| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Gerlai, N Shinsky, A Shih, P Williams, J Winer, M Armanini, B Cairns, J Winslow, W Gao, H S Phillip. Regulation of learning by EphA receptors: a protein targeting study. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 21. 1999-11-19. PMID:10531456. |
we demonstrate that intrahippocampal infusion of an epha antagonist immunoadhesin leads to impaired performance in two behavioral paradigms, t-maze spontaneous alternation and context-dependent fear conditioning, sensitive to hippocampal function, whereas activation of epha by infusion of an agonist immunoadhesin results in enhanced performance on these tasks. |
1999-11-19 |
2023-08-12 |
mouse |
| R G Phillips, J E LeDou. Lesions of the dorsal hippocampal formation interfere with background but not foreground contextual fear conditioning. Learning & memory (Cold Spring Harbor, N.Y.). vol 1. issue 1. 1999-09-29. PMID:10467584. |
these results have implications for understanding both fear conditioning and hippocampal function. |
1999-09-29 |
2023-08-12 |
Not clear |
| M Ema, S Ikegami, T Hosoya, J Mimura, H Ohtani, K Nakao, K Inokuchi, M Katsuki, Y Fujii-Kuriyam. Mild impairment of learning and memory in mice overexpressing the mSim2 gene located on chromosome 16: an animal model of Down's syndrome. Human molecular genetics. vol 8. issue 8. 1999-09-14. PMID:10400987. |
here we describe that msim2 mrna is expressed in hippocampus and amygdala of adult mice, and that while mice overexpressing msim2 under the control of the beta-actin promoter are viable and fertile and have superficially normal skeletal, brain and heart structures, they exhibit a moderate defect in context-dependent fear conditioning and a mild defect in the morris water maze test. |
1999-09-14 |
2023-08-12 |
mouse |
| P Gisquet-Verrier, G Dutrieux, P Richer, V Doyèr. Effects of lesions to the hippocampus on contextual fear: evidence for a disruption of freezing and avoidance behavior but not context conditioning. Behavioral neuroscience. vol 113. issue 3. 1999-09-14. PMID:10443778. |
the effects of ibotenic lesions of the hippocampus on conditioning to contextual cues during classical fear conditioning in rats were evaluated by (a) the amount of freezing elicited by contextual cues and (b) the relative avoidance of a shock compartment. |
1999-09-14 |
2023-08-12 |
rat |
| J Ferbinteanu, R M Holsinger, R J McDonal. Lesions of the medial or lateral perforant path have different effects on hippocampal contributions to place learning and on fear conditioning to context. Behavioural brain research. vol 101. issue 1. 1999-08-05. PMID:10342401. |
lesions of the medial or lateral perforant path have different effects on hippocampal contributions to place learning and on fear conditioning to context. |
1999-08-05 |
2023-08-12 |
rat |
| R J Frohardt, F A Guarraci, S L Youn. Intrahippocampal infusions of a metabotropic glutamate receptor antagonist block the memory of context-specific but not tone-specific conditioned fear. Behavioral neuroscience. vol 113. issue 1. 1999-07-16. PMID:10197922. |
the mglur antagonist (r, s)-alpha-methyl-4-carboxyphenylglycine (mcpg) was infused into the hippocampus 30 min before fear conditioning, and freezing was measured during both acquisition and retention tests. |
1999-07-16 |
2023-08-12 |
rat |
| J A Oler, E J Marku. Age-related deficits on the radial maze and in fear conditioning: hippocampal processing and consolidation. Hippocampus. vol 8. issue 4. 1999-05-18. PMID:9744425. |
age-related deficits on the radial maze and in fear conditioning: hippocampal processing and consolidation. |
1999-05-18 |
2023-08-12 |
rat |
| J A Oler, E J Marku. Age-related deficits on the radial maze and in fear conditioning: hippocampal processing and consolidation. Hippocampus. vol 8. issue 4. 1999-05-18. PMID:9744425. |
it has previously been shown on the fear conditioning paradigm that the hippocampus is involved in retention of the aversive context for approximately 28 days. |
1999-05-18 |
2023-08-12 |
rat |
| M D McEchron, H Bouwmeester, W Tseng, C Weiss, J F Disterhof. Hippocampectomy disrupts auditory trace fear conditioning and contextual fear conditioning in the rat. Hippocampus. vol 8. issue 6. 1999-03-22. PMID:9882021. |
animals in the hipp group did not show conditioned fear responses to the cs alone, nor did a pseudoconditioning group (n = 7) that was trained with unpaired css and uss. |
1999-03-22 |
2023-08-12 |
rat |
| M D McEchron, H Bouwmeester, W Tseng, C Weiss, J F Disterhof. Hippocampectomy disrupts auditory trace fear conditioning and contextual fear conditioning in the rat. Hippocampus. vol 8. issue 6. 1999-03-22. PMID:9882021. |
furthermore, all groups except the hipp group showed conditioned fear responses to the original context in which they received shock uss. |
1999-03-22 |
2023-08-12 |
rat |
| S G Anagnostaras, S Maren, M S Fanselo. Temporally graded retrograde amnesia of contextual fear after hippocampal damage in rats: within-subjects examination. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 3. 1999-02-25. PMID:9920672. |
we have shown previously that electrolytic lesions of the dorsal hippocampus (dh) produce a severe deficit in contextual fear if made 1 d, but not 28 d, after fear conditioning (). |
1999-02-25 |
2023-08-12 |
rat |
| R Gerla. Contextual learning and cue association in fear conditioning in mice: a strain comparison and a lesion study. Behavioural brain research. vol 95. issue 2. 1999-01-29. PMID:9806439. |
fear conditioning with electric shock (unconditioned stimulus, us) paired with tone cue (conditioned stimulus, cs) has been extensively applied in recent molecular neurobiological analysis of hippocampal dysfunction in mice because the context-dependent test phase of this learning paradigm is claimed to detect hippocampal impairment in a specific manner, whereas the cue-dependent test serves as a control situation independent of hippocampal function. |
1999-01-29 |
2023-08-12 |
mouse |
| R Gerla. Contextual learning and cue association in fear conditioning in mice: a strain comparison and a lesion study. Behavioural brain research. vol 95. issue 2. 1999-01-29. PMID:9806439. |
therefore, i investigated how hippocampal ibotenic acid lesion affects conditioned fear in mice. |
1999-01-29 |
2023-08-12 |
mouse |
| R Gerla. A new continuous alternation task in T-maze detects hippocampal dysfunction in mice. A strain comparison and lesion study. Behavioural brain research. vol 95. issue 1. 1998-12-29. PMID:9754881. |
in this paper a novel behavioral test procedure is introduced, a modified t-maze continuous alternation task (t-cat), that may serve as a simple, automatable, and quick test of hippocampal function in addition to the frequently applied water maze and fear conditioning paradigms. |
1998-12-29 |
2023-08-12 |
mouse |
| S G Anagnostaras, S Maren, J P DeCola, N I Lane, G D Gale, B A Schlinger, M S Fanselo. Testicular hormones do not regulate sexually dimorphic Pavlovian fear conditioning or perforant-path long-term potentiation in adult male rats. Behavioural brain research. vol 92. issue 1. 1998-06-26. PMID:9588680. |
we recently reported that pavlovian fear conditioning and hippocampal perforant-path long-term potentiation (ltp) are sexually dimorphic in rats. |
1998-06-26 |
2023-08-12 |
rat |
| S G Anagnostaras, S Maren, J P DeCola, N I Lane, G D Gale, B A Schlinger, M S Fanselo. Testicular hormones do not regulate sexually dimorphic Pavlovian fear conditioning or perforant-path long-term potentiation in adult male rats. Behavioural brain research. vol 92. issue 1. 1998-06-26. PMID:9588680. |
that is, in every respect, castrated male rats were similar to intact male rats in pavlovian fear conditioning and hippocampal ltp. |
1998-06-26 |
2023-08-12 |
rat |
| S Milanovic, J Radulovic, O Laban, O Stiedl, F Henn, J Spies. Production of the Fos protein after contextual fear conditioning of C57BL/6N mice. Brain research. vol 784. issue 1-2. 1998-04-30. PMID:9518543. |
the results demonstrated that simultaneous fos production in the hippocampus, central and medial nuclei of amygdala and somatosensory parietal cortex closely paralleled the ability of mice to acquire conditioned fear. |
1998-04-30 |
2023-08-12 |
mouse |
| E A Phelps, K S LaBar, D D Spence. Memory for emotional words following unilateral temporal lobectomy. Brain and cognition. vol 35. issue 1. 1998-01-20. PMID:9339304. |
we recently reported that patients who had received unilateral temporal lobectomy, including the amygdala and hippocampus, show impaired acquisition in a fear conditioning task (labar, ledoux, spencer, & phelps, 1995), indicating a deficit in emotional memory. |
1998-01-20 |
2023-08-12 |
human |
| G Winocu. Hippocampal lesions alter conditioning to conditional and contextual stimuli. Behavioural brain research. vol 88. issue 2. 1998-01-14. PMID:9404631. |
the control of conditioned fear behaviour by a conditional stimulus (cs) and contextual stimuli (cxt) was compared in rats with lesions to the hippocampus (hpc) or neocortex (co), and operated controls (oc). |
1998-01-14 |
2023-08-12 |
rat |
| G Winocu. Hippocampal lesions alter conditioning to conditional and contextual stimuli. Behavioural brain research. vol 88. issue 2. 1998-01-14. PMID:9404631. |
groups did not differ in acquiring the conditioned fear response, as measured in the cs + con test but, in both experiments, hippocampal (hpc) groups exhibited more conditioned fear behaviour than controls in the cxt-only and cs-only conditions. |
1998-01-14 |
2023-08-12 |
rat |