| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| I-Lun Tsai, Chih-Chien Hsu, Kuo-Hsuan Hung, Chi-Wen Chang, Yung-Hsin Chen. Applications of biomaterials in corneal wound healing. Journal of the Chinese Medical Association : JCMA. vol 78. issue 4. 2016-12-23. PMID:25455161. |
disease affecting the cornea is a common cause of blindness worldwide. |
2016-12-23 |
2023-08-13 |
Not clear |
| Maritza Omaña-Molina, Virginia Vanzzini-Zago, Dolores Hernandez-Martinez, Arturo Gonzalez-Robles, Lizbeth Salazar-Villatoro, Elizabeth Ramirez-Flores, Eric Oregon-Miranda, Jacob Lorenzo-Morales, Adolfo Martinez-Palom. Acanthamoeba genotypes T3 and T4 as causative agents of amoebic keratitis in Mexico. Parasitology research. vol 115. issue 2. 2016-12-13. PMID:26581373. |
some genera included in this group act as opportunistic pathogens causing fatal encephalitis and acanthamoeba keratitis (ak), a sight-threatening infection of the cornea associated with the use of soft contact lenses that could even end in blindness if an early diagnosis and treatment are not achieved. |
2016-12-13 |
2023-08-13 |
Not clear |
| Ching-Yao Tsai, Lin-Chung Woung, Jiin-Cherng Yen, Po-Chen Tseng, Shih-Hwa Chiou, Yen-Jen Sung, Kuan-Ting Liu, Yung-Hsin Chen. Thermosensitive chitosan-based hydrogels for sustained release of ferulic acid on corneal wound healing. Carbohydrate polymers. vol 135. 2016-08-18. PMID:26453882. |
oxidative damage to cornea can be induced by alkaline chemical burn which may cause vision loss or blindness. |
2016-08-18 |
2023-08-13 |
rabbit |
| Xun Jie Jeesmond Hong, V K Shinoj, V M Murukeshan, M Baskaran, T Aun. A simple and non-contact optical imaging probe for evaluation of corneal diseases. The Review of scientific instruments. vol 86. issue 9. 2016-07-07. PMID:26429443. |
corneal disease is one of the leading causes of blindness worldwide, and a possible way of detection is by analyzing the shape and optical quality of the cornea. |
2016-07-07 |
2023-08-13 |
rabbit |
| Michelle R Mousel, James O Reynolds, Stephen N Whit. Genome-Wide Association Identifies SLC2A9 and NLN Gene Regions as Associated with Entropion in Domestic Sheep. PloS one. vol 10. issue 6. 2016-05-04. PMID:26098909. |
entropion is an inward rolling of the eyelid allowing contact between the eyelashes and cornea that may lead to blindness if not corrected. |
2016-05-04 |
2023-08-13 |
Not clear |
| Ann-Christin Bakker, Barbara Lange. [Cell-based therapies - an innovative therapeutic option in ophthalmology: Treating corneal diseases with stem cells]. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz. vol 58. issue 11-12. 2016-05-04. PMID:26459569. |
pathological changes and disorders of the cornea are a major cause of severe visual impairment and blindness. |
2016-05-04 |
2023-08-13 |
Not clear |
| Anthony Solomon, David Mabe. Trachoma. BMJ clinical evidence. vol 2007. 2016-04-22. PMID:19450349. |
infection can lead to scarring of the tarsal conjunctiva, inversion of the eyelashes so that they abrade the cornea (trichiasis), and corneal opacity, leading to blindness. |
2016-04-22 |
2023-08-12 |
Not clear |
| Vivek Singh, Sachin Shukla, Charanya Ramachandran, Dilip Kumar Mishra, Kishore R Katikireddy, Ikeda Lal, Sunil K Chauhan, Virender S Sangwa. Science and Art of Cell-Based Ocular Surface Regeneration. International review of cell and molecular biology. vol 319. 2016-04-12. PMID:26404466. |
the potential cause of blindness worldwide includes diseases of the cornea, ocular surface (limbal stem cell deficiency, allergic conjunctivitis, dry eye diseases), and retinal diseases. |
2016-04-12 |
2023-08-13 |
human |
| Xiaoyan Li, Huanfen Zhou, Weiqiang Tang, Qing Guo, Yan Zhan. Transient downregulation of microRNA-206 protects alkali burn injury in mouse cornea by regulating connexin 43. International journal of clinical and experimental pathology. vol 8. issue 3. 2016-03-10. PMID:26045777. |
chemical burn in cornea may cause permanent visual problem or complete blindness. |
2016-03-10 |
2023-08-13 |
mouse |
| Celine J Rocca, Alexander Kreymerman, Sarah N Ur, Katie E Frizzi, Swati Naphade, Athena Lau, Tammy Tran, Nigel A Calcutt, Jeffrey L Goldberg, Stephanie Cherqu. Treatment of Inherited Eye Defects by Systemic Hematopoietic Stem Cell Transplantation. Investigative ophthalmology & visual science. vol 56. issue 12. 2016-02-19. PMID:26540660. |
in eyes, crystals accumulate in the cornea causing photophobia and eventually blindness. |
2016-02-19 |
2023-08-13 |
mouse |
| Rowena M A Packer, Anke Hendricks, Charlotte C Bur. Impact of facial conformation on canine health: corneal ulceration. PloS one. vol 10. issue 5. 2016-02-05. PMID:25969983. |
corneal ulcers are a common and painful eye problem in domestic dogs that can lead to scarring and/or perforation of the cornea, potentially causing blindness. |
2016-02-05 |
2023-08-13 |
dog |
| Pierangela Rubino, Paolo Mora, Nicola Ungaro, Stefano A Gandolfi, Jelka G Orson. Anterior Segment Findings in Vitamin A Deficiency: A Case Series. Case reports in ophthalmological medicine. vol 2015. 2015-10-28. PMID:26509090. |
vitamin a deficiency is a rare but vision threatening disorder in the developed world, which can lead to blindness for severe keratomalacia with cornea scarring and perforation or night blindness due to impaired dark adaptation. |
2015-10-28 |
2023-08-13 |
Not clear |
| Kavitha Chikkanayakanahalli Venugopal, Suresh Ramappa Melsakkare, Sahana R Manipur, Pavana Acharya, Lakshmi Bomalapura Ramamurth. Potential for Hospital Based Corneal Retreival in Hassan District Hospital. Journal of clinical and diagnostic research : JCDR. vol 9. issue 8. 2015-10-05. PMID:26435976. |
considering the magnitude of corneal blindness and shortage of donor cornea, there is a huge gap in the demand and supply. |
2015-10-05 |
2023-08-13 |
Not clear |
| Yang Liu, Li Ren, Yingjun Wan. Crosslinked collagen-gelatin-hyaluronic acid biomimetic film for cornea tissue engineering applications. Materials science & engineering. C, Materials for biological applications. vol 33. issue 1. 2015-07-17. PMID:25428062. |
cornea disease may lead to blindness and keratoplasty is considered as an effective treatment method. |
2015-07-17 |
2023-08-13 |
human |
| Chastain Anderson, Qinbo Zhou, Shusheng Wan. An alkali-burn injury model of corneal neovascularization in the mouse. Journal of visualized experiments : JoVE. issue 86. 2015-06-10. PMID:24748032. |
neovascularization (nv) of the cornea, which can be caused by trauma, keratoplasty or infectious disease, breaks down the so called 'angiogenic privilege' of the cornea and forms the basis of multiple visual pathologies that may even lead to blindness. |
2015-06-10 |
2023-08-13 |
mouse |
| Rajkumar Patil, Ram Prasath E, Abhijit Boratne, Sanjeev Kumar Gupta, Shib Sekhar Datt. Status of eye donation awareness and its associated factors among adults in rural pondicherry. Journal of clinical and diagnostic research : JCDR. vol 9. issue 2. 2015-04-10. PMID:25859469. |
though all the causes of blindness can't be cured, corneal blindness can be reverted by corneal transplantation, for which a suitable donor cornea is required at right time. |
2015-04-10 |
2023-08-13 |
Not clear |
| Karl David Brown, Suet Low, Indumathi Mariappan, Keren Maree Abberton, Robert Short, Hong Zhang, Savitri Maddileti, Virender Sangwan, David Steele, Mark Daniel. Plasma polymer-coated contact lenses for the culture and transfer of corneal epithelial cells in the treatment of limbal stem cell deficiency. Tissue engineering. Part A. vol 20. issue 3-4. 2014-10-10. PMID:24328453. |
extensive damage to the limbal region of the cornea leads to a severe form of corneal blindness termed as limbal stem cell deficiency (lscd). |
2014-10-10 |
2023-08-12 |
human |
| Hong Ouyang, Yuanchao Xue, Ying Lin, Xiaohui Zhang, Lei Xi, Sherrina Patel, Huimin Cai, Jing Luo, Meixia Zhang, Ming Zhang, Yang Yang, Gen Li, Hairi Li, Wei Jiang, Emily Yeh, Jonathan Lin, Michelle Pei, Jin Zhu, Guiqun Cao, Liangfang Zhang, Benjamin Yu, Shaochen Chen, Xiang-Dong Fu, Yizhi Liu, Kang Zhan. WNT7A and PAX6 define corneal epithelium homeostasis and pathogenesis. Nature. vol 511. issue 7509. 2014-08-19. PMID:25030175. |
cornea epithelial cells (cecs) undergo continuous renewal from limbal stem or progenitor cells (lscs), and deficiency in lscs or corneal epithelium--which turns cornea into a non-transparent, keratinized skin-like epithelium--causes corneal surface disease that leads to blindness in millions of people worldwide. |
2014-08-19 |
2023-08-13 |
human |
| A M Shaibu, M Aminu, B O P Musa, M A Bugaj. Seroprevalence of IgG antibodies to herpes simplex virus type-1 in Nigerian children. Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria. vol 23. issue 1. 2014-07-10. PMID:24946453. |
herpes simplex virus type-1 (hsv-1) can cause chronic ulcerative infection in immunosuppressed children leading to latency with subsequent reactivate in the conjunctiva resulting in scarring, thickening of the cornea and blindness. |
2014-07-10 |
2023-08-13 |
Not clear |
| Hamad Al Fahaa. Keratitis-ichthyosis-deafness syndrome: first affected family reported in the Middle East. International medical case reports journal. vol 7. 2014-04-17. PMID:24741331. |
keratitis-ichthyosis-deafness (kid) syndrome is a rare congenital multisystem disorder affecting certain tissues of ectodermal origin such as epidermis, cochlea, and cornea, leading mainly to palmoplantar hyperkeratosis, ichthyosiform scaling, deafness, and blindness. |
2014-04-17 |
2023-08-13 |
Not clear |