| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yu-Chi Ma, Chang-Tsung Hsieh, Yu-Hsiang Lin, Chi-An Dai, Jia-Han L. Numerical Study of Customized Artificial Cornea Shape by Hydrogel Biomaterials on Imaging and Wavefront Aberration. Polymers. vol 13. issue 24. 2021-12-28. PMID:34960923. |
the blindness caused by cornea diseases has exacerbated many patients all over the world. |
2021-12-28 |
2023-08-13 |
Not clear |
| Huicong Hu, Shurong Wang, Yuxi He, Sitong Shen, Boyuan Yao, Duo Xu, Xin Liu, Yan Zhan. The role of bone morphogenetic protein 4 in corneal injury repair. Experimental eye research. vol 212. 2021-12-08. PMID:34537186. |
corneal injury may cause neovascularization and lymphangiogenesis in cornea which have a detrimental effect to vision and even lead to blindness. |
2021-12-08 |
2023-08-13 |
Not clear |
| Chang-Min Liang, Dar-Jen Hsieh, Fan-Wei Tseng, Periasamy Srinivasan, Ming-Long Yeh, Ming-Cheng Ta. Acellular Porcine Cornea Produced by Supercritical Carbon Dioxide Extraction: A Potential Substitute for Human Corneal Regeneration. Cornea. 2021-11-28. PMID:34839331. |
the aim of this study was to develop a non-cytotoxic, biocompatible innovative acellular porcine cornea (apc) for corneal wound healing and corneal blindness treatment. |
2021-11-28 |
2023-08-13 |
human |
| Jutaro Nakamura, Masaki Takeuchi, Masao Ota, Nobuhisa Mizuki, Shigeaki Ohn. Does the interaction of KIR and HLA affect the development of non-infectious uveitis? Current molecular medicine. 2021-10-29. PMID:34711163. |
immune tolerance is established in the eye to prevent permanent blindness associated with destructive damage to the cornea and retina caused by immune cell infiltration; hence, the immune responses and subsequent inflammations are strongly suppressed. |
2021-10-29 |
2023-08-13 |
human |
| Veronica Hidalgo-Alvarez, Hala S Dhowre, Olivia A Kingston, Carl M Sheridan, Hannah J Levi. Biofabrication of Artificial Stem Cell Niches in the Anterior Ocular Segment. Bioengineering (Basel, Switzerland). vol 8. issue 10. 2021-10-26. PMID:34677208. |
loss of transparency to the cornea or lens (cataract) and dysfunctional regulation of intra ocular pressure (glaucoma) are leading causes of worldwide blindness. |
2021-10-26 |
2023-08-13 |
Not clear |
| . [Chinese expert consensus on keratoprosthesis procedure (2021)]. [Zhonghua yan ke za zhi] Chinese journal of ophthalmology. vol 57. issue 10. 2021-10-11. PMID:34619942. |
with the approval of the collar button design kpro (boston Ⅰ-like artificial cornea) for marketing and the completion of clinical trials of the miok kpro (micof-like artificial cornea) in china, domestic artificial corneas will bring chinese patients with end-stage corneal blindness opportunities for recovery of eyesight. |
2021-10-11 |
2023-08-13 |
Not clear |
| Alyaa A Albadr, Ismaiel A Tekko, Lalitkumar K Vora, Ahlam A Ali, Garry Laverty, Ryan F Donnelly, Raghu Raj Singh Thaku. Rapidly dissolving microneedle patch of amphotericin B for intracorneal fungal infections. Drug delivery and translational research. 2021-07-24. PMID:34302273. |
chronic fungal infection of the cornea could lead to blindness if not treated properly. |
2021-07-24 |
2023-08-13 |
Not clear |
| Shibaji Gupta, Seshadri Kole, Saikat Bhattacharya, Debjani Guchhai. Perception and Willingness towards Eye Donation in an urban community of West Bengal. Nepalese journal of ophthalmology : a biannual peer-reviewed academic journal of the Nepal Ophthalmic Society : NEPJOPH. vol 12. issue 24. 2021-06-24. PMID:33978624. |
with 1.2 million existing cases of corneal blindness in india, the demand for cornea collection is increasing. |
2021-06-24 |
2023-08-13 |
Not clear |
| Pui-Chuen Hui, Katia Shtyrkova, Chengxin Zhou, Xiaoniao Chen, James Chodosh, Claes H Dohlman, Eleftherios I Paschali. Implantable self-aligning fiber-optic optomechanical devices for in vivo intraocular pressure-sensing in artificial cornea. Journal of biophotonics. vol 13. issue 7. 2021-06-23. PMID:32246524. |
artificial cornea is an effective treatment of corneal blindness. |
2021-06-23 |
2023-08-13 |
rabbit |
| Xiaokun Wang, Shoumyo Majumdar, Uri Soiberman, Joshua N Webb, Liam Chung, Giuliano Scarcelli, Jennifer H Elisseef. Multifunctional synthetic Bowman's membrane-stromal biomimetic for corneal reconstruction. Biomaterials. vol 241. 2021-05-14. PMID:32097748. |
as the outermost layer of the eye, the cornea is vulnerable to physical and chemical trauma, which can result in loss of transparency and lead to corneal blindness. |
2021-05-14 |
2023-08-13 |
rabbit |
| Lokendrakumar C Bengani, Hidenaga Kobashi, Amy E Ross, Hualei Zhai, Borja Salvador-Culla, Rekha Tulsan, Paraskevi E Kolovou, Sharad K Mittal, Sunil K Chauhan, Daniel S Kohane, Joseph B Ciolin. Steroid-eluting contact lenses for corneal and intraocular inflammation. Acta biomaterialia. vol 116. 2021-05-14. PMID:32814140. |
the cornea) or inside the eye, both of which can result in loss of vision or even blindness. |
2021-05-14 |
2023-08-13 |
rabbit |
| Lijie Xie, Chen Ouyang, Jianping Ji, Jing Wu, Xiaojuan Dong, Chao Hou, Ting Huan. Construction of bioengineered corneal stromal implants using an allogeneic cornea-derived matrix. Materials science & engineering. C, Materials for biological applications. vol 120. 2021-05-14. PMID:33545838. |
the bioengineering of corneal scaffolds that mimic native human cornea has attracted interest owing to the scarcity of donor corneas for the transplantation-based treatment of corneal blindness. |
2021-05-14 |
2023-08-13 |
human |
| Yu Qin, Yixin Yu, Julia Fu, Xinyi Xie, Tao Wang, Maria A Woodward, Yannis M Paulus, Xinmai Yang, Xueding Wan. Photo-Mediated Ultrasound Therapy for the Treatment of Corneal Neovascularization in Rabbit Eyes. Translational vision science & technology. vol 9. issue 13. 2021-05-12. PMID:33344060. |
corneal neovascularization (cnv) is the invasion of new blood vessels into the avascular cornea, leading to reduced corneal transparency and visual acuity, impaired vision, and even blindness. |
2021-05-12 |
2023-08-13 |
rabbit |
| Galina S Baturina, Lubov E Katkova, Irina G Palchikova, Nataliya G Kolosova, Evgeniy I Solenov, Igor A Iskako. Mitochondrial Antioxidant SkQ1 Improves Hypothermic Preservation of the Cornea. Biochemistry. Biokhimiia. vol 86. issue 3. 2021-05-10. PMID:33838637. |
diseases of the cornea are a frequent cause of blindness worldwide. |
2021-05-10 |
2023-08-13 |
Not clear |
| Promita Bhattacharjee, Mark Ahearn. Significance of Crosslinking Approaches in the Development of Next Generation Hydrogels for Corneal Tissue Engineering. Pharmaceutics. vol 13. issue 3. 2021-04-13. PMID:33671011. |
medical conditions such as trachoma, keratoconus and fuchs endothelial dystrophy can damage the cornea, leading to visual deterioration and blindness and necessitating a cornea transplant. |
2021-04-13 |
2023-08-13 |
Not clear |
| D Gongal, S Thakur, A Panse, R Pawar, C Q Yu, C D Foste. THERMAL ANALYSIS OF INTRAOCULAR ELECTRONIC DISPLAY PROJECTOR VISUAL PROSTHESIS. Numerical heat transfer. Part A, Applications. vol 78. issue 12. 2021-04-01. PMID:33776378. |
with corneal opacity, light is unable to pass through the cornea to form a clear image on the retina, resulting in blindness. |
2021-04-01 |
2023-08-13 |
Not clear |
| Jose M Vargas, Eric Shiue. A Foldable Nonpenetrating Keratoprosthesis: Medium to Long-Term Clinical Results in Patients with Corneal Blindness due to Noninflammatory Anterior Cornea Disease. Middle East African journal of ophthalmology. vol 27. issue 3. 2021-01-29. PMID:33488010. |
a foldable nonpenetrating keratoprosthesis: medium to long-term clinical results in patients with corneal blindness due to noninflammatory anterior cornea disease. |
2021-01-29 |
2023-08-13 |
Not clear |
| Jose M Vargas, Eric Shiue. A Foldable Nonpenetrating Keratoprosthesis: Medium to Long-Term Clinical Results in Patients with Corneal Blindness due to Noninflammatory Anterior Cornea Disease. Middle East African journal of ophthalmology. vol 27. issue 3. 2021-01-29. PMID:33488010. |
to report the medium to long-term safety and performance outcomes of the keraklear nonpenetrating artificial cornea (keraklear) as the primary procedure in patients with corneal blindness due to noninflammatory anterior cornea disease. |
2021-01-29 |
2023-08-13 |
Not clear |
| Maria Xeroudaki, Muthukumar Thangavelu, Anton Lennikov, Anjula Ratnayake, Jovana Bisevac, Goran Petrovski, Per Fagerholm, Mehrdad Rafat, Neil Lagal. A porous collagen-based hydrogel and implantation method for corneal stromal regeneration and sustained local drug delivery. Scientific reports. vol 10. issue 1. 2021-01-12. PMID:33037282. |
biomaterials designed to replace the diseased cornea could be used to treat corneal blindness where human donor tissue is in short supply, but challenges are the integration of biomaterials with host tissue and cells, avoiding a rapid material degradation and maintaining corneal transparency. |
2021-01-12 |
2023-08-13 |
human |
| Anandalakshmi Venkatraman, Elavazhagan Murugan, Shu Jun Lin, Gary Swee Lim Peh, Lakshminarayanan Rajamani, Jodhbir S Meht. Effect of osmolytes on in-vitro aggregation properties of peptides derived from TGFBIp. Scientific reports. vol 10. issue 1. 2020-11-09. PMID:32132634. |
tgfbi-associated corneal dystrophies are protein aggregation disorders in which the mutant tgfbip aggregates and accumulates in the cornea, leading to a reduction in visual acuity and blindness in severe cases. |
2020-11-09 |
2023-08-13 |
human |