| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M B Genter, B M Warner, M Medvedovic, M A Sarto. Comparison of rat olfactory mucosal responses to carcinogenic and non-carcinogenic chloracetanilides. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 47. issue 6. 2009-07-16. PMID:19425180. |
because we have previously shown that matrix metalloproteinase-2 (mmp2) is activated in om by alachlor, in the present studies we evaluated both mmp2 activation and changes in om gene expression in response to carcinogenic and non-carcinogenic chloracetanilide treatments. |
2009-07-16 |
2023-08-12 |
rat |
| Georgia Agiostratidou, Maomi Li, Kimita Suyama, Ines Badano, Rinat Keren, Su Chung, Amy Anzovino, James Hulit, Binzhi Qian, Boumediene Bouzahzah, Eliseo Eugenin, Olivier Loudig, Greg R Phillips, Joseph Locker, Rachel B Haza. Loss of retinal cadherin facilitates mammary tumor progression and metastasis. Cancer research. vol 69. issue 12. 2009-07-06. PMID:19491271. |
r-cad also suppressed the matrix metalloproteinase 1 (mmp1), mmp2, and cyclooxygenase 2 gene expression associated with pulmonary metastasis. |
2009-07-06 |
2023-08-12 |
human |
| Pei-Li Yao, Yi-Chen Lin, John H Richbur. TNF alpha-mediated disruption of spermatogenesis in response to Sertoli cell injury in rodents is partially regulated by MMP2. Biology of reproduction. vol 80. issue 3. 2009-06-25. PMID:19038859. |
the secretion of matrix mp 2 (mmp2) in primary rat sertoli cell-germ cell cocultures is induced after mehp exposure, and its activity increases in a time-dependent manner. |
2009-06-25 |
2023-08-12 |
rat |
| A Papi, P Rocchi, A M Ferreri, F Guerra, M Orland. Enhanced effects of PPARgamma ligands and RXR selective retinoids in combination to inhibit migration and invasiveness in cancer cells. Oncology reports. vol 21. issue 4. 2009-06-18. PMID:19288012. |
since matrix metalloproteinases (mmps) play a major role in tumor cell invasion, we analyzed the effect of iif and cgz on mmp2 and mmp9 activity and expression. |
2009-06-18 |
2023-08-12 |
Not clear |
| Christina Simon, Almuth Einspanie. The hormonal induction of cervical remodeling in the common marmoset monkey (Callithrix jacchus). Reproduction (Cambridge, England). vol 137. issue 3. 2009-06-15. PMID:19106202. |
furthermore, morphological changes such as loosening of the connective tissue structure and decline in collagen content, an increase in the number of eosinophils, increased the expression of matrix metalloproteinases (mmp1) and mmp2, as well as gene and protein expression of the rlx receptor rxfp1 could be detected in the cervical tissue after all hormone treatments, compared with controls. |
2009-06-15 |
2023-08-12 |
human |
| Amy N Abell, Deborah A Granger, Nancy L Johnson, Nicole Vincent-Jordan, Christopher F Dibble, Gary L Johnso. Trophoblast stem cell maintenance by fibroblast growth factor 4 requires MEKK4 activation of Jun N-terminal kinase. Molecular and cellular biology. vol 29. issue 10. 2009-06-04. PMID:19289495. |
isolated mekk4 kinase-inactive trophoblast stem (ts) cells cultured under undifferentiating, self-renewing conditions in the presence of fibroblast growth factor 4 (fgf4) display increased expression of slug, twist, and matrix metalloproteinase 2 (mmp2), loss of e-cadherin, and hyperinvasion of extracellular matrix, each a hallmark of emt. |
2009-06-04 |
2023-08-12 |
mouse |
| Kou-Gi Shyu, Bao-Wei Wang, Hang Chan. Hyperbaric oxygen activates discoidin domain receptor 2 via tumour necrosis factor-alpha and the p38 MAPK pathway to increase vascular smooth muscle cell migration through matrix metalloproteinase 2. Clinical science (London, England : 1979). vol 116. issue 7. 2009-05-14. PMID:18821853. |
hbo increased activated mmp2 (matrix metalloproteinase 2) protein expression, and ddr2 sirna abolished the induction of activated mmp2 expression induced by hbo. |
2009-05-14 |
2023-08-12 |
rat |
| María Mónica Remedi, Ana Carolina Donadio, Gustavo Alberto Chiabrand. Polymorphonuclear cells stimulate the migration and metastatic potential of rat sarcoma cells. International journal of experimental pathology. vol 90. issue 1. 2009-05-14. PMID:19200250. |
the up-regulation in mmp2 associated with upar and mt1-mmp conserved expression may be related to an increased extracellular matrix proteolysis. |
2009-05-14 |
2023-08-12 |
human |
| Zhiyong Mi, Hongtao Guo, M Benjamin Russell, Yingmiao Liu, Bruce A Sullenger, Paul C Ku. RNA aptamer blockade of osteopontin inhibits growth and metastasis of MDA-MB231 breast cancer cells. Molecular therapy : the journal of the American Society of Gene Therapy. vol 17. issue 1. 2009-05-05. PMID:18985031. |
critical enzymatic components of the opn signal transduction pathways, pi3k, jnk1/2, src and akt, and mediators of extracellular matrix degradation, matrix metalloproteinase 2 (mmp2) and uroplasminogen activator (upa), are significantly decreased following exposure to opn-r3. |
2009-05-05 |
2023-08-12 |
human |
| Dylan N Clements, Noel Fitzpatrick, Stuart D Carter, Philip J R Da. Cartilage gene expression correlates with radiographic severity of canine elbow osteoarthritis. Veterinary journal (London, England : 1997). vol 179. issue 2. 2009-04-14. PMID:17938000. |
the levels of expression of type i collagen alpha2 chain (col1a2), type iii collagen alpha1 chain (col3a1), lumican (lum), matrix metalloproteinase-2 (mmp2), -9 (mmp9) and -13 (mmp13) genes were increased and the expression of tissue inhibitor of metalloproteinase-2 (timp2) and cathepsin d (ctsd) genes were decreased in oa cartilage relative to normal cartilage. |
2009-04-14 |
2023-08-12 |
Not clear |
| Premila Paiva, Lois A Salamonsen, Ursula Manuelpillai, Evdokia Dimitriadi. Interleukin 11 inhibits human trophoblast invasion indicating a likely role in the decidual restraint of trophoblast invasion during placentation. Biology of reproduction. vol 80. issue 2. 2009-03-27. PMID:18987331. |
interleukin 11 (100 ng/ml) had no effect on matrix metallopeptidases 2 and 9 (mmp2 and mmp9), tissue inhibitors of mmp (timp1, timp2, and timp3), plasminogen activator urokinase (plau), plasminogen activator urokinase receptor (plaur), and serpin peptidase inhibitors 1 and 2 (serpine1 and serpine2) in evt-conditioned media and/or cell lysates. |
2009-03-27 |
2023-08-12 |
human |
| Heesang Song, Yonghe Li, Jiyeon Lee, Alan L Schwartz, Guojun B. Low-density lipoprotein receptor-related protein 1 promotes cancer cell migration and invasion by inducing the expression of matrix metalloproteinases 2 and 9. Cancer research. vol 69. issue 3. 2009-03-23. PMID:19176371. |
here, we reveal a novel mechanism by which lrp1 induces the expression of matrix metalloproteinase 2 (mmp2) and mmp9 and thereby promotes the migration and invasion of human glioblastoma u87 cells. |
2009-03-23 |
2023-08-12 |
human |
| S Horstmann, J A Koziol, F Martinez-Torres, S Nagel, H Gardner, S Wagne. Sonographic monitoring of mass effect in stroke patients treated with hypothermia. Correlation with intracranial pressure and matrix metalloproteinase 2 and 9 expression. Journal of the neurological sciences. vol 276. issue 1-2. 2009-03-17. PMID:18834996. |
we also determined matrix metalloproteinase 2 (mmp2) and matrix metalloproteinase 9 (mmp9) in serum by zymography. |
2009-03-17 |
2023-08-12 |
Not clear |
| Zuzanna Szymańska, Jakub Urbański, Anna Marciniak-Czochr. Mathematical modelling of the influence of heat shock proteins on cancer invasion of tissue. Journal of mathematical biology. vol 58. issue 4-5. 2009-03-12. PMID:18807037. |
according to experimental data, inhibition of one of these proteins, hsp90, slows down cancer cells while they are invading tissue, but does not affect the synthesis of matrix metalloproteinases (mmp2 and mmp9), which are very important for cancer metastasis, acting as extracellular matrix (ecm) degrading enzymes. |
2009-03-12 |
2023-08-12 |
Not clear |
| Magda Gioia, Susanna Monaco, Philippe E Van Den Steen, Diego Sbardella, Giuseppe Grasso, Stefano Marini, Christopher M Overall, Ghislain Opdenakker, Massimo Colett. The collagen binding domain of gelatinase A modulates degradation of collagen IV by gelatinase B. Journal of molecular biology. vol 386. issue 2. 2009-02-20. PMID:19109975. |
its remodeling is executed by a family of matrix metalloproteinases (mmps), of which the constitutive gelatinase a (mmp2) and the inducible gelatinase b (mmp9) are key examples. |
2009-02-20 |
2023-08-12 |
human |
| Fabien Guegan, Florence Tatin, Thierry Leste-Lasserre, Guillaume Drutel, Elisabeth Genot, Violaine Morea. p190B RhoGAP regulates endothelial-cell-associated proteolysis through MT1-MMP and MMP2. Journal of cell science. vol 121. issue Pt 12. 2009-01-30. PMID:18505793. |
in addition, our data reveal an unsuspected role for p190b in the expression of the two collaborative proteases mt1-mmp and mmp2, thereby affecting matrix remodelling and angiogenesis. |
2009-01-30 |
2023-08-12 |
human |
| Meining Li, Jun Xie, Le Cheng, Bingmei Chang, Ying Wang, Xiaoqin Lan, Dong Zhang, Yunqin Yin, Niuliang Chen. Suppression of invasive properties of colorectal carcinoma SW480 cells by 15-hydroxyprostaglandin dehydrogenase gene. Cancer investigation. vol 26. issue 9. 2008-12-12. PMID:19034772. |
the results showed that re-expression of 15-pgdh suppresed matrix metalloproteinase-2 (mmp2) synthesis and secretion. |
2008-12-12 |
2023-08-12 |
Not clear |
| Anna M Wasilewska, Walentyna M Zoch-Zwier. Urinary levels of matrix metalloproteinases and their tissue inhibitors in nephrotic children. Pediatric nephrology (Berlin, Germany). vol 23. issue 10. 2008-11-18. PMID:18594870. |
the aim of this study was to determine the effects of cyclosporine a (cya) on urinary levels of matrix metalloproteinase 2 and 9 (mmp2, mmp9) and their tissue inhibitors 1 and 2 (timp1, timp2) in steroid-dependent nephrotic syndrome (sdns). |
2008-11-18 |
2023-08-12 |
human |
| Li Qin, Lan Liao, Aisling Redmond, Leonie Young, Yuhui Yuan, Hongwu Chen, Bert W O'Malley, Jianming X. The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression. Molecular and cellular biology. vol 28. issue 19. 2008-10-20. PMID:18644862. |
the aib1 oncogene promotes breast cancer metastasis by activation of pea3-mediated matrix metalloproteinase 2 (mmp2) and mmp9 expression. |
2008-10-20 |
2023-08-12 |
mouse |
| Li Qin, Lan Liao, Aisling Redmond, Leonie Young, Yuhui Yuan, Hongwu Chen, Bert W O'Malley, Jianming X. The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression. Molecular and cellular biology. vol 28. issue 19. 2008-10-20. PMID:18644862. |
molecular analyses revealed that aib1 served as a pea3 coactivator and formed complexes with pea3 on matrix metalloproteinase 2 (mmp2) and mmp9 promoters to enhance their expression in both mouse and human breast cancer cells. |
2008-10-20 |
2023-08-12 |
mouse |