| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y On. EEG changes with aging in adults with Down syndrome. The Japanese journal of psychiatry and neurology. vol 47. issue 1. 1993-11-16. PMID:8411794. |
the slowing of alpha rhythm in the older ds subjects accompanied an increase of slow activity of 6-8 hz, but did not relate to the deterioration of activities of daily life (adl) as estimated by the gbs score. |
1993-11-16 |
2023-08-12 |
human |
| M Canessa, J R Romero, N Ruiz-Opazo, V L Herrer. The alpha 1 Na(+)-K+ pump of the Dahl salt-sensitive rat exhibits altered Na+ modulation of K+ transport in red blood cells. The Journal of membrane biology. vol 134. issue 2. 1993-10-28. PMID:8411114. |
the properties of the alpha 1 na(+)-k+ pump were compared in dahl salt-sensitive (ds) and salt-resistant (dr) strains by measuring ouabain-sensitive fluxes (mmol/liter cell x hr = fu, mean +/- se) in red blood cells (rbcs) and varying internal (i) and external (o) na+ and k+ concentrations. |
1993-10-28 |
2023-08-12 |
rat |
| M Oda, R Hakamada, K Ono, M Higurash. A seroimmunological analysis of Down syndrome. Gerontology. vol 39 Suppl 1. 1993-10-07. PMID:8365667. |
six tumor markers were also assayed in the serum from ds patients and the serum concentration of alpha-1-acid glycoprotein (alpha 1-agp) and immunosuppressive acidic protein, an analogous glycoprotein of alpha 1-agp, were significantly higher than those of the control group. |
1993-10-07 |
2023-08-12 |
Not clear |
| P Locci, C Lilli, L Marinucci, T Baroni, F Pezzetti, E Becchett. Embryonic skin fibroblasts release TGF alpha and TGF beta able to influence synthesis and secretion of GAG. Cellular and molecular biology (Noisy-le-Grand, France). vol 39. issue 4. 1993-08-13. PMID:8329981. |
in particular, tgf beta stimulates a marked increase of cs and ds, tgf alpha of ha and ds in the medium. |
1993-08-13 |
2023-08-12 |
chicken |
| M Murphy, R M Insoft, L Pike-Nobile, K S Derbin, L B Epstei. Overexpression of LFA-1 and ICAM-1 in Down syndrome thymus. Implications for abnormal thymocyte maturation. Journal of immunology (Baltimore, Md. : 1950). vol 150. issue 12. 1993-07-20. PMID:8099939. |
ds thymocytes also showed significantly higher levels of lfa-1 alpha expression (p < or = 0.05), which is consistent with findings that surface expression of the lfa-1 alpha chain is dependent on beta-chain expression. |
1993-07-20 |
2023-08-12 |
human |
| K Carroll, O Elroy-Stein, B Moss, R Jagu. Recombinant vaccinia virus K3L gene product prevents activation of double-stranded RNA-dependent, initiation factor 2 alpha-specific protein kinase. The Journal of biological chemistry. vol 268. issue 17. 1993-07-13. PMID:8099586. |
purified recombinant k3l gene product, pk3r, has potent effects on activation of double-stranded (ds) rna-dependent, initiation factor-2 alpha (eif-2 alpha)-specific protein kinase (pkr) in in vitro reactions. |
1993-07-13 |
2023-08-12 |
human |
| H W Chang, B L Jacob. Identification of a conserved motif that is necessary for binding of the vaccinia virus E3L gene products to double-stranded RNA. Virology. vol 194. issue 2. 1993-06-25. PMID:8099244. |
the e3l gene of vaccinia virus encodes the double-stranded (ds) rna binding proteins p20 and p25 that exhibit inhibitory activity for the ifn-induced, p1/elf-2 alpha protein kinase. |
1993-06-25 |
2023-08-12 |
human |
| A Nishi, G Celsi, A Aperi. High-salt diet upregulates activity and mRNA of renal Na(+)-K(+)-ATPase in Dahl salt-sensitive rats. The American journal of physiology. vol 264. issue 3 Pt 2. 1993-04-22. PMID:8384412. |
the activity of na(+)-k(+)-atpase and the content of alpha 1- and beta-protein in cortical homogenate were similar in ds and dr rats on both ns and hs diets. |
1993-04-22 |
2023-08-12 |
rat |
| Y Ono, H Yoshida, Y Momotani, F Yoshimasu, Y Higash. Age-related changes in occipital alpha rhythm of adults with Down syndrome. The Japanese journal of psychiatry and neurology. vol 46. issue 3. 1993-02-22. PMID:1487850. |
the frequencies of occipital alpha rhythms of ds showed a significant inverse correlation with chronological age, while control and mr did not. |
1993-02-22 |
2023-08-11 |
human |
| Y Ono, H Yoshida, Y Momotani, F Yoshimasu, Y Higash. Age-related changes in occipital alpha rhythm of adults with Down syndrome. The Japanese journal of psychiatry and neurology. vol 46. issue 3. 1993-02-22. PMID:1487850. |
it was considered that a slowing of alpha rhythm was a manifestation of premature aging that occurred in the underdeveloped brains of ds. |
1993-02-22 |
2023-08-11 |
human |
| J T Lutgerink, E van den Akker, I Smeets, D Pachen, P van Dijk, J M Aubry, H Joenje, M V Lafleur, J Retè. Interaction of singlet oxygen with DNA and biological consequences. Mutation research. vol 275. issue 3-6. 1992-11-23. PMID:1383778. |
in agreement with the observed preferential reaction of 1o2 with dg most of the so far sequenced mutations, induced by 1o2 in a 144 bp mutation target sequence inserted in the lacz alpha gene of ss or ds m13mp10 dna, occurred at a g or g/c base pair respectively. |
1992-11-23 |
2023-08-11 |
rat |
| M Böhm, P Gierschik, E Erdman. Quantification of Gi alpha-proteins in the failing and nonfailing human myocardium. Basic research in cardiology. vol 87 Suppl 1. 1992-09-04. PMID:1497577. |
since the quantification of gi alpha-proteins with the pertussis toxin labeling method is hampered by a number of biological and technical factors, gi alpha-proteins were quantified radioimmunologically using the iodinated c-terminus 125i-kenlkdcglf as tracer, purified retinal transducin alpha as standard, and an antiserum (ds 4) raised against the same peptide. |
1992-09-04 |
2023-08-11 |
human |
| G Tononi, M Pompeiano, C Cirell. Effects of local pontine injection of noradrenergic agents on desynchronized sleep of the cat. Progress in brain research. vol 88. 1992-06-16. PMID:1667551. |
the present experiments investigate the effects on ds of the microinjection, into the cat dorsal pontine tegmentum (dpt), of the alpha 2-agonist clonidine (clon), the beta-agonist isoproterenol and the beta-antagonist propranolol. |
1992-06-16 |
2023-08-11 |
cat |
| G Tononi, M Pompeiano, C Cirell. Suppression of desynchronized sleep through microinjection of the alpha 2-adrenergic agonist clonidine in the dorsal pontine tegmentum of the cat. Pflugers Archiv : European journal of physiology. vol 418. issue 5. 1991-10-17. PMID:1679921. |
since locus coeruleus neurons are strongly inhibited by alpha 2-adrenergic agonists like clonidine, this agent would be expected to increase ds. |
1991-10-17 |
2023-08-11 |
cat |
| M Böhm, K Larisch, E Erdmann, M Camps, K Jakobs, P Gierschi. Failure of [32P]ADP-ribosylation by pertussis toxin to determine Gi alpha content in membranes from various human tissues. Improved radioimmunological quantification using the 125I-labelled C-terminal decapeptide of retinal transducin. The Biochemical journal. vol 277 ( Pt 1). 1991-08-21. PMID:1906710. |
gi alpha proteins were determined by competition of solubilized membranes for 125i-kenlkdcglf binding to ds 4 using dilutions of retinal transducin alpha as standard. |
1991-08-21 |
2023-08-11 |
human |
| K Kato, F Suzuki, N Kurobe, K Okajima, N Ogasawara, M Nagaya, T Yamanak. Enhancement of S-100 beta protein in blood of patients with Down's syndrome. Journal of molecular neuroscience : MN. vol 2. issue 2. 1991-04-29. PMID:2150320. |
in order to confirm the expression of gene-dosage effect of s-100 beta in patients with down's syndrome (ds), concentrations of immunoreactive s-100 alpha and s-100 beta proteins were determined in the blood plasma and lymphocytes fraction of the patients and control subjects. |
1991-04-29 |
2023-08-11 |
human |
| K Kato, F Suzuki, N Kurobe, K Okajima, N Ogasawara, M Nagaya, T Yamanak. Enhancement of S-100 beta protein in blood of patients with Down's syndrome. Journal of molecular neuroscience : MN. vol 2. issue 2. 1991-04-29. PMID:2150320. |
however, concentrations of s-100 alpha in blood plasma of ds patients were similar to those of normal subjects. |
1991-04-29 |
2023-08-11 |
human |
| A D Snow, H Mar, D Nochlin, R T Sekiguchi, K Kimata, Y Koike, T N Wigh. Early accumulation of heparan sulfate in neurons and in the beta-amyloid protein-containing lesions of Alzheimer's disease and Down's syndrome. The American journal of pathology. vol 137. issue 5. 1990-12-11. PMID:2146882. |
a monoclonal antibody (hk-249) that recognizes a glucosamine sulfate alpha 1----4 glucuronic acid-containing determinant in heparan sulfate (hs) chains of a basement membrane-derived heparan sulfate proteoglycan identified and immunolocalized hs specifically to the amyloid deposits in neuritic plaques (nps), congophilic angiopathy (ca), as well as in neurofibrillary tangles (nfts) and non-tangle-bearing neurons in the brains of alzheimer's and down's syndrome (ds) patients. |
1990-12-11 |
2023-08-11 |
Not clear |
| V L Herrera, N Ruiz-Opaz. Alteration of alpha 1 Na+,K(+)-ATPase 86Rb+ influx by a single amino acid substitution. Science (New York, N.Y.). vol 249. issue 4972. 1990-10-09. PMID:1975705. |
the r and s alleles of the gene encoding the na+,k(+)-atpase alpha 1 subunit isoform were identified in dahl salt-resistant (dr) and dahl salt-sensitive (ds) rats, respectively. |
1990-10-09 |
2023-08-11 |
rat |
| O Devinsky, S Sato, R A Conwit, M B Schapir. Relation of EEG alpha background to cognitive function, brain atrophy, and cerebral metabolism in Down's syndrome. Age-specific changes. Archives of neurology. vol 47. issue 1. 1990-02-05. PMID:2136791. |
we studied 19 young adults (19 to 37 years old) and 9 older patients (42 to 66 years old) with down's syndrome (ds) and a control group of 13 healthy adults (22 to 38 years old) to investigate the relation of electroencephalographic (eeg) alpha background to cognitive function and cerebral metabolism. |
1990-02-05 |
2023-08-11 |
human |