| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mikala Egeblad, H-C Jennifer Shen, Danielle J Behonick, Lisa Wilmes, Alexandra Eichten, Lidiya V Korets, Farrah Kheradmand, Zena Werb, Lisa M Coussen. Type I collagen is a genetic modifier of matrix metalloproteinase 2 in murine skeletal development. Developmental dynamics : an official publication of the American Association of Anatomists. vol 236. issue 6. 2007-08-24. PMID:17440987. |
recessive inactivating mutations in human matrix metalloproteinase 2 (mmp2, gelatinase a) are associated with syndromes that include abnormal facial appearance, short stature, and severe bone loss. |
2007-08-24 |
2023-08-12 |
mouse |
| Ming-man Zhang, Lü-nan Yan, De-hua Li, Xing-hua Gou, Jiang-wen Liu, Zhi Su, Lei Han, Lan-ying Zha. [Inhibition of adenovirus-mediated gene transfer of antisense matrix metalloproteinase-2 on hepatocellular carcinoma growth in vivo]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology. vol 13. issue 9. 2007-08-23. PMID:16174456. |
to investigate if a recombinant adenoviral vector carrying antisense matrix metalloproteinase-2 (mmp2) gene would inhibit the growth of hepatocellular carcinoma (hcc) in vivo. |
2007-08-23 |
2023-08-12 |
Not clear |
| Massimiliano De Bortoli, Robert C Castellino, Darlene G Skapura, Jianhe J Shen, Jack M Su, Heidi V Russell, M John Hicks, Tsz-Kwong Man, John Y H Ki. Patched haploinsufficient mouse rhabdomyosarcoma overexpress secreted phosphoprotein 1 and matrix metalloproteinases. European journal of cancer (Oxford, England : 1990). vol 43. issue 8. 2007-08-20. PMID:17467979. |
overexpressed genes include secreted phosphoprotein 1 (spp1, osteopontin), and matrix metalloproteinases-2 and -14 (mmp2 and mmp14). |
2007-08-20 |
2023-08-12 |
mouse |
| Marie Piette, Brigitte Evrard, Francis Frankenne, Patrice Chiap, Pascal Bertholet, Delphine Castagne, Jean-Michel Foidart, Luc Delattre, Géraldine Pie. Pharmacokinetic study of a new synthetic MMP inhibitor (Ro 28-2653) after IV and oral administration of cyclodextrin solutions. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. vol 28. issue 3. 2007-08-06. PMID:16520026. |
ro 28-2653 (5-biphenyl-4-yl-5-[4-(4-nitro-phenyl)-piperazin-1-yl]-pyrimidine-2,4,6-trione) is a new synthetic inhibitor of matrix metalloproteinases (mmps) with a high selectivity towards mmp2, mmp9 and membrane type 1-mmp. |
2007-08-06 |
2023-08-12 |
Not clear |
| Harcharan K Rooprai, Ioannis Kyriazis, Robert K Nuttall, Dylan R Edwards, Daniel Zicha, Deborah Aubyn, Derek Davies, Richard Gullan, Geoffrey J Pilkingto. Inhibition of invasion and induction of apoptosis by selenium in human malignant brain tumour cells in vitro. International journal of oncology. vol 30. issue 5. 2007-07-17. PMID:17390030. |
rt-pcr results showed downregulation of the gene expression of 6 matrix metalloproteases (mmp2, 9, 14, 15, 16, 24), their inhibitors, timps and epidermal growth factor receptor, in ipsb-18 cells treated with 2, 4 and 8 microg/ml of selenium. |
2007-07-17 |
2023-08-12 |
human |
| Sandrine Gremlich, Daniel Nguyen, Danielle Reymondin, Patrick Hohlfeld, Yvan Vial, Steven S Witkin, Stefan Gerbe. Fetal MMP2/MMP9 polymorphisms and intrauterine growth restriction risk. Journal of reproductive immunology. vol 74. issue 1-2. 2007-07-16. PMID:17367869. |
matrix metalloproteinase-2 (mmp-2) and mmp-9 are highly involved in early embryo implantation and three functional polymorphisms have been described for these genes: mmp2 c-1306t, mmp9 c-1562t and mmp9 (ca)n repeat. |
2007-07-16 |
2023-08-12 |
Not clear |
| Takanori Kitamura, Kohei Kometani, Hiroki Hashida, Akihiro Matsunaga, Hiroyuki Miyoshi, Hisahiro Hosogi, Masahiro Aoki, Masanobu Oshima, Masakazu Hattori, Arimichi Takabayashi, Nagahiro Minato, Makoto M Taket. SMAD4-deficient intestinal tumors recruit CCR1+ myeloid cells that promote invasion. Nature genetics. vol 39. issue 4. 2007-06-06. PMID:17369830. |
these cd34(+) imcs express the matrix metalloproteinases mmp9 and mmp2 and the cc-chemokine receptor 1 (ccr1) and migrate toward the ccr1 ligand ccl9. |
2007-06-06 |
2023-08-12 |
mouse |
| Hervé Pageon, Hilaire Bakala, Vincent M Monnier, Daniel Asselinea. Collagen glycation triggers the formation of aged skin in vitro. European journal of dermatology : EJD. vol 17. issue 1. 2007-05-25. PMID:17324821. |
these include the activation of fibroblasts, increase of matrix molecules (collagen type iii and collagen type iv) and metalloproteinase production (mmp1, mmp2 and mmp9), thickening of the basement membrane zone, and more strikingly, the modification of alpha6 and beta1 integrin patterns especially in epidermis, in a way closely resembling aged skin in vivo. |
2007-05-25 |
2023-08-12 |
Not clear |
| Yiqin Zhang, Henry J Klassen, Budd A Tucker, Maria-Thereza R Perez, Michael J Youn. CNS progenitor cells promote a permissive environment for neurite outgrowth via a matrix metalloproteinase-2-dependent mechanism. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 17. 2007-05-15. PMID:17460063. |
transplantation of retinal progenitor cells induced increased matrix metalloproteinase-2 (mmp2) secretion, partly from activated glial cells, which was then activated by neuronally expressed mmp14. |
2007-05-15 |
2023-08-12 |
mouse |
| May J Reed, Nathan Karres, Daniel Eyman, Abigail Cruz, Rolf A Brekken, Stephen Plymat. The effects of aging on tumor growth and angiogenesis are tumor-cell dependent. International journal of cancer. vol 120. issue 4. 2007-05-14. PMID:17131319. |
in contrast to the b16/f10, tramp-c2 tumors had an extracellular matrix with significantly higher levels of mmp2 and mmp9 expression and activity. |
2007-05-14 |
2023-08-12 |
mouse |
| b' Edwige Tellier, Anne N\\xc3\\xa8gre-Salvayre, Beatrice Bocquet, Shigeyoshi Itohara, Yusuf A Hannun, Robert Salvayre, Nathalie Aug\\xc3\\xa. Role for furin in tumor necrosis factor alpha-induced activation of the matrix metalloproteinase/sphingolipid mitogenic pathway. Molecular and cellular biology. vol 27. issue 8. 2007-05-08. PMID:17283058.' |
using biochemical, molecular, and pharmacological approaches, we found that nsmase activation triggered by tnf-alpha is required for tnf-alpha-induced proliferation and in turn requires a proteolytic cascade involving furin, membrane type 1 matrix metalloproteinase (mt1-mmp), and mmp2, and leading finally to extracellular signal-regulated kinase 1/2 (erk1/2) phosphorylation and dna synthesis, in smooth muscle cells (smc) and fibroblasts. |
2007-05-08 |
2023-08-12 |
mouse |
| Luigi Fabrizio Rodella, Francesca Bonomini, Rita Rezzani, Sandra Tengattini, Tony Hayek, Michael Aviram, Shlomo Keidar, Raymond Coleman, Rossella Bianch. Atherosclerosis and the protective role played by different proteins in apolipoprotein E-deficient mice. Acta histochemica. vol 109. issue 1. 2007-04-12. PMID:17046051. |
inducible nitric oxide synthase (inos, nos2), vascular endothelial growth factor (vegf) and matrix metalloproteinase-2 (mmp2). |
2007-04-12 |
2023-08-12 |
mouse |
| Erika Pastrana, Maria Teresa Moreno-Flores, Jesus Avila, Francisco Wandosell, Liliana Minichiello, Javier Diaz-Nid. BDNF production by olfactory ensheathing cells contributes to axonal regeneration of cultured adult CNS neurons. Neurochemistry international. vol 50. issue 3. 2007-04-10. PMID:17157963. |
combining bdnf with other extracellular proteins such as matrix metalloproteinase 2 (mmp2) further augmented this effect. |
2007-04-10 |
2023-08-12 |
Not clear |
| Cornelia Neidlinger-Wilke, Karin Würtz, Jill P G Urban, Wolfgang Börm, Markus Arand, Anita Ignatius, Hans-Joachim Wilke, Lutz E Clae. Regulation of gene expression in intervertebral disc cells by low and high hydrostatic pressure. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. vol 15 Suppl 3. 2007-04-05. PMID:16680448. |
cells were harvested 24 h after the end of stimulation and changes in the expression of genes known to influence ivd matrix turnover (collagen-i, collagen-ii, aggrecan, mmp1, mmp2, mmp3, mmp13) were analyzed by real-time rt-pcr. |
2007-04-05 |
2023-08-12 |
human |
| Cornelia Neidlinger-Wilke, Karin Würtz, Jill P G Urban, Wolfgang Börm, Markus Arand, Anita Ignatius, Hans-Joachim Wilke, Lutz E Clae. Regulation of gene expression in intervertebral disc cells by low and high hydrostatic pressure. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. vol 15 Suppl 3. 2007-04-05. PMID:16680448. |
low hydrostatic pressure had no influence on the expression of matrix metalloproteinases (mmp1, mmp2, mmp3 and mmp13). |
2007-04-05 |
2023-08-12 |
human |
| Ming-man Zhang, Lü-nan Yan, De-hua Li, Jiang-wen Liu, Xing-hua Gou, Lei Han, Zhi Su, Lan-ying Zhao, Hai-yang H. [Recombinant adenovirus vectors carrying antisense matrix metalloproteinase-2 inhibits hepatocellular carcinoma growth in vivo]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition. vol 37. issue 4. 2007-04-02. PMID:16909593. |
to investigate the inhibitory effect of a recombinant adenoviral vector carrying antisense matrix metalloproteinase-2(mmp2) on the growth of hepatocellular carcinoma(hcc) in vivo. |
2007-04-02 |
2023-08-12 |
Not clear |
| Julio Rodriguez-Lopez, Eva Perez-Pampin, Juan J Gomez-Reino, Antonio Gonzale. Regulatory polymorphisms in extracellular matrix protease genes and susceptibility to rheumatoid arthritis: a case-control study. Arthritis research & therapy. vol 8. issue 1. 2007-01-29. PMID:16356191. |
nine snps in eight genes were selected by bibliographic search, including snps in the genes encoding matrix metalloproteinase (mmp)1, mmp2, mmp3, mmp7, mmp9, mmp13, plasminogen activator, tissue type (plat) and pai-1. |
2007-01-29 |
2023-08-12 |
Not clear |
| Jorge García-Alvarez, Remedios Ramirez, Clara L Sampieri, Robert K Nuttall, Dylan R Edwards, Moises Selman, Annie Pard. Membrane type-matrix metalloproteinases in idiopathic pulmonary fibrosis. Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG. vol 23. issue 1. 2006-12-13. PMID:16933466. |
some secreted matrix metalloproteinases (mmps) as mmp2 are highly upregulated in ipf lungs. |
2006-12-13 |
2023-08-12 |
Not clear |
| R W K Wu, E S M Chu, C M N Yow, J Y Che. Photodynamic effects on nasopharyngeal carcinoma (NPC) cells with 5-aminolevulinic acid or its hexyl ester. Cancer letters. vol 242. issue 1. 2006-12-08. PMID:16442708. |
ala and ala-h mediated pdt not only destroy the cells directly, but also inhibit the expression of matrix metalloproteinase-2 (mmp2) in cells, a maker for tumor metastasis. |
2006-12-08 |
2023-08-12 |
Not clear |
| Debra A Mayes, Yuanjie Hu, Yue Teng, Eric Siegel, Xiaosong Wu, Kishori Panda, Fang Tan, W K Alfred Yung, Yi-Hong Zho. PAX6 suppresses the invasiveness of glioblastoma cells and the expression of the matrix metalloproteinase-2 gene. Cancer research. vol 66. issue 20. 2006-12-04. PMID:17047041. |
using real-time quantitative reverse transcription-pcr (rt-pcr), gelatin zymography, and immunohistochemistry assays, the expression of the gene encoding matrix metalloproteinase-2 (mmp2) in gbm cell lines grown in vitro or in intracranial xenografts in nude mice was shown to be repressed by either stable or adenoviral-mediated overexpression of pax6. |
2006-12-04 |
2023-08-12 |
mouse |