| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Revaz Solomonia, Ekaterine Mikautadze, Maia Nozadze, Nino Kuchiashvili, Eka Lepsveridze, Tamar Kiguradz. Myo-inositol treatment prevents biochemical changes triggered by kainate-induced status epilepticus. Neuroscience letters. vol 468. issue 3. 2010-04-06. PMID:19914343. |
changes in the amounts of following proteins were studied in the hippocampus and neocortex of rats: glur1 subunit of glutamate receptors, calcium/calmodulin-dependent protein kinase ii (camkii), and heat shock protein 90. |
2010-04-06 |
2023-08-12 |
rat |
| Revaz Solomonia, Ekaterine Mikautadze, Maia Nozadze, Nino Kuchiashvili, Eka Lepsveridze, Tamar Kiguradz. Myo-inositol treatment prevents biochemical changes triggered by kainate-induced status epilepticus. Neuroscience letters. vol 468. issue 3. 2010-04-06. PMID:19914343. |
however on 28th day of experiment the amounts of glur1 and camkii were strongly reduced in the hippocampus of ka treated animals but mi significantly halted this reduction. |
2010-04-06 |
2023-08-12 |
rat |
| Mauro Racaniello, Alessio Cardinale, Cristiana Mollinari, Margherita D'Antuono, Giovanna De Chiara, Virginia Tancredi, Daniela Merl. Phosphorylation changes of CaMKII, ERK1/2, PKB/Akt kinases and CREB activation during early long-term potentiation at Schaffer collateral-CA1 mouse hippocampal synapses. Neurochemical research. vol 35. issue 2. 2010-03-23. PMID:19731018. |
phosphorylation changes of camkii, erk1/2, pkb/akt kinases and creb activation during early long-term potentiation at schaffer collateral-ca1 mouse hippocampal synapses. |
2010-03-23 |
2023-08-12 |
mouse |
| Anu Aonurm-Helm, Vladimir Berezin, Elisabeth Bock, Alexander Zharkovsk. NCAM-mimetic, FGL peptide, restores disrupted fibroblast growth factor receptor (FGFR) phosphorylation and FGFR mediated signaling in neural cell adhesion molecule (NCAM)-deficient mice. Brain research. vol 1309. 2010-02-26. PMID:19909731. |
therefore we compared the levels of phosphorylation of fgfr1, src kinase fyn, raf1 kinase, map kinases, akt kinase and calcium/calmodulin-dependent kinases ii and iv (camkii and camkiv) in the hippocampus of ncam knockout mice to their wild-type littermates. |
2010-02-26 |
2023-08-12 |
mouse |
| M Rapanelli, L R Frick, B S Zanutt. Differential gene expression in the rat hippocampus during learning of an operant conditioning task. Neuroscience. vol 163. issue 4. 2010-02-12. PMID:19632308. |
in this study, we measured mrna expression in the hippocampus by real time (rt)-pcr mrna levels of bdnf, creb, synapsin i, camkii, arc, c-jun and c-fos, during learning and operant conditioning task. |
2010-02-12 |
2023-08-12 |
rat |
| Yui Yamamoto, Norifumi Shioda, Feng Han, Shigeki Moriguchi, Akira Nakajima, Akihito Yokosuka, Yoshihiro Mimaki, Yutaka Sashida, Tohru Yamakuni, Yasushi Ohizumi, Kohji Fukunag. Nobiletin improves brain ischemia-induced learning and memory deficits through stimulation of CaMKII and CREB phosphorylation. Brain research. vol 1295. 2009-12-16. PMID:19646972. |
consistent with the restored camkii and erk phosphorylation, an electrophysiological study showed that the impaired hippocampal long-term potentiation (ltp) observed in the 5-min ischemic mice was significantly improved by the nobiletin treatment. |
2009-12-16 |
2023-08-12 |
mouse |
| Wiktor Bilecki, Agnieszka Wawrzczak-Bargiela, Ryszard Przewłock. Regulation of kinesin light chain 1 level correlates with the development of morphine reward in the mouse brain. The European journal of neuroscience. vol 30. issue 6. 2009-11-17. PMID:19735294. |
in the cortex, hippocampus and amygdala, klc1 co-localized with calcium/calmodulin-dependent protein kinase ii (camkii), suggesting that klc1 was present in the cell bodies and dendrites of pyramidal neurons. |
2009-11-17 |
2023-08-12 |
mouse |
| T A Savina, T G Shchipakina, O V Godukhi. [Single audiogenic seizure promotes the increased levels of calcineurin and Ca(2+)-calmodulin-dependent protein kinase II in the rat brain]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 95. issue 8. 2009-11-12. PMID:19803210. |
immunoblots of hippocampal and cortical (from sensomotor area) homogenates reacted with monoclonal antibodies to neurospecific alpha-subunit camkii showed an increased presence of this protein in seizured animals in comparison with naive controls. |
2009-11-12 |
2023-08-12 |
rat |
| T A Savina, T G Shchipakina, O V Godukhi. [Single audiogenic seizure promotes the increased levels of calcineurin and Ca(2+)-calmodulin-dependent protein kinase II in the rat brain]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 95. issue 8. 2009-11-12. PMID:19803210. |
additionally, studies of camkii activity revealed that the total enzyme activity from hippocampus and cortex of seizured rats was increased as compared with controls. |
2009-11-12 |
2023-08-12 |
rat |
| A P Raval, I Saul, K R Dave, R A DeFazio, M A Perez-Pinzon, H Bramlet. Pretreatment with a single estradiol-17beta bolus activates cyclic-AMP response element binding protein and protects CA1 neurons against global cerebral ischemia. Neuroscience. vol 160. issue 2. 2009-10-21. PMID:19272413. |
a similar phosphorylation pattern was also observed for mitogen-activated protein kinase (mapk) and calcium-calmodulin-dependent protein kinase (camkii) in hippocampus. |
2009-10-21 |
2023-08-12 |
rat |
| Henrik Viber. Exposure to polybrominated diphenyl ethers 203 and 206 during the neonatal brain growth spurt affects proteins important for normal neurodevelopment in mice. Toxicological sciences : an official journal of the Society of Toxicology. vol 109. issue 2. 2009-09-03. PMID:19380496. |
the protein analysis showed that camkii and synaptophysin increased significantly in the hippocampus, but not in the cerebral cortex, after neonatal exposure to pbde 203 or 206. |
2009-09-03 |
2023-08-12 |
mouse |
| Takeshi Kanno, Takahiro Yaguchi, Tetsu Nagata, Akito Tanaka, Tomoyuki Nishizak. DCP-LA stimulates AMPA receptor exocytosis through CaMKII activation due to PP-1 inhibition. Journal of cellular physiology. vol 221. issue 1. 2009-08-28. PMID:19492412. |
dcp-la induced a transient huge facilitation of synaptic transmission monitored from the ca1 region of rat hippocampal slices, which was largely inhibited by the camkii inhibitor kn-93. |
2009-08-28 |
2023-08-12 |
rat |
| Takeshi Kanno, Takahiro Yaguchi, Tetsu Nagata, Akito Tanaka, Tomoyuki Nishizak. DCP-LA stimulates AMPA receptor exocytosis through CaMKII activation due to PP-1 inhibition. Journal of cellular physiology. vol 221. issue 1. 2009-08-28. PMID:19492412. |
dcp-la, thus, appears to activate camkii through pp-1 inhibition, that stimulates ampa receptor exocytosis to increase expression of the receptors on the plasma membrane, responsible for potentiate ampa receptor responses and facilitation of hippocampal synaptic transmission. |
2009-08-28 |
2023-08-12 |
rat |
| Xiang-ming Zha, Michael E Dailey, Steven H Gree. Role of Ca2+/calmodulin-dependent protein kinase II in dendritic spine remodeling during epileptiform activity in vitro. Journal of neuroscience research. vol 87. issue 9. 2009-08-14. PMID:19235894. |
because camkii has been implicated in synaptogenesis and synaptic plasticity, we investigated the role of camkii in the effects of ea on spines, using rat hippocampal slice cultures. |
2009-08-14 |
2023-08-12 |
rat |
| Eiki Takahashi, Kimie Niimi, Chitoshi Itakur. Enhanced CaMKII activity and spatial cognitive function in SAMP6 mice. Behavioral neuroscience. vol 123. issue 3. 2009-08-13. PMID:19485558. |
the levels of thr286 and ser831 phosphorylation of camkii and ampa receptor subunit glutamate receptor 1 (camkii substrate), respectively, were increased in hippocampus of samp6 compared with samr1. |
2009-08-13 |
2023-08-12 |
mouse |
| Niclas Johansson, Per Eriksson, Henrik Viber. Neonatal exposure to PFOS and PFOA in mice results in changes in proteins which are important for neuronal growth and synaptogenesis in the developing brain. Toxicological sciences : an official journal of the Society of Toxicology. vol 108. issue 2. 2009-06-15. PMID:19211617. |
the present study shows that a single oral dose of either 21 micromol pfos or pfoa/kg body weight (11.3 or 8.70 mg), given directly to the neonatal mice on postnatal day 10, significantly increased the levels of camkii, gap-43, and synaptophysin in the hippocampus of the neonatal mouse. |
2009-06-15 |
2023-08-12 |
mouse |
| Xu Cui, Junfa Li, Tianzuo Li, Fang Ji, Xiangning Bu, Nan Zhang, Bingxi Zhan. Propofol and ketamine-induced anesthetic depth-dependent decrease of CaMKII phosphorylation levels in rat hippocampus and cortex. Journal of neurosurgical anesthesiology. vol 21. issue 2. 2009-05-21. PMID:19295394. |
propofol and ketamine-induced anesthetic depth-dependent decrease of camkii phosphorylation levels in rat hippocampus and cortex. |
2009-05-21 |
2023-08-12 |
rat |
| Xu Cui, Junfa Li, Tianzuo Li, Fang Ji, Xiangning Bu, Nan Zhang, Bingxi Zhan. Propofol and ketamine-induced anesthetic depth-dependent decrease of CaMKII phosphorylation levels in rat hippocampus and cortex. Journal of neurosurgical anesthesiology. vol 21. issue 2. 2009-05-21. PMID:19295394. |
we found that both propofol and ketamine could induce a decrease of p-camkii, not camkii total protein, in an anesthetic depth-dependent manner, whereas only ketamine caused a dose (50, 100, and 150 mg/kg)-dependent depression of p-camkii in hippocampus and frontal cortex of rats after intraperitoneal injections for 30 minutes. |
2009-05-21 |
2023-08-12 |
rat |
| Pei Wang, Wei-Ping Wang, Sun-Zhang, Hai-Xiang Wang, Yan-Lou, Yue-Hui Fa. Impaired spatial learning related with decreased expression of calcium/calmodulin-dependent protein kinase IIalpha and cAMP-response element binding protein in the pentylenetetrazol-kindled rats. Brain research. vol 1238. 2009-02-09. PMID:18710651. |
intracellular ca(2+) plays an important role in regulating many cellular functions including learning and memory, this experiment was therefore conducted, in which, we observed the behaviors of chronic epileptic rats kindled by pentylenetetrazol (ptz) through morris water maze (mwm), examined the concentration of intracellular free calcium ([ca(2+)](i)) with flow cytometry, and tested the expression of calcium/calmodulin-dependent protein kinase iialpha (camkii(alpha)) and camp-response element binding protein (creb) in hippocampus of those rats using western blot and reverse transcription-polymerase chain reaction (rt-pcr). |
2009-02-09 |
2023-08-12 |
rat |
| Pei Wang, Wei-Ping Wang, Sun-Zhang, Hai-Xiang Wang, Yan-Lou, Yue-Hui Fa. Impaired spatial learning related with decreased expression of calcium/calmodulin-dependent protein kinase IIalpha and cAMP-response element binding protein in the pentylenetetrazol-kindled rats. Brain research. vol 1238. 2009-02-09. PMID:18710651. |
we concluded that ca(2+) influx, camkii(alpha) and creb expression levels in hippocampus of chronic epileptic rats may be related with their impaired spatial learning and memory. |
2009-02-09 |
2023-08-12 |
rat |