| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sukumar Pal, Amy P Schmidt, Ellena M Peterson, Carole L Wilson, Luis M de la Maz. Role of matrix metalloproteinase-7 in the modulation of a Chlamydia trachomatis infection. Immunology. vol 117. issue 2. 2006-04-06. PMID:16423057. |
to determine the role of matrix metalloproteinase-7 (mmp-7) in the pathogenesis of chlamydial infection, c57bl/6 wild-type (wt) and mmp-7 knockout (ko) mice were infected intravaginally with chlamydia trachomatis mouse pneumonitis (mopn). |
2006-04-06 |
2023-08-12 |
mouse |
| M Goldberg, D Septier, O Rapoport, R V Iozzo, M F Young, L G Amey. Targeted disruption of two small leucine-rich proteoglycans, biglycan and decorin, excerpts divergent effects on enamel and dentin formation. Calcified tissue international. vol 77. issue 5. 2005-12-20. PMID:16283572. |
dentin matrix protein-1 (dmp-1), bone sialoprotein (bsp) and osteopontin (opn) were upregulated in bgn ko and downregulated in the dcn ko. |
2005-12-20 |
2023-08-12 |
mouse |
| Carla Iacobini, Giovanna Oddi, Stefano Menini, Lorena Amadio, Carlo Ricci, Clelia Di Pippo, Mariella Sorcini, Flavia Pricci, Francesco Pugliese, Giuseppe Puglies. Development of age-dependent glomerular lesions in galectin-3/AGE-receptor-3 knockout mice. American journal of physiology. Renal physiology. vol 289. issue 3. 2005-09-27. PMID:15870382. |
ko mice showed significantly more pronounced age-dependent increases in proteinuria, albuminuria, glomerular sclerosis, and glomerular and mesangial areas, starting at 18 mo, as well as renal extracellular matrix mrna and protein expression, starting at 12 mo vs. age-matched wt mice. |
2005-09-27 |
2023-08-12 |
mouse |
| Jordi Esparza, Meghan Kruse, Janet Lee, Michael Michaud, Joseph A Madr. MMP-2 null mice exhibit an early onset and severe experimental autoimmune encephalomyelitis due to an increase in MMP-9 expression and activity. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 18. issue 14. 2005-05-17. PMID:15522913. |
to better elucidate the roles of this matrix metalloproteinase in the development and progression of experimental autoimmune encephalomyelitis, we used mmp-2-deficient (ko) mice. |
2005-05-17 |
2023-08-12 |
mouse |
| Milla Koistinaho, Tarja M Malm, Mikko I Kettunen, Gundars Goldsteins, Sofie Starckx, Risto A Kauppinen, Ghislain Opdenakker, Jari Koistinah. Minocycline protects against permanent cerebral ischemia in wild type but not in matrix metalloprotease-9-deficient mice. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 25. issue 4. 2005-05-03. PMID:15674236. |
because minocycline inhibits matrix metalloprotease-9 (mmp-9), we also compared minocycline's protective effect in wild type (wt) and mmp-9 knock-out (ko) mice. |
2005-05-03 |
2023-08-12 |
mouse |
| Philippe Bonniaud, Martin Kolb, Tom Galt, Jennifer Robertson, Clinton Robbins, Martin Stampfli, Carol Lavery, Peter J Margetts, Anita B Roberts, Jack Gauldi. Smad3 null mice develop airspace enlargement and are resistant to TGF-beta-mediated pulmonary fibrosis. Journal of immunology (Baltimore, Md. : 1950). vol 173. issue 3. 2004-11-02. PMID:15265946. |
we show that smad3 null mice (knockout (ko)) develop progressive age-related increases in the size of alveolar spaces, associated with high spontaneous presence of matrix metalloproteinases (mmp-9 and mmp-12) in the lung. |
2004-11-02 |
2023-08-12 |
mouse |
| Philippe Bonniaud, Martin Kolb, Tom Galt, Jennifer Robertson, Clinton Robbins, Martin Stampfli, Carol Lavery, Peter J Margetts, Anita B Roberts, Jack Gauldi. Smad3 null mice develop airspace enlargement and are resistant to TGF-beta-mediated pulmonary fibrosis. Journal of immunology (Baltimore, Md. : 1950). vol 173. issue 3. 2004-11-02. PMID:15265946. |
significantly higher levels of matrix components (procollagen 3a1, connective tissue growth factor) and antiproteinases (plasminogen activator inhibitor-1, tissue inhibitor of metalloproteinase-1) were detected in wild-type lungs 4 days after tgf-beta 1 administration, while no such changes were seen in ko lungs. |
2004-11-02 |
2023-08-12 |
mouse |
| Leah C Byrne, Zhongjun Zhou, Karl Tryggvason, Tomas Hökfelt, Sergueï O Fetisso. Altered NPY and AgRP in membrane type-1 matrix metalloproteinase-deficient mice. Neuroreport. vol 15. issue 3. 2004-05-20. PMID:15094525. |
membrane-type-1 matrix metalloproteinase (mt1-mmp) knockout (ko) mice fail to gain weight and die 3-4 weeks after birth. |
2004-05-20 |
2023-08-12 |
mouse |
| Bing-Qiao Zhao, Yasuhiko Ikeda, Hayato Ihara, Tetsumei Urano, WenYing Fan, Sumiko Mikawa, Yasuhiro Suzuki, Kazunao Kondo, Kohji Sato, Nobuo Nagai, Kazuo Umemur. Essential role of endogenous tissue plasminogen activator through matrix metalloproteinase 9 induction and expression on heparin-produced cerebral hemorrhage after cerebral ischemia in mice. Blood. vol 103. issue 7. 2004-05-11. PMID:14630814. |
we also observed an exacerbation of matrix metalloproteinase (mmp) 9 expression at the mrna level and its conversion to an active form after heparin administration in the ischemic hemisphere in wt mice but not in tpa ko mice. |
2004-05-11 |
2023-08-12 |
mouse |
| Joel Tellinghuise. A study of statistical error in isothermal titration calorimetry. Analytical biochemistry. vol 321. issue 1. 2004-04-23. PMID:12963058. |
the standard errors in the key parameters-the equilibrium constant ko and the enthalpy deltaho-are assessed from the variance-covariance matrix computed for exactly fitting data. |
2004-04-23 |
2023-08-12 |
Not clear |
| Juan Arredondo, Vu Thuong Nguyen, Alexander I Chernyavsky, Dani Bercovich, Avi Orr-Urtreger, Douglas E Vetter, Sergei A Grand. Functional role of alpha7 nicotinic receptor in physiological control of cutaneous homeostasis. Life sciences. vol 72. issue 18-19. 2003-04-04. PMID:12628457. |
we studied in vitro effects of functional inactivation of alpha7 receptor on the expression of apoptosis regulators in keratinocytes (kc) lacking alpha7 nachr, and extracellular matrix regulators in the skin of alpha7 knockout (ko) mice. |
2003-04-04 |
2023-08-12 |
mouse |
| Juan Arredondo, Vu Thuong Nguyen, Alexander I Chernyavsky, Dani Bercovich, Avi Orr-Urtreger, Douglas E Vetter, Sergei A Grand. Functional role of alpha7 nicotinic receptor in physiological control of cutaneous homeostasis. Life sciences. vol 72. issue 18-19. 2003-04-04. PMID:12628457. |
the skin of alpha7 ko mice featured decreased amounts of the extracellular matrix proteins collagen 1alpha1 and elastin as well as the metalloproteinase-1. |
2003-04-04 |
2023-08-12 |
mouse |
| Hidekazu Kitakata, Yoko Nemoto-Sasaki, Yutaka Takahashi, Toshikazu Kondo, Masayoshi Mai, Naofumi Mukaid. Essential roles of tumor necrosis factor receptor p55 in liver metastasis of intrasplenic administration of colon 26 cells. Cancer research. vol 62. issue 22. 2002-12-17. PMID:12438267. |
the intrasplenic tumor injection induced mrna expressions of vascular endothelial growth factor, heparin-binding epidermal growth factor, matrix metalloproteinase-9, and tissue inhibitor of matrix metalloproteinase-1 at similar levels in the livers of both wt and tnf-rp55 ko mice. |
2002-12-17 |
2023-08-12 |
mouse |
| P Gil-Loyzaga, J Gabrion, M Remezal, B Nguyen-Than-Dao, A Uzie. Incorporation of D-[3H]-glucosamine and L-[3H]-fucose into the developing rat cochlea. Hearing research. vol 57. issue 1. 1992-03-04. PMID:1774210. |
the secretion of carbohydrates, and probably of other matrix components, starts on the spiral limbus and ko region and progressively extends to the organ of corti. |
1992-03-04 |
2023-08-11 |
rat |
| V C Mow, M H Holmes, W M La. Fluid transport and mechanical properties of articular cartilage: a review. Journal of biomechanics. vol 17. issue 5. 1984-08-15. PMID:6376512. |
during the previous decade, it was shown that compression causes the permeability of cartilage to drop in a functional manner described by k = ko exp (epsilon m) where ko and m were defined as intrinsic permeability parameters and epsilon is the dilatation of the solid matrix (epsilon = tr delta u). |
1984-08-15 |
2023-08-12 |
Not clear |