| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Megumi Iiizumi, Sucharita Bandyopadhyay, Sudha K Pai, Misako Watabe, Shigeru Hirota, Sadahiro Hosobe, Taisei Tsukada, Kunio Miura, Ken Saito, Eiji Furuta, Wen Liu, Fei Xing, Hiroshi Okuda, Aya Kobayashi, Kounosuke Watab. RhoC promotes metastasis via activation of the Pyk2 pathway in prostate cancer. Cancer research. vol 68. issue 18. 2008-10-14. PMID:18794150. |
we also found that rhoc significantly augmented the invasion and motility of prostate tumor cells by activating matrix metalloproteinases 2 and 9 (mmp2 and mmp9) in vitro. |
2008-10-14 |
2023-08-12 |
mouse |
| Michiko Yamada, Yoriko Sankoda, Ryuichi Tatsumi, Wataru Mizunoya, Yoshihide Ikeuchi, Kenji Sunagawa, Ronald E Alle. Matrix metalloproteinase-2 mediates stretch-induced activation of skeletal muscle satellite cells in a nitric oxide-dependent manner. The international journal of biochemistry & cell biology. vol 40. issue 10. 2008-10-02. PMID:18403250. |
therefore, results from these experiments provide evidence that no-activated mmp2 may cause release of hgf from the extracellular matrix of satellite cells and contribute to satellite cell activation. |
2008-10-02 |
2023-08-12 |
rat |
| Urara Tamahashi, Jiro Kumagai, Touichiro Takizawa, Masaki Sekine, Yoshinobu Eish. Expression and intracellular localization of matrix metalloproteinases in intraductal papillary mucinous neoplasms of the pancreas. Virchows Archiv : an international journal of pathology. vol 453. issue 1. 2008-09-19. PMID:18500535. |
to analyze the expression of matrix metalloproteinases (mmps) and their relationships with the histological grades of the intraductal papillary mucinous neoplasm (ipmn) of the pancreas, we examined the frequency of expression and intracellular localization of mmp1, mmp2, mmp3, mmp7, and mmp9 in ipmn by immunohistochemistry. |
2008-09-19 |
2023-08-12 |
Not clear |
| Clarke G Tankersley, Hunter C Champion, Eiki Takimoto, Kathleen Gabrielson, Djahida Bedja, Vikas Misra, Hazim El-Haddad, Richard Rabold, Wayne Mitzne. Exposure to inhaled particulate matter impairs cardiac function in senescent mice. American journal of physiology. Regulatory, integrative and comparative physiology. vol 295. issue 1. 2008-09-03. PMID:18448608. |
measurements of natriuretic peptide (atrial and brain) transcription and matrix metalloproteinase (mmp2 and mmp9) activity in heart tissue are significantly (p < 0.05) amplified with senescence and exposure to cb, pointing to increased cardiac stress and remodeling. |
2008-09-03 |
2023-08-12 |
mouse |
| Sahza Hatibović-Kofman, Lin Raimundo, Lei Zheng, Lawrence Chong, Manfred Friedman, Jens Ove Andrease. Fracture resistance and histological findings of immature teeth treated with mineral trioxide aggregate. Dental traumatology : official publication of International Association for Dental Traumatology. vol 24. issue 3. 2008-09-02. PMID:18410392. |
one tooth from each group was selected randomly for a histological study, examining matrix metalloproteinases (mmp2 and mmp14) and tissue inhibitor of metalloproteinase (timp). |
2008-09-02 |
2023-08-12 |
Not clear |
| Ling-Feng Wang, Chen-Yu Chien, Wen-Rei Kuo, Chin-Feng Tai, Suh-Hang Hank Ju. Matrix metalloproteinase-2 gene polymorphisms in nasal polyps. Archives of otolaryngology--head & neck surgery. vol 134. issue 8. 2008-08-29. PMID:18711060. |
to systematically investigate the role of matrix metalloproteinase-2 (mmp2) tagging single nucleotide polymorphisms (snps) and promoter functional polymorphism in the development of nasal polyps in a chinese population in taiwan. |
2008-08-29 |
2023-08-12 |
Not clear |
| Charles J Lockwood, Ceyda Oner, Yesim H Uz, Umit A Kayisli, S Joseph Huang, Lynn F Buchwalder, William Murk, Edmund F Funai, Frederick Schat. Matrix metalloproteinase 9 (MMP9) expression in preeclamptic decidua and MMP9 induction by tumor necrosis factor alpha and interleukin 1 beta in human first trimester decidual cells. Biology of reproduction. vol 78. issue 6. 2008-08-28. PMID:18276934. |
in contrast, immunostaining for mmp2 and tissue inhibitor of matrix metalloproteinases 1 and 2 (timp1 and timp2) were similar in preeclamptic and control groups. |
2008-08-28 |
2023-08-12 |
human |
| Liqun Jiang, Mingyi Wang, Jing Zhang, Robert E Monticone, Richard Telljohann, Gaia Spinetti, Gianfranco Pintus, Edward G Lakatt. Increased aortic calpain-1 activity mediates age-associated angiotensin II signaling of vascular smooth muscle cells. PloS one. vol 3. issue 5. 2008-08-19. PMID:18493299. |
angiotensin ii (ang ii) signaling, including matrix metalloproteinase type ii (mmp2) activation, has been linked to an age-associated increase in migration capacity of vascular smooth muscle cells (vsmc), and to other proinflammatory features of arterial aging. |
2008-08-19 |
2023-08-12 |
Not clear |
| Hong Mu, Xinwen Wang, Peter Lin, Qizhi Yao, Changyi Che. Nitrotyrosine promotes human aortic smooth muscle cell migration through oxidative stress and ERK1/2 activation. Biochimica et biophysica acta. vol 1783. issue 9. 2008-08-13. PMID:18460343. |
nitrotyrosine significantly increased the expression of some key cell migration-related molecules including pdgf receptor-b, matrix metalloproteinase 2 (mmp2) and integrins alphav and beta3 at both mrna and protein levels in aosmc (p<0.01). |
2008-08-13 |
2023-08-12 |
human |
| M Amati, M Tomasetti, M Scartozzi, L Mariotti, M Ciuccarelli, M Valentino, M Governa, L Santarell. [Biomarkers for prevention and early diagnosis of malignant pleural mesothelioma]. Giornale italiano di medicina del lavoro ed ergonomia. vol 29. issue 3 Suppl. 2008-07-25. PMID:18409713. |
94 asbestos-exposed subjects, 22 patients with mm, and 54 healthy subjects were recruited for evaluation of the significance of 8-hydroxy-2'-deoxy-guanosine (80hdg) in white blood cells and plasma concentrations of soluble mesothelin-related peptides (smrps), angiogenic factors (pdgfbeta, hgf, bfgf, vegfbeta), and matrix proteases (mmp2, mmp9, timp1, timp2) for potential early detection of mm. |
2008-07-25 |
2023-08-12 |
human |
| V Polyakova, S Miyagawa, Z Szalay, J Risteli, S Kosti. Atrial extracellular matrix remodelling in patients with atrial fibrillation. Journal of cellular and molecular medicine. vol 12. issue 1. 2008-07-22. PMID:18194448. |
as compared with sr, collagen vi, matrix metalloproteinases mmp2, mmp9 and timp1 were significantly increased while timp3 and timp4 remained unchanged in all af groups. |
2008-07-22 |
2023-08-12 |
Not clear |
| F Révillion, V Lhotellier, L Hornez, A Leroy, M C Baranzelli, S Giard, J Bonneterre, J-P Peyra. Real-time reverse-transcription PCR to quantify a panel of 19 genes in breast cancer: relationships with sentinel lymph node invasion. The International journal of biological markers. vol 23. issue 1. 2008-07-18. PMID:18409145. |
we looked at cytokeratin 19 (ck19), mucin-1 (muc1), mammaglobin (mgb1), cyclin d1 (ccnd1), the four members of the her/erbb growth factor receptor family (egfr, her2-4), insulin-like growth factor-1 receptor (igf-1r), estradiol receptors (eralpha, erbeta), progesterone receptor (pr), vascular endothelial growth factors (vegf, vegf-c), urokinase-like plasminogen activator (upa), matrix metalloproteinases 2 and 9 (mmp2, mmp9), ets-related transcription factor erm, and e-cadherin (cdh1). |
2008-07-18 |
2023-08-12 |
Not clear |
| Gulay Filiz, Katherine A Price, Aphrodite Caragounis, Tai Du, Peter J Crouch, Anthony R Whit. The role of metals in modulating metalloprotease activity in the AD brain. European biophysics journal : EBJ. vol 37. issue 3. 2008-07-16. PMID:18270696. |
increased kinase activity resulted in up-regulated matrix metalloprotease (mmp2 and mmp3) activity resulting in enhanced degradation of secreted a beta. |
2008-07-16 |
2023-08-12 |
Not clear |
| Charles S Lieber, David G Weiss, Fiorenzo Paronett. Value of fibrosis markers for staging liver fibrosis in patients with precirrhotic alcoholic liver disease. Alcoholism, clinical and experimental research. vol 32. issue 6. 2008-07-01. PMID:18422837. |
seven serum markers (tissue inhibitor of matrix metalloproteinase 1 [timp1], tenascin, collagen vi, amino-terminal propeptide of type iii collagen [piiinp], matrix metalloproteinases [mmp2], laminin, and hyaluronic acid [ha]) representing various aspects of collagen and extracellular matrix deposition and degradation, have been proposed as noninvasive surrogates for liver biopsy. |
2008-07-01 |
2023-08-12 |
Not clear |
| Raj S Mitra, Mitsuo Goto, Julia S Lee, Diana Maldonado, Jeremy M G Taylor, Quintin Pan, Thomas E Carey, Carol R Bradford, Mark E Prince, Kitrina G Cordell, Keith L Kirkwood, Nisha J D'Silv. Rap1GAP promotes invasion via induction of matrix metalloproteinase 9 secretion, which is associated with poor survival in low N-stage squamous cell carcinoma. Cancer research. vol 68. issue 10. 2008-06-24. PMID:18483282. |
the objective of the current study was to investigate the effects of rap1gap on invasion and progression of head and neck squamous cell carcinoma (scc) and the role of matrix metalloproteinase (mmp) 9 and mmp2 in this process. |
2008-06-24 |
2023-08-12 |
human |
| Raj S Mitra, Mitsuo Goto, Julia S Lee, Diana Maldonado, Jeremy M G Taylor, Quintin Pan, Thomas E Carey, Carol R Bradford, Mark E Prince, Kitrina G Cordell, Keith L Kirkwood, Nisha J D'Silv. Rap1GAP promotes invasion via induction of matrix metalloproteinase 9 secretion, which is associated with poor survival in low N-stage squamous cell carcinoma. Cancer research. vol 68. issue 10. 2008-06-24. PMID:18483282. |
mmp2 and mmp9 are enzymes that mediate scc invasion via degradation of the extracellular matrix. |
2008-06-24 |
2023-08-12 |
human |
| Weidong Hu, Xinming Zhen, Bin Xiong, Bicheng Wang, Weibing Zhang, Wenhui Zho. CXCR6 is expressed in human prostate cancer in vivo and is involved in the in vitro invasion of PC3 and LNCap cells. Cancer science. vol 99. issue 7. 2008-06-17. PMID:18452560. |
furthermore, in contrast to cxcl12, which enhanced the activity of matrix metalloproteinase (mmp) 9 and mmp2 in pc3 and lncap, cxcl16 ligation resulted in stronger mmp9 and mmp2 activity in lncap but not in pc3. |
2008-06-17 |
2023-08-12 |
human |
| Dominique Trudel, Yves Fradet, François Meyer, François Harel, Bernard Têt. Membrane-type-1 matrix metalloproteinase, matrix metalloproteinase 2, and tissue inhibitor of matrix proteinase 2 in prostate cancer: identification of patients with poor prognosis by immunohistochemistry. Human pathology. vol 39. issue 5. 2008-06-16. PMID:18329693. |
membrane-type-1 mmp (mmp14) activates mmp2 using pro-mmp2 specific inhibitor, tissue inhibitor of matrix proteinase 2 (timp2), as a receptor. |
2008-06-16 |
2023-08-12 |
Not clear |
| N Maolood, H Hardin-Pouzet, V Grange-Messen. Matrix metalloproteinases MMP2 and MMP9 are upregulated by noradrenaline in the mouse neuroendocrine hypothalamus. The European journal of neuroscience. vol 27. issue 5. 2008-06-03. PMID:18364034. |
matrix metalloproteinases mmp2 and mmp9 are upregulated by noradrenaline in the mouse neuroendocrine hypothalamus. |
2008-06-03 |
2023-08-12 |
mouse |
| Svetlana Kondratiev, Douglas R Gnepp, Evgeny Yakirevich, Edmond Sabo, Donald J Annino, Elie Rebeiz, Nora V Lave. Expression and prognostic role of MMP2, MMP9, MMP13, and MMP14 matrix metalloproteinases in sinonasal and oral malignant melanomas. Human pathology. vol 39. issue 3. 2008-05-21. PMID:18045645. |
expression and prognostic role of mmp2, mmp9, mmp13, and mmp14 matrix metalloproteinases in sinonasal and oral malignant melanomas. |
2008-05-21 |
2023-08-12 |
Not clear |