| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| O Devinsky, S Sato, R A Conwit, M B Schapir. Relation of EEG alpha background to cognitive function, brain atrophy, and cerebral metabolism in Down's syndrome. Age-specific changes. Archives of neurology. vol 47. issue 1. 1990-02-05. PMID:2136791. |
in comparison with the age-matched patients with ds with normal alpha background, older patients with ds with decreased alpha background had dementia, fewer visuospatial skills, decreased attention span, larger third ventricles, and a global decrease in cerebral glucose utilization with parietal hypometabolism. |
1990-02-05 |
2023-08-11 |
human |
| R L Noble, R P Warre. Analysis of blood cell populations, plasma zinc and natural killer cell activity in young children with Down's syndrome. Journal of mental deficiency research. vol 32 ( Pt 3). 1988-10-20. PMID:2971114. |
normal nk activity was observed and cells from ds children were no more sensitive to the augmenting effects of alpha interferon than cells from control children. |
1988-10-20 |
2023-08-11 |
Not clear |
| G Annerén, M Gebre-Medhi. Trace elements and transport proteins in serum of children with Down syndrome and of healthy siblings living in the same environment. Human nutrition. Clinical nutrition. vol 41. issue 4. 1987-10-22. PMID:2442124. |
the ds patients as a group had higher levels of caeruloplasmin (p less than 0.01), haptoglobin (p less than 0.001), orosomucoid (p less than 0.001) and alpha 2-macroglobulin (p less than 0.001) than the healthy controls and compared with their siblings. |
1987-10-22 |
2023-08-11 |
human |
| R W Karr, C Alber, S M Goyert, J Silver, R J Duquesno. The complexity of HLA-DS molecules. A homozygous cell line expresses multiple HLA-DS alpha chains. The Journal of experimental medicine. vol 159. issue 5. 1984-06-18. PMID:6425448. |
the data presented here document for the first time that a dr homozygous cell line expresses at least two ds alpha chains. |
1984-06-18 |
2023-08-12 |
Not clear |
| R W Karr, C Alber, S M Goyert, J Silver, R J Duquesno. The complexity of HLA-DS molecules. A homozygous cell line expresses multiple HLA-DS alpha chains. The Journal of experimental medicine. vol 159. issue 5. 1984-06-18. PMID:6425448. |
the data presented here for the expression of at least two ds alpha chains and the location of the mb1 allodeterminant on only one of multiple ds molecules are in agreement with recent studies at the gene level. |
1984-06-18 |
2023-08-12 |
Not clear |
| A J Sant, S E Cullen, B D Schwart. Identification of a sulfate-bearing molecule associated with HLA class II antigens. Proceedings of the National Academy of Sciences of the United States of America. vol 81. issue 5. 1984-05-02. PMID:6424118. |
the human ia antigens (dr, ds, and sb), determined by genes contained within the hla complex on chromosome 6, are glycoprotein heterodimers consisting of a mr approximately equal to 34,000 alpha chain and a mr approximately equal to 28,000 beta chain. |
1984-05-02 |
2023-08-12 |
human |
| B R Carr, J I Mason, C R Parker, E R Simpso. Effect of prostaglandins on steroid secretion by human fetal adrenal tissue. Steroids. vol 41. issue 5. 1984-02-24. PMID:6318402. |
in contrast, pge2 or pgf2 alpha had little effect on the rate of ds or ps secretion either in the presence or absence of acth. |
1984-02-24 |
2023-08-12 |
human |
| H C Chang, T Moriuchi, J Silve. The heavy chain of human B-cell alloantigen HLA-DS has a variable N-terminal region and a constant immunoglobulin-like region. Nature. vol 305. issue 5937. 1983-12-17. PMID:6415485. |
both dr and ds molecules consist of two noncovalently associated polypeptide chains with molecular weights of 33,000 and 28,000, designated alpha and beta, respectively. |
1983-12-17 |
2023-08-12 |
human |
| H C Chang, T Moriuchi, J Silve. The heavy chain of human B-cell alloantigen HLA-DS has a variable N-terminal region and a constant immunoglobulin-like region. Nature. vol 305. issue 5937. 1983-12-17. PMID:6415485. |
in contrast, both subunits ds alpha and ds beta are structurally variable when ds allotypes are compared. |
1983-12-17 |
2023-08-12 |
human |
| H C Chang, T Moriuchi, J Silve. The heavy chain of human B-cell alloantigen HLA-DS has a variable N-terminal region and a constant immunoglobulin-like region. Nature. vol 305. issue 5937. 1983-12-17. PMID:6415485. |
we have now isolated a cdna clone from a dr7 cell line that contains the entire coding sequence for the ds alpha subunit and have compared its predicted amino acid sequence with that previously deduced from a ds alpha cdna clone isolated from a dr4,w6 cell line. |
1983-12-17 |
2023-08-12 |
human |
| R W Karr, C C Kannapell, R J Zangara, S M Goyert, J Silver, B D Schwart. An HLA-DR5 homozygous cell line expresses two DS (I-A-like) molecules. The Journal of experimental medicine. vol 158. issue 4. 1983-11-23. PMID:6604786. |
these two ds molecules are formed by the association of a single ds alpha chain with either of two ds beta chains. |
1983-11-23 |
2023-08-12 |
Not clear |
| R Petryshyn, D H Levin, I M Londo. Regulation of double-stranded RNA-activated eukaryotic initiation factor 2 alpha kinase by type 2 protein phosphatase in reticulocyte lysates. Proceedings of the National Academy of Sciences of the United States of America. vol 79. issue 21. 1983-01-27. PMID:6292906. |
protein synthesis initiation in reticulocyte lysates is inhibited by low concentrations (1-20 ng/ml) of double-stranded rna (ds rna) due to the activation of a ds rna-dependent camp-independent protein kinase (ds i) that phosphorylates the alpha subunit of the eukaryotic initiation factor eif-2. |
1983-01-27 |
2023-08-12 |
Not clear |
| S M Goyert, J E Shively, J Silve. Biochemical characterization of a second family of human Ia molecules, HLA-DS, equivalent to murine I-A subregion molecules. The Journal of experimental medicine. vol 156. issue 2. 1982-09-17. PMID:6808075. |
the human hla-ds molecules consist of two polypeptide chains, ds alpha (37,000 mol wt) and ds beta (29,000 mol wt), with 73% amino acid sequence identity to the murine i-a molecules. |
1982-09-17 |
2023-08-12 |
mouse |
| H Hasegawa, H Nagata, M Yamauchi, T Murakoshi, Y Oguma, H Takei, T Seya, M Mura. Role of dextran sulfate in urokinase therapy and evaluation of the effects by estimation of plasmin inhibitor, fibrinogenolytic degradation products, and fibrinolytic degradation products. Japanese heart journal. vol 23. issue 3. 1982-09-10. PMID:6178853. |
however, no marked difference in alpha 2-pi and at-iii existed both just after and at 24 hours after uk treatment in patients receiving uk (240,000 units) with both heparin and ds and those receiving uk (480,000 units) with heparin. |
1982-09-10 |
2023-08-12 |
Not clear |
| H Hasegawa, H Nagata, M Yamauchi, T Murakoshi, Y Oguma, H Takei, T Seya, M Mura. Role of dextran sulfate in urokinase therapy and evaluation of the effects by estimation of plasmin inhibitor, fibrinogenolytic degradation products, and fibrinolytic degradation products. Japanese heart journal. vol 23. issue 3. 1982-09-10. PMID:6178853. |
for these reasons, effective uk treatment appears to require combination with ds and several treatment days under the condition with a decrease of alpha 2-pi (50%) and fibrinogenolysis with fibrinolysis, which are followed by administrations of uk. |
1982-09-10 |
2023-08-12 |
Not clear |
| P H Jongbloet, R R Frants, A J Hamer. Parental alpha 1-antitrypsin (PI) types and meiotic nondisjunction in the aetiology of Down syndrome. Clinical genetics. vol 20. issue 4. 1982-05-21. PMID:6460570. |
assessment of the alpha 1-antitrypsin/alpha 1-protease inhibitor (pi) types in these ds children revealed a significantly higher value of non-m pi variants (p less than 0.05). |
1982-05-21 |
2023-08-12 |
Not clear |
| C Baglioni, M A Minks, E De Clerc. Structural requirements of polynucleotides for the activation of (2' - 5')An polymerase and protein kinase. Nucleic acids research. vol 9. issue 19. 1982-02-12. PMID:6273790. |
two enzymatic pathways are involved in the inhibitory effects of double-stranded (ds)rna on protein synthesis in cell extracts derived from interferon-treated human fibroblasts or hela cells, an oligonucleotide polymerase that synthesizes (2'-5')an from atp and a protein kinase that phosphorylates the alpha subunit of initiation factor eif-2 as well as a polypeptide of mr = 72,000. |
1982-02-12 |
2023-08-12 |
human |
| H O Walthe. On a transcendental equation in the stability analysis of a population growth model. Journal of mathematical biology. vol 3. issue 2. 1977-05-20. PMID:1022830. |
these eigenvalues are the complex solutions gamma of the equation gamma + alpha integral of 0-1exp[gamma a] ds (a) = 0 with alpha greater than 0 and s increasing, s(-1) = 0, s(0) = 1. |
1977-05-20 |
2023-08-11 |
Not clear |