| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhe Zhang, Grace Y Sun, Shinghua Din. Glial Cell Line-Derived Neurotrophic Factor and Focal Ischemic Stroke. Neurochemical research. vol 46. issue 10. 2021-09-16. PMID:33591443. |
glial cell line-derived neurotrophic factor (gdnf) was originally isolated from a rat glioma cell-line and regarded as a potent survival neurotrophic factor. |
2021-09-16 |
2023-08-13 |
human |
| Serena Stanga, Marina Boido, Pascal Kienlen-Campar. How to Build and to Protect the Neuromuscular Junction: The Role of the Glial Cell Line-Derived Neurotrophic Factor. International journal of molecular sciences. vol 22. issue 1. 2021-09-13. PMID:33374485. |
we focus here on the contribution of the glial cell line-derived neurotrophic factor (gdnf) to these processes and to its potential role in the protection of the nmj during neurodegeneration. |
2021-09-13 |
2023-08-13 |
Not clear |
| Chaoyu Liu, Xiaohua Li, Qilong Zhao, Yuancai Xie, Xumei Yao, Min Wang, Fengjun Ca. Nanofibrous bicomponent scaffolds for the dual delivery of NGF and GDNF: controlled release of growth factors and their biological effects. Journal of materials science. Materials in medicine. vol 32. issue 1. 2021-09-13. PMID:33471206. |
in this study, we have investigated the formation, structure, and characteristics/properties of fibrous bicomponent scaffolds for the dual delivery of glial cell line-derived neurotrophic factor (gdnf) and nerve growth factor (ngf) for peripheral nerve tissue regeneration. |
2021-09-13 |
2023-08-13 |
rat |
| Sumonto Mitra, Giorgio Turconi, Taher Darreh-Shori, Kärt Mätlik, Matilde Aquilino, Maria Eriksdotter, Jaan-Olle Andresso. Increased Endogenous GDNF in Mice Protects Against Age-Related Decline in Neuronal Cholinergic Markers. Frontiers in aging neuroscience. vol 13. 2021-09-04. PMID:34475820. |
glial cell line-derived neurotrophic factor (gdnf) is known to modulate and enhance the dopamine system. |
2021-09-04 |
2023-08-13 |
mouse |
| Alireza Torfeh, Zohreh Abdolmaleki, Sepideh Nazarian, Seyed Hamed Shirazi Beheshtih. Modafinil-coated nanoparticle increases expressions of brain-derived neurotrophic factor, glial cell line-derived neurotrophic factor and neuronal nuclear protein, and protects against middle cerebral artery occlusion-induced neuron apoptosis in the rat hippocampus. Anatomical record (Hoboken, N.J. : 2007). vol 304. issue 9. 2021-09-03. PMID:33345406. |
infarct volume, brain-derived neurotrophic factor (bdnf), glial cell line-derived neurotrophic factor (gdnf), neuronal nuclear protein (neun) and caspase-3 and, caspase-8 as apoptotic genes were measured in the hippocampal ca1 region. |
2021-09-03 |
2023-08-13 |
human |
| Roger A Barker, Anders Björklund, Don M Gash, Alan Whone, Amber Van Laar, Jeffrey H Kordower, Krystof Bankiewicz, Karl Kieburtz, Mart Saarma, Sigrid Booms, Henri J Huttunen, Adrian P Kells, Massimo S Fiandaca, A Jon Stoessl, David Eidelberg, Howard Federoff, Merja H Voutilainen, David T Dexter, Jamie Eberling, Patrik Brundin, Lyndsey Isaacs, Leah Mursaleen, Eros Bresolin, Camille Carroll, Alasdair Coles, Brian Fiske, Helen Matthews, Codrin Lungu, Richard K Wyse, Simon Stott, Anthony E Lan. GDNF and Parkinson's Disease: Where Next? A Summary from a Recent Workshop. Journal of Parkinson's disease. vol 10. issue 3. 2021-08-19. PMID:32508331. |
the concept of repairing the brain with growth factors has been pursued for many years in a variety of neurodegenerative diseases including primarily parkinson's disease (pd) using glial cell line-derived neurotrophic factor (gdnf). |
2021-08-19 |
2023-08-13 |
Not clear |
| Xin Zhao, Bo Li, Xiangchen Guan, Guiyin Sun, Mingzhe Zhang, Weihua Zhang, Junfeng Xu, Xiaoping Re. Peg-Enhanced Behavioral Recovery After Sciatic Nerve Transection and Either Suturing Or Sleeve Conduit Deployment in Rats. Journal of investigative surgery : the official journal of the Academy of Surgical Research. vol 34. issue 5. 2021-08-18. PMID:31438740. |
histology comprised standard hematoxylin/eosin staining, electron microscopy and glial cell line-derived neurotrophic factor (gdnf) immunohistochemistry. |
2021-08-18 |
2023-08-13 |
rat |
| Wen-Sheng Shen, Cun-Feng Li, Zhi-Shui Zhou, Nan-Nan Zhai, Lu-Ping Pa. MicroRNA-204 silencing relieves pain of cervical spondylotic radiculopathy by targeting GDNF. Gene therapy. vol 27. issue 6. 2021-08-18. PMID:31819204. |
glial cell line-derived neurotrophic factor (gdnf) is a potent neurotrophic factor for motoneurons. |
2021-08-18 |
2023-08-13 |
rat |
| N A Gavrilova, S A Borzenok, A V Revishchin, O E Tishchenko, D S Ostrovkiy, M M Bobrova, L A Safonova, A E Efimov, O I Agapova, M B Agammedov, G V Pavlova, I I Agapo. The effect of biodegradable silk fibroin-based scaffolds containing glial cell line-derived neurotrophic factor (GDNF) on the corneal regeneration process. International journal of biological macromolecules. vol 185. 2021-08-18. PMID:34119551. |
the effect of biodegradable silk fibroin-based scaffolds containing glial cell line-derived neurotrophic factor (gdnf) on the corneal regeneration process. |
2021-08-18 |
2023-08-13 |
mouse |
| Jin Gao, Deng-Li Qin, Chuan-Xi Tang, Xiao-Yu Kang, Cheng-Jie Song, Can-Tang Zhan. Smarcd1 antagonizes the apoptosis of injured MES23.5 DA cells by enhancing the effect of Six2 on GDNF expression. Neuroscience letters. vol 760. 2021-08-17. PMID:34233203. |
glial cell line-derived neurotrophic factor (gdnf) played critical roles in the survival and repair of dopaminergic (da) neurons. |
2021-08-17 |
2023-08-13 |
Not clear |
| Femke Mathot, Nadia Rbia, Roman Thaler, Allan B Dietz, Andre J van Wijnen, Allen T Bishop, Alexander Y Shi. Gene expression profiles of human adipose-derived mesenchymal stem cells dynamically seeded on clinically available processed nerve allografts and collagen nerve guides. Neural regeneration research. vol 16. issue 8. 2021-08-13. PMID:33433492. |
neurotrophic [nerve growth factor (ngf), glial cell line-derived neurotrophic factor (gdnf), pleiotrophin (ptn), growth associated protein 43 (gap43) and brain-derived neurotrophic factor (bdnf)], myelination [peripheral myelin protein 22 (pmp22) and myelin protein zero (mpz)], angiogenic [platelet endothelial cell adhesion molecule 1 (pecam1/cd31) and vascular endothelial cell growth factor alpha (vegfa)], extracellular matrix (ecm) [collagen type alpha i (col1a1), collagen type alpha iii (col3a1), fibulin 1 (fbln1) and laminin subunit beta 2 (lamb2)] and cell surface marker cluster of differentiation 96 (cd96) gene expression was quantified. |
2021-08-13 |
2023-08-13 |
human |
| Baole Zhang, Xiao Han, Qing Gao, Jie Liu, Saisai Li, Wei Zha, Xiaoyu Wang, Xiaoxiao Guo, Dianshuai Ga. Enhancer II-targeted dsRNA decreases GDNF expression via histone H3K9 trimethylation to inhibit glioblastoma progression. Brain research bulletin. vol 167. 2021-08-11. PMID:33278485. |
glial cell line-derived neurotrophic factor (gdnf) is expressed in both astrocytes and glioblastoma (gbm) cells. |
2021-08-11 |
2023-08-13 |
Not clear |
| Kazuo Yamagat. Astrocytic nutritional dysfunction associated with hypoxia-induced neuronal vulnerability in stroke-prone spontaneously hypertensive rats. Neurochemistry international. vol 138. 2021-07-30. PMID:32579896. |
remarkable differences in glial cell line-derived neurotrophic factor (gdnf) expression and l-serine production were also observed in shrsp/izm-derived astrocytes compared to wky/izm. |
2021-07-30 |
2023-08-13 |
human |
| Hanna Viisanen, Ulpukka Nuotio, Oleg Kambur, Arun Kumar Mahato, Viljami Jokinen, Tuomas Lilius, Wei Li, Hélder A Santos, Mati Karelson, Pekka Rauhala, Eija Kalso, Yulia A Sidorov. Novel RET agonist for the treatment of experimental neuropathies. Molecular pain. vol 16. 2021-07-27. PMID:32811276. |
the glial cell line-derived neurotrophic factor (gdnf) family ligands (gfls) alleviate symptoms of experimental neuropathy, protect and stimulate regeneration of sensory neurons in animal models of neuropathic pain, and restore their functional activity. |
2021-07-27 |
2023-08-13 |
rat |
| Lucía Coll, Silvia S Rodriguez, Rodolfo G Goya, Gustavo R More. A regulatable adenovector system for GDNF and GFP delivery in the rat hippocampus. Neuropeptides. vol 83. 2021-07-16. PMID:32690313. |
gene therapy using neurotrophic factors like glial cell line-derived neurotrophic factor (gdnf) emerges as a promising approach to ameliorate age-related cognitive deficits. |
2021-07-16 |
2023-08-13 |
rat |
| Emma Connolly, David J Morgan, Miriam Franklin, Angela Simpson, Rajesh Shah, Oliver J Brand, Christopher P Jagger, Joshua Casulli, Karishma Mohamed, Aleksander M Grabiec, Tracy Hussel. Neurturin regulates the lung-resident macrophage inflammatory response to viral infection. Life science alliance. vol 3. issue 12. 2021-07-13. PMID:33020210. |
this circuit involves type 1 interferon-induced up-regulation of ret that when combined with the glial cell line-derived neurotrophic factor (gdnf) receptor α2 (gfrα2) allows binding to epithelial-derived nrtn. |
2021-07-13 |
2023-08-13 |
human |
| Tomihisa Niitsu, Yasunori Oda, Keita Idemoto, Kiyomitsu Ota, Jing Liu, Tsuyoshi Sasaki, Michiko Nakazato, Kenji Hashimoto, Masaomi Iy. Association between serum levels of glial cell line-derived neurotrophic factor and inattention in adult patients with attention deficits/hyperactivity disorder. Psychiatry research. vol 296. 2021-07-13. PMID:33385784. |
glial cell line-derived neurotrophic factor (gdnf) may play an important role in attention. |
2021-07-13 |
2023-08-13 |
Not clear |
| Xin-Feng Liu, Chuan-Xi Tang, Lin Zhang, Shu-Yan Tong, Yue Wang, Ayanlaja Abiola Abdulrahman, Guang-Quan Ji, Yue Gao, Dian-Shuai Gao, Bao-Le Zhan. Down-Regulated CUEDC2 Increases GDNF Expression by Stabilizing CREB Through Reducing Its Ubiquitination in Glioma. Neurochemical research. vol 45. issue 12. 2021-07-12. PMID:33125618. |
abnormally high expression of glial cell line-derived neurotrophic factor (gdnf) derived from glioma cells has essential impacts on gliomagenesis and development, but the molecular basis underlying increased gdnf expression in glioma cells remain unclear. |
2021-07-12 |
2023-08-13 |
Not clear |
| Dahae Lee, Yejin Kim, Hyejung Jo, Cheolhyeon Go, Yoojin Jeong, Yoojin Jang, Dongmin Kang, Kwanjin Park, Yoon-Seong Kim, Jae Seung Kan. The Anti-Inflammatory Effect of Aptamin C on House Dust Mite Extract-Induced Inflammation in Keratinocytes via Regulation of IL-22 and GDNF Production. Antioxidants (Basel, Switzerland). vol 10. issue 6. 2021-07-10. PMID:34208021. |
although hdm treatment markedly increased the expression of glial cell line-derived neurotrophic factor (gdnf), which is associated with itching in ad skin lesions, this increase was reduced by aptamin c treatment. |
2021-07-10 |
2023-08-13 |
Not clear |
| Maryam Sharif, Maryam Noroozian, Farshad Hashemia. Do serum GDNF levels correlate with severity of Alzheimer's disease? Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 42. issue 7. 2021-07-09. PMID:33215334. |
a growing body of evidence that glial cell line-derived neurotrophic factor (gdnf) levels are probably involved in pathogenesis and disease course of alzheimer's disease (ad) suggested that its blood levels could potentially be used as a biomarker of ad. |
2021-07-09 |
2023-08-13 |
Not clear |