| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tim Vanmierlo, Kris Rutten, Leonie C van Vark-van der Zee, Silvia Friedrichs, Vincent W Bloks, Arjan Blokland, Frans C Ramaekers, Eric Sijbrands, Harry Steinbusch, Jos Prickaerts, Folkert Kuipers, Dieter Lütjohann, Monique Mulde. Cerebral accumulation of dietary derivable plant sterols does not interfere with memory and anxiety related behavior in Abcg5-/- mice. Plant foods for human nutrition (Dordrecht, Netherlands). vol 66. issue 2. 2011-10-31. PMID:21431910. |
plant sterol accumulation resulted in decreased levels of desmosterol (p<0.01) and 24(s)-hydroxycholesterol (p<0.01) in the hippocampus, the brain region important for learning and memory functions, and increased lanosterol levels (p<0.01) in the cortex. |
2011-10-31 |
2023-08-12 |
mouse |
| Xiao-Ping Chen, Xiang Wang, Jing-Yin Don. Different reaction patterns of dopamine content to prenatal exposure to chlorpyrifos in different periods. Journal of applied toxicology : JAT. vol 31. issue 4. 2011-09-16. PMID:21089160. |
these results suggest that the two key brain regions involved in learning and memory, the cerebral cortex and hippocampus, react differently to cpf exposure in different prenatal periods. |
2011-09-16 |
2023-08-12 |
Not clear |
| Xiao-Rui Cheng, Yong Yang, Wen-Xia Zhou, Yong-Xiang Zhan. Expression of VGLUTs contributes to degeneration and acquisition of learning and memory. Neurobiology of learning and memory. vol 95. issue 3. 2011-08-03. PMID:21295146. |
our results demonstrate that, in the cerebral cortex, protein expression of vglut1, vglut2, vglut3 and syp was decreased in samp8 with age and increased in km mice, which displayed an enhanced capacity for learning and memory. |
2011-08-03 |
2023-08-12 |
mouse |
| Kathy R Magnusson, Brenna L Brim, Siba R Da. Selective Vulnerabilities of N-methyl-D-aspartate (NMDA) Receptors During Brain Aging. Frontiers in aging neuroscience. vol 2. 2011-07-14. PMID:20552049. |
n-methyl-d-aspartate (nmda) receptors are present in high density within the cerebral cortex and hippocampus and play an important role in learning and memory. |
2011-07-14 |
2023-08-12 |
Not clear |
| Yong-Lin Jia, Li-Jun Jing, Jin-Yi Li, Jing-Jing Lu, Rui Han, Shu-Yang Wang, Tao Peng, Yan-Jie Ji. Expression and significance of DSCAM in the cerebral cortex of APP transgenic mice. Neuroscience letters. vol 491. issue 2. 2011-07-05. PMID:21241773. |
we propose that overexpression of dscam in the cerebral cortex might play an important role in the learning and memory defects of app transgenic mice. |
2011-07-05 |
2023-08-12 |
mouse |
| Teresa A Milner, Louisa I Thompson, Gang Wang, Justin A Kievits, Eugene Martin, Ping Zhou, Bruce S McEwen, Donald W Pfaff, Elizabeth M Water. Distribution of estrogen receptor β containing cells in the brains of bacterial artificial chromosome transgenic mice. Brain research. vol 1351. 2011-05-17. PMID:20599828. |
in particular, erbeta-egfp cells were found in autonomic brain regions (i.e., hypothalamic paraventricular nucleus, rostral ventrolateral medulla and nucleus of the solitary tract), in regions associated with anxiety and stress behaviors (i.e., bed nucleus of the stria terminalis, amygdala, periaqueductal gray, raphe and parabrachial nuclei) and in regions involved in learning and memory processes (i.e., basal forebrain, cerebral cortex and hippocampus). |
2011-05-17 |
2023-08-12 |
mouse |
| Dong Liu, Michael Pitta, Jong-Hwan Lee, Balmiki Ray, Debomoy K Lahiri, Katsutoshi Furukawa, Mohamed Mughal, Haiyang Jiang, Julissa Villarreal, Roy G Cutler, Nigel H Greig, Mark P Mattso. The KATP channel activator diazoxide ameliorates amyloid-β and tau pathologies and improves memory in the 3xTgAD mouse model of Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 22. issue 2. 2011-03-09. PMID:20847430. |
3xtgad mice treated with diazoxide for 8 months exhibited improved performance in a learning and memory test, reduced levels of anxiety, decreased accumulation of aβ oligomers and hyperphosphorylated tau in the cortex and hippocampus, and increased cerebral blood flow. |
2011-03-09 |
2023-08-12 |
mouse |
| Reihaneh Hoveida, Hojjatallah Alaei, Shahrbanoo Oryan, Kazem Parivar, Parham Reis. Treadmill running improves spatial memory in an animal model of Alzheimer's disease. Behavioural brain research. vol 216. issue 1. 2011-02-18. PMID:20709113. |
alzheimer's disease (ad) is a progressive neurodegenerative disease that is characterized by a decline in cognitive function and severe neuronal loss in the cerebral cortex and certain subcortical regions of the brain including nucleus basalis magnocellularis (nbm) that play an important role in learning and memory. |
2011-02-18 |
2023-08-12 |
rat |
| Yi Wang, Yi Hou, Jing Dong, Hongde Xu, Jian Gong, Jie Che. Developmental iodine deficiency and hypothyroidism reduce phosphorylation of calcium/calmodulin-dependent kinase II in the rat entorhinal cortex. Biological trace element research. vol 137. issue 3. 2011-01-31. PMID:20054663. |
though the entorhinal cortex (ec) is an important functional structure within the neuronal network responsible for learning and memory, little is known about the effect of hypothyroidism on phosphorylation of camkii in the ec. |
2011-01-31 |
2023-08-12 |
rat |
| P A McCoy, L L McMaho. Sympathetic sprouting in visual cortex stimulated by cholinergic denervation rescues expression of two forms of long-term depression at layer 2/3 synapses. Neuroscience. vol 168. issue 3. 2010-09-21. PMID:20412838. |
cholinergic innervation of hippocampus and cortex is required for some forms of learning and memory. |
2010-09-21 |
2023-08-12 |
Not clear |
| N L M Cappaert, F H Lopes da Silva, W J Wadma. Spatio-temporal dynamics of theta oscillations in hippocampal-entorhinal slices. Hippocampus. vol 19. issue 11. 2010-04-27. PMID:19338021. |
theta oscillations (4-12 hz) are associated with learning and memory and are found in the hippocampus and the entorhinal cortex (ec). |
2010-04-27 |
2023-08-12 |
Not clear |
| Shigeki Yuas. [Somatotopy in the emotional expression by the amygdala]. Brain and nerve = Shinkei kenkyu no shinpo. vol 61. issue 12. 2010-02-25. PMID:20034306. |
this output to the cortex is directed to the prefrontal cortex and the medial temporal lobe, a memory system, and modulates the higher cortical functions as well as the learning and memory. |
2010-02-25 |
2023-08-12 |
monkey |
| J D Adam. Chemical interactions with pyramidal neurons in layer 5 of the cerebral cortex: control of pain and anxiety. Current medicinal chemistry. vol 16. issue 27. 2009-12-16. PMID:19799545. |
pyramidal neurons in layer 5 of the cerebral cortex are involved in learning and memory and have complex connections with other neurons through a very large array of dendrites. |
2009-12-16 |
2023-08-12 |
Not clear |
| Evelin L Schaeffer, Barbara A Novaes, Emanuelle R da Silva, Heni D Skaf, Alvaro G Mendes-Net. Strategies to promote differentiation of newborn neurons into mature functional cells in Alzheimer brain. Progress in neuro-psychopharmacology & biological psychiatry. vol 33. issue 7. 2009-11-17. PMID:19596396. |
alzheimer disease (ad) is characterized by neuron loss in the hippocampus (dg and ca1 field), entorhinal cortex, and association neocortex, which underlies the learning and memory deficits. |
2009-11-17 |
2023-08-12 |
Not clear |
| Vitaly Feldman, Leslie G Valian. Experience-induced neural circuits that achieve high capacity. Neural computation. vol 21. issue 10. 2009-11-13. PMID:19635015. |
our underlying theory is apparently the only biologically plausible systems-level theory of learning and memory in cortex for which such a demonstration has been performed, and we argue that no general theory of information processing in the brain can be considered viable without such a demonstration. |
2009-11-13 |
2023-08-12 |
Not clear |
| R Liu, M Gao, G-F Qiang, T-T Zhang, X Lan, J Ying, G-H D. The anti-amnesic effects of luteolin against amyloid beta(25-35) peptide-induced toxicity in mice involve the protection of neurovascular unit. Neuroscience. vol 162. issue 4. 2009-11-10. PMID:19442706. |
the learning and memory impairments, ultrastructural changes of cerebral cortex, cerebrovascular dysfunction and neuronal changes were detected after oral administration of luteolin continuously for 8 days. |
2009-11-10 |
2023-08-12 |
mouse |
| R Liu, M Gao, G-F Qiang, T-T Zhang, X Lan, J Ying, G-H D. The anti-amnesic effects of luteolin against amyloid beta(25-35) peptide-induced toxicity in mice involve the protection of neurovascular unit. Neuroscience. vol 162. issue 4. 2009-11-10. PMID:19442706. |
our results demonstrate that oral administration of luteolin for 8 days for those abeta(25-35)-induced amnesic mice conferred robust neurovascular protection in abeta(25-35)-induced amnesia, involving the improvement of the spatial learning and memory capabilities, the modulation of microvascular function, the increase of regional cerebral blood flow values, the clearance of reactive oxygen species, the improvement of cholinergic neuronal system, and the increase of brain-derived neurotrophic factor level and its receptor tyrosine kinase b expression in cerebral cortex. |
2009-11-10 |
2023-08-12 |
mouse |
| R F Thompson, J E Steinmet. The role of the cerebellum in classical conditioning of discrete behavioral responses. Neuroscience. vol 162. issue 3. 2009-10-19. PMID:19409234. |
we argue that the cortex plays a key role in normal acquisition and adaptive timing of the conditioned response, under certain circumstances, but it remains unclear exactly what features of conditioning are being encoded in the cerebellar cortex in this basic form of associative learning and memory. |
2009-10-19 |
2023-08-12 |
Not clear |
| Pan-Yue Deng, Zhaoyang Xiao, Chuanxiu Yang, Lalida Rojanathammanee, Laurel Grisanti, John Watt, Jonathan D Geiger, Rugao Liu, James E Porter, Saobo Le. GABA(B) receptor activation inhibits neuronal excitability and spatial learning in the entorhinal cortex by activating TREK-2 K+ channels. Neuron. vol 63. issue 2. 2009-09-30. PMID:19640481. |
the entorhinal cortex (ec) is regarded as the gateway to the hippocampus and thus is essential for learning and memory. |
2009-09-30 |
2023-08-12 |
Not clear |
| Wei-wei Ma, Li Xiang, Huan-Ling Yu, Lin-Hong Yuan, Ai-Min Guo, Yi-Xiu Xiao, Li Li, Rong Xia. Neuroprotection of soyabean isoflavone co-administration with folic acid against beta-amyloid 1-40-induced neurotoxicity in rats. The British journal of nutrition. vol 102. issue 4. 2009-09-11. PMID:19534845. |
in the present study, the learning and memory ability of rats and the amount of amyloid-positive neurons in the cerebral cortex and hippocampal ca1 area were measured. |
2009-09-11 |
2023-08-12 |
rat |