| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| HuiLing Chen, TiYun Han, LiPing Gao, DeKui Zhan. The Involvement of Glial Cell-Derived Neurotrophic Factor in Inflammatory Bowel Disease. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research. 2021-11-30. PMID:34846920. |
recent data show that the glial cell line-derived neurotrophic factor (gdnf) promotes ieb function and wound healing. |
2021-11-30 |
2023-08-13 |
Not clear |
| Jawed Akhtar Siddiqui, Ramesh Pothuraju, Parvez Khan, Gunjan Sharma, Sakthivel Muniyan, Parthasarathy Seshacharyulu, Maneesh Jain, Mohd Wasim Nasser, Surinder Kumar Batr. Pathophysiological role of growth differentiation factor 15 (GDF15) in obesity, cancer, and cachexia. Cytokine & growth factor reviews. 2021-11-27. PMID:34836750. |
recently, research on gdf15 and gdf15-associated signaling has accelerated due to the identification of the gdf15 receptor: glial cell line-derived neurotrophic factor (gdnf) family receptor α-like (gfral). |
2021-11-27 |
2023-08-13 |
Not clear |
| Dzhirgala V Shamadykova, Dmitry Y Panteleev, Nadezhda N Kust, Ekaterina A Savchenko, Ekaterina Y Rybalkina, Alexander V Revishchin, Galina V Pavlov. Neuroinductive properties of mGDNF depend on the producer, E. Coli or human cells. PloS one. vol 16. issue 10. 2021-11-25. PMID:34634077. |
the glial cell line-derived neurotrophic factor (gdnf) is involved in the survival of dopaminergic neurons. |
2021-11-25 |
2023-08-13 |
mouse |
| Zhe Chen, Hai-Bin Tang, Jun-Jun Kang, Zi-Yi Chen, Yan-Ling Li, Qing-Yu Fan, Lei Zhang, Yu-Hong Song, Gui-Lian Zhang, Hong Fa. Necroptotic astrocytes induced neuronal apoptosis partially through EVs-derived pro-BDNF. Brain research bulletin. vol 177. 2021-11-18. PMID:34555432. |
considering the nutritive and supportive roles of astrocytes, we first examined the neurotrophic phenotype of necroptotic astrocytes with focus on glial cell line-derived neurotrophic factor (gdnf) and brain-derived neurotrophic factor (bdnf), two important neurotrophic factors, and it was unexpectedly found that the expression of gdnf and bdnf were up-regulated in necroptotic astrocytes in vitro. |
2021-11-18 |
2023-08-13 |
Not clear |
| Ha Zhu, Mingyan Huang, Jianhua Luo, Xinpei Ji, Qiuyan Li. Deficiency of GFRα1 promotes hepatocellular carcinoma progression but enhances oxaliplatin-mediated anti-tumor efficacy. Pharmacological research. vol 172. 2021-11-16. PMID:34391932. |
gfrα1, the receptor for glial cell line-derived neurotrophic factor (gdnf), has been demonstrated to be predominantly expressed in adult liver tissue. |
2021-11-16 |
2023-08-13 |
mouse |
| Ryota Araki, Hayato Tachioka, Ayami Kita, Hironori Fujiwara, Kazufumi Toume, Kinzo Matsumoto, Takeshi Yab. Kihito prevents corticosterone-induced brain dysfunctions in mice. Journal of traditional and complementary medicine. vol 11. issue 6. 2021-11-13. PMID:34765515. |
hippocampal cell survival, the number of hippocampal new-born immature neurons, hippocampal and accumbal dendritic spine density and mrna levels for neurotrophic factors such as glial cell line-derived neurotrophic factor (gdnf) were decreased in cort-treated mice without kit treatment. |
2021-11-13 |
2023-08-13 |
mouse |
| Dennis Klein, Xidi Yuan, Eva Maria Weiß, Rudolf Martin. Physical exercise mitigates neuropathic changes in an animal model for Charcot-Marie-Tooth disease 1X. Experimental neurology. vol 343. 2021-11-09. PMID:34153322. |
this myelin-preserving effect of limited exercise was accompanied by an elevated expression of brain-derived neurotrophic factor (bdnf) in peripheral nerves, while the expression of other trophic factors like neuregulin-1, glial cell line-derived neurotrophic factor (gdnf) or insulin-like growth factor 1 (igf-1) were not influenced by any mode of exercise. |
2021-11-09 |
2023-08-13 |
mouse |
| Pouya Khodamoradi, Amir Amniattalab, Siamak Alizade. Overexpression of GDNF and FGF-1 in Canine Benign Prostatic Hyperplasia: Evidence for a Pathogenetic Role of Neural Growth Factor. Journal of comparative pathology. vol 182. 2021-11-08. PMID:33494907. |
prostate cells from dogs with bph (n = 13) had a significantly higher intensity of cytoplasmic immunolabelling with antibodies against glial cell line-derived neurotrophic factor (gdnf), cytokeratin (ck) ae1/ae3, vimentin, fibroblast growth factor-1 (fgf-1) and prostate-specific antigen (psa), compared with normal prostate glands (n = 20) (p = 0.001), except for psa, which was negative in both normal and bph affected prostates. |
2021-11-08 |
2023-08-13 |
Not clear |
| Guillem Mòdol-Caballero, Belén García-Lareu, Mireia Herrando-Grabulosa, Sergi Verdés, Rubén López-Vales, Gemma Pagès, Miguel Chillón, Xavier Navarro, Assumpció Bosc. Specific Expression of Glial-Derived Neurotrophic Factor in Muscles as Gene Therapy Strategy for Amyotrophic Lateral Sclerosis. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 18. issue 2. 2021-11-02. PMID:33786805. |
glial cell line-derived neurotrophic factor (gdnf) is a powerful neuroprotective growth factor. |
2021-11-02 |
2023-08-13 |
mouse |
| Julia Konovalova, Dmytro Gerasymchuk, Sergio Navarette Arroyo, Sven Kluske, Francesca Mastroianni, Alba Vargas Pereyra, Andrii Domansky. Human-Specific Regulation of Neurotrophic Factors MANF and CDNF by microRNAs. International journal of molecular sciences. vol 22. issue 18. 2021-10-29. PMID:34575854. |
their dysregulation was demonstrated in multiple pathological processes and their ability to modulate levels of other neurotrophic factors, glial cell line-derived neurotrophic factor (gdnf) and brain-derived neurotrophic factor (bdnf), was previously reported. |
2021-10-29 |
2023-08-13 |
Not clear |
| Jian Zeng, Huan Yu, Hua-Tian Ga. Glial cell line-derived neurotrophic factor ameliorates dextran sulfate sodium-induced colitis in mice via a macrophage-mediated pathway. International immunopharmacology. vol 100. 2021-10-27. PMID:34543979. |
glial cell line-derived neurotrophic factor (gdnf) has been reported to protect mice from intestinal inflammation, but its anti-inflammatory mechanisms are poorly understood. |
2021-10-27 |
2023-08-13 |
mouse |
| Yulia Michailov, Ali AbuMadighem, Eitan Lunenfeld, Joseph Kapelushnik, Mahmoud Huleihe. Granulocyte Colony-Stimulating Factor Restored Impaired Spermatogenesis and Fertility in an AML-Chemotherapy Mice Model. International journal of molecular sciences. vol 22. issue 20. 2021-10-26. PMID:34681817. |
our results showed a significant decrease in the expression of glial cell line-derived neurotrophic factor (gdnf), macrophage colony-stimulating factor (mcsf) and stem cell factor (scf) under aml conditions, but not under cytarabine treatment compared to control. |
2021-10-26 |
2023-08-13 |
mouse |
| Katharina Faust, Peter Vajkoczy, Bai Xi, Daniel Harnac. The Effects of Deep Brain Stimulation of the Subthalamic Nucleus on Vascular Endothelial Growth Factor, Brain-Derived Neurotrophic Factor, and Glial Cell Line-Derived Neurotrophic Factor in a Rat Model of Parkinson's Disease. Stereotactic and functional neurosurgery. vol 99. issue 3. 2021-10-22. PMID:33152730. |
those may be mediated through neurotrophic factors (nfs) like vascular endothelial growth factor (vegf), brain-derived neurotrophic factor (bdnf), and glial cell line-derived neurotrophic factor (gdnf). |
2021-10-22 |
2023-08-13 |
rat |
| Victoria C de Leeuw, Conny T M van Oostrom, Remco H S Westerink, Aldert H Piersma, Harm J Heusinkveld, Ellen V S Hesse. An efficient neuron-astrocyte differentiation protocol from human embryonic stem cell-derived neural progenitors to assess chemical-induced developmental neurotoxicity. Reproductive toxicology (Elmsford, N.Y.). vol 98. 2021-10-20. PMID:32931842. |
modulating the ratio of astrocytes and neurons through different growth factors including glial cell line-derived neurotrophic factor (gdnf), brain-derived neurotrophic factor (bdnf), and ciliary neurotrophic factor (cntf) did not compromise the ability to develop spontaneous electrical activity. |
2021-10-20 |
2023-08-13 |
human |
| Xue-Ming Zhan. GFRα-1 is a reliable marker of bovine gonocytes/undifferentiated spermatogonia: A mini-review. Anatomia, histologia, embryologia. vol 50. issue 1. 2021-10-19. PMID:32761645. |
the glial cell line-derived neurotrophic factor (gdnf) family receptor alpha-1 (gfrα-1) is a conserved marker of the gonocytes/sscs in multiple species including rodents, primates and human; however, its expression in bovine gonocytes/sscs is debated. |
2021-10-19 |
2023-08-13 |
human |
| Keita Idemoto, Tomihisa Niitsu, Tatsuki Hata, Tamaki Ishima, Sumiko Yoshida, Kotaro Hattori, Tadasu Horai, Ikuo Otsuka, Hidenaga Yamamori, Shigenobu Toda, Yosuke Kameno, Kiyomitsu Ota, Yasunori Oda, Atsushi Kimura, Tasuku Hashimoto, Norio Mori, Mitsuru Kikuchi, Yoshio Minabe, Ryota Hashimoto, Akitoyo Hishimoto, Kazuyuki Nakagome, Kenji Hashimoto, Masaomi Iy. Serum levels of glial cell line-derived neurotrophic factor as a biomarker for mood disorders and lithium response. Psychiatry research. vol 301. 2021-10-14. PMID:33990070. |
glial cell line-derived neurotrophic factor (gdnf) plays an important role in the pathophysiology of neuropsychiatric disorders. |
2021-10-14 |
2023-08-13 |
human |
| Pramod S Terse, Adrian P Kells, Patricia Noker, J Fraser Wright, Krystof S Bankiewic. Safety Assessment of AAV2-hGDNF Administered Via Intracerebral Injection in Rats for Treatment of Parkinson's Disease. International journal of toxicology. vol 40. issue 1. 2021-10-11. PMID:33131343. |
glial cell line-derived neurotrophic factor (gdnf) is a potent neuroprotective biologic in parkinson's disease models. |
2021-10-11 |
2023-08-13 |
rat |
| Asima Karim, Tahir Muhammad, Rizwan Qaisa. Prediction of Sarcopenia Using Multiple Biomarkers of Neuromuscular Junction Degeneration in Chronic Obstructive Pulmonary Disease. Journal of personalized medicine. vol 11. issue 9. 2021-10-01. PMID:34575696. |
we evaluated the circulating biomarkers of nmj degradation, including c-terminal agrin fragment -22 (caf22), brain-derived neurotrophic factor (bdnf), and glial cell line-derived neurotrophic factor (gdnf) as predictors of sarcopenia in copd during pulmonary rehabilitation (pr). |
2021-10-01 |
2023-08-13 |
Not clear |
| Mirit Liran, Nofar Rahamim, Dorit Ron, Segev Bara. Growth Factors and Alcohol Use Disorder. Cold Spring Harbor perspectives in medicine. vol 10. issue 12. 2021-09-28. PMID:31964648. |
specifically, we focus on the brain-derived neurotrophic factor (bdnf), glial cell line-derived neurotrophic factor (gdnf), fibroblast growth factor 2 (fgf2), and insulin growth factor 1 (igf-1). |
2021-09-28 |
2023-08-13 |
Not clear |
| Joanne E Kearon, S C Kocherry, D Zoumboulakis, D Rivera, S R Lourenssen, M G Blennerhasset. GDNF requires HIF-1α and RET activation for suppression of programmed cell death of enteric neurons by metabolic challenge. Molecular and cellular neurosciences. vol 115. 2021-09-23. PMID:34273501. |
in the animal model of tnbs-induced colitis, an influx of immune cells causes early neuron death in the neuromuscular layers, followed by axonal outgrowth from surviving neurons associated with upregulation of the neurotrophin gdnf (glial cell line-derived neurotrophic factor). |
2021-09-23 |
2023-08-13 |
rat |