| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Simon Musyoka Mwangi, Ge Li, Arun Balasubramaniam, Didier Merlin, Paul A Dawson, Young C Jang, C Michael Hart, Mark J Czaja, Shanthi Srinivasa. Glial cell derived neurotrophic factor prevents western diet and palmitate-induced hepatocyte oxidative damage and death through SIRT3. Scientific reports. vol 12. issue 1. 2022-09-23. PMID:36151131. |
in this study we investigated the mechanisms involved in the induction of oxidative stress and impairment of mitochondrial quality control and mitophagy in hepatocytes by the saturated fatty acid palmitate and western diet feeding in mice and if their harmful effects could be reversed by the neurotrophic factor glial cell derived neurotrophic factor (gdnf). |
2022-09-23 |
2023-08-14 |
mouse |
| Mikhail S Zinchuk, Alla B Guekht, Tatiana A Druzhkova, Natalia V Gulyaeva, Alexander A Shpa. Glial cell line-derived neurotrophic factor (GDNF) in blood serum and lacrimal fluid of patients with a current depressive episode. Journal of affective disorders. 2022-09-18. PMID:36116600. |
glial cell line-derived neurotrophic factor (gdnf) in blood serum and lacrimal fluid of patients with a current depressive episode. |
2022-09-18 |
2023-08-14 |
Not clear |
| Robert H Baloh, J Patrick Johnson, Pablo Avalos, Peggy Allred, Soshana Svendsen, Genevieve Gowing, Kristina Roxas, Amanda Wu, Becky Donahue, Sheryl Osborne, George Lawless, Brandon Shelley, Koral Wheeler, Carolyn Prina, Dana Fine, Tami Kendra-Romito, Haniah Stokes, Vicki Manoukian, Abirami Muthukumaran, Leslie Garcia, Maria G Bañuelos, Marlesa Godoy, Catherine Bresee, Hong Yu, Doniel Drazin, Lindsey Ross, Robert Naruse, Harish Babu, Eric A Macklin, Ashley Vo, Ashraf Elsayegh, Warren Tourtellotte, Marcel Maya, Matthew Burford, Frank Diaz, Chirag G Patil, Richard A Lewis, Clive N Svendse. Transplantation of human neural progenitor cells secreting GDNF into the spinal cord of patients with ALS: a phase 1/2a trial. Nature medicine. 2022-09-05. PMID:36064599. |
dysfunctional astrocytes may contribute to disease and glial cell line-derived neurotrophic factor (gdnf) can be protective. |
2022-09-05 |
2023-08-14 |
human |
| Xu-Ping Jiang, Yao-Xiang Sun, Bin Qiao, Wen-Jiao Zhu, Yu-Jiao Chu, Miao-Miao Sun, Rui-Jie Tang, Tie-Liang Ma, Zhi-An Tan. Youjing granules ameliorate spermatogenesis in rats through regulating the prolifereation of spermatogonial stem cells. Chinese journal of natural medicines. vol 20. issue 8. 2022-08-28. PMID:36031230. |
results indicated that yg increased the expression of self-renewal and proliferation-related molecules such as glial cell line derived neurotrophic factor (gdnf) and fibroblast growth factor-2 (fgf2), and improved the quality of sperm and the proliferation of sscs. |
2022-08-28 |
2023-08-14 |
mouse |
| Xianping He, Jingyao Song, He Gao, Zhenyang Li, Xiaochun Wang, Qiaoling Zeng, Yucen Xiao, Jiaxin Feng, Dongdong Zhou, Gaomao Wan. Serum brain-derived neurotrophic factor and glial cell-derived neurotrophic factor in patients with first-episode depression at different ages. International journal of psychiatry in clinical practice. 2022-08-18. PMID:35980319. |
we investigated the differences in serum brain-derived neurotrophic factor (bdnf) and glial cell line-derived neurotrophic factor (gdnf) levels and clinical symptoms with first-episode depression at different ages. |
2022-08-18 |
2023-08-14 |
Not clear |
| Zi-Rong Li, De-Guo Liu, Sheng Xie, Yu-Hong Wang, Yuan-Shan Han, Chun-Yan Li, Man-Shu Zou, Hai-Xing Jian. Sleep deprivation leads to further impairment of hippocampal synaptic plasticity by suppressing melatonin secretion in the pineal gland of chronically unpredictable stress rats. European journal of pharmacology. 2022-07-25. PMID:35878808. |
expression of ionic calcium-binding adaptor 1 (iba-1), downregulates the secretion of several synaptic plasticity-related proteins, notably camp response element binding protein (creb), glial cell line-derived neurotrophic factor (gdnf), and the synaptic scaffolding protein spinophiline (spinophiline). |
2022-07-25 |
2023-08-14 |
rat |
| Guangyue Yang, Liping Zhuang, Tiantian Sun, Yee Hui Yeo, Le Tao, Wei Zhang, Wenting Ma, Liu Wu, Zongguo Yang, Yanqin Yang, Dongying Xue, Jie Zhang, Rilu Feng, Ebert Matthias P, Steven Dooley, Ekihiro Seki, Ping Liu, Cheng Li. Serum Glial Cell Line-Derived Neurotrophic Factor (sGDNF) Is a Novel Biomarker in Predicting Cirrhosis in Patients with Chronic Hepatitis B. Canadian journal of gastroenterology & hepatology. vol 2022. 2022-07-20. PMID:35855954. |
we assessed the potential of glial cell line-derived neurotrophic factor (gdnf) as a useful biomarker to predict cirrhosis in chronic hepatitis b (chb) patients. |
2022-07-20 |
2023-08-14 |
Not clear |
| Mohaddeseh Rahbaran, Angelina Olegovna Zekiy, Mahta Bahramali, Mohammadsaleh Jahangir, Mahsa Mardasi, Delaram Sakhaei, Lakshmi Thangavelu, Navid Shomali, Majid Zamani, Ali Mohammadi, Negin Rahnam. Therapeutic utility of mesenchymal stromal cell (MSC)-based approaches in chronic neurodegeneration: a glimpse into underlying mechanisms, current status, and prospects. Cellular & molecular biology letters. vol 27. issue 1. 2022-07-16. PMID:35842587. |
the msc-mediated desired effect is mainly a result of secretion of immunomodulatory factors in association with release of various neurotrophic factors (ntfs), such as glial cell line-derived neurotrophic factor (gdnf) and brain-derived neurotrophic factor (bdnf). |
2022-07-16 |
2023-08-14 |
Not clear |
| Muhammad S Aldhshan, Gursagar Jhanji, Nicole J Poritsanos, Tooru M Mizun. Glucose Stimulates Glial Cell Line-Derived Neurotrophic Factor Gene Expression in Microglia through a GLUT5-Independent Mechanism. International journal of molecular sciences. vol 23. issue 13. 2022-07-09. PMID:35806073. |
however, nutritional regulation of anorexigenic glial cell line-derived neurotrophic factor (gdnf) and orexigenic mesencephalic astrocyte-derived neurotrophic factor (manf) expression in specific cell types remains poorly understood. |
2022-07-09 |
2023-08-14 |
Not clear |
| Yan-Hua Yang, Wei Qian, Xiao-Hua Hou, Chi-Bing Da. Bifidobacterium bifidum and Bacteroides fragilis Induced Differential Immune Regulation of Enteric Glial Cells Subjected to Exogenous Inflammatory Stimulation. Inflammation. 2022-07-01. PMID:35776290. |
after pretreatment with lipopolysaccharide (lps) and interferon-γ (ifn-γ), the expressions of major histocompatibility complex class ii (mhc-ii), cd80, cd86, glial cell line-derived neurotrophic factor (gdnf), toll-like receptor 2 (tlr-2), and tumor necrosis factor-α (tnf-α) in egcs were detected using polymerase chain reaction and western blot after co-culture with the supernatants of b.b. |
2022-07-01 |
2023-08-14 |
Not clear |
| Sergei G Kalinichenko, Anatoliy V Korobtsov, Natalya Yu Matveeva, Igor I Pushchi. Topography of neurotrophins in the rat neocortex and their role in neuron apoptosis after experimental ischemic stroke. Journal of chemical neuroanatomy. 2022-06-19. PMID:35718293. |
we examined the immunolocalization of brain-derived neurotrophic factor (bdnf), neurotrophin-3, and glial cell line-derived neurotrophic factor (gdnf) in the parietal cortex using a rat model of ischemic stroke due to permanent occlusion of the middle cerebral artery. |
2022-06-19 |
2023-08-14 |
rat |
| Alexander A Shpak, Alla B Guekht, Tatiana A Druzhkova, Anna A Troshina, Natalia V Gulyaev. Glial cell line-derived neurotrophic factor (GDNF) in patients with primary open-angle glaucoma and age-related cataract. Molecular vision. vol 28. 2022-06-03. PMID:35656168. |
glial cell line-derived neurotrophic factor (gdnf) in patients with primary open-angle glaucoma and age-related cataract. |
2022-06-03 |
2023-08-14 |
Not clear |
| Alexander A Shpak, Alla B Guekht, Tatiana A Druzhkova, Anna A Troshina, Natalia V Gulyaev. Glial cell line-derived neurotrophic factor (GDNF) in patients with primary open-angle glaucoma and age-related cataract. Molecular vision. vol 28. 2022-06-03. PMID:35656168. |
to study glial cell line-derived neurotrophic factor (gdnf) concentrations in aqueous humor (ah), lacrimal fluid (lf), and blood serum (bs) in patients with age-related cataract and primary open-angle glaucoma (poag). |
2022-06-03 |
2023-08-14 |
Not clear |
| Roberto Bonanni, Ida Cariati, Umberto Tarantino, Giovanna D'Arcangelo, Virginia Tancred. Physical Exercise and Health: A Focus on Its Protective Role in Neurodegenerative Diseases. Journal of functional morphology and kinesiology. vol 7. issue 2. 2022-06-01. PMID:35645300. |
in this regard, neurotrophins, such as brain-derived neurotrophic factor (bdnf), nerve growth factor (ngf), glia cell line-derived neurotrophic factor (gdnf), neurotrophin-3 (nt-3), and neurotrophin-4 (nt-4), have been suggested as key mediators of brain health benefits, as they are involved in neurogenesis, neuronal survival, and synaptic plasticity. |
2022-06-01 |
2023-08-13 |
Not clear |
| Mayur S Parmar, Erika Allen, Shreya Narain, Deepesh Khanna, Jane Cavanaug. DNSP-11 reduces 6-OHDA-induced caspase 3/7 activation in an SH-SY5Y cell model: Potential Role of ERK signaling pathway? FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35555764. |
glial cell line-derived neurotrophic factor (gdnf) has been shown to be a promising therapeutic molecule for treating parkinson's disease (pd). |
2022-05-13 |
2023-08-13 |
human |
| Andres Samos, Vanessa McGaughey, Sandra Rieger, Thomas S Liss. Reawakening GDNF's regenerative past in mice and humans. Regenerative therapy. vol 20. 2022-05-05. PMID:35509264. |
according to phylogenic analysis, the glial cell line-derived neurotrophic factor (gdnf) signaling pathway, but not other family members, is conserved in axolotls, a salamander with remarkable regenerative capacity. |
2022-05-05 |
2023-08-13 |
mouse |
| Lucas B Doretto, Arno J Butzge, Rafael T Nakajima, Emanuel R M Martinez, Beatriz Marques de Souza, Maira da Silva Rodrigues, Ivana F Rosa, Juliana M B Ricci, Aldo Tovo-Neto, Daniel F Costa, Guilherme Malafaia, Changwei Shao, Rafael H Nóbreg. Gdnf Acts as a Germ Cell-Derived Growth Factor and Regulates the Zebrafish Germ Stem Cell Niche in Autocrine- and Paracrine-Dependent Manners. Cells. vol 11. issue 8. 2022-04-23. PMID:35455974. |
glial cell line-derived neurotrophic factor (gdnf) and its receptor (gdnf family receptor α1-gfrα1) are well known to mediate spermatogonial stem cell (ssc) proliferation and survival in mammalian testes. |
2022-04-23 |
2023-08-13 |
zebrafish |
| Alessandro Stefani, Mariangela Pierantozzi, Silvia Cardarelli, Lucrezia Stefani, Rocco Cerroni, Matteo Conti, Elena Garasto, Nicola B Mercuri, Carmine Marini, Patrizia Sucapan. Neurotrophins as Therapeutic Agents for Parkinson's Disease; New Chances From Focused Ultrasound? Frontiers in neuroscience. vol 16. 2022-04-11. PMID:35401084. |
in a rodent model for huntington's disease, engineered liposomes can carry glial cell line-derived neurotrophic factor (gdnf) plasmid dna (gdnfp) to form a gdnfp-liposome (gdnfp-lps) complex through pulsed fus exposures with microbubbles; in a subacute mptp-pd model, the combination of intravenous administration of neurotrophic factors (either through protein or gene delivery) plus fus did curb nigrostriatal degeneration. |
2022-04-11 |
2023-08-13 |
Not clear |
| Xuling Liu, Guangyue Yang, Tiantian Sun, Le Tao, Dongxiao Shen, Wei Zhang, Jie Zhang, Dongying Xue, Bei Chen, Liu Wu, Cheng Liu, Wenting M. Glial cell line-derived neurotrophic factor contributes to alcoholic-induced liver injury by regulating the NF-κB pathway. Alcoholism, clinical and experimental research. 2022-03-26. PMID:35338490. |
accumulating evidence suggests an important role of glial cell line-derived neurotrophic factor (gdnf) in several diseases. |
2022-03-26 |
2023-08-13 |
Not clear |
| Masahide Takahash. RET receptor signaling: Function in development, metabolic disease, and cancer. Proceedings of the Japan Academy. Series B, Physical and biological sciences. vol 98. issue 3. 2022-03-14. PMID:35283407. |
ret receptors are physiologically activated by glial cell line-derived neurotrophic factor (gdnf) family ligands that bind to the coreceptor gdnf family receptor α (gfrα). |
2022-03-14 |
2023-08-13 |
human |