| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Keith K Murai, Louis N Nguyen, Mitchell Koolpe, Rebecca McLennan, Catherine E Krull, Elena B Pasqual. Targeting the EphA4 receptor in the nervous system with biologically active peptides. Molecular and cellular neurosciences. vol 24. issue 4. 2004-02-27. PMID:14697664. |
in the adult, epha4 is enriched in the hippocampus and cortex, two brain structures critical for learning and memory. |
2004-02-27 |
2023-08-12 |
chicken |
| C C Wrenn, L K Marriott, J W Kinney, A Holmes, G L Wenk, J N Crawle. Galanin peptide levels in hippocampus and cortex of galanin-overexpressing transgenic mice evaluated for cognitive performance. Neuropeptides. vol 36. issue 6. 2004-02-24. PMID:12507436. |
the present study employed radioimmunoassay to quantitate the level of galanin peptide overexpression in two brain regions relevant to learning and memory, the hippocampus and cerebral cortex. |
2004-02-24 |
2023-08-12 |
mouse |
| Abdallah Hadj Tahar, Pierre J Blanchet, Julien Doyo. Motor-learning impairment by amantadine in healthy volunteers. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 1. 2004-02-17. PMID:14532914. |
nmda receptor antagonists impair learning and memory in animal models, presumably by inhibiting long-term potentiation in the motor cortex. |
2004-02-17 |
2023-08-12 |
human |
| Anna Josephson, Alexandra Trifunovski, Camilla Schéele, Johan Widenfalk, Claes Wahlestedt, Stefan Brené, Lars Olson, Christian Spenge. Activity-induced and developmental downregulation of the Nogo receptor. Cell and tissue research. vol 311. issue 3. 2004-02-11. PMID:12658441. |
strong, rapid and transient downregulation of ngr mrna in response to kainic acid and after wheel running in cortex and hippocampus suggests a role for ngr and nogo-a in plasticity, learning and memory. |
2004-02-11 |
2023-08-12 |
rat |
| Bombi Lee, YoungKook Choi, Hocheol Kim, Sun Yeou Kim, Dae-Hyun Hahm, Hye-Jung Lee, Insop Shi. Protective effects of methanol extract of Acori graminei rhizoma and Uncariae Ramulus et Uncus on ischemia-induced neuronal death and cognitive impairments in the rat. Life sciences. vol 74. issue 4. 2004-01-29. PMID:14609722. |
in order to investigate whether agr and ure influenced cerebral ischemia-induced neuronal and cognitive impairments, we examined the effect of agr and ure on ischemia-induced cell death in the striatum, cortex and hippocampus, and on the impaired learning and memory in the morris water maze and radial eight-arm maze in rats. |
2004-01-29 |
2023-08-12 |
rat |
| Z Liao, Z Qi, M Sun, D Yang, J Yu. [The influences of human apolipoprotein E mutants on the learning and memory of cerebral cortex in transgenic mice]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. vol 22. issue 4. 2004-01-06. PMID:12903448. |
[the influences of human apolipoprotein e mutants on the learning and memory of cerebral cortex in transgenic mice]. |
2004-01-06 |
2023-08-12 |
mouse |
| Tatjana A Ishunina, Joop J van Heerikhuize, Rivka Ravid, Dick F Swaa. Estrogen receptors and metabolic activity in the human tuberomamillary nucleus: changes in relation to sex, aging and Alzheimer's disease. Brain research. vol 988. issue 1-2. 2003-12-10. PMID:14519529. |
the human tuberomamillary nucleus (tmn), that is the sole source of histamine in the brain, is involved in arousal, learning and memory and is impaired in alzheimer's disease (ad) as shown by the presence of cytoskeletal alterations, a reduction in the number of large neurons, a diminished neuronal metabolic activity and decreased histamine levels in the hypothalamus and cortex. |
2003-12-10 |
2023-08-12 |
human |
| R Bartesaghi, M Raffi, S Sever. Effects of early isolation on layer II neurons in the entorhinal cortex of the guinea pig. Neuroscience. vol 120. issue 3. 2003-12-04. PMID:12895512. |
the presence of widespread effects of isolation in the entorhinal cortex and numerous hippocampal structures suggests that the outcome of early isolation might be a change in learning and memory functions requiring the hippocampal region. |
2003-12-04 |
2023-08-12 |
Not clear |
| D Yaniv, R M Vouimba, D M Diamond, G Richter-Levi. Simultaneous induction of long-term potentiation in the hippocampus and the amygdala by entorhinal cortex activation: mechanistic and temporal profiles. Neuroscience. vol 120. issue 4. 2003-11-10. PMID:12927217. |
the medial temporal lobe, including the entorhinal cortex, the amygdala and the hippocampus, has an important role in learning and memory, and its circuits exhibit synaptic plasticity (long-term potentiation [ltp]). |
2003-11-10 |
2023-08-12 |
rat |
| Koji Onodera, Nao-Omi Omoi, Koji Fukui, Takahiro Hayasaka, Tadashi Shinkai, Shozo Suzuki, Kouichi Abe, Shiro Uran. Oxidative damage of rat cerebral cortex and hippocampus, and changes in antioxidative defense systems caused by hyperoxia. Free radical research. vol 37. issue 4. 2003-10-10. PMID:12747730. |
in order to elucidate the oxidative damage in rat brain caused by oxidative stress, regional changes in the levels of lipid peroxidation products and antioxidative defense systems in cerebral cortex and hippocampus, and in their synapses, which modulate learning and memory functions in the brain, were studied. |
2003-10-10 |
2023-08-12 |
rat |
| J C López, J P Vargas, Y Gómez, C Sala. Spatial and non-spatial learning in turtles: the role of medial cortex. Behavioural brain research. vol 143. issue 2. 2003-10-07. PMID:12900038. |
in reptiles, a great deal of anatomical evidence indicates that the medial cortex (mc) could be homologous to the hippocampus of mammals and birds; however, few studies have examined the functional role of this structure in relation to learning and memory processes. |
2003-10-07 |
2023-08-12 |
Not clear |
| Kevin P Kaut, Michael D Bunsey, David C Ricci. Olfactory learning and memory impairments following lesions to the hippocampus and perirhinal-entorhinal cortex. Behavioral neuroscience. vol 117. issue 2. 2003-06-04. PMID:12708527. |
olfactory learning and memory impairments following lesions to the hippocampus and perirhinal-entorhinal cortex. |
2003-06-04 |
2023-08-12 |
Not clear |
| J C López, Y Gómez, J P Vargas, C Sala. Spatial reversal learning deficit after medial cortex lesion in turtles. Neuroscience letters. vol 341. issue 3. 2003-05-21. PMID:12697282. |
these results suggest that turtles possess different spatial learning and memory systems in close parallel to those described in other vertebrates, and that medial cortex plays a crucial role in complex place learning. |
2003-05-21 |
2023-08-12 |
Not clear |
| Seralynne D Vann, L A Kristina Wilton, Janice L Muir, John P Aggleto. Testing the importance of the caudal retrosplenial cortex for spatial memory in rats. Behavioural brain research. vol 140. issue 1-2. 2003-04-28. PMID:12644284. |
although there is evidence to suggest that the retrosplenial cortex is involved in spatial learning and memory, many lesion studies have left the more caudal part of this region intact so leaving its role untested. |
2003-04-28 |
2023-08-12 |
rat |
| R Spiege. [Rivastigmine: a review of its clinical effectiveness]. Revista de neurologia. vol 35. issue 9. 2003-04-01. PMID:12436385. |
frontotemporal dementia, dementia in parkinson s disease and vascular dementia [vad]), can be attributed to the loss of acetylcholine and cholinergic neurons in areas of the brain that are central to learning and memory, to execution functions and to behavioural and emotional responses, such as the cerebral cortex, the hippocampus and the limbic regions. |
2003-04-01 |
2023-08-12 |
Not clear |
| Eric J Nestle. Common molecular and cellular substrates of addiction and memory. Neurobiology of learning and memory. vol 78. issue 3. 2003-03-21. PMID:12559841. |
complex circuits involving the hippocampus, cerebral cortex, ventral and dorsal striatum, and amygdala are implicated both in addiction and in learning and memory. |
2003-03-21 |
2023-08-12 |
Not clear |
| Satoshi Takeo, Tomoko Fukatsu, Keiko Miyake-Takagi, Norio Takagi, Makiko Niimura, Akira Nagakura, Tsuyoshi Ando, Kouichi Tanonak. Persistent effects of delayed treatment with nefiracetam on the water maze task in rats with sustained cerebral ischemia. The Journal of pharmacology and experimental therapeutics. vol 304. issue 2. 2003-03-03. PMID:12538802. |
the functional damage to learning and memory was associated with decreases in the membranous adenylyl cyclase i and cytosolic protein kinase a (pka) catalytic subunit and regulatory subunit proteins in the right hippocampus and cerebral cortex. |
2003-03-03 |
2023-08-12 |
rat |
| Kevin A Corcoran, Ye Lu, R Scott Turner, Stephen Mare. Overexpression of hAPPswe impairs rewarded alternation and contextual fear conditioning in a transgenic mouse model of Alzheimer's disease. Learning & memory (Cold Spring Harbor, N.Y.). vol 9. issue 5. 2002-11-15. PMID:12359834. |
hence, learning and memory deficits in old tg2576 mice are limited to hippocampus-dependent tasks, despite widespread amyloid deposition in cortex, hippocampus, and amygdala. |
2002-11-15 |
2023-08-12 |
mouse |
| Noritaka Ichinohe, Kathleen S Rocklan. Parvalbumin positive dendrites co-localize with apical dendritic bundles in rat retrosplenial cortex. Neuroreport. vol 13. issue 6. 2002-06-26. PMID:11997682. |
the granular retrosplenial cortex in rats, involved in learning and memory, has a highly modular organization in layer 1. |
2002-06-26 |
2023-08-12 |
rat |
| H C Barefoot, H F Baker, R M Ridle. Crossed unilateral lesions of temporal lobe structures and cholinergic cell bodies impair visual conditional and object discrimination learning in monkeys. The European journal of neuroscience. vol 15. issue 3. 2002-05-07. PMID:11876778. |
this argues that it is the cholinergic projection to the inferotemporal cortex, rather than to the rest of the cortex, which contributes to visual discrimination learning and memory. |
2002-05-07 |
2023-08-12 |
monkey |