| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sergei G Kalinichenko, Igor I Pushchin, Natalya Yu Matveev. Neurotoxic and cytoprotective mechanisms in the ischemic neocortex. Journal of chemical neuroanatomy. 2023-01-05. PMID:36603664. |
heterogeneous distribution of the bdnf, nt-3, and gdnf immunoreactivity is concordant with the selective response of different types of cortical neurons and glia to ischemic injury and allows mapping the position of viable neurons. |
2023-01-05 |
2023-08-14 |
Not clear |
| Fahimeh Mohseni, Raheleh Rafaiee, Leila Rezaeian, Mohammad Niroumand Sarvandani, Hamid Kalalian Moghadda. Berberine hydrochloride improves cognitive deficiency through hippocampal up-regulation of neurotrophins following inhalant self-administration of methamphetamine. Iranian journal of basic medical sciences. vol 26. issue 1. 2023-01-03. PMID:36594063. |
due to the aim of the present study which is to investigate the influence of ber administration on meth-induced cognitive deficits, we investigated neurotrophin signaling including brain-derived neurotrophic factor (bdnf) and glial cell line-derived neurotrophic factor (gdnf) as a possible mechanism by which ber exerts its cognitive improvement influences. |
2023-01-03 |
2023-08-14 |
Not clear |
| Jue Wang, Sai Gu, Bo Qi. Overexpression of microRNA-211 in Functional Dyspepsia via Downregulation of the Glial Cell Line-Derived Neurotrophic Factor (GDNF) by Increasing Phosphorylation of p38 MAPK Pathway. Canadian journal of gastroenterology & hepatology. vol 2022. 2022-12-26. PMID:36569394. |
overexpression of microrna-211 in functional dyspepsia via downregulation of the glial cell line-derived neurotrophic factor (gdnf) by increasing phosphorylation of p38 mapk pathway. |
2022-12-26 |
2023-08-14 |
Not clear |
| Maria Aleksandrovna Davleeva, Ravil Rasimovich Garifulin, Farid Vagizovich Bashirov, Andrei Aleksandrovich Izmailov, Leniz Faritovich Nurullin, Ilnur Ildusovich Salafutdinov, Dilara Zilbarovna Gatina, Dmitrij Nikolaevich Shcherbinin, Andrei Aleksandrovich Lysenko, Irina Leonidovna Tutykhina, Maksim Mikhailovich Shmarov, Rustem Robertovich Islamo. Molecular and cellular changes in the post-traumatic spinal cord remodeling after autoinfusion of a genetically-enriched leucoconcentrate in a mini-pig model. Neural regeneration research. vol 18. issue 7. 2022-12-26. PMID:36571355. |
in the present study, the efficacy of the intravenous infusion of an autologous genetically-enriched leucoconcentrate simultaneously producing recombinant vascular endothelial growth factor (vegf), glial cell line-derived neurotrophic factor (gdnf), and neural cell adhesion molecule (ncam) was evaluated with regard to the molecular and cellular changes in remodeling of the spinal cord tissue at the site of damage in a model of mini-pigs with moderate spinal cord injury. |
2022-12-26 |
2023-08-14 |
Not clear |
| Maria Rachele Ceccarini, Veronica Ceccarelli, Michela Codini, Katia Fettucciari, Mario Calvitti, Samuela Cataldi, Elisabetta Albi, Alba Vecchini, Tommaso Beccar. The Polyunsaturated Fatty Acid EPA, but Not DHA, Enhances Neurotrophic Factor Expression through Epigenetic Mechanisms and Protects against Parkinsonian Neuronal Cell Death. International journal of molecular sciences. vol 23. issue 24. 2022-12-23. PMID:36555817. |
in this context, bdnf (brain-derived neurotrophic factor) and gdnf (glial cell line-derived neurotrophic factor) have a pivotal role because they are both involved in neuron differentiation, survival, and synaptogenesis. |
2022-12-23 |
2023-08-14 |
Not clear |
| A V Revishchin, V V Parshina, G V Pavlov. [The role of glial cell line-derived neurotrophic factor isoforms in human glial tumors]. Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko. vol 86. issue 6. 2022-12-19. PMID:36534631. |
glial cell line-derived neurotrophic factor (gdnf) has a wide range of actions and positively affects viability, proliferative activity and migratory ability of cells in nervous system. |
2022-12-19 |
2023-08-14 |
human |
| Matthew T Rocco, Asad S Akhter, Debra J Ehrlich, Gretchen C Scott, Codrin Lungu, Vikas Munjal, Anthony Aquino, Russell R Lonser, Massimo S Fiandaca, Mark Hallett, John D Heiss, Krystof S Bankiewic. Long-term safety of MRI-guided administration of AAV2-GDNF and gadoteridol in the putamen of individuals with Parkinson's disease. Molecular therapy : the journal of the American Society of Gene Therapy. vol 30. issue 12. 2022-12-15. PMID:35957524. |
direct putaminal infusion of adeno-associated virus vector (serotype 2) (aav2) containing the human glial cell line-derived neurotrophic factor (gdnf) transgene was studied in a phase i clinical trial of participants with advanced parkinson's disease (pd). |
2022-12-15 |
2023-12-17 |
human |
| M Carmen Ruiz-Cantero, Elsa Cortés-Montero, Aakanksha Jain, Ángeles Montilla-García, Inmaculada Bravo-Caparrós, Jaehoon Shim, Pilar Sánchez-Blázquez, Clifford J Woolf, José M Baeyens, Enrique J Cobo. Sigma-1 receptor curtails endogenous opioid analgesia during sensitization of TRPV1 nociceptors. British journal of pharmacology. 2022-12-08. PMID:36478100. |
while prostaglandin e2 (pge2) and nerve growth factor (ngf) sensitize peptidergic c-nociceptors (trpv1+), glial cell line-derived neurotrophic factor (gdnf) sensitizes non-peptidergic c-neurons (ib4+). |
2022-12-08 |
2023-08-14 |
Not clear |
| Katherine Lloyd, Michael Lawton, Alan Whon. Practically Defined Off-State Dyskinesia Following Repeated Intraputamenal Glial Cell Line-Derived Neurotrophic Factor Administration. Movement disorders : official journal of the Movement Disorder Society. 2022-11-29. PMID:36444971. |
we recently showed that by employing an enhanced drug-delivery approach, repeated administration of glial cell line-derived neurotrophic factor (gdnf) can produce a spatially distributed increased |
2022-11-29 |
2023-08-14 |
Not clear |
| Apostolos Mikroulis, Eliška Waloschková, Johan Bengzon, David Woldbye, Lars H Pinborg, Bo Jespersen, Anna Sanchez Avila, Zsofia I Laszlo, Christopher Henstridge, Marco Ledri, Merab Kokai. GDNF Increases Inhibitory Synaptic Drive on Principal Neurons in the Hippocampus via Activation of the Ret Pathway. International journal of molecular sciences. vol 23. issue 21. 2022-11-11. PMID:36361981. |
glial cell line-derived neurotrophic factor (gdnf) has been shown to counteract seizures when overexpressed or delivered into the brain in various animal models of epileptogenesis or chronic epilepsy. |
2022-11-11 |
2023-08-14 |
mouse |
| Wei Liu, Jiaxi Liu, Jie Gao, Xiaoxu Duan, Lifeng Zhan. Effects of Subchronic Aluminum Exposure on Learning, Memory, and Neurotrophic Factors in Rats. Neurotoxicity research. 2022-11-07. PMID:36342585. |
with hematoxylin and eosin staining, western blot, immunofluorescence, and rt-pcr, the morphology of nerve cells in the hippocampus of rat brain were observed, and the levels of activator protein-1 (ap-1) gene and protein, nerve growth factor (ngf), neurotrophin-3 (nt3), glial cell line-derived neurotrophic factor (gdnf), and brain-derived neurotrophic factor (bdnf) gene and protein level, etc. |
2022-11-07 |
2023-08-14 |
human |
| Seydanur Avci, Sukran Gunaydin, Neziha Senem Ari, Emine Karaca Sulukoglu, Ozlem Erol Polat, Ibrahim Gecili, Yesim Yeni, Aysegul Yilmaz, Sidika Genc, Ahmet Hacimuftuoglu, Serkan Yildirim, Muhammed Yasser Mokresh, Damla Gul Findik, Aristidis Tsatsakis, Denisa Margina, Konstantinos Tsarouhas, David R Wallace, Ali Taghizadehghalehjough. Cerebrolysin Alleviating Effect on Glutamate-Mediated Neuroinflammation Via Glutamate Transporters and Oxidative Stress. Journal of molecular neuroscience : MN. 2022-11-05. PMID:36333611. |
cerebrolysin is a mixture of enzymatically treated peptides derived from pig brain including neurotrophic factors, like brain-derived neurotrophic factor (bdnf), glial cell line-derived neurotrophic factor (gdnf), nerve growth factor (ngf), and ciliary neurotrophic factor (cntf). |
2022-11-05 |
2023-08-14 |
Not clear |
| Pablo Vicente Torres-Ortega, Rubén Del Campo-Montoya, Daniel Plano, Jacobo Paredes, Javier Aldazabal, María-Rosario Luquin, Enrique Santamaría, Carmen Sanmartín, María J Blanco-Prieto, Elisa Garbay. Encapsulation of MSCs and GDNF in an Injectable Nanoreinforced Supramolecular Hydrogel for Brain Tissue Engineering. Biomacromolecules. 2022-10-26. PMID:36288499. |
the co-administration of glial cell line-derived neurotrophic factor (gdnf) and mesenchymal stem cells (mscs) in hydrogels (hgs) has emerged as a powerful strategy to enhance the efficient integration of transplanted cells in parkinson's disease (pd). |
2022-10-26 |
2023-08-14 |
Not clear |
| Rafał Staszkiewicz, Dorian Gładysz, Marcin Gralewski, Michał Garczarek, Marcin Gadzieliński, Beniamin Oskar Grabare. Pathomechanism of the IVDs degeneration and the Role of Neurotrophic Factors and Concentration of Selected Elements in Genesis of Low Back Pain. Current pharmaceutical biotechnology. 2022-10-25. PMID:36281863. |
the above-mentioned mediators of an inflammatory condition contribute to an increase in the expression of brain-derived neurotrophic factor (bdnf) and glial cell derived neurotrophic factor (gdnf) in mast cells and chondrocytes, as well as to the descending transport of these mediators along the nerve endings. |
2022-10-25 |
2023-08-14 |
human |
| Luyu Ding, Yifan Wu, Lingtao Kong, Jiaze Sun, Fangru Qu, Kaiqi Xin, Anqi Yang, Xintong Yan, Yihui Lu, Xiaowei Jiang, Yanqing Tang, Feng W. Gender differences in plasma glial cell line-derived neurotrophic factor levels of patients with bipolar disorder. Journal of affective disorders. 2022-10-02. PMID:36183819. |
the glial cell line-derived neurotrophic factor (gdnf) has an important role in neurons and is closely associated with psychiatric disorders. |
2022-10-02 |
2023-08-14 |
Not clear |
| Wei Xu, Zhuofeng Ding, Zongbin Song, Jian Wang, Jie Zhang, Wangyuan Zo. Overexpression of GDNF in Spinal Cord Attenuates Morphine Analgesic Tolerance in Rats with Bone Cancer Pain. Brain sciences. vol 12. issue 9. 2022-09-23. PMID:36138924. |
our previous study indicated that spinal glial cell line-derived neurotrophic factor (gdnf) exerts analgesic effects in rats with bcp. |
2022-09-23 |
2023-08-14 |
rat |
| Simon Musyoka Mwangi, Ge Li, Arun Balasubramaniam, Didier Merlin, Paul A Dawson, Young C Jang, C Michael Hart, Mark J Czaja, Shanthi Srinivasa. Glial cell derived neurotrophic factor prevents western diet and palmitate-induced hepatocyte oxidative damage and death through SIRT3. Scientific reports. vol 12. issue 1. 2022-09-23. PMID:36151131. |
in this study we investigated the mechanisms involved in the induction of oxidative stress and impairment of mitochondrial quality control and mitophagy in hepatocytes by the saturated fatty acid palmitate and western diet feeding in mice and if their harmful effects could be reversed by the neurotrophic factor glial cell derived neurotrophic factor (gdnf). |
2022-09-23 |
2023-08-14 |
mouse |
| Mikhail S Zinchuk, Alla B Guekht, Tatiana A Druzhkova, Natalia V Gulyaeva, Alexander A Shpa. Glial cell line-derived neurotrophic factor (GDNF) in blood serum and lacrimal fluid of patients with a current depressive episode. Journal of affective disorders. 2022-09-18. PMID:36116600. |
glial cell line-derived neurotrophic factor (gdnf) in blood serum and lacrimal fluid of patients with a current depressive episode. |
2022-09-18 |
2023-08-14 |
Not clear |
| Robert H Baloh, J Patrick Johnson, Pablo Avalos, Peggy Allred, Soshana Svendsen, Genevieve Gowing, Kristina Roxas, Amanda Wu, Becky Donahue, Sheryl Osborne, George Lawless, Brandon Shelley, Koral Wheeler, Carolyn Prina, Dana Fine, Tami Kendra-Romito, Haniah Stokes, Vicki Manoukian, Abirami Muthukumaran, Leslie Garcia, Maria G Bañuelos, Marlesa Godoy, Catherine Bresee, Hong Yu, Doniel Drazin, Lindsey Ross, Robert Naruse, Harish Babu, Eric A Macklin, Ashley Vo, Ashraf Elsayegh, Warren Tourtellotte, Marcel Maya, Matthew Burford, Frank Diaz, Chirag G Patil, Richard A Lewis, Clive N Svendse. Transplantation of human neural progenitor cells secreting GDNF into the spinal cord of patients with ALS: a phase 1/2a trial. Nature medicine. 2022-09-05. PMID:36064599. |
dysfunctional astrocytes may contribute to disease and glial cell line-derived neurotrophic factor (gdnf) can be protective. |
2022-09-05 |
2023-08-14 |
human |
| Xu-Ping Jiang, Yao-Xiang Sun, Bin Qiao, Wen-Jiao Zhu, Yu-Jiao Chu, Miao-Miao Sun, Rui-Jie Tang, Tie-Liang Ma, Zhi-An Tan. Youjing granules ameliorate spermatogenesis in rats through regulating the prolifereation of spermatogonial stem cells. Chinese journal of natural medicines. vol 20. issue 8. 2022-08-28. PMID:36031230. |
results indicated that yg increased the expression of self-renewal and proliferation-related molecules such as glial cell line derived neurotrophic factor (gdnf) and fibroblast growth factor-2 (fgf2), and improved the quality of sperm and the proliferation of sscs. |
2022-08-28 |
2023-08-14 |
mouse |