| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Heimberg, R A Komoroski, W B Lawson, D Cardwell, C N Karso. Regional proton magnetic resonance spectroscopy in schizophrenia and exploration of drug effect. Psychiatry research. vol 83. issue 2. 1999-05-04. PMID:9818736. |
in schizophrenic patients treated with atypical antipsychotics, decreased levels of choline were found in the left basal ganglia, while increased levels of n-acetylaspartate were found in the left frontal cortex. |
1999-05-04 |
2023-08-12 |
human |
| S I Chefer, A G Horti, K S Lee, A O Koren, D W Jones, J G Gorey, J M Links, A G Mukhin, D R Weinberger, E D Londo. In vivo imaging of brain nicotinic acetylcholine receptors with 5-[123I]iodo-A-85380 using single photon emission computed tomography. Life sciences. vol 63. issue 25. 1999-01-08. PMID:9870715. |
at 2.5 h after cytisine administration, radioactivity in the thalamus was reduced by 84%, in the frontal cortex, by 76%, and in the basal ganglia, by 57% of the level measured at the time of cytisine administration, demonstrating that the binding was reversible. |
1999-01-08 |
2023-08-12 |
human |
| O Hikosaka, K Miyashita, S Miyachi, K Sakai, X L. Differential roles of the frontal cortex, basal ganglia, and cerebellum in visuomotor sequence learning. Neurobiology of learning and memory. vol 70. issue 1-2. 1998-11-10. PMID:9753593. |
differential roles of the frontal cortex, basal ganglia, and cerebellum in visuomotor sequence learning. |
1998-11-10 |
2023-08-12 |
Not clear |
| J Kass. [Comparison of the reactivation effects of the HI-6 oxime and obidoximeon cyclosin-inhibited acetylcholinesterase in the diaphragm and various parts of the brain in rats]. Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti. vol 47. issue 1. 1998-06-23. PMID:9600150. |
in experiments on male rats the reactivating effects of oxime hi-6 and obidoxime in combination with atropine on acetylcholinesterase, inhibited by the highly toxic organophoshate cyclosin, were compared in various parts of the brain (frontal cortex, pontomedullar region, hypothalamus, hippocampus, basal ganglia) and the diaphragm. |
1998-06-23 |
2023-08-12 |
rat |
| P Tibbo, P H Silverstone, A J McEwan, J Scott, A Joshua, K Golber. A single photon emission computed tomography scan study of striatal dopamine D2 receptor binding with 123I-epidepride in patients with schizophrenia and controls. Journal of psychiatry & neuroscience : JPN. vol 22. issue 1. 1997-02-12. PMID:9002391. |
there was a trend for the total striatal binding of medicated patients with schizophrenia, as measured by total basal ganglia: frontal cortex (tbg:fc) ratios, to be less than the binding of controls (p = 0.053). |
1997-02-12 |
2023-08-12 |
Not clear |
| G M Goodwi. Functional imaging, affective disorder and dementia. British medical bulletin. vol 52. issue 3. 1997-01-13. PMID:8949253. |
the most consistent findings in both primary major depression and in secondary depression have been reductions in inferior frontal cortex, adjacent cingulate cortex, temporal cortex and basal nuclei. |
1997-01-13 |
2023-08-12 |
Not clear |
| H Shibasak. [Pathophysiology of involuntary movements--dystonia and myoclonus from viewpoint of brain activities]. Rinsho shinkeigaku = Clinical neurology. vol 35. issue 12. 1996-12-04. PMID:8752405. |
changes in regional cerebral blood flow (rcbf) studied by positron emission tomography (pet) during movements in patients with dystonia were inconsistent with regard to s1-m1, but the frontal cortex including the rostral sma was shown to be overactivated, suggesting the thalamocortical disinhibition based on the basal ganglia disorders. |
1996-12-04 |
2023-08-12 |
Not clear |
| W H Mec. Neuropharmacology of timing and time perception. Brain research. Cognitive brain research. vol 3. issue 3-4. 1996-11-27. PMID:8806025. |
for example, the internal clock used to time durations in the seconds-to-minutes range appears linked to dopamine (da) function in the basal ganglia, while temporal memory and attentional mechanisms appear linked to acetylcholine (ach) function in the frontal cortex. |
1996-11-27 |
2023-08-12 |
human |
| M P Deiber, V Ibañez, N Sadato, M Hallet. Cerebral structures participating in motor preparation in humans: a positron emission tomography study. Journal of neurophysiology. vol 75. issue 1. 1996-11-12. PMID:8822554. |
in comparison with a "rest" condition, which had matched visual inputs, the different conditions of motor preparation were associated with increased rcbf in a common set of cerebral regions: the contralateral frontal cortex (sensorimotor, premotor, cingulate, and supplementary motor cortex), the contralateral parietal association cortex (anterior and posterior regions), the ipsilateral cerebellum, the contralateral basal ganglia, and the thalamus. |
1996-11-12 |
2023-08-12 |
human |
| M Y Osman, S M Abdel Tawab, I A Shara. Effect of physostigmine on cholinesterase activity in different parts of rat brain. Arzneimittel-Forschung. vol 45. issue 6. 1995-09-15. PMID:7646566. |
inhibition of acetylcholinesterase (ache) in the whole brain, cerebellum, pons, frontal cortex, basal ganglia and medulla oblongata of rat brain by physostigmine (cas 57-47-6) in vitro was studied. |
1995-09-15 |
2023-08-12 |
rat |
| J T Kuikka, J Tiihonen, K A Bergström, J Karhu, P Hartikainen, H Viinamäki, E Länsimies, J Lehtonen, P Hakol. Imaging of serotonin and dopamine transporters in the living human brain. European journal of nuclear medicine. vol 22. issue 4. 1995-08-16. PMID:7607266. |
the [123i] beta-cit distribution showed the most prominent 5-ht activity in the medial frontal cortex, hypothalamus, midbrain and occipital cortex and the greatest da activity in the basal ganglia. |
1995-08-16 |
2023-08-12 |
human |
| J T Kuikka, J Tiihonen, K A Bergström, J Karhu, P Hartikainen, H Viinamäki, E Länsimies, J Lehtonen, P Hakol. Imaging of serotonin and dopamine transporters in the living human brain. European journal of nuclear medicine. vol 22. issue 4. 1995-08-16. PMID:7607266. |
the specific binding of the 5-ht transporters in the medial frontal cortex was 0.377 +/- 0.031 and that of the da transporters in the basal ganglia, 0.916 +/- 0.007. |
1995-08-16 |
2023-08-12 |
human |
| J Bajgar, J Fusek, F Skope. Changes of cholinesterases in the blood and some tissues following administration of tacrin and its two derivatives to rats. Neurochemistry international. vol 24. issue 6. 1995-01-03. PMID:7981637. |
administered to rats in a dose of 1.2 x ld50 and acetylcholinesterase (blood, hippocampus, frontal cortex, basal ganglia, septum and diaphragm) or butyrylcholinesterase (liver) activities were detected. |
1995-01-03 |
2023-08-12 |
rat |
| G Arnold, K Tatsch, W H Oertel, T Vogl, J Schwarz, E Kraft, C M Kirsc. Clinical progressive supranuclear palsy: differential diagnosis by IBZM-SPECT and MRI. Journal of neural transmission. Supplementum. vol 42. 1994-12-22. PMID:7964681. |
specific striatal dopamine d2 receptor binding in ibzm-spect, as calculated by a basal ganglia to frontal cortex ratio (bg/fc) was reduced in 5 patients, but normal in 3 patients. |
1994-12-22 |
2023-08-12 |
Not clear |
| S Przedborski, N Giladi, S Takikawa, T Ishikawa, V Dhawan, P Spetsieris, T Chaly, S Fahn, D Eidelber. Metabolic topography of the hemiparkinsonism-hemiatrophy syndrome. Neurology. vol 44. issue 9. 1994-10-28. PMID:7936286. |
all six hpha patients demonstrated significant metabolic reductions (> 3 sd) in the contralateral basal ganglia or frontal cortex as compared with normal control values. |
1994-10-28 |
2023-08-12 |
human |
| B H Guze, M Gitli. The neuropathologic basis of major affective disorders: neuroanatomic insights. The Journal of neuropsychiatry and clinical neurosciences. vol 6. issue 2. 1994-08-31. PMID:8044032. |
data that emerge from these sources implicate the basal ganglia, frontal cortex, and temporal lobes in the production of mood disorder symptoms. |
1994-08-31 |
2023-08-12 |
Not clear |
| J Bajgar, F Skope. Changes of rat blood and tissue cholinesterases following administration of tacrine derivatives in vivo. Sbornik vedeckych praci Lekarske fakulty Karlovy university v Hradci Kralove. vol 36. issue 1-2. 1994-05-23. PMID:8165433. |
acetylcholinesterase (blood, hippocampus, frontal cortex, basal ganglia, septum and diaphragm) or butyrylcholinesterase (liver) activities following i.m. |
1994-05-23 |
2023-08-12 |
rat |
| H R Weiss, A K Sinh. Imbalance of regional cerebral blood flow and oxygen consumption: effect of vascular alpha adrenoceptor blockade. Neuropharmacology. vol 32. issue 3. 1993-05-17. PMID:8097301. |
with n-methyl chlorpromazine, cerebral blood flow in the basal ganglia was greater than all other regions, except the frontal cortex. |
1993-05-17 |
2023-08-12 |
rat |
| M Chavko, E M Nemoto, J A Melic. Regional lipid composition in the rat brain. Molecular and chemical neuropathology. vol 18. issue 1-2. 1993-05-07. PMID:8466586. |
total lipid content was highest (p < 0.05) in the medulla oblongata (111.0 +/- 6.0 mg/g wet brain, x +/- sd) followed by the hippocampus (72.6 +/- 2.8), cerebellum (62.7 +/- 4.6), basal ganglia (62.6 +/- 1.5), frontal cortex (57.7 +/- 2.1), and entorhinal cortex (53.3 +/- 1.9). |
1993-05-07 |
2023-08-12 |
rat |
| W Schultz, R Rom. Role of primate basal ganglia and frontal cortex in the internal generation of movements. I. Preparatory activity in the anterior striatum. Experimental brain research. vol 91. issue 3. 1993-02-16. PMID:1483512. |
the purpose of these studies was to investigate neuronal activity in the basal ganglia and frontal cortex in relation to the internal generation of goal-directed movements. |
1993-02-16 |
2023-08-11 |
monkey |