| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hideki Miura, Yu Ando, Yukihiro Noda, Kenichi Isobe, Norio Ozak. Long-lasting effects of inescapable-predator stress on brain tryptophan metabolism and the behavior of juvenile mice. Stress (Amsterdam, Netherlands). vol 14. issue 3. 2011-08-05. PMID:21294659. |
behavior on an elevated plus-maze, and trp, kyn, and 5-ht levels in the prefrontal cortex, hippocampus, amygdala, and dorsal raphe nuclei were measured 1 and 4 weeks after stress exposure. |
2011-08-05 |
2023-08-12 |
mouse |
| Hideki Miura, Yu Ando, Yukihiro Noda, Kenichi Isobe, Norio Ozak. Long-lasting effects of inescapable-predator stress on brain tryptophan metabolism and the behavior of juvenile mice. Stress (Amsterdam, Netherlands). vol 14. issue 3. 2011-08-05. PMID:21294659. |
predator stress increased kyn levels in the prefrontal cortex (until 4 weeks after stress exposure) and dorsal raphe nuclei (for 1 week after stress exposure), decreased 5-ht levels in all brain regions (until 4 weeks after stress exposure). |
2011-08-05 |
2023-08-12 |
mouse |
| Florent G Revel, Jean-Luc Moreau, Raul R Gainetdinov, Amyaouch Bradaia, Tatyana D Sotnikova, Roland Mory, Sean Durkin, Katrin Groebke Zbinden, Roger Norcross, Claas A Meyer, Veit Metzler, Sylvie Chaboz, Laurence Ozmen, Gerhard Trube, Bruno Pouzet, Bernhard Bettler, Marc G Caron, Joseph G Wettstein, Marius C Hoene. TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 20. 2011-07-26. PMID:21525407. |
furthermore, modulation of taar1 activity altered the desensitization rate and agonist potency at 5-ht(1a) receptors in the dorsal raphe, suggesting that taar1 modulates not only dopaminergic but also serotonergic neurotransmission. |
2011-07-26 |
2023-08-12 |
mouse |
| Robert R Rozeske, Benjamin N Greenwood, Monika Fleshner, Linda R Watkins, Steven F Maie. Voluntary wheel running produces resistance to inescapable stress-induced potentiation of morphine conditioned place preference. Behavioural brain research. vol 219. issue 2. 2011-07-13. PMID:21262267. |
in rodents, exposure to acute inescapable, but not escapable, stress potentiates morphine conditioned place preference (cpp), an effect that is dependent upon hyperactivation of serotonin (5-ht) neurons in the dorsal raphe nucleus (drn). |
2011-07-13 |
2023-08-12 |
Not clear |
| S J Bang, K G Common. Age-dependent effects of initial exposure to nicotine on serotonin neurons. Neuroscience. vol 179. 2011-07-13. PMID:21277949. |
as the dorsal raphe (dr) and median raphe (mnr) nuclei are the primary 5-ht source to the forebrain, the current study tested the hypothesis that there are age-dependent effects of acute nicotine administration on activation of 5-ht neurons within these regions. |
2011-07-13 |
2023-08-12 |
rat |
| Alexandre Bonnin, Nick Goeden, Kevin Chen, Melissa L Wilson, Jennifer King, Jean C Shih, Randy D Blakely, Evan S Deneris, Pat Levit. A transient placental source of serotonin for the fetal forebrain. Nature. vol 472. issue 7343. 2011-06-23. PMID:21512572. |
to examine putative central and peripheral sources of embryonic brain 5-ht, we used pet1(-/-) (also called fev) mice in which most dorsal raphe neurons lack 5-ht. |
2011-06-23 |
2023-08-12 |
mouse |
| Roger L H Pobbe, Helio Zangrossi, D Caroline Blanchard, Robert J Blanchar. Involvement of dorsal raphe nucleus and dorsal periaqueductal gray 5-HT receptors in the modulation of mouse defensive behaviors. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 21. issue 4. 2011-06-15. PMID:20570114. |
involvement of dorsal raphe nucleus and dorsal periaqueductal gray 5-ht receptors in the modulation of mouse defensive behaviors. |
2011-06-15 |
2023-08-12 |
mouse |
| Keiko Ohoyama, Satoshi Yamamura, Tatsuya Hamaguchi, Masanori Nakagawa, Eishi Motomura, Takashi Shiroyama, Hisashi Tanii, Motohiro Okad. Effect of novel atypical antipsychotic, blonanserin, on extracellular neurotransmitter level in rat prefrontal cortex. European journal of pharmacology. vol 653. issue 1-3. 2011-05-02. PMID:21147094. |
to clarify the mechanisms of action of blonanserin, an atypical antipsychotic drug, we studied the effects of systemic administration of blonanserin and risperidone on extracellular levels of norepinephrine, dopamine, serotonin, gaba and glutamate in the medial prefrontal cortex using microdialysis, and neuronal firing in the ventral tegmental area, locus coeruleus, dorsal raphe nucleus and mediodorsal thalamic nucleus using radiotelemetry. |
2011-05-02 |
2023-08-12 |
rat |
| Kayoko W Miyazaki, Katsuhiko Miyazaki, Kenji Doy. Activation of the central serotonergic system in response to delayed but not omitted rewards. The European journal of neuroscience. vol 33. issue 1. 2011-04-14. PMID:21070390. |
we simultaneously measured the levels of serotonin and dopamine in the dorsal raphe nucleus using in vivo microdialysis. |
2011-04-14 |
2023-08-12 |
rat |
| Marilyn J Duncan, Matthew R Congleto. Neural mechanisms mediating circadian phase resetting by activation of 5-HT(7) receptors in the dorsal raphe: roles of GABAergic and glutamatergic neurotransmission. Brain research. vol 1366. 2011-03-21. PMID:20920493. |
neural mechanisms mediating circadian phase resetting by activation of 5-ht(7) receptors in the dorsal raphe: roles of gabaergic and glutamatergic neurotransmission. |
2011-03-21 |
2023-08-12 |
Not clear |
| Marilyn J Duncan, Matthew R Congleto. Neural mechanisms mediating circadian phase resetting by activation of 5-HT(7) receptors in the dorsal raphe: roles of GABAergic and glutamatergic neurotransmission. Brain research. vol 1366. 2011-03-21. PMID:20920493. |
5-ht(7) receptors in the dorsal raphe nucleus (drn) influence circadian rhythms, sleep, and serotonin release. |
2011-03-21 |
2023-08-12 |
Not clear |
| J V Schweimer, M A Ungles. Phasic responses in dorsal raphe serotonin neurons to noxious stimuli. Neuroscience. vol 171. issue 4. 2011-03-10. PMID:20888395. |
phasic responses in dorsal raphe serotonin neurons to noxious stimuli. |
2011-03-10 |
2023-08-12 |
rat |
| J V Schweimer, M A Ungles. Phasic responses in dorsal raphe serotonin neurons to noxious stimuli. Neuroscience. vol 171. issue 4. 2011-03-10. PMID:20888395. |
we found that, in the dorsal raphe of anesthetized rats, most neurochemically-identified clocklike serotonin neurons were phasically excited by noxious footshocks, whereas most bursting serotonin neurons were inhibited. |
2011-03-10 |
2023-08-12 |
rat |
| Julie A Wixey, Hanna E Reinebrant, Kathryn M Bulle. Inhibition of neuroinflammation prevents injury to the serotonergic network after hypoxia-ischemia in the immature rat brain. Journal of neuropathology and experimental neurology. vol 70. issue 1. 2011-03-07. PMID:21157380. |
we used a postnatal day 3 rat model of preterm hi and found parallel reductions in the 5-ht transporter expression, 5-ht levels and numbers of 5-ht-positive dorsal raphe neurons 1 week after insult. |
2011-03-07 |
2023-08-12 |
human |
| Y Yao, P J Bergold, N J Peningto. Acute Ca(2+)-dependent desensitization of 5-HT(1A) receptors is mediated by activation of protein kinase A (PKA) in rat serotonergic neurons. Neuroscience. vol 169. issue 1. 2011-03-04. PMID:20423724. |
this report investigates acute changes in the sensitivity of 5-ht(1a) receptors in dorsal raphe (dr) neurons in response to elevated serotonin. |
2011-03-04 |
2023-08-12 |
rat |
| S E Gartside, N C Griffith, V Kaura, C D Ingra. The neurosteroid dehydroepiandrosterone (DHEA) and its metabolites alter 5-HT neuronal activity via modulation of GABAA receptors. Journal of psychopharmacology (Oxford, England). vol 24. issue 11. 2011-02-28. PMID:19493957. |
the firing of presumed 5-ht neurones in a slice preparation containing rat dorsal raphe nucleus was inhibited by the gaba(a) receptor agonists 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridinyl-3-ol (thip) (25 μm) and gaba (100 μm). |
2011-02-28 |
2023-08-12 |
rat |
| Katsuhiko Miyazaki, Kayoko W Miyazaki, Kenji Doy. Activation of dorsal raphe serotonin neurons underlies waiting for delayed rewards. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 2. 2011-02-22. PMID:21228157. |
activation of dorsal raphe serotonin neurons underlies waiting for delayed rewards. |
2011-02-22 |
2023-08-12 |
rat |
| Yuefeng Lu, Kimberly L Simpson, Kristin J Weaver, Rick C S Li. Coexpression of serotonin and nitric oxide in the raphe complex: cortical versus subcortical circuit. Anatomical record (Hoboken, N.J. : 2007). vol 293. issue 11. 2011-02-10. PMID:20734426. |
our data demonstrated that: (1) a significant number of raphe-cortical projecting neurons was identified not only in the midline subgroup of dorsal raphe (b6, 7) but also in the median raphe (b8), as well as in the supralemniscal nucleus (b9); (2) serotonergic cortical projecting neurons from these three raphe nuclei exhibited a high (>80%) percentage of coexpression with nnos immunoreactivity; (3) similarly, serotonin transporter immunoreactive fibers in the medial prefrontal cortex were also double-labeled with nnos immunoreactivity; (4) in contrast, the descending spinal cord projecting raphe nuclei revealed only tph but not nnos immunoreactivity. |
2011-02-10 |
2023-08-12 |
Not clear |
| Christophe M Lamy, Sheryl G Bec. Swim stress differentially blocks CRF receptor mediated responses in dorsal raphe nucleus. Psychoneuroendocrinology. vol 35. issue 9. 2011-02-02. PMID:20399020. |
modulation of the serotonergic (5-ht) neurotransmitter system arising from the dorsal raphe nucleus (dr) is thought to support the behavioral effects of swim stress, i.e., immobility. |
2011-02-02 |
2023-08-12 |
rat |
| C L Bethea, A P Redd. Effect of ovarian hormones on genes promoting dendritic spines in laser-captured serotonin neurons from macaques. Molecular psychiatry. vol 15. issue 10. 2011-01-13. PMID:19687787. |
the data indicate that ovarian steroids target gene expression of the rho gtpases and pivotal downstream proteins, that in turn would promote dendritic spine proliferation and stabilization on serotonin neurons of the dorsal raphe nucleus. |
2011-01-13 |
2023-08-12 |
Not clear |