| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Amy C Porter, Frank P Bymaster, Neil W DeLapp, Masahisa Yamada, Jürgen Wess, Susan E Hamilton, Neil M Nathanson, Christian C Felde. M1 muscarinic receptor signaling in mouse hippocampus and cortex. Brain research. vol 944. issue 1-2. 2002-10-11. PMID:12106668. |
muscarinic receptor stimulated g(alpha)(q)/11-specific gtp-gamma-35s binding was virtually abolished in both the hippocampus and cortex of m1 receptor knockout (ko) mice. |
2002-10-11 |
2023-08-12 |
mouse |
| Tom Deboer, Adriano Fontana, Irene Toble. Tumor necrosis factor (TNF) ligand and TNF receptor deficiency affects sleep and the sleep EEG. Journal of neurophysiology. vol 88. issue 2. 2002-09-23. PMID:12163535. |
our data suggest that in ligand ko the swa increase is caused by an increase in excitatory input to the cortex, whereas in r1ko this input seems to be almost absent. |
2002-09-23 |
2023-08-12 |
mouse |
| b' Mauro Maccarrone, Olga Valverde, Maria L Barbaccia, Anna Casta\\xc3\\xb1\\xc3\\xa9, Rafael Maldonado, Catherine Ledent, Marc Parmentier, Alessandro Finazzi-Agr\\xc3\\xb. Age-related changes of anandamide metabolism in CB1 cannabinoid receptor knockout mice: correlation with behaviour. The European journal of neuroscience. vol 15. issue 7. 2002-06-21. PMID:11982628.' |
the age dependence of amt and faah activity were investigated in 1- or 4-month-old wt and ko animals, and found to increase with age in ko, but not wt, mice and to be higher in the hippocampus than in the cortex of all animals. |
2002-06-21 |
2023-08-12 |
mouse |
| b' Mauro Maccarrone, Olga Valverde, Maria L Barbaccia, Anna Casta\\xc3\\xb1\\xc3\\xa9, Rafael Maldonado, Catherine Ledent, Marc Parmentier, Alessandro Finazzi-Agr\\xc3\\xb. Age-related changes of anandamide metabolism in CB1 cannabinoid receptor knockout mice: correlation with behaviour. The European journal of neuroscience. vol 15. issue 7. 2002-06-21. PMID:11982628.' |
in the same regions, 2-ag failed to change across groups, while aea was significantly decreased (approximately 30%) in hippocampus, but not in cortex, of old ko mice, when compared with young ko or age-matched wt animals. |
2002-06-21 |
2023-08-12 |
mouse |
| Weilie Zhang, Anthony S Basile, Jesus Gomeza, Laura A Volpicelli, Allan I Levey, Jürgen Wes. Characterization of central inhibitory muscarinic autoreceptors by the use of muscarinic acetylcholine receptor knock-out mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 5. 2002-03-22. PMID:11880500. |
strikingly, release studies with brain slices from m2 and m4 receptor single ko mice indicated that autoinhibition of ach release is mediated primarily by the m2 receptor in hippocampus and cerebral cortex, but predominantly by the m4 receptor in the striatum. |
2002-03-22 |
2023-08-12 |
mouse |
| A M Persico, E Mengual, R Moessner, F S Hall, R S Revay, I Sora, J Arellano, J DeFelipe, J M Gimenez-Amaya, M Conciatori, R Marino, A Baldi, S Cabib, T Pascucci, G R Uhl, D L Murphy, K P Lesch, F Keller, S F Hal. Barrel pattern formation requires serotonin uptake by thalamocortical afferents, and not vesicular monoamine release. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 17. 2001-09-20. PMID:11517274. |
5-htt knock-out (ko) mice reveal a nearly complete absence of 5-ht in the cerebral cortex by immunohistochemistry, and of barrels, both at p7 and adulthood. |
2001-09-20 |
2023-08-12 |
mouse |
| A M Persico, E Mengual, R Moessner, F S Hall, R S Revay, I Sora, J Arellano, J DeFelipe, J M Gimenez-Amaya, M Conciatori, R Marino, A Baldi, S Cabib, T Pascucci, G R Uhl, D L Murphy, K P Lesch, F Keller, S F Hal. Barrel pattern formation requires serotonin uptake by thalamocortical afferents, and not vesicular monoamine release. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 17. 2001-09-20. PMID:11517274. |
vmat2 ko mice, completely lacking activity-dependent vesicular release of monoamines including 5-ht, also show a complete lack of 5-ht in the cortex but display largely normal barrel fields, despite sometimes markedly reduced postnatal growth. |
2001-09-20 |
2023-08-12 |
mouse |
| S Sugiura, R Lahav, J Han, S Y Kou, L R Banner, F de Pablo, P H Patterso. Leukaemia inhibitory factor is required for normal inflammatory responses to injury in the peripheral and central nervous systems in vivo and is chemotactic for macrophages in vitro. The European journal of neuroscience. vol 12. issue 2. 2000-05-25. PMID:10712626. |
similarly, the microglial and astroglial responses to surgical injury of the cortex are significantly slower in lif ko mice compared with wt mice. |
2000-05-25 |
2023-08-12 |
mouse |
| A U Trendelenburg, L Hein, E G Gaiser, K Stark. Occurrence, pharmacology and function of presynaptic alpha2-autoreceptors in alpha2A/D-adrenoceptor-deficient mice. Naunyn-Schmiedeberg's archives of pharmacology. vol 360. issue 5. 2000-02-07. PMID:10598793. |
the occurrence, pharmacological properties and function of alpha2-autoreceptors were studied in hippocampal slices, occipito-parietal cortex slices, segments of heart atria and segments of the vas deferens of wildtype (wt) mice and mice in which the alpha2 a/d-adrenoceptor gene had been disrupted (alpha2 a/d(ko)). |
2000-02-07 |
2023-08-12 |
mouse |