| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ozge Ilhan-Sarac, Esen Karamursel Akpe. Current concepts and techniques in keratoprosthesis. Current opinion in ophthalmology. vol 16. issue 4. 2005-10-11. PMID:16000898. |
diseases affecting the cornea are a major cause of blindness worldwide, second only to cataract in overall importance, with an estimated 10 to 15 million affected people. |
2005-10-11 |
2023-08-12 |
Not clear |
| Thomas G Benede. Gonorrhea and the beginnings of clinical research ethics. Perspectives in biology and medicine. vol 48. issue 1. 2005-05-09. PMID:15681879. |
once these two causes of blindness were tentatively differentiated, attempts to restore vision in an eye that had been blinded by a trachomatous membrane over the cornea by instilling gonorrheal pus began to be practiced. |
2005-05-09 |
2023-08-12 |
human |
| Illona Gillette-Ferguson, Amy G Hise, Helen F McGarry, Joseph Turner, Andrew Esposito, Yan Sun, Eugenia Diaconu, Mark J Taylor, Eric Pearlma. Wolbachia-induced neutrophil activation in a mouse model of ocular onchocerciasis (river blindness). Infection and immunity. vol 72. issue 10. 2004-10-25. PMID:15385467. |
endosymbiotic wolbachia bacteria are abundant in the filarial nematodes that cause onchocerciasis (river blindness), including the larvae (microfilariae) that migrate into the cornea. |
2004-10-25 |
2023-08-12 |
mouse |
| Amy G Hise, Illona Gillette-Ferguson, Eric Pearlma. Immunopathogenesis of Onchocerca volvulus keratitis (river blindness): a novel role for TLR4 and endosymbiotic Wolbachia bacteria. Journal of endotoxin research. vol 9. issue 6. 2004-08-16. PMID:14733727. |
infection with the parasitic nematode onchocerca volvulus is associated with inflammation of the skin and cornea that can lead to blindness. |
2004-08-16 |
2023-08-12 |
mouse |
| R FRIED. [Prevention of blindness in disease of the cornea. II. Favorable response of total leukoma to combined medical and surgical therapy]. Klinische Monatsblatter fur Augenheilkunde und fur augenarztliche Fortbildung. vol 117. issue 5. 2004-02-15. PMID:14804921. |
[prevention of blindness in disease of the cornea. |
2004-02-15 |
2023-08-12 |
Not clear |
| R FRIED. [On the control of blindness caused by disease of the cornea. III. A new treatment of parenchymatous keratitis in congenital syphilis]. Klinische Monatsblatter fur Augenheilkunde und fur augenarztliche Fortbildung. vol 119. issue 1. 2004-02-15. PMID:14889715. |
[on the control of blindness caused by disease of the cornea. |
2004-02-15 |
2023-08-12 |
Not clear |
| D Miles, S Athmanathan, A Thakur, M Willco. A novel apoptotic interaction between HSV-1 and human corneal epithelial cells. Current eye research. vol 26. issue 3-4. 2003-09-22. PMID:12815544. |
herpes simplex virus type 1 (hsv-1) infects the cornea possibly causing blindness. |
2003-09-22 |
2023-08-12 |
human |
| W H SPENCE. Pseudomonas aeruginosa infections of the eye. California medicine. vol 79. issue 6. 2003-05-01. PMID:13106731. |
when introduced into the cornea, however, as in penetration by a foreign body or in contaminated medicines, it acts with extreme virulence, in many cases causing blindness and even necessitating enucleation. |
2003-05-01 |
2023-08-12 |
Not clear |
| Wilhelm Stork, Ilos Ei. Micro displays as intraocular vision aid--design of an optical system. Biomedizinische Technik. Biomedical engineering. vol 47 Suppl 1 Pt 1. 2003-03-06. PMID:12451803. |
all over the world about 10 million people suffer from blindness caused by an opaque, irreversible damaged and inoperable cornea. |
2003-03-06 |
2023-08-12 |
Not clear |
| Jerry Y Niederkor. The role of the innate and adaptive immune responses in Acanthamoeba keratitis. Archivum immunologiae et therapiae experimentalis. vol 50. issue 1. 2002-10-04. PMID:11916309. |
protozoal, viral, bacterial, and helminthic infections of the cornea account for up to 9 million cases of corneal blindness. |
2002-10-04 |
2023-08-12 |
Not clear |
| Ravi B Berger, Nathan M Blackwell, Jonathan H Lass, Eugenia Diaconu, Eric Pearlma. IL-4 and IL-13 regulation of ICAM-1 expression and eosinophil recruitment in Onchocerca volvulus keratitis. Investigative ophthalmology & visual science. vol 43. issue 9. 2002-09-12. PMID:12202520. |
using a mouse model of onchocerca volvulus-mediated keratitis (river blindness), the present study examined the role of the cytokines interleukin (il)-4 and il-13 in regulating recruitment of eosinophils to the cornea through expression of intercellular cell adhesion molecule (icam)-1. |
2002-09-12 |
2023-08-12 |
mouse |
| F B Akinsola, A I Ajaiyeob. Causes of low vision and blindness in children in a blind school in Lagos, Nigeria. West African journal of medicine. vol 21. issue 1. 2002-07-24. PMID:12081349. |
the anatomical sites of diseases leading to low vision and blindness in these children were retina (30.8%), lens (23.1%), glaucoma (19.2%), cornea (11.5%) and optic nerve (7.7%). |
2002-07-24 |
2023-08-12 |
Not clear |
| Kazumi Norose, Akihiko Yano, Xiang-Ming Zhang, Elizabeth Blankenhorn, Ellen Heber-Kat. Mapping of genes involved in murine herpes simplex virus keratitis: identification of genes and their modifiers. Journal of virology. vol 76. issue 7. 2002-04-19. PMID:11884574. |
herpes simplex keratitis (hsk) is an inflammatory response to viral infection and self antigens in the cornea and is a major cause of blindness. |
2002-04-19 |
2023-08-12 |
mouse |
| Amélie v Saint André, Nathan M Blackwell, Laurie R Hall, Achim Hoerauf, Norbert W Brattig, Lars Volkmann, Mark J Taylor, Louise Ford, Amy G Hise, Jonathan H Lass, Eugenia Diaconu, Eric Pearlma. The role of endosymbiotic Wolbachia bacteria in the pathogenesis of river blindness. Science (New York, N.Y.). vol 295. issue 5561. 2002-04-02. PMID:11884755. |
using a murine model for river blindness in which soluble extracts of filarial nematodes were injected into the corneal stroma, we demonstrated that the predominant inflammatory response in the cornea was due to species of endosymbiotic wolbachia bacteria. |
2002-04-02 |
2023-08-12 |
Not clear |
| L R Hall, E Diaconu, E Pearlma. A dominant role for Fc gamma receptors in antibody-dependent corneal inflammation. Journal of immunology (Baltimore, Md. : 1950). vol 167. issue 2. 2001-10-04. PMID:11441099. |
our studies on a mouse model of river blindness showed that ab production is essential for recruitment of neutrophils and eosinophils to the cornea and for development of corneal opacification. |
2001-10-04 |
2023-08-12 |
mouse |
| J T Kaifi, E Diaconu, E Pearlma. Distinct roles for PECAM-1, ICAM-1, and VCAM-1 in recruitment of neutrophils and eosinophils to the cornea in ocular onchocerciasis (river blindness). Journal of immunology (Baltimore, Md. : 1950). vol 166. issue 11. 2001-08-16. PMID:11359838. |
distinct roles for pecam-1, icam-1, and vcam-1 in recruitment of neutrophils and eosinophils to the cornea in ocular onchocerciasis (river blindness). |
2001-08-16 |
2023-08-12 |
Not clear |
| C Vinagre, M J Martínez, M Vogel, L Traipe, J Stoppel, O Squella, M Srur, R Charlí. [Role of Herpes simplex virus in the immune stromal keratitis]. Revista medica de Chile. vol 129. issue 3. 2001-06-21. PMID:11372292. |
herpes simplex virus (hsv) infection of the cornea is a leading cause of blindness in occidental countries and a common recurrent manifestation of it is the immune stromal keratitis (isk). |
2001-06-21 |
2023-08-12 |
Not clear |
| L R Hall, E Diaconu, R Patel, E Pearlma. CXC chemokine receptor 2 but not C-C chemokine receptor 1 expression is essential for neutrophil recruitment to the cornea in helminth-mediated keratitis (river blindness). Journal of immunology (Baltimore, Md. : 1950). vol 166. issue 6. 2001-05-17. PMID:11238651. |
cxc chemokine receptor 2 but not c-c chemokine receptor 1 expression is essential for neutrophil recruitment to the cornea in helminth-mediated keratitis (river blindness). |
2001-05-17 |
2023-08-12 |
mouse |
| L R Hall, E Diaconu, R Patel, E Pearlma. CXC chemokine receptor 2 but not C-C chemokine receptor 1 expression is essential for neutrophil recruitment to the cornea in helminth-mediated keratitis (river blindness). Journal of immunology (Baltimore, Md. : 1950). vol 166. issue 6. 2001-05-17. PMID:11238651. |
to identify mediators of granulocyte recruitment to the corneal stroma, we determined the relative contribution of chemokine receptors cxc chemokine receptor (cxcr)-2 (il-8r homologue) and ccr1 using a murine model of ocular onchocerciasis (river blindness) in which neutrophils and eosinophils migrate from peripheral vessels to the central cornea. |
2001-05-17 |
2023-08-12 |
mouse |
| J P Whitcher, M Srinivasan, M P Upadhya. Corneal blindness: a global perspective. Bulletin of the World Health Organization. vol 79. issue 3. 2001-04-26. PMID:11285665. |
diseases affecting the cornea are a major cause of blindness worldwide, second only to cataract in overall importance. |
2001-04-26 |
2023-08-12 |
Not clear |