| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M P Laakso, O Vaurio, E Koivisto, L Savolainen, M Eronen, H J Aronen, P Hakola, E Repo, H Soininen, J Tiihone. Psychopathy and the posterior hippocampus. Behavioural brain research. vol 118. issue 2. 2001-05-10. PMID:11164516. |
these data are in accordance with experimental studies proposing that lesions of the dorsal hippocampus impair acquisition of conditioned fear, and with theories on psychopathology according to which one of the central features in the birth of psychopathy is a deficit in acquisition of conditioned fear. |
2001-05-10 |
2023-08-12 |
human |
| A Rotenberg, T Abel, R D Hawkins, E R Kandel, R U Mulle. Parallel instabilities of long-term potentiation, place cells, and learning caused by decreased protein kinase A activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 21. 2001-02-22. PMID:11050131. |
this stability pattern parallels both the reduced late-phase long-term potentiation in hippocampal slices from r(ab) mice and the amnesia for context fear conditioning seen in r(ab) mice 24 but not 1 hr after training. |
2001-02-22 |
2023-08-12 |
mouse |
| M Ammassari-Teule, E Passino, L Restivo, B de Marsanic. Fear conditioning in C57/BL/6 and DBA/2 mice: variability in nucleus accumbens function according to the strain predisposition to show contextual- or cue-based responding. The European journal of neuroscience. vol 12. issue 12. 2001-02-15. PMID:11122357. |
the contribution of the nucleus accumbens shell, the dorsal hippocampus, and the basolateral amygdala to contextual and explicit cue fear conditioning was assessed in c57bl/6 (c57) and dba/2 (dba) mice showing differences in processing contextual information associated with consistent but non-pathological variations in hippocampal functionality. |
2001-02-15 |
2023-08-12 |
mouse |
| M Ammassari-Teule, E Passino, L Restivo, B de Marsanic. Fear conditioning in C57/BL/6 and DBA/2 mice: variability in nucleus accumbens function according to the strain predisposition to show contextual- or cue-based responding. The European journal of neuroscience. vol 12. issue 12. 2001-02-15. PMID:11122357. |
in c57, both nucleus accumbens and hippocampal lesions impaired acquisition of contextual fear conditioning but paradoxically improved acquisition of cue fear conditioning, whereas amygdala lesions disrupted performance in every task. |
2001-02-15 |
2023-08-12 |
mouse |
| M Ammassari-Teule, E Passino, L Restivo, B de Marsanic. Fear conditioning in C57/BL/6 and DBA/2 mice: variability in nucleus accumbens function according to the strain predisposition to show contextual- or cue-based responding. The European journal of neuroscience. vol 12. issue 12. 2001-02-15. PMID:11122357. |
in dba, nucleus accumbens lesions, like amygdala lesions, impaired acquisition of both contextual and cue fear conditioning, whereas hippocampal lesions did not produce any effect. |
2001-02-15 |
2023-08-12 |
mouse |
| J J Merino, M I Cordero, C Sand. Regulation of hippocampal cell adhesion molecules NCAM and L1 by contextual fear conditioning is dependent upon time and stressor intensity. The European journal of neuroscience. vol 12. issue 9. 2000-11-07. PMID:10998112. |
given that the degree of stress elicited by the training situation is one of the key factors that influence consolidation processes, this study questioned whether training rats under different stressor intensities (0.2, 0.4, or 1 ma shock intensity) in a contextual fear conditioning task might regulate subsequent expression of ncam, psa-ncam and l1 in the hippocampus, as evaluated immediately after testing rats for conditioning at 12 and 24 h after training. |
2000-11-07 |
2023-08-12 |
rat |
| L S Stewart, B E McKa. Acquisition deficit and time-dependent retrograde amnesia for contextual fear conditioning in agmatine-treated rats. Behavioural pharmacology. vol 11. issue 1. 2000-08-24. PMID:10821214. |
pharmacological studies have indicated that acquisition of background contextual cues during pavlovian fear conditioning is dependent upon hippocampal function, whereas early inactivation of the hippocampus after training produces retrograde amnesia. |
2000-08-24 |
2023-08-12 |
human |
| S Malkani, J B Rose. Specific induction of early growth response gene 1 in the lateral nucleus of the amygdala following contextual fear conditioning in rats. Neuroscience. vol 97. issue 4. 2000-07-24. PMID:10842014. |
the increased expression of egr-1 was specifically localized to the lateral nucleus of the amygdala; expression in the hippocampus and cortex was not increased by fear conditioning. |
2000-07-24 |
2023-08-12 |
rat |
| S Malkani, J B Rose. Specific induction of early growth response gene 1 in the lateral nucleus of the amygdala following contextual fear conditioning in rats. Neuroscience. vol 97. issue 4. 2000-07-24. PMID:10842014. |
in contrast, the expression of egr-2, egr-3, and egr-4 messenger rna was not increased in the amygdala, hippocampus or cortex following fear conditioning. |
2000-07-24 |
2023-08-12 |
rat |
| S Malkani, J B Rose. Specific induction of early growth response gene 1 in the lateral nucleus of the amygdala following contextual fear conditioning in rats. Neuroscience. vol 97. issue 4. 2000-07-24. PMID:10842014. |
in addition, following a retention test conducted 24h after fear conditioning, no increases were found in the expression of egr-1 messenger rna expression in the amygdala, hippocampus or cortex. |
2000-07-24 |
2023-08-12 |
rat |
| J C Gewirtz, K A McNish, M Davi. Is the hippocampus necessary for contextual fear conditioning? Behavioural brain research. vol 110. issue 1-2. 2000-06-30. PMID:10802306. |
this view is based primarily on evidence that lesions of the dorsal hippocampus disrupt freezing to contextual cues after fear conditioning. |
2000-06-30 |
2023-08-12 |
rat |
| J Radulovic, A Fischer, U Katerkamp, J Spies. Role of regional neurotransmitter receptors in corticotropin-releasing factor (CRF)-mediated modulation of fear conditioning. Neuropharmacology. vol 39. issue 4. 2000-04-20. PMID:10728892. |
we have demonstrated previously that stimulation of hippocampal corticotropin-releasing factor (crf) receptors enhances, whereas stimulation of crf receptors in the lateral intermediate septum impairs learning, as indicated by fear conditioning. |
2000-04-20 |
2023-08-12 |
Not clear |
| E A Antoniadis, R J McDonal. Amygdala, hippocampus and discriminative fear conditioning to context. Behavioural brain research. vol 108. issue 1. 2000-03-21. PMID:10680753. |
amygdala, hippocampus and discriminative fear conditioning to context. |
2000-03-21 |
2023-08-12 |
rat |
| E A Antoniadis, R J McDonal. Amygdala, hippocampus and discriminative fear conditioning to context. Behavioural brain research. vol 108. issue 1. 2000-03-21. PMID:10680753. |
the proposed view ascribes an equal role in fear conditioning to both the amygdala and the hippocampus. |
2000-03-21 |
2023-08-12 |
rat |
| S G Anagnostaras, S Maren, J R Sage, S Goodrich, M S Fanselo. Scopolamine and Pavlovian fear conditioning in rats: dose-effect analysis. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 21. issue 6. 2000-01-28. PMID:10633479. |
hippocampal lesions produce both acquisition deficits and retrograde amnesia of contextual fear (fear of the place of conditioning), but do not impact fear conditioning to discrete cues (such as a tone). |
2000-01-28 |
2023-08-12 |
rat |
| A Desmedt, R Garcia, R Jaffar. Vasopressin in the lateral septum promotes elemental conditioning to the detriment of contextual fear conditioning in mice. The European journal of neuroscience. vol 11. issue 11. 1999-12-28. PMID:10583480. |
previous experiments using a classical fear conditioning paradigm have provided evidence that the processing of contextual conditional stimuli (css) by the hippocampus would be controlled by the amygdala through a modulation of hippocampal-lateral septal (h-ls) excitability. |
1999-12-28 |
2023-08-12 |
mouse |
| C R Pryce, J Lehmann, J Feldo. Effect of sex on fear conditioning is similar for context and discrete CS in Wistar, Lewis and Fischer rat strains. Pharmacology, biochemistry, and behavior. vol 64. issue 4. 1999-12-21. PMID:10593198. |
these findings have been combined with evidence for greater levels of hippocampal ltp in males in sprague-dawley rats to derive a model of hippocampal-ltp-mediated contextual and not cs, fear conditioning. |
1999-12-21 |
2023-08-12 |
rat |
| R Walz, R Roesler, J Quevedo, I C Rockenbach, O B Amaral, M R Vianna, G Lenz, J H Medina, I Izquierd. Dose-dependent impairment of inhibitory avoidance retention in rats by immediate post-training infusion of a mitogen-activated protein kinase kinase inhibitor into cortical structures. Behavioural brain research. vol 105. issue 2. 1999-12-15. PMID:10563495. |
mapk is activated in and required for both the induction of long-term potentiation (ltp) in hippocampal slices and the acquisition of fear conditioning training in rats. |
1999-12-15 |
2023-08-12 |
rat |
| C D Conrad, J E LeDoux, A M Magariños, B S McEwe. Repeated restraint stress facilitates fear conditioning independently of causing hippocampal CA3 dendritic atrophy. Behavioral neuroscience. vol 113. issue 5. 1999-12-02. PMID:10571474. |
this study investigated whether 21 days of restraint stress (6 hr/day) and the subsequent hippocampal dendritic atrophy would affect fear conditioning, a memory task with hippocampal-dependent and hippocampal-independent components. |
1999-12-02 |
2023-08-12 |
rat |
| C D Conrad, J E LeDoux, A M Magariños, B S McEwe. Repeated restraint stress facilitates fear conditioning independently of causing hippocampal CA3 dendritic atrophy. Behavioral neuroscience. vol 113. issue 5. 1999-12-02. PMID:10571474. |
restraint-stressed rats were injected daily (21 days) with tianeptine (10 mg/kg; to prevent hippocampal atrophy) or vehicle then tested on fear conditioning (days 23-25, with 2 tone-shock pairings) and open field (day 25). |
1999-12-02 |
2023-08-12 |
rat |