| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S A Welner, P Laplante, J A St Pierre, R Alons. Excitatory and inhibitory amino acids in the cerebral cortex of nucleus basalis magnocellularis lesioned rats. Neuroscience letters. vol 172. issue 1-2. 1994-10-11. PMID:8084544. |
with increasing evidence suggesting the involvement of amino acid transmitters in learning and memory processes, it is of interest to also evaluate possible changes in the levels of amino acid transmitters in the cortex of nucleus basalis magnocellularis-lesioned rats. |
1994-10-11 |
2023-08-12 |
rat |
| A Kharlamov, I Zivkovic, A Polo, D M Armstrong, E Costa, A Guidott. LIGA20, a lyso derivative of ganglioside GM1, given orally after cortical thrombosis reduces infarct size and associated cognition deficit. Proceedings of the National Academy of Sciences of the United States of America. vol 91. issue 14. 1994-08-01. PMID:8022776. |
a bilateral photochemically induced thrombotic lesion of rat sensorimotor cortex (approximately 3 mm in diameter and 25 mm3 in volume) is associated with a persistent cognition (learning and memory) deficit, which was evaluated with water maze tasks. |
1994-08-01 |
2023-08-12 |
rat |
| T Halonen, J Sivenius, R Miettinen, M Halmekytö, R Kauppinen, R Sinervirta, L Alakuijala, L Alhonen, E MacDonald, J Jänn. Elevated seizure threshold and impaired spatial learning in transgenic mice with putrescine overproduction in the brain. The European journal of neuroscience. vol 5. issue 9. 1994-02-15. PMID:8281326. |
we report that the transgenic mice with grossly elevated putrescine in all brain regions analysed (cortex, striatum, hippocampus and cerebellum) showed a significantly elevated seizure threshold to chemical and electrical stimuli, and impaired performance in spatial learning and memory tests. |
1994-02-15 |
2023-08-12 |
mouse |
| L E Jarrar. On the role of the hippocampus in learning and memory in the rat. Behavioral and neural biology. vol 60. issue 1. 1993-11-17. PMID:8216164. |
the limited data that are available using more selective lesions of related hippocampal formation structures (entorhinal cortex, subiculum) suggest that these structures also make important contributions to learning and memory, and that some of these contributions may be different from those made by the hippocampus. |
1993-11-17 |
2023-08-12 |
rat |
| R Miettinen, J Sirviö, P Riekkinen, M P Laakso, M Riekkinen, P Riekkine. Neocortical, hippocampal and septal parvalbumin- and somatostatin-containing neurons in young and aged rats: correlation with passive avoidance and water maze performance. Neuroscience. vol 53. issue 2. 1993-06-11. PMID:8098509. |
we propose that impaired functioning of the entorhinal cortex parvalbumin-containing inhibitory neurons may, to some extent, be responsible for the learning and memory defects found in aged rats. |
1993-06-11 |
2023-08-12 |
rat |
| G A Carpenter, S Grossber. Normal and amnesic learning, recognition and memory by a neural model of cortico-hippocampal interactions. Trends in neurosciences. vol 16. issue 4. 1993-05-11. PMID:7682344. |
in this article, gail carpenter and stephen grossberg describe one such class of model (adaptive resonance theory, art) and discuss how its structure and function might relate to known neurological learning and memory processes, such as how infero-temporal cortex can recognize both specialized and abstract information, and how medial temporal amnesia might be caused by lesions in the hippocampal formation. |
1993-05-11 |
2023-08-12 |
human |
| A C Cuello, D Maysinger, L Garofal. Trophic factor effects on cholinergic innervation in the cerebral cortex of the adult rat brain. Molecular neurobiology. vol 6. issue 4. 1993-03-18. PMID:1285934. |
the cholinergic pathway ascending from the nucleus basalis magnocellularis (nbm) to the cortex has been implicated in several important higher brain functions such as learning and memory. |
1993-03-18 |
2023-08-11 |
rat |
| S Uchida, I Fukuchi, S Kato, M Nakahiro, H Yoshid. Disturbance of learning and memory by the alkylation of muscarinic acetylcholine receptors by propylbenzilylcholine mustard. Gerontology. vol 37 Suppl 1. 1991-12-17. PMID:1937064. |
the effects of blockade of muscarinic acetylcholine receptors (machr) in rat cerebral cortex on learning and memory were studied by the use of passive and active avoidance tests. |
1991-12-17 |
2023-08-11 |
rat |
| Iu V Burov, T N Robakidze, L V Kadysheva, S A Sukhanov. [Experimental study of the effects of amiridin and tacrine on learning and memory]. Biulleten' eksperimental'noi biologii i meditsiny. vol 111. issue 6. 1991-10-18. PMID:1893185. |
the authors studied the influence of amiridin and tacrine on learning and memory in mice and rat by passive avoidance conditioning test at norm and under scopolamine induced amnesia as well as of their effect on acetylcholine esterase (ache) activity in brain cortex homogenates. |
1991-10-18 |
2023-08-11 |
mouse |
| C L Wellman, D R Sengelau. Cortical neuroanatomical correlates of behavioral deficits produced by lesion of the basal forebrain in rats. Behavioral and neural biology. vol 56. issue 1. 1991-09-12. PMID:1867622. |
the cortical morphological changes observed in the present study following basal forebrain lesion provide further evidence for the importance of ascending cholinergic inputs to the cortex and their role in learning and memory. |
1991-09-12 |
2023-08-11 |
rat |
| T Otto, F Schottler, U Staubli, H Eichenbaum, G Lync. Hippocampus and olfactory discrimination learning: effects of entorhinal cortex lesions on olfactory learning and memory in a successive-cue, go-no-go task. Behavioral neuroscience. vol 105. issue 1. 1991-06-07. PMID:2025384. |
hippocampus and olfactory discrimination learning: effects of entorhinal cortex lesions on olfactory learning and memory in a successive-cue, go-no-go task. |
1991-06-07 |
2023-08-11 |
rat |
| T Otto, F Schottler, U Staubli, H Eichenbaum, G Lync. Hippocampus and olfactory discrimination learning: effects of entorhinal cortex lesions on olfactory learning and memory in a successive-cue, go-no-go task. Behavioral neuroscience. vol 105. issue 1. 1991-06-07. PMID:2025384. |
three experiments assessed the effect of entorhinal cortex lesions on olfactory learning and memory using a successive-cue olfactory discrimination paradigm. |
1991-06-07 |
2023-08-11 |
rat |
| J T Greenamyre, A B Youn. Excitatory amino acids and Alzheimer's disease. Neurobiology of aging. vol 10. issue 5. 1989-12-18. PMID:2554168. |
excitatory amino acids (eaa) such as glutamate and aspartate are major transmitters of the cerebral cortex and hippocampus, and eaa mechanisms appear to play a role in learning and memory. |
1989-12-18 |
2023-08-11 |
Not clear |
| A Toumane, T Durkin, A Marighetto, D Galey, R Jaffar. Differential hippocampal and cortical cholinergic activation during the acquisition, retention, reversal and extinction of a spatial discrimination in an 8-arm radial maze by mice. Behavioural brain research. vol 30. issue 3. 1988-12-06. PMID:3178994. |
possible differentiation of the intervention of cholinergic septohippocampal and magnocellular forebrain (nbm) projections to cortex during learning and memory processes has been investigated directly using mice. |
1988-12-06 |
2023-08-11 |
mouse |
| J T Greenamyre, W F Maragos, R L Albin, J B Penney, A B Youn. Glutamate transmission and toxicity in Alzheimer's disease. Progress in neuro-psychopharmacology & biological psychiatry. vol 12. issue 4. 1988-09-21. PMID:2900537. |
glutamate is the major excitatory transmitter of the cerebral cortex and hippocampus and it appears to have an important role in learning and memory. |
1988-09-21 |
2023-08-11 |
Not clear |
| R Metherate, N Tremblay, R W Dyke. Transient and prolonged effects of acetylcholine on responsiveness of cat somatosensory cortical neurons. Journal of neurophysiology. vol 59. issue 4. 1988-06-27. PMID:2897435. |
this mechanism to alter neuronal responsiveness has many of the characteristics necessary to account for the reorganization observed in somatosensory cortex following alterations in its afferent drive and may be related to some forms of learning and memory. |
1988-06-27 |
2023-08-11 |
cat |
| M W Decke. The effects of aging on hippocampal and cortical projections of the forebrain cholinergic system. Brain research. vol 434. issue 4. 1988-02-17. PMID:3319050. |
it has been proposed that disruption of cholinergic input to the hippocampus and cortex contributes to the learning and memory deficits associated with aging. |
1988-02-17 |
2023-08-11 |
Not clear |
| M W Decke. The effects of aging on hippocampal and cortical projections of the forebrain cholinergic system. Brain research. vol 434. issue 4. 1988-02-17. PMID:3319050. |
thus, investigation of these changes in the dynamic properties of cholinergic input to the hippocampus and cortex during aging may provide clarification of the relationship between cholinergic dysfunction and age-related decline in learning and memory and may also provide a more reasonable rationale for treatment approaches. |
1988-02-17 |
2023-08-11 |
Not clear |
| P J Riekkinen, V Laulumaa, J Sirviö, H Soininen, E L Helkal. Recent progress in the research of Alzheimer's disease. Medical biology. vol 65. issue 2-3. 1987-11-19. PMID:3309490. |
the hippocampus and entorhinal cortex seem to play an important role in learning and memory. |
1987-11-19 |
2023-08-11 |
Not clear |
| I Fukuchi, S Kato, M Nakahiro, S Uchida, R Ishida, H Yoshid. Blockade of cholinergic receptors by an irreversible antagonist, propylbenzilylcholine mustard (PrBCM), in the rat cerebral cortex causes deficits in passive avoidance learning. Brain research. vol 400. issue 1. 1987-03-30. PMID:3028567. |
studies were made on the effects of blockade of muscarinic acetylcholine (mach) receptors in the rat cerebral cortex on learning and memory assessed by performance of a step-through passive avoidance task. |
1987-03-30 |
2023-08-11 |
rat |