| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lindsay C Reese, Fernanda Laezza, Randall Woltjer, Giulio Taglialatel. Dysregulated phosphorylation of Ca(2+) /calmodulin-dependent protein kinase II-α in the hippocampus of subjects with mild cognitive impairment and Alzheimer's disease. Journal of neurochemistry. vol 119. issue 4. 2011-12-23. PMID:21883216. |
treatment with oligomeric aβ replicated the observed phenotype in mice and resulted in a loss of p(thr286)camkii from synaptic spines of primary hippocampal neurons. |
2011-12-23 |
2023-08-12 |
mouse |
| Richard M Gustin, Brian C Shonesy, Stacey L Robinson, Tyler J Rentz, Anthony J Baucum, Nidhi Jalan-Sakrikar, Danny G Winder, Gregg D Stanwood, Roger J Colbra. Loss of Thr286 phosphorylation disrupts synaptic CaMKIIα targeting, NMDAR activity and behavior in pre-adolescent mice. Molecular and cellular neurosciences. vol 47. issue 4. 2011-12-06. PMID:21627991. |
total levels of glua1 ampa-glutamate receptor subunits and phosphorylation of glua1 at the camkii site (ser831) in synaptic fractions were unaltered, as were the frequency and amplitude of ampar-mediated spontaneous excitatory postsynaptic currents at hippocampal ca3-ca1 synapses. |
2011-12-06 |
2023-08-12 |
mouse |
| Hae Young Lee, Byoung-Chul Yang, Eun-Shil Lee, Jong Ii Chung, Phil Ok Koh, Moon Seok Park, Myeong Ok Ki. Modulation by the GABA(B) receptor siRNA of ethanol-mediated PKA-α, CaMKII, and p-CREB intracellular signaling in prenatal rat hippocampal neurons. Anatomy & cell biology. vol 44. issue 3. 2011-11-10. PMID:22025973. |
modulation by the gaba(b) receptor sirna of ethanol-mediated pka-α, camkii, and p-creb intracellular signaling in prenatal rat hippocampal neurons. |
2011-11-10 |
2023-08-12 |
rat |
| Hae Young Lee, Byoung-Chul Yang, Eun-Shil Lee, Jong Ii Chung, Phil Ok Koh, Moon Seok Park, Myeong Ok Ki. Modulation by the GABA(B) receptor siRNA of ethanol-mediated PKA-α, CaMKII, and p-CREB intracellular signaling in prenatal rat hippocampal neurons. Anatomy & cell biology. vol 44. issue 3. 2011-11-10. PMID:22025973. |
et increased gaba(b1)r protein levels, but decreased protein kinase a-α (pka-α), calcium/calmodulin-dependent protein kinase ii (camkii) and phosphorylation of camp-response element binding protein (p-creb), in cultured hippocampal neurons harvested at gestation day 17.5. |
2011-11-10 |
2023-08-12 |
rat |
| Jing Dong, Wanyang Liu, Yi Wang, Yi Hou, Hongde Xu, Jian Gong, Qi Xi, Jie Che. Developmental iodine deficiency and hypothyroidism impair spatial memory in adolescent rat hippocampus: involvement of CaMKII, calmodulin and calcineurin. Neurotoxicity research. vol 19. issue 1. 2011-11-08. PMID:19997993. |
developmental iodine deficiency and hypothyroidism impair spatial memory in adolescent rat hippocampus: involvement of camkii, calmodulin and calcineurin. |
2011-11-08 |
2023-08-12 |
rat |
| Jing Dong, Wanyang Liu, Yi Wang, Yi Hou, Hongde Xu, Jian Gong, Qi Xi, Jie Che. Developmental iodine deficiency and hypothyroidism impair spatial memory in adolescent rat hippocampus: involvement of CaMKII, calmodulin and calcineurin. Neurotoxicity research. vol 19. issue 1. 2011-11-08. PMID:19997993. |
here, we show that hippocampal calcium/calmodulin-dependent protein kinase ii (camkii), calmodulin and calcineurin are implicated in the impaired spatial memory in adolescent rats following developmental id and hypothyroidism. |
2011-11-08 |
2023-08-12 |
rat |
| Jing Dong, Wanyang Liu, Yi Wang, Yi Hou, Hongde Xu, Jian Gong, Qi Xi, Jie Che. Developmental iodine deficiency and hypothyroidism impair spatial memory in adolescent rat hippocampus: involvement of CaMKII, calmodulin and calcineurin. Neurotoxicity research. vol 19. issue 1. 2011-11-08. PMID:19997993. |
total and phosphorylated camkii, calmodulin, and calcineurin in the hippocampus were detected with both the immunohistochemistry and western blotting. |
2011-11-08 |
2023-08-12 |
rat |
| Jing Dong, Wanyang Liu, Yi Wang, Yi Hou, Hongde Xu, Jian Gong, Qi Xi, Jie Che. Developmental iodine deficiency and hypothyroidism impair spatial memory in adolescent rat hippocampus: involvement of CaMKII, calmodulin and calcineurin. Neurotoxicity research. vol 19. issue 1. 2011-11-08. PMID:19997993. |
data indicate that hippocampal camkii, calmodulin, and calcineurin are involved in the impaired spatial memory induced by developmental id and hypothyroidism. |
2011-11-08 |
2023-08-12 |
rat |
| Nils Z Borgesius, Geeske M van Woerden, Gabrielle H S Buitendijk, Nanda Keijzer, Dick Jaarsma, Casper C Hoogenraad, Ype Elgersm. βCaMKII plays a nonenzymatic role in hippocampal synaptic plasticity and learning by targeting αCaMKII to synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 28. 2011-09-12. PMID:21752990. |
together, our data provide compelling support for a model of camkii function in which αcamkii and βcamkii act in concert, but with distinct functions, to regulate hippocampal synaptic plasticity and learning. |
2011-09-12 |
2023-08-12 |
mouse |
| Magdalena Sanhueza, German Fernandez-Villalobos, Ivar S Stein, Gyulnara Kasumova, Peng Zhang, K Ulrich Bayer, Nikolai Otmakhov, Johannes W Hell, John Lisma. Role of the CaMKII/NMDA receptor complex in the maintenance of synaptic strength. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 25. 2011-09-02. PMID:21697368. |
we used the cn class of peptides that inhibit camkii binding to the nr2b subunit in vitro to test this prediction in rat hippocampal slices. |
2011-09-02 |
2023-08-12 |
rat |
| Anders S Kristensen, Meagan A Jenkins, Tue G Banke, Arne Schousboe, Yuichi Makino, Richard C Johnson, Richard Huganir, Stephen F Trayneli. Mechanism of Ca2+/calmodulin-dependent kinase II regulation of AMPA receptor gating. Nature neuroscience. vol 14. issue 6. 2011-08-17. PMID:21516102. |
we show that camkii increases the conductance of native heteromeric ampa receptors in mouse hippocampal neurons through phosphorylation of ser831. |
2011-08-17 |
2023-08-12 |
mouse |
| Shigeki Moriguchi, Yui Yamamoto, Tatsuya Ikuno, Kohji Fukunag. Sigma-1 receptor stimulation by dehydroepiandrosterone ameliorates cognitive impairment through activation of CaM kinase II, protein kinase C and extracellular signal-regulated kinase in olfactory bulbectomized mice. Journal of neurochemistry. vol 117. issue 5. 2011-06-30. PMID:21434925. |
we have previously reported that calcium/calmodulin-dependent protein kinase ii (camkii), protein kinase c (pkc) and extracellular signal-regulated kinase (erk) were impaired in obx mouse hippocampus. |
2011-06-30 |
2023-08-12 |
mouse |
| B Xing, H Kong, X Meng, S G Wei, M Xu, S B L. Dopamine D1 but not D3 receptor is critical for spatial learning and related signaling in the hippocampus. Neuroscience. vol 169. issue 4. 2011-04-18. PMID:20600656. |
furthermore, activation of the nmda receptor r1 subunit (nr1), camkii and creb in the hippocampus is also significantly lower in d(1) receptor mutant mice compared to wild-type and d(3) receptor mutant mice. |
2011-04-18 |
2023-08-12 |
mouse |
| Ian M Brooks, Steven J Tavali. Ca2+/calmodulin-dependent protein kinase II inhibitors disrupt AKAP79-dependent PKC signaling to GluA1 AMPA receptors. The Journal of biological chemistry. vol 286. issue 8. 2011-04-14. PMID:21156788. |
in the absence of camkii activation, complementary cellular studies revealed that kn-62 and kn-93, but not kn-92 or camkiintide, inhibited pkc-mediated phosphorylation of glua1 in hippocampal neurons as well as akap79-dependent pkc-mediated augmentation of recombinant glua1 currents. |
2011-04-14 |
2023-08-12 |
Not clear |
| Vanessa J Appleby, Sonia A L Corrêa, Joshua K Duckworth, Joanne E Nash, Jacques Noël, Stephen M Fitzjohn, Graham L Collingridge, Elek Molná. LTP in hippocampal neurons is associated with a CaMKII-mediated increase in GluA1 surface expression. Journal of neurochemistry. vol 116. issue 4. 2011-03-22. PMID:21143596. |
camkii activation is therefore an important factor in the activity-dependent recruitment of native glua1 subunit-containing alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptors to the cell surface of hippocampal neurons. |
2011-03-22 |
2023-08-12 |
Not clear |
| Yi Wang, Yi Hou, Jing Dong, Hongde Xu, Jian Gong, Jie Che. Developmental iodine deficiency and hypothyroidism reduce phosphorylation of calcium/calmodulin-dependent kinase II in the rat entorhinal cortex. Biological trace element research. vol 137. issue 3. 2011-01-31. PMID:20054663. |
recent studies have shown that hypothyroidism alters phosphorylation of camkii in hippocampus or even in sympathetic ganglia of rats. |
2011-01-31 |
2023-08-12 |
rat |
| Yan Zeng, Danyun Zhao, Cui-Wei Xi. Neurotrophins enhance CaMKII activity and rescue amyloid-β-induced deficits in hippocampal synaptic plasticity. Journal of Alzheimer's disease : JAD. vol 21. issue 3. 2011-01-18. PMID:20634586. |
neurotrophins enhance camkii activity and rescue amyloid-β-induced deficits in hippocampal synaptic plasticity. |
2011-01-18 |
2023-08-12 |
rat |
| Jing Dong, Wanyang Liu, Yi Wang, Qi Xi, Jie Che. Hypothyroidism following developmental iodine deficiency reduces hippocampal neurogranin, CaMK II and calmodulin and elevates calcineurin in lactational rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 28. issue 7. 2011-01-13. PMID:20654708. |
here, we show that hippocampal neurogranin, calcium/calmodulin dependent protein kinase ii (camkii), calmodulin (cam) and calcineurin (can) are implicated in the brain impairment in lactational rat hippocampus following developmental id and hypothyroidism. |
2011-01-13 |
2023-08-12 |
rat |
| Jing Dong, Wanyang Liu, Yi Wang, Qi Xi, Jie Che. Hypothyroidism following developmental iodine deficiency reduces hippocampal neurogranin, CaMK II and calmodulin and elevates calcineurin in lactational rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 28. issue 7. 2011-01-13. PMID:20654708. |
then, the neurogranin, camkii, cam and can in the hippocampus were detected with immunohistochemistry and western blotting on pn14 and pn21. |
2011-01-13 |
2023-08-12 |
rat |
| Jing Dong, Wanyang Liu, Yi Wang, Qi Xi, Jie Che. Hypothyroidism following developmental iodine deficiency reduces hippocampal neurogranin, CaMK II and calmodulin and elevates calcineurin in lactational rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 28. issue 7. 2011-01-13. PMID:20654708. |
data indicate that, in lactational rats, hippocampal neurogranin, camkii, cam and can are involved in the brain impairment by developmental id and hypothyroidism. |
2011-01-13 |
2023-08-12 |
rat |