephric kidney. |
1998-02-05 |
2023-08-12 |
Not clear |
| N Matsushita, Y Fujita, M Tanaka, T Nagatsu, K Kiuch. Cloning and structural organization of the gene encoding the mouse glial cell line-derived neurotrophic factor, GDNF. Gene. vol 203. issue 2. 1998-01-26. PMID:9426245. |
cloning and structural organization of the gene encoding the mouse glial cell line-derived neurotrophic factor, gdnf. |
1998-01-26 |
2023-08-12 |
mouse |
| N Matsushita, Y Fujita, M Tanaka, T Nagatsu, K Kiuch. Cloning and structural organization of the gene encoding the mouse glial cell line-derived neurotrophic factor, GDNF. Gene. vol 203. issue 2. 1998-01-26. PMID:9426245. |
cdna for glial cell line-derived neurotrophic factor (gdnf) was cloned from mouse neonatal brain by the method of 5'-rapid amplification of cdna end (5'-race), and the sequence of it's 5'-untranslated region (5'-utr) was determined. |
1998-01-26 |
2023-08-12 |
mouse |
| S Jing, Y Yu, M Fang, Z Hu, P L Holst, T Boone, J Delaney, H Schultz, R Zhou, G M Fo. GFRalpha-2 and GFRalpha-3 are two new receptors for ligands of the GDNF family. The Journal of biological chemistry. vol 272. issue 52. 1998-01-23. PMID:9407096. |
the receptor for glial cell line-derived neurotrophic factor (gdnf) consists of gfralpha-1 and ret. |
1998-01-23 |
2023-08-12 |
Not clear |
| C Bidaud, R Salomon, G Van Camp, A Pelet, T Attié, C Eng, M Bonduelle, J Amiel, C Nihoul-Fékété, P J Willems, A Munnich, S Lyonne. Endothelin-3 gene mutations in isolated and syndromic Hirschsprung disease. European journal of human genetics : EJHG. vol 5. issue 4. 1998-01-21. PMID:9359047. |
four susceptibility genes have recently been identified in hscr, namely the ret proto-oncogene, the glial cell line-derived neurotrophic factor (gdnf), the endothelin b receptor (ednrb) and the endothelin-3 genes (edn3). |
1998-01-21 |
2023-08-12 |
Not clear |
| X Lu, T Hag. Glial cell line-derived neurotrophic factor prevents death, but not reductions in tyrosine hydroxylase, of injured nigrostriatal neurons in adult rats. The Journal of comparative neurology. vol 388. issue 3. 1998-01-14. PMID:9368855. |
glial cell line-derived neurotrophic factor (gdnf) promotes survival of mesencephalic dopaminergic neurons in vitro and when injected locally into the brains of lesioned adult animals. |
1998-01-14 |
2023-08-12 |
rat |
| A Ho, M Blu. Regulation of astroglial-derived dopaminergic neurotrophic factors by interleukin-1 beta in the striatum of young and middle-aged mice. Experimental neurology. vol 148. issue 1. 1998-01-07. PMID:9398477. |
in order to determine whether il-1 beta effects on dopaminergic axonal sprouting are mediated by the induction of astroglial-derived dopaminergic neurotrophic factors, effects of il-1 beta treatment on acidic and basic fibroblast growth factor (afgf and bfgf) and glial cell line-derived growth factor (gdnf) gene expression were examined in primary striatal astrocyte cultures and after in vivo administration. |
1998-01-07 |
2023-08-12 |
mouse |
| A Björklund, C Rosenblad, C Winkler, D Kiri. Studies on neuroprotective and regenerative effects of GDNF in a partial lesion model of Parkinson's disease. Neurobiology of disease. vol 4. issue 3-4. 1997-12-10. PMID:9361295. |
in the in vivo experiments performed in this model glial cell line-derived neurotrophic factor (gdnf) has been shown to exert neurotrophic effects both at the level of the cell bodies in the substantia nigra and at the level of the axon terminals in the striatum. |
1997-12-10 |
2023-08-12 |
rat |
| G T Liberatore, J Y Wong, M J Porritt, G A Donnan, D W Howell. Expression of glial cell line-derived neurotrophic factor (GDNF) mRNA following mechanical injury to mouse striatum. Neuroreport. vol 8. issue 14. 1997-11-26. PMID:9331921. |
expression of glial cell line-derived neurotrophic factor (gdnf) mrna following mechanical injury to mouse striatum. |
1997-11-26 |
2023-08-12 |
mouse |
| G T Liberatore, J Y Wong, M J Porritt, G A Donnan, D W Howell. Expression of glial cell line-derived neurotrophic factor (GDNF) mRNA following mechanical injury to mouse striatum. Neuroreport. vol 8. issue 14. 1997-11-26. PMID:9331921. |
although glial cell line-derived neurotrophic factor (gdnf) expression is low in the adult brain, its administration protects dopaminergic neurons against a range of insults, leading to the suggestion of a role in dopaminergic regeneration. |
1997-11-26 |
2023-08-12 |
mouse |
| D C Molliver, D E Wright, M L Leitner, A S Parsadanian, K Doster, D Wen, Q Yan, W D Snide. IB4-binding DRG neurons switch from NGF to GDNF dependence in early postnatal life. Neuron. vol 19. issue 4. 1997-11-21. PMID:9354331. |
we have tested the role of glial cell line-derived neurotrophic factor (gdnf) in regulating a group of putatively nociceptive dorsal root ganglion (drg) neurons that do not express calcitonin gene-related peptide (cgrp) and that downregulate the nerve growth factor (ngf) receptor tyrosine kinase, trka, after birth. |
1997-11-21 |
2023-08-12 |
Not clear |
| J Widenfalk, C Nosrat, A Tomac, H Westphal, B Hoffer, L Olso. Neurturin and glial cell line-derived neurotrophic factor receptor-beta (GDNFR-beta), novel proteins related to GDNF and GDNFR-alpha with specific cellular patterns of expression suggesting roles in the developing and adult nervous system and in peripheral organs. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 21. 1997-11-20. PMID:9334423. |
neurturin and glial cell line-derived neurotrophic factor receptor-beta (gdnfr-beta), novel proteins related to gdnf and gdnfr-alpha with specific cellular patterns of expression suggesting roles in the developing and adult nervous system and in peripheral organs. |
1997-11-20 |
2023-08-12 |
mouse |
| R O Heuckeroth, P Kotzbauer, N G Copeland, D J Gilbert, N A Jenkins, D B Zimonjic, N C Popescu, E M Johnson, J Milbrand. Neurturin, a novel neurotrophic factor, is localized to mouse chromosome 17 and human chromosome 19p13.3. Genomics. vol 44. issue 1. 1997-11-18. PMID:9286710. |
neurturin is a potent neurotrophic factor closely related to glial cell line-derived neurotrophic factor (gdnf, 40% amino acid sequence identity) and, like gdnf, can promote the survival of numerous neuronal populations including sympathetic, nodose, and dorsal root ganglion sensory neurons. |
1997-11-18 |
2023-08-12 |
mouse |
| P Suvanto, K Wartiovaara, M Lindahl, U Arumae, M Moshnyakov, N Horelli-Kuitunen, M S Airaksinen, A Palotie, H Sariola, M Saarm. Cloning, mRNA distribution and chromosomal localisation of the gene for glial cell line-derived neurotrophic factor receptor beta, a homologue to GDNFR-alpha. Human molecular genetics. vol 6. issue 8. 1997-10-30. PMID:9259272. |
glial cell line-derived neurotrophic factor (gdnf) is a potent survival factor for central dopaminergic neurons, motor neurons and several other populations of neurons in the central and peripheral nervous system. |
1997-10-30 |
2023-08-12 |
mouse |
| K Abe, T Hayashi, Y Itoyam. Amelioration of brain edema by topical application of glial cell line-derived neurotrophic factor in reperfused rat brain. Neuroscience letters. vol 231. issue 1. 1997-10-23. PMID:9280162. |
glial cell line-derived neurotrophic factor (gdnf) was applied topically on the brain surface of reperfused rat brain after 90 min of transient middle cerebral artery occlusion. |
1997-10-23 |
2023-08-12 |
rat |
| A C Granholm, J L Mott, K Bowenkamp, S Eken, S Henry, B J Hoffer, P A Lapchak, M R Palmer, C van Horne, G A Gerhard. Glial cell line-derived neurotrophic factor improves survival of ventral mesencephalic grafts to the 6-hydroxydopamine lesioned striatum. Experimental brain research. vol 116. issue 1. 1997-10-23. PMID:9305812. |
in an attempt to expand the developmental window useful for grafting of mesencephalic tissue and increase the fiber outgrowth from grafted dopaminergic neurons, we have pretreated fetal mesencephalic tissue with the dopaminotrophic factor glial cell line-derived neurotrophic factor (gdnf). |
1997-10-23 |
2023-08-12 |
rat |
| Z Zhang, Y Miyoshi, P A Lapchak, F Collins, D Hilt, C Lebel, R Kryscio, D M Gas. Dose response to intraventricular glial cell line-derived neurotrophic factor administration in parkinsonian monkeys. The Journal of pharmacology and experimental therapeutics. vol 282. issue 3. 1997-10-17. PMID:9316852. |
a double-blinded study was conducted to evaluate the dose response of hemiparkinsonian rhesus monkeys to intracerebroventricular (icv) injections of recombinant methionine human glial cell line-derived neurotrophic factor (gdnf). |
1997-10-17 |
2023-08-12 |
human |