| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Keigo Kohara, Michele Pignatelli, Alexander J Rivest, Hae-Yoon Jung, Takashi Kitamura, Junghyup Suh, Dominic Frank, Koichiro Kajikawa, Nathan Mise, Yuichi Obata, Ian R Wickersham, Susumu Tonegaw. Cell type-specific genetic and optogenetic tools reveal hippocampal CA2 circuits. Nature neuroscience. vol 17. issue 2. 2014-03-24. PMID:24336151. |
for several decades, the trisynaptic circuit entorhinal cortex layer ii (ecii)→dentate gyrus→ca3→ca1 and the monosynaptic circuit eciii→ca1 have been considered the primary substrates of the network responsible for learning and memory. |
2014-03-24 |
2023-08-12 |
mouse |
| M R Williams, R Marsh, C D Macdonald, J Jain, R K B Pearce, S R Hirsch, O Ansorge, S M Gentleman, M Maie. Neuropathological changes in the nucleus basalis in schizophrenia. European archives of psychiatry and clinical neuroscience. vol 263. issue 6. 2014-03-21. PMID:23229688. |
the nucleus basalis is a collection of large cholinergic neurons in the basal forebrain receiving information from the midbrain and limbic system, projecting to the cortex and involved with attention, learning and memory, and receives regulation from serotonergic inputs. |
2014-03-21 |
2023-08-12 |
Not clear |
| Max F K Happel, Matthias Deliano, Juliane Handschuh, Frank W Oh. Dopamine-modulated recurrent corticoefferent feedback in primary sensory cortex promotes detection of behaviorally relevant stimuli. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 4. 2014-03-11. PMID:24453315. |
dopaminergic neurotransmission in primary auditory cortex (ai) has been shown to be involved in learning and memory functions. |
2014-03-11 |
2023-08-12 |
Not clear |
| Qin Zhihu. Modulating nitric oxide signaling in the CNS for Alzheimer's disease therapy. Future medicinal chemistry. vol 5. issue 12. 2014-02-19. PMID:23919554. |
nitric oxide (no)/solube gc (sgc)/cgmp signaling is important for modulating synaptic transmission and plasticity in the hippocampus and cerebral cortex, which are critical for learning and memory. |
2014-02-19 |
2023-08-12 |
Not clear |
| Gustavo A Rodriguez, Mark P Burns, Edwin J Weeber, G William Rebec. Young APOE4 targeted replacement mice exhibit poor spatial learning and memory, with reduced dendritic spine density in the medial entorhinal cortex. Learning & memory (Cold Spring Harbor, N.Y.). vol 20. issue 5. 2013-10-29. PMID:23592036. |
young apoe4 targeted replacement mice exhibit poor spatial learning and memory, with reduced dendritic spine density in the medial entorhinal cortex. |
2013-10-29 |
2023-08-12 |
mouse |
| Dany Arsenault, Carl Julien, Chuck T Chen, Richard P Bazinet, Frédéric Calo. Dietary intake of unsaturated fatty acids modulates physiological properties of entorhinal cortex neurons in mice. Journal of neurochemistry. vol 122. issue 2. 2013-08-14. PMID:22551210. |
the enthorinal cortex (ec) neurons connecting to the hippocampus play a critical role in learning and memory. |
2013-08-14 |
2023-08-12 |
mouse |
| Bei Zhao, Bai-Shen Pan, Su-Wen Shen, Xiao Sun, Zheng-Zhou Hou, Riqiang Yan, Feng-Yan Su. Diabetes-induced central neuritic dystrophy and cognitive deficits are associated with the formation of oligomeric reticulon-3 via oxidative stress. The Journal of biological chemistry. vol 288. issue 22. 2013-08-06. PMID:23592790. |
we found that the diabetic rats with an impairment of spatial learning and memory showed the occurrence of rtn3-immunoreactive dystrophic neurites in the cortex. |
2013-08-06 |
2023-08-12 |
rat |
| Theodore J Price, Sourav Ghos. ZIPping to pain relief: the role (or not) of PKMζ in chronic pain. Molecular pain. vol 9. 2013-07-16. PMID:23433248. |
a major theme that has emerged in this area of work is the strong similarity between plasticity involved in learning and memory in cns regions such as cortex and hippocampus with mechanisms underlying chronic pain development and maintenance in the spinal dorsal horn and other cns areas such as anterior cingulate cortex (acc). |
2013-07-16 |
2023-08-12 |
Not clear |
| Daphne Voineskos, Nigel C Rogasch, Tarek K Rajji, Paul B Fitzgerald, Zafiris J Daskalaki. A review of evidence linking disrupted neural plasticity to schizophrenia. Canadian journal of psychiatry. Revue canadienne de psychiatrie. vol 58. issue 2. 2013-07-01. PMID:23442895. |
learning and memory have been hypothesized to occur through modifications of the strength of neural circuits, particularly in the hippocampus and cortex. |
2013-07-01 |
2023-08-12 |
human |
| Charlotte M Wincott, Seonil Kim, Roseann F Titcombe, David S Tukey, Hiwot K Girma, Joseph E Pick, Loren M Devito, Franz Hofmann, Charles Hoeffer, Edward B Zif. Spatial memory deficits and motor coordination facilitation in cGMP-dependent protein kinase type II-deficient mice. Neurobiology of learning and memory. vol 99. 2013-06-17. PMID:23103773. |
since cgkii is expressed in the striatum, amygdala, cerebral cortex, and hippocampus, it has been proposed that mice lacking cgkii may present phenotypic differences compared to their wild-type littermates in emotion-dependent tasks, learning and memory, and drug reward salience. |
2013-06-17 |
2023-08-12 |
mouse |
| Robert Nisticò, Virve Cavallucci, Sonia Piccinin, Simone Macrì, Marco Pignatelli, Bisan Mehdawy, Fabio Blandini, Giovanni Laviola, Davide Lauro, Nicola B Mercuri, Marcello D'Ameli. Insulin receptor β-subunit haploinsufficiency impairs hippocampal late-phase LTP and recognition memory. Neuromolecular medicine. vol 14. issue 4. 2013-05-07. PMID:22661254. |
irs are also abundantly distributed in the cerebral cortex and hippocampus, where they regulate synaptic activity required for learning and memory. |
2013-05-07 |
2023-08-12 |
mouse |
| Miki Miyajima, Takuya Numata, Moemi Minoshima, Masato Tanaka, Ryo Nishimura, Toshiyuki Hosokawa, Masaaki Kurasaki, Takeshi Sait. Deficiency of catecholamine syntheses caused by downregulation of phosphorylation of tyrosine hydroxylase in the cerebral cortex of the senescence-accelerated mouse prone 10 strain with aging. Archives of gerontology and geriatrics. vol 56. issue 1. 2013-05-03. PMID:22738763. |
the present study suggests that the decline of learning and memory abilities of samp10 is caused by a decrease in catecholamine synthesis in the cerebral cortex with aging. |
2013-05-03 |
2023-08-12 |
mouse |
| Oscar U Scremin, Keith M Norman, Margareth Roch, Daniel P Holschneider, A M Erika Scremi. Acetylcholinesterase inhibition interacts with training to reverse spatial learning deficits after cortical impact injury. Journal of neurotrauma. vol 29. issue 15. 2013-04-23. PMID:22738336. |
the present investigation was designed to test the ability of continuous administration, starting at the time of injury, of physostigmine (phy), an acetylcholinesterase (ache) inhibitor that crosses the blood-brain barrier (bbb), to ameliorate the alterations of learning and memory induced by cerebral cortex impact injury in rats under isoflurane anesthesia. |
2013-04-23 |
2023-08-12 |
rat |
| A D Gonzalez, G Wang, E M Waters, K L Gonzales, R C Speth, T A Van Kempen, J Marques-Lopes, C N Young, S D Butler, R L Davisson, C Iadecola, V M Pickel, J P Pierce, T A Milne. Distribution of angiotensin type 1a receptor-containing cells in the brains of bacterial artificial chromosome transgenic mice. Neuroscience. vol 226. 2013-04-22. PMID:22922351. |
in particular, at1ar-egfp cells were in autonomic regions (e.g., hypothalamic paraventricular nucleus, central nucleus of the amygdala, parabrachial nucleus, nuclei of the solitary tract and rostral ventrolateral medulla) and in regions involved in electrolyte and fluid balance (i.e., subfornical organ) and learning and memory (i.e., cerebral cortex and hippocampus). |
2013-04-22 |
2023-08-12 |
mouse |
| Jing Ai, Li-Hua Sun, Hui Che, Rong Zhang, Tian-Zhu Zhang, Wan-Chen Wu, Xiao-Lin Su, Xin Chen, Guang Yang, Kang Li, Ning Wang, Tao Ban, Ya-Nan Bao, Fei Guo, Hui-Fang Niu, Yu-Lan Zhu, Xiu-Ying Zhu, Shi-Guang Zhao, Bao-Feng Yan. MicroRNA-195 protects against dementia induced by chronic brain hypoperfusion via its anti-amyloidogenic effect in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 9. 2013-04-22. PMID:23447608. |
we show here that cbh generated by bilateral common carotid artery occlusion (2vo) significantly decreased the learning and memory ability in rats, as assessed by morris water maze, and upregulated expression of app and bace1 proteins in the hippocampus and cortex of rats, as evaluated by western blot and immunofluorescence. |
2013-04-22 |
2023-08-12 |
rat |
| Rui-Feng Liang, Wei-Qing Li, Xiao-Hui Wang, Hui-Fang Zhang, Hong Wang, Jun-Xia Wang, Yu Zhang, Ming-Tao Wan, Bao-Long Pan, Qiao Ni. Aluminium-maltolate-induced impairment of learning, memory and hippocampal long-term potentiation in rats. Industrial health. vol 50. issue 5. 2013-04-05. PMID:22878356. |
our studies indicate that subchronic al (mal)(3) exposure significantly impaired spatial learning and memory abilities, suppressed the ltp in the ca1 hippocampal area, and elevated al levels in cerebral cortex in a dose-dependent fashion. |
2013-04-05 |
2023-08-12 |
rat |
| Saida Haider, Saima Khaliq, Saiqa Tabassum, Darakhshan J Halee. Role of somatodendritic and postsynaptic 5-HT₁A receptors on learning and memory functions in rats. Neurochemical research. vol 37. issue 10. 2013-02-19. PMID:22814880. |
among the 5-ht receptors subtypes, 5-ht(1a) receptors are of special interest because these receptors are present in the brain areas involved in learning and memory functions such as hippocampus and cortex. |
2013-02-19 |
2023-08-12 |
rat |
| Xiao-Ping Rao, Zhi-Xiang Xu, Fu-Qiang X. [Progress in activity-dependent structural plasticity of neural circuits in cortex]. Dong wu xue yan jiu = Zoological research. vol 33. issue 5. 2013-02-07. PMID:23019036. |
neural circuits of mammalian cerebral cortex have exhibited amazing abilities of structural and functional plasticity in development, learning and memory, neurological and psychiatric diseases. |
2013-02-07 |
2023-08-12 |
Not clear |
| Hui Liu, Junjian Zhang, Ying Yang, Lei Zhang, Xingxing Zen. Decreased cerebral perfusion and oxidative stress result in acute and delayed cognitive impairment. Current neurovascular research. vol 9. issue 3. 2013-01-14. PMID:22621229. |
spatial learning and memory were tested with the morris water maze, and oxidative damage was evaluated by measuring malondialdehyde (mda) levels in both the hippocampus and cortex. |
2013-01-14 |
2023-08-12 |
rat |
| Charlotte K Callaghan, Vincent Hok, Andrea Della-Chiesa, David J Virley, Neil Upton, Shane M O'Mar. Age-related declines in delayed non-match-to-sample performance (DNMS) are reversed by the novel 5HT6 receptor antagonist SB742457. Neuropharmacology. vol 63. issue 5. 2013-01-14. PMID:22766392. |
the serotonin receptor subtype 5ht6 is distributed within cns regions relevant to learning and memory, including the striatum, cortex and hippocampus. |
2013-01-14 |
2023-08-12 |
rat |