| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T William Axelrad, Dayanand D Deo, Paulo Ottino, Jennefer Van Kirk, Nicolas G Bazan, Haydee E P Bazan, Jay D Hun. Platelet-activating factor (PAF) induces activation of matrix metalloproteinase 2 activity and vascular endothelial cell invasion and migration. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 18. issue 3. 2004-06-01. PMID:14715700. |
matrix metalloproteinase 2 (mmp2), which degrades type iv collagen, is produced as prommp2. |
2004-06-01 |
2023-08-12 |
human |
| J E Nutt, H P Lazarowicz, J K Mellon, J Lune. Gefitinib ('Iressa', ZD1839) inhibits the growth response of bladder tumour cell lines to epidermal growth factor and induces TIMP2. British journal of cancer. vol 90. issue 8. 2004-05-26. PMID:15083203. |
zymography of the conditioned medium from rt112 cells treated with egf and gefitinib showed a decrease in matrix metalloproteinase 2 (mmp2) concentrations. |
2004-05-26 |
2023-08-12 |
human |
| Weiling Zhao, Prabhat C Goswami, Mike E C Robbin. Radiation-induced up-regulation of Mmp2 involves increased mRNA stability, redox modulation, and MAPK activation. Radiation research. vol 161. issue 4. 2004-05-25. PMID:15038770. |
we have previously observed time- and dose-dependent increases in matrix metalloproteinase 2 (mmp2) protein levels in rat tubule epithelial cells (nrk52e) after irradiation. |
2004-05-25 |
2023-08-12 |
rat |
| F Gaultier, A Foucault-Bertaud, E Lamy, A L Ejeil, S M Dridi, N Piccardi, A Piccirilli, P Msika, G Godeau, B Gogl. Effects of a vegetable extract from Lupinus albus (LU105) on the production of matrix metalloproteinases (MMP1, MMP2, MMP9) and tissue inhibitor of metalloproteinases (TIMP1, TIMP2) by human gingival fibroblasts in culture. Clinical oral investigations. vol 7. issue 4. 2004-02-18. PMID:12802622. |
effects of a vegetable extract from lupinus albus (lu105) on the production of matrix metalloproteinases (mmp1, mmp2, mmp9) and tissue inhibitor of metalloproteinases (timp1, timp2) by human gingival fibroblasts in culture. |
2004-02-18 |
2023-08-12 |
human |
| Junichiro Kamochi, Tetsuji Tokunaga, Yasushi Tomii, Yoshiyuki Abe, Hiroyuki Hatanaka, Hiroshi Kijima, Hitoshi Yamazaki, Norihito Watanabe, Shohei Matsuzaki, Yoshito Ueyama, Masato Nakamur. Overexpression of the thrombospondin 2 (TSP2) gene modulated by the matrix metalloproteinase family expression and production in human colon carcinoma cell line. Oncology reports. vol 10. issue 4. 2004-02-06. PMID:12792739. |
the transformants with the human tsp2 gene overexpression showed a down-regulation of matrix metalloproteinase 2 (mmp2) and mmp9 in comparison to those with vector-control. |
2004-02-06 |
2023-08-12 |
human |
| Rossella Bianchi, Luigi Rodella, Rita Rezzan. Cyclosporine A up-regulates expression of matrix metalloproteinase 2 and vascular endothelial growth factor in rat heart. International immunopharmacology. vol 3. issue 3. 2003-12-17. PMID:12639820. |
since the immunosuppressive therapy induces myocardial toxicity, the aim of this study was to evaluate in the myocardium of csa-treated rats the expression variations of vascular endothelial growth factor (vegf) and matrix metalloproteinase 2 (mmp2), to verify if: vegf increased, vegf increase was associated with mmp2 increase and they could be considered as repair proteins. |
2003-12-17 |
2023-08-12 |
rat |
| Xue-Pei Zhang, Fang-Jian Zhou, Peng-Fei Shen, Cheng Zhou, Jin-Xing We. [Significance of activated matrix metalloproteinase 2 (MMP2) in progression of bladder transitional cell carcinoma]. Ai zheng = Aizheng = Chinese journal of cancer. vol 22. issue 6. 2003-12-11. PMID:12948424. |
[significance of activated matrix metalloproteinase 2 (mmp2) in progression of bladder transitional cell carcinoma]. |
2003-12-11 |
2023-08-12 |
Not clear |
| Xue-Pei Zhang, Fang-Jian Zhou, Peng-Fei Shen, Cheng Zhou, Jin-Xing We. [Significance of activated matrix metalloproteinase 2 (MMP2) in progression of bladder transitional cell carcinoma]. Ai zheng = Aizheng = Chinese journal of cancer. vol 22. issue 6. 2003-12-11. PMID:12948424. |
activated matrix metalloproteinase 2 (mmp2) play an important role in progression of tumors by degrading the extracellular matrix and basement membrane. |
2003-12-11 |
2023-08-12 |
Not clear |
| Dorina Belotti, Paola Paganoni, Luigi Manenti, Angela Garofalo, Sergio Marchini, Giulia Taraboletti, Raffaella Giavazz. Matrix metalloproteinases (MMP9 and MMP2) induce the release of vascular endothelial growth factor (VEGF) by ovarian carcinoma cells: implications for ascites formation. Cancer research. vol 63. issue 17. 2003-11-06. PMID:14500349. |
matrix metalloproteinases (mmp9 and mmp2) induce the release of vascular endothelial growth factor (vegf) by ovarian carcinoma cells: implications for ascites formation. |
2003-11-06 |
2023-08-12 |
mouse |
| Yongjian Yang, Dongmin Dang, Amha Atakilit, Brian Schmidt, Joseph Regezi, Xiaowu Li, David Eisele, Duncan Ellis, Daniel M Ramo. Specific alpha v integrin receptors modulate K1735 murine melanoma cell behavior. Biochemical and biophysical research communications. vol 308. issue 4. 2003-10-14. PMID:12927791. |
we investigated possible modulators of fn matrix assembly and found that matrix metalloproteinase 2 (mmp2) was activated by alpha v beta 3. alpha v beta 3 integrin was localized to focal contacts whereas alpha v beta 5 was peripherally distributed. |
2003-10-14 |
2023-08-12 |
Not clear |
| Yongjian Yang, Dongmin Dang, Amha Atakilit, Brian Schmidt, Joseph Regezi, Xiaowu Li, David Eisele, Duncan Ellis, Daniel M Ramo. Specific alpha v integrin receptors modulate K1735 murine melanoma cell behavior. Biochemical and biophysical research communications. vol 308. issue 4. 2003-10-14. PMID:12927791. |
mmp2 activation inversely correlated with fn matrix assembly, in that it dramatically reduced the organization of a fn matrix. |
2003-10-14 |
2023-08-12 |
Not clear |
| Yongjian Yang, Dongmin Dang, Amha Atakilit, Brian Schmidt, Joseph Regezi, Xiaowu Li, David Eisele, Duncan Ellis, Daniel M Ramo. Specific alpha v integrin receptors modulate K1735 murine melanoma cell behavior. Biochemical and biophysical research communications. vol 308. issue 4. 2003-10-14. PMID:12927791. |
these results demonstrate that the expression of the alpha v beta 3 complex modulates melanoma cell behavior including activation of src, organization of the cytoskeleton, assembly of the extracellular matrix, cell motility, and activation of mmp2. |
2003-10-14 |
2023-08-12 |
Not clear |
| Yi Sun, Lu-Jia Don. [Role of matrix metalloproteinases in the pathogenesis and therapy of leukemia]. Zhongguo shi yan xue ye xue za zhi. vol 11. issue 3. 2003-09-09. PMID:12844422. |
mmp2 and mmp9 are the unique types of proteinase that hydrolyze the bone structure of excellulary matrix (type iv collagen). |
2003-09-09 |
2023-08-12 |
Not clear |
| Xiaoping Miao, Chunyuan Yu, Wen Tan, Ping Xiong, Gang Liang, Wenfu Lu, Dongxin Li. A functional polymorphism in the matrix metalloproteinase-2 gene promoter (-1306C/T) is associated with risk of development but not metastasis of gastric cardia adenocarcinoma. Cancer research. vol 63. issue 14. 2003-08-13. PMID:12873995. |
matrix metalloproteinase-2 (mmp-2) has been shown to play an importantrole in multiple ways to all stages of cancer initiation and development.we have reported previously a strong association between a functional single nucleotide polymorphism (-1306c/t) in the mmp2 promoter and risk of lung cancer (c. yu et al., cancer res., 62: 6430-6433, 2002). |
2003-08-13 |
2023-08-12 |
human |
| Marian Danilewicz, Beata Sikorska, Małgorzata Wagrowska-Danilewic. Prognostic significance of the immunoexpression of matrix metalloproteinase MMP2 and its inhibitor TIMP2 in laryngeal cancer. Medical science monitor : international medical journal of experimental and clinical research. vol 9. issue 3. 2003-07-31. PMID:12640351. |
prognostic significance of the immunoexpression of matrix metalloproteinase mmp2 and its inhibitor timp2 in laryngeal cancer. |
2003-07-31 |
2023-08-12 |
Not clear |
| Taeseung Lee, Nowokere Esemuede, Bauer E Sumpio, Vivian Gahta. Thrombospondin-1 induces matrix metalloproteinase-2 activation in vascular smooth muscle cells. Journal of vascular surgery. vol 38. issue 1. 2003-07-29. PMID:12844104. |
matrix metalloproteinase-2 (mmp2) is associated with basement membrane and ecm degradation, important processes for cell migration. |
2003-07-29 |
2023-08-12 |
Not clear |
| Q Gao, B Wu, J Zhang, J You, H Zhong, W Fan. [Expression of membrane-type I matrix metalloproteinase and its correlation with gelatinase A activation in cancer cell lines]. Zhonghua bing li xue za zhi = Chinese journal of pathology. vol 28. issue 3. 2003-07-14. PMID:11869527. |
to study the expression of membrane-type i matrix metalloproteinase (mt1-mmp) and its correlation with gelatinase a (mmp2) activation. |
2003-07-14 |
2023-08-12 |
Not clear |
| Lori Holle, Wendy Song, Eric Holle, Yanzhang Wei, Thomas Wagner, Xianzhong Y. A matrix metalloproteinase 2 cleavable melittin/avidin conjugate specifically targets tumor cells in vitro and in vivo. International journal of oncology. vol 22. issue 1. 2003-06-16. PMID:12469190. |
extracellular matrix breakdown as well as increased expression in cancer cells and tumor microvascular endothelial cells make matrix metalloproteinase 2 (mmp2) an attractive target for cancer treatment. |
2003-06-16 |
2023-08-12 |
Not clear |
| Ping Zhan, Edmund Chun Yu Lee, Kathryn Packman, Martin Tenniswoo. Induction of invasive phenotype by Casodex in hormone-sensitive prostate cancer cells. The Journal of steroid biochemistry and molecular biology. vol 83. issue 1-5. 2003-05-23. PMID:12650706. |
rt-pcr based analysis demonstrates that in lncap cells casodex coordinately alters the expression of steady-state level of mrnas of several matrix metalloproteases and their cognate inhibitors (most notably mmp2 and timp1). |
2003-05-23 |
2023-08-12 |
Not clear |
| Masaki Fujita, Yoichi Nakao, Shigeki Matsunaga, Teruaki Nishikawa, Nobuhiro Fusetan. Sodium 1-(12-hydroxy)octadecanyl sulfate, an MMP2 inhibitor, isolated from a tunicate of the family Polyclinidae. Journal of natural products. vol 65. issue 12. 2003-04-30. PMID:12502345. |
sodium 1-(12-hydroxy)octadecanyl sulfate (1) was isolated from a marine tunicate as a matrix metalloproteinase 2 (mmp2) inhibitor. |
2003-04-30 |
2023-08-12 |
Not clear |