| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hui Li, Qi-Qin Dan, Yan-Jun Chen, Li Chen, Hong-Tian Zhang, De-Zhi Mu, Ting-Hua Wan. Cellular Localization and Distribution of TGF-β1, GDNF and PDGF-BB in the Adult Primate Central Nervous System. Neurochemical research. 2023-03-28. PMID:36976393. |
the available data on the localization of transforming growth factor beta1 (tgf-β1), glial cell line-derived neurotrophic factor (gdnf), and platelet-derived growth factor-bb (pdgf-bb) in the adult primate and human central nervous system (cns) are limited and lack comprehensive and systematic information. |
2023-03-28 |
2023-08-14 |
human |
| Meaghan E McCoy, Anna K Kamitakahar. Ontogeny and Trophic Factor Sensitivity of Gastrointestinal Projecting Vagal Sensory Cell Types. eNeuro. 2023-03-27. PMID:36973009. |
experiments to screen for trophic factor sensitivity revealed that brain derived neurotrophic factor (bdnf) and glial cell derived neurotrophic factor (gdnf) robustly stimulate neurite outgrowth from vsns |
2023-03-27 |
2023-08-14 |
mouse |
| Shi-Xin Wu, Guo-Wen Wang, You-Gui Fang, Yong-Wei Chen, Yan-Ying Jin, Xue-Tong Liu, Gong-Xue Jia, Qi-En Yan. Transcriptome analysis reveals dysregulated gene expression networks in Sertoli cells of cattle-yak hybrids. Theriogenology. vol 203. 2023-03-26. PMID:36966583. |
notably, niche factor glial cell derived neurotrophic factor (gdnf) was upregulated, and genes involved in retinoic acid (ra) biogenesis were changed in sertoli cells of cattle-yak, suggesting possible impairments of spermatogonial fate decisions. |
2023-03-26 |
2023-08-14 |
cattle |
| Kärt Mätlik, Soophie Olfat, Mark Cary Cowlishaw, Eva Domenech Moreno, Saara Ollila, Jaan-Olle Andresso. Heliyon. vol 9. issue 3. 2023-03-16. PMID:36923835. |
we previously showed that the replacement of the negative regulatory elements from the 3'utr of glial cell line-derived neurotrophic factor (gdnf) resulted in increased endogenous gdnf expression while retaining its normal spatiotemporal expression pattern. |
2023-03-16 |
2023-08-14 |
Not clear |
| Vilasagaram Srinivas, Saikanth Varma, Suryam Reddy Kona, Ahamed Ibrahim, Asim K Duttaroy, Sanjay Basa. Dietary omega-3 fatty acid deficiency from pre-pregnancy to lactation affects expression of genes involved in hippocampal neurogenesis of the offspring. Prostaglandins, leukotrienes, and essential fatty acids. vol 191. 2023-03-16. PMID:36924605. |
among the genes involved in neurogenesis, the expression of brain-specific tenascin-r (tnr) was downregulated to a greater extent (∼31 fold), followed by adenosine a2a receptor (a2aar), dopamine receptor d2 (drd2), glial cell line-derived neurotrophic factor (gdnf) expression in the n-3 pufa deficient hippocampus. |
2023-03-16 |
2023-08-14 |
mouse |
| Shu-Yan Tong, Rui-Wen Wang, Qian Li, Yi Liu, Xiao-Yan Yao, De-Qin Geng, Dian-Shuai Gao, Chao Re. Serum glial cell line-derived neurotrophic factor (GDNF) a potential biomarker of executive function in Parkinson's disease. Frontiers in neuroscience. vol 17. 2023-03-13. PMID:36908789. |
serum glial cell line-derived neurotrophic factor (gdnf) a potential biomarker of executive function in parkinson's disease. |
2023-03-13 |
2023-08-14 |
Not clear |
| Shu-Yan Tong, Rui-Wen Wang, Qian Li, Yi Liu, Xiao-Yan Yao, De-Qin Geng, Dian-Shuai Gao, Chao Re. Serum glial cell line-derived neurotrophic factor (GDNF) a potential biomarker of executive function in Parkinson's disease. Frontiers in neuroscience. vol 17. 2023-03-13. PMID:36908789. |
glial cell line-derived neurotrophic factor (gdnf), as the strongest protective neurotrophic factor for dopaminergic neurons (dans), may play a role in ef to some extent. |
2023-03-13 |
2023-08-14 |
Not clear |
| Ella A Kasanga, Yoonhee Han, Walter Navarrete, Robert McManus, Marla K Shifflet, Caleb Parry, Arturo Barahona, Fredric P Manfredsson, Vicki A Nejtek, Jason R Richardson, Michael F Salvator. Differential expression of RET and GDNF family receptor, GFR-α1, between striatum and substantia nigra following nigrostriatal lesion: a case for diminished GDNF-signaling. bioRxiv : the preprint server for biology. 2023-03-13. PMID:36909534. |
although glial cell line-derived neurotrophic factor (gdnf) showed efficacy in preclinical and early clinical studies to alleviate parkinsonian signs in parkinson's disease (pd), later trials did not meet primary endpoints, giving pause to consider further investigation. |
2023-03-13 |
2023-08-14 |
rat |
| Darya Bazovkina, Nina B Illarionova, Elizabeth A Kulikova, Ekaterina Yu Bazhenova, Nadezhda A Sinyakova, Nikita V Khotskin, Sergey Nikitin, Vasily S Lankin, Elena E Terenina, Oleg V Trapezov, Aleksandr V Kuliko. Studying the brain monoaminergic systems and neurotrophic factors in minipigs with high and low tolerance to the presence of human. Brain, behavior and evolution. 2023-03-13. PMID:36913918. |
also, a decrease in the expression of genes encoding bdnf (brain-derived neurotrophic factor) and gdnf (glial cell line-derived neurotrophic factor) was revealed in lt minipigs. |
2023-03-13 |
2023-08-14 |
human |
| Yaping Mao, Dan Li, Qiaoqiao Yang, Xiucong Pei, Zhiwen Duan, Mingyue M. Prenatal BPA exposure disrupts male reproductive functions by interfering with DNA methylation and GDNF expression in the testes of male offspring rats. Environmental science and pollution research international. 2023-03-02. PMID:36864339. |
glial cell line-derived neurotrophic factor (gdnf) plays an important role in maintaining normal spermatogenesis and fertility. |
2023-03-02 |
2023-08-14 |
rat |
| Laura Stahn, Justyna Rasińska, Tilo Dehne, Stefanie Schreyer, Aileen Hakus, Manfred Gossen, Barbara Steiner, Shabnam Hemmati-Sadegh. Sleeping Beauty transposon system for GDNF overexpression of entrapped stem cells in fibrin hydrogel in a rat model of Parkinson's disease. Drug delivery and translational research. 2023-02-28. PMID:36853436. |
however, the use of glial cell line-derived neurotrophic factor (gdnf) to provide regenerative effects for neurons is promising. |
2023-02-28 |
2023-08-14 |
rat |
| Xiaoyan Wang, Yuehan Wang, Xuelian Chen, Tinglei Li, Shu Zhang, Rong Dong, Zhe Che. The central glial cell line-derived neurotrophic factor (GDNF) regulates pulmonary function in asthmatic rats. Annals of translational medicine. vol 11. issue 2. 2023-02-23. PMID:36819542. |
the central glial cell line-derived neurotrophic factor (gdnf) regulates pulmonary function in asthmatic rats. |
2023-02-23 |
2023-08-14 |
rat |
| Xiaoyan Wang, Yuehan Wang, Xuelian Chen, Tinglei Li, Shu Zhang, Rong Dong, Zhe Che. The central glial cell line-derived neurotrophic factor (GDNF) regulates pulmonary function in asthmatic rats. Annals of translational medicine. vol 11. issue 2. 2023-02-23. PMID:36819542. |
this study aimed to investigate the effect of glial cell line-derived neurotrophic factor (gdnf) on asthma attacks. |
2023-02-23 |
2023-08-14 |
rat |
| Yifan Wu, Lingtao Kong, Anqi Yang, Kaiqi Xin, Yihui Lu, Xintong Yan, Wen Liu, Yue Zhu, Yingrui Guo, Xiaowei Jiang, Yifang Zhou, Qikun Sun, Yanqing Tang, Feng W. Gray matter volume reduction in orbitofrontal cortex correlated with plasma glial cell line-derived neurotrophic factor (GDNF) levels within major depressive disorder. NeuroImage. Clinical. vol 37. 2023-02-05. PMID:36739789. |
gray matter volume reduction in orbitofrontal cortex correlated with plasma glial cell line-derived neurotrophic factor (gdnf) levels within major depressive disorder. |
2023-02-05 |
2023-08-14 |
Not clear |
| Yifan Wu, Lingtao Kong, Anqi Yang, Kaiqi Xin, Yihui Lu, Xintong Yan, Wen Liu, Yue Zhu, Yingrui Guo, Xiaowei Jiang, Yifang Zhou, Qikun Sun, Yanqing Tang, Feng W. Gray matter volume reduction in orbitofrontal cortex correlated with plasma glial cell line-derived neurotrophic factor (GDNF) levels within major depressive disorder. NeuroImage. Clinical. vol 37. 2023-02-05. PMID:36739789. |
in particular, plasma glial cell line-derived neurotrophic factor (gdnf) has been suggested as a potential biomarker that may be associated with disease activity and neurological progression in mdd. |
2023-02-05 |
2023-08-14 |
Not clear |
| Praseeda Mol, Rex Devasahayam Arokia Balaya, Shobha Dagamajalu, Sreeranjini Babu, Pavithra Chandrasekaran, Reshma Raghavan, Sneha Suresh, Namitha Ravishankara, Anu Hemalatha Raju, Bipin Nair, Prashant Kumar Modi, Anita Mahadevan, Thottethodi Subrahmanya Keshava Prasad, Rajesh Raj. A network map of GDNF/RET signaling pathway in physiological and pathological conditions. Journal of cell communication and signaling. 2023-01-30. PMID:36715855. |
glial cell line-derived neurotrophic factor (gdnf) signals through a multi-component receptor system predominantly consisting of glycosyl-phosphatidylinositol-anchored gdnf family receptor alpha-1 (gfrα1) and the rearranged during transfection (ret) receptor tyrosine kinase. |
2023-01-30 |
2023-08-14 |
Not clear |
| Soophie Olfat, Kärt Mätlik, Jaakko J Kopra, Daniel R Garton, Vilma H Iivanainen, Dipabarna Bhattacharya, Johan Jakobsson, T Petteri Piepponen, Jaan-Olle Andresso. Increased physiological GDNF levels have no effect on dopamine neuron protection and restoration in a proteasome inhibition mouse model of Parkinson's disease. eNeuro. 2023-01-23. PMID:36690469. |
glial cell line-derived neurotrophic factor (gdnf) promotes the survival of dopamine neurons |
2023-01-23 |
2023-08-14 |
mouse |
| Nina Truter, Leoné Malan, M Faadiel Esso. Glial cell activity in cardiovascular diseases and risk of acute myocardial infarction. American journal of physiology. Heart and circulatory physiology. 2023-01-20. PMID:36662577. |
this includes discussions on the potential role for contributing factors in ami risk, i.e., autonomic nervous system dysfunction, glial-neurotrophic and ischemic risk markers (glial cell line-derived neurotrophic factor [gdnf], astrocytic s100 calcium-binding protein b [s100b], silent myocardial ischemia, and cardiac troponin t [ctnt]). |
2023-01-20 |
2023-08-14 |
Not clear |
| Li-Kang Zhang, Jia-Hui Sun, Sheng Liu, Wen-Liang Zhang, Jian-Long Zo. 3D culture of the spinal cord with roots as an ex vivo model for comparative studies of motor and sensory nerve regeneration. Experimental neurology. 2023-01-18. PMID:36652972. |
next, we detected asymmetric ventral and dorsal root regeneration in response to nerve growth factor (ngf) and glial cell line-derived neurotrophic factor (gdnf), and we observed motor and sensory schwann cell phenotypes in the regenerated ventral and dorsal roots, respectively. |
2023-01-18 |
2023-08-14 |
Not clear |
| Muhammad S Aldhshan, Tooru M Mizun. Environmental enrichment accentuates glucose-induced feeding suppression and glial cell line-derived neurotrophic factor gene expression in the hypothalamus of mice. Nutritional neuroscience. 2023-01-12. PMID:36634108. |
brain-derived neurotrophic factor (bdnf) and glial cell line-derived neurotrophic factor (gdnf) are expressed in the hypothalamus and their expression is stimulated by glucose. |
2023-01-12 |
2023-08-14 |
mouse |