| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dorota Martysiak-Żurowska, Małgorzata Puta, Bogumiła Kiełbratowska, Aleksandra Wesołowsk. Neurotrophic Factors in Human Milk in Early Lactation and the Effect of Holder and Microwave Pasteurization on Their Concentrations. Journal of pediatric gastroenterology and nutrition. vol 72. issue 6. 2021-07-09. PMID:33976087. |
the objective of this study was to determine the level of brain-derived neurotrophic factor (bdnf) and glial cell line-derived neurotrophic factor (gdnf) in human milk in the first 2 weeks of breast-feeding and compare the effects of holder pasteurization (hop, 62.5 °c, 30 minutes) and microwave pasteurization (mp) at constant temperature (62.5 °c) on the concentraion of both neurotrophic factors (nfs). |
2021-07-09 |
2023-08-13 |
human |
| M Kemal Özbilgin, Serdağ Demirören, Meltem Üçöz, Mustafa Oztatlic. Cyclophosphamide suppresses spermatogenesis in the testis of mice through downregulation of miR-34b and miR-34c. Andrologia. vol 53. issue 7. 2021-07-08. PMID:33900636. |
in this study, we aimed to evaluate the effects of cp-induced testicular toxicity, using glial cell line-derived neurotrophic factor (gdnf), occludin and transforming growth factor beta 3 (tgf-β3) primary antibodies, and mir-34b and mir-34c expressions. |
2021-07-08 |
2023-08-13 |
mouse |
| Anastasiia Kotliarova, Yulia A Sidorov. Glial Cell Line-Derived Neurotrophic Factor Family Ligands, Players at the Interface of Neuroinflammation and Neuroprotection: Focus Onto the Glia. Frontiers in cellular neuroscience. vol 15. 2021-07-06. PMID:34220453. |
this article summarizes available data on the effects of glial cell line derived neurotrophic factor (gdnf) family ligands (gfls), proteins providing trophic support to dopaminergic, sensory, motor and many other neuronal populations, in non-neuronal cells contributing to the development and maintenance of neuropathic pain. |
2021-07-06 |
2023-08-13 |
rat |
| Shulin Li, Yanping Wang, Zhuojun Wang, Lu Chen, Bangjie Zuo, Caixia Liu, Dong Su. Enhanced renoprotective effect of GDNF-modified adipose-derived mesenchymal stem cells on renal interstitial fibrosis. Stem cell research & therapy. vol 12. issue 1. 2021-07-05. PMID:33413640. |
the present study aimed to determine whether glial cell line-derived neurotrophic factor (gdnf)-modified amscs hold an enhanced protective effect on renal fibrosis. |
2021-07-05 |
2023-08-13 |
human |
| Pepin Marshall, Daniel R Garton, Tomi Taira, Vootele Võikar, Carolina Vilenius, Natalia Kulesskaya, Claudio Rivera, Jaan-Olle Andresso. Elevated expression of endogenous glial cell line-derived neurotrophic factor impairs spatial memory performance and raises inhibitory tone in the hippocampus. The European journal of neuroscience. vol 53. issue 8. 2021-06-29. PMID:33481269. |
the mechanisms of pv+ neuron generation and maintenance are not fully understood, yet current evidence suggests that signalling via the glial cell line-derived neurotrophic factor (gdnf) receptor gfrα1 positively modulates the migration and differentiation of pv+ interneurons in the cortex. |
2021-06-29 |
2023-08-13 |
mouse |
| Arun Kumar Mahato, Yulia A Sidorov. Glial cell line-derived neurotrophic factors (GFLs) and small molecules targeting RET receptor for the treatment of pain and Parkinson's disease. Cell and tissue research. vol 382. issue 1. 2021-06-23. PMID:32556722. |
rearranged during transfection (ret), in complex with glial cell line-derived (gdnf) family receptor alpha (gfrα), is the canonical signaling receptor for gdnf family ligands (gfls) expressed in both central and peripheral parts of the nervous system and also in non-neuronal tissues. |
2021-06-23 |
2023-08-13 |
Not clear |
| Christopher R Donnelly, Brian A Pierchal. Plasma membrane localization of the GFL receptor components: a nexus for receptor crosstalk. Cell and tissue research. vol 382. issue 1. 2021-06-23. PMID:32767110. |
the glial cell line-derived neurotrophic factor (gdnf) family ligands (gfls) comprise a group of four homologous and potent growth factors that includes gdnf, neurturin (nrtn), artemin (artn), and persephin (pspn). |
2021-06-23 |
2023-08-13 |
Not clear |
| Kumi Kawai, Masahide Takahash. Intracellular RET signaling pathways activated by GDNF. Cell and tissue research. vol 382. issue 1. 2021-06-23. PMID:32816064. |
physiologically, ret is activated by glial cell line-derived neurotrophic factor (gdnf) ligands that bind to coreceptor gdnf family receptor alphas (gfrαs), leading to ret dimerization. |
2021-06-23 |
2023-08-13 |
human |
| James A Conway, Selvi Ince, Stephanie Black, Edgar R Krame. GDNF/RET signaling in dopamine neurons in vivo. Cell and tissue research. vol 382. issue 1. 2021-06-23. PMID:32870383. |
the glial cell line-derived neurotrophic factor (gdnf) and its canonical receptor ret can signal both in tandem and separately to exert many vital functions in the midbrain dopamine system. |
2021-06-23 |
2023-08-13 |
Not clear |
| Alberto F Cintrón-Colón, Gabriel Almeida-Alves, Alicia M Boynton, John M Spitsberge. GDNF synthesis, signaling, and retrograde transport in motor neurons. Cell and tissue research. vol 382. issue 1. 2021-06-23. PMID:32897420. |
glial cell line-derived neurotrophic factor (gdnf) is a 134 amino acid protein belonging in the gdnf family ligands (gfls). |
2021-06-23 |
2023-08-13 |
rat |
| Alberto F Cintrón-Colón, Gabriel Almeida-Alves, Alicia M Boynton, John M Spitsberge. GDNF synthesis, signaling, and retrograde transport in motor neurons. Cell and tissue research. vol 382. issue 1. 2021-06-23. PMID:32897420. |
gdnf was originally isolated from rat glial cell lines and identified as a neurotrophic factor with the ability to promote dopamine uptake within midbrain dopaminergic neurons. |
2021-06-23 |
2023-08-13 |
rat |
| Ming-Yu Shi, Cheng-Cheng Ma, Fang-Fang Chen, Xiao-Yu Zhou, Xue Li, Chuan-Xi Tang, Lin Zhang, Dian-Shuai Ga. Possible role of glial cell line-derived neurotrophic factor for predicting cognitive impairment in Parkinson's disease: a case-control study. Neural regeneration research. vol 16. issue 5. 2021-06-23. PMID:33229724. |
glial cell line-derived neurotrophic factor (gdnf) plays an important role in the protection of dopaminergic neurons, but there are few reports of the relationship between gdnf and its precursors (α-pro-gdnf and β-pro-gdnf) and cognitive impairment in parkinson's disease. |
2021-06-23 |
2023-08-13 |
human |
| Olesja Bondarenko, Mart Saarm. Neurotrophic Factors in Parkinson's Disease: Clinical Trials, Open Challenges and Nanoparticle-Mediated Delivery to the Brain. Frontiers in cellular neuroscience. vol 15. 2021-06-22. PMID:34149364. |
we shortly summarize clinical trials of four ntfs, glial cell line-derived neurotrophic factor (gdnf), neurturin (nrtn), platelet-derived growth factor (pdgf-bb), and cerebral dopamine neurotrophic factor (cdnf), that were tested in pd patients, focusing mainly on gdnf and cdnf. |
2021-06-22 |
2023-08-13 |
Not clear |
| Rozita Azarniad, Mazdak Razi, Shapour Hasanzadeh, Hassan Malekineja. Experimental diabetes negatively affects the spermatogonial stem cells' self-renewal by suppressing GDNF network interactions. Andrologia. vol 52. issue 9. 2021-06-21. PMID:32539191. |
the present study was done to analyse the time-dependent effects of diabetes on sertoli cells-spermatogonial stem cells' (sscs) network interaction by focusing on glial cell line-derived neurotrophic factor (gdnf) and its special receptors, gfrα1 and c-ret as well as the bcl-6b. |
2021-06-21 |
2023-08-13 |
rat |
| Keihan Ghatreh, Masoumeh Eliyasi, Shahla Alaei, Ghasem Sak. Differentiation potential of adipose tissue-derived mesenchymal stem cells into germ cells with and without growth factors. Andrologia. vol 53. issue 1. 2021-06-21. PMID:33167071. |
this study aimed to culture the adipose tissue-derived mesenchymal stem cells (at-mscs) with and without leukaemia inhibitory factor (lif), glial cell line-derived neurotrophic factor (gdnf), epidermal growth factor (egf) and retinoic acid (ra), and investigate their impact on the differentiation of these cells into germ cells. |
2021-06-21 |
2023-08-13 |
mouse |
| Rong Xu, Julei Wu, Liqin Lang, Jie Hu, Hailiang Tang, Juefeng Xu, Bing Su. Implantation of glial cell line-derived neurotrophic factor-expressing adipose tissue-derived stromal cells in a rat Parkinson's disease model. Neurological research. vol 42. issue 8. 2021-06-15. PMID:32567526. |
in previous studies, the effects of glial cell line-derived neurotrophic factor (gdnf) expressing adipose tissue-derived stromal cells (adscs) on parkinson's disease (pd) models have been studied but have not been elucidated. |
2021-06-15 |
2023-08-13 |
rat |
| Shoujia Sun, Quan Zhang, Man Li, Pan Gao, Kuan Huang, Rajluxmee Beejadhursing, Wei Jiang, Ting Lei, Mingxin Zhu, Kai Sh. GDNF Promotes Survival and Therapeutic Efficacy of Human Adipose-Derived Mesenchymal Stem Cells in a Mouse Model of Parkinson's Disease. Cell transplantation. vol 29. 2021-06-08. PMID:32292068. |
glial cell line-derived neurotrophic factor (gdnf), which encompasses a variety of transforming growth factor beta super family members, has been reported to enhance motor function and exert neuroprotective effects. |
2021-06-08 |
2023-08-13 |
mouse |
| Xiu-Qi Bao, Lu Wang, Han-Yu Yang, Li-Yan Hou, Qing-Shan Wang, Dan Zhan. Induction of glial cell line-derived neurotrophic factor by the squamosamide derivative FLZ in astroglia has neuroprotective effects on dopaminergic neurons. Brain research bulletin. vol 154. 2021-06-07. PMID:31669104. |
glial cell line-derived neurotrophic factor (gdnf) has neurotrophic activity for the survival of dopaminergic neurons, which is under active investigation for parkinson's disease (pd) therapy. |
2021-06-07 |
2023-08-13 |
Not clear |
| Sergei G Kalinichenko, Anatoliy V Korobtsov, Natalya Yu Matveeva, Igor I Pushchi. Structural and chemical changes in glial cells in the rat neocortex induced by constant occlusion of the middle cerebral artery. Acta histochemica. vol 122. issue 5. 2021-06-07. PMID:32622419. |
here, we studied the immunolocalization of glial cell line-derived neurotrophic factor (gdnf), glial fibrillary acidic protein (gfap), ionized calcium-binding adaptor molecule 1 (iba-1), and s-100β in the rat parietal cortex after constant occlusion of the middle cerebral artery. |
2021-06-07 |
2023-08-13 |
rat |
| Sergei G Kalinichenko, Anatoliy V Korobtsov, Natalya Yu Matveeva, Igor I Pushchi. Structural and chemical changes in glial cells in the rat neocortex induced by constant occlusion of the middle cerebral artery. Acta histochemica. vol 122. issue 5. 2021-06-07. PMID:32622419. |
in the penumbra, on days 1-3 after ischemic injury, gdnf immunoreactivity was mainly localized in neurons, while later on (days 8-21) it was mainly constrained to astrocyte glia. |
2021-06-07 |
2023-08-13 |
rat |