| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mei-Jen Chuang, Kuang-Hui Sun, Shye-Jye Tang, Ming-Wei Deng, Yu-Hsin Wu, Jung-Sung Sung, Tai-Lung Cha, Guang-Huan Su. Tumor-derived tumor necrosis factor-alpha promotes progression and epithelial-mesenchymal transition in renal cell carcinoma cells. Cancer science. vol 99. issue 5. 2008-05-19. PMID:18294286. |
we found that expression of il-1 beta, il-6, tnf-alpha, hypoxia-inducible factor-alpha (hif-1 alpha), and matrix metalloproteinase-2 (mmp2) were significantly elevated in high malignancy a498 cells compared to low malignancy 786-o cells. |
2008-05-19 |
2023-08-12 |
Not clear |
| Robin L Seitzman, Vinit B Mahajan, Carol Mangione, Jane A Cauley, Kristine E Ensrud, Katie L Stone, Steven R Cummings, Marc C Hochberg, Teresa A Hillier, Janet S Sinsheimer, Fei Yu, Anne L Colema. Estrogen receptor alpha and matrix metalloproteinase 2 polymorphisms and age-related maculopathy in older women. American journal of epidemiology. vol 167. issue 10. 2008-05-13. PMID:18359774. |
in this study, the authors sought to determine whether single nucleotide polymorphisms in the estrogen receptor alpha (esr1) and matrix metalloproteinase 2 (mmp2) genes are associated with age-related maculopathy (arm) in older women. |
2008-05-13 |
2023-08-12 |
human |
| Hwa Jung Choi, Jae-Soon Eun, Dae Keun Kim, Ri Hua Li, Tae-Yong Shin, Hyunsung Park, Nam-Pyo Cho, Yunjo So. Icariside II from Epimedium koreanum inhibits hypoxia-inducible factor-1alpha in human osteosarcoma cells. European journal of pharmacology. vol 579. issue 1-3. 2008-04-15. PMID:17980359. |
furthermore, icariside ii down-regulated the levels of hif-inducible genes involved in angiogenesis, metastasis, and glucose metabolism, such as vascular endothelial growth factor (vegf), urokinase plasminogen activator receptor (upar), adrenomedullin (adm), matrix metalloproteinase 2 (mmp2), aldolase a, and enolase 1 in hos cells. |
2008-04-15 |
2023-08-12 |
human |
| Jun Wu, Jie Liu, Michael P Waalkes, Ming-Liang Cheng, Ling Li, Cheng-Xiu Li, Qing Yan. High dietary fat exacerbates arsenic-induced liver fibrosis in mice. Experimental biology and medicine (Maywood, N.J.). vol 233. issue 3. 2008-04-15. PMID:18296743. |
the expression of genes encoding matrix metalloproteinases (mmp2, mmp9) and tissue inhibitors of metalloproteinases (timp1, timp2) was also enhanced, suggestive of early oncogenic events. |
2008-04-15 |
2023-08-12 |
mouse |
| Federica Finetti, Raffaella Solito, Lucia Morbidelli, Antonio Giachetti, Marina Ziche, Sandra Donnin. Prostaglandin E2 regulates angiogenesis via activation of fibroblast growth factor receptor-1. The Journal of biological chemistry. vol 283. issue 4. 2008-03-26. PMID:18042549. |
upon binding to its receptor, pge(2) initiated an autocrine/paracrine signaling cascade involving the intracellular activation of c-src, activation of matrix metalloproteinase (predominantly mmp2), which in turn caused the mobilization of membrane-anchored fibroblast growth factor-2 (fgf-2). |
2008-03-26 |
2023-08-12 |
human |
| Severine G Dubois, Yourka D Tchoukalova, Leonie K Heilbronn, Jeanine B Albu, David E Kelley, Steven R Smith, Xiaobing Fang, Eric Ravussi. Potential role of increased matrix metalloproteinase-2 (MMP2) transcription in impaired adipogenesis in type 2 diabetes mellitus. Biochemical and biophysical research communications. vol 367. issue 4. 2008-02-29. PMID:18182154. |
potential role of increased matrix metalloproteinase-2 (mmp2) transcription in impaired adipogenesis in type 2 diabetes mellitus. |
2008-02-29 |
2023-08-12 |
human |
| Ying Chi Ip, Siu Tim Cheung, Yuk Ting Lee, Jenny C Ho, Sheung Tat Fa. Inhibition of hepatocellular carcinoma invasion by suppression of claudin-10 in HLE cells. Molecular cancer therapeutics. vol 6. issue 11. 2008-02-15. PMID:18025272. |
more importantly, matrix metalloproteinase 2 (mmp2) was up-regulated. |
2008-02-15 |
2023-08-12 |
Not clear |
| D C W Lee, D T T Chua, W I Wei, J S T Sham, A S Y La. Induction of matrix metalloproteinases by Epstein-Barr virus latent membrane protein 1 isolated from nasopharyngeal carcinoma. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 61. issue 9. 2008-02-05. PMID:17913445. |
lmp1 induces cellular proteins including cytokines and matrix metalloproteinases (e.g., mmp1, mmp2 and mmp9). |
2008-02-05 |
2023-08-12 |
human |
| Lingfei Kong, Qing Li, Lifu Wang, Zhengguo Liu, Tingyi Su. The value and correlation between PRL-3 expression and matrix metalloproteinase activity and expression in human gliomas. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 27. issue 6. 2008-01-16. PMID:18021371. |
in this study, we sought to investigate the expression of prl-3 in glioma tissues and investigate the relationship between mmps (mmp2, mmp9, membrane-type matrix metalloproteinase 1 [mt1-mmp]) activity and expression in gliomas. |
2008-01-16 |
2023-08-12 |
human |
| M C Pustovrh, A Jawerbaum, V White, E Capobianco, R Higa, N Martínez, J J López-Costa, E Gonzále. The role of nitric oxide on matrix metalloproteinase 2 (MMP2) and MMP9 in placenta and fetus from diabetic rats. Reproduction (Cambridge, England). vol 134. issue 4. 2007-12-27. PMID:17890296. |
the role of nitric oxide on matrix metalloproteinase 2 (mmp2) and mmp9 in placenta and fetus from diabetic rats. |
2007-12-27 |
2023-08-12 |
rat |
| Douglas Salmazo Rocha Morales, Norma de Oliveira Penido, Ismael Dale Coltrin Guerreiro da Silva, João Norberto Stávale, Arnaldo Guilherme, Yotaka Fukud. Matrix metalloproteinase 2: an important genetic marker for cholesteatomas. Brazilian journal of otorhinolaryngology. vol 73. issue 1. 2007-12-13. PMID:17505599. |
cholesteatoma produces enzymes that cause bone erosion like matrix metalloproteinase 2 (mmp2). |
2007-12-13 |
2023-08-12 |
Not clear |
| Christian Gorzelanny, Birgit Pöppelmann, Elwira Strozyk, Bruno M Moerschbacher, Stefan W Schneide. Specific interaction between chitosan and matrix metalloprotease 2 decreases the invasive activity of human melanoma cells. Biomacromolecules. vol 8. issue 10. 2007-12-12. PMID:17845054. |
the crucial event in metastasis is tumor invasion which in the case of melanoma cells is dependent on matrix metalloprotease 2 (mmp2). |
2007-12-12 |
2023-08-12 |
human |
| Jung Jin Hwang, Mi-Ha Park, Jae-Young Ko. Copper activates TrkB in cortical neurons in a metalloproteinase-dependent manner. Journal of neuroscience research. vol 85. issue 10. 2007-11-01. PMID:17520746. |
furthermore, cu increased the activity of matrix metalloproteinase 2 (mmp2) and mmp9 in cortical neurons. |
2007-11-01 |
2023-08-12 |
Not clear |
| Deborah Wenkert, Steven Mumm, Stefanie M Wiegand, William H McAlister, Michael P Whyt. Absence of MMP2 mutation in idiopathic multicentric osteolysis with nephropathy. Clinical orthopaedics and related research. vol 462. 2007-11-01. PMID:17563705. |
loss-of-function mutation within the gene encoding matrix metalloproteinase 2 (mmp2) causes the autosomal recessive disorder nodulosis-arthropathy-osteolysis syndrome characterized by carpal-tarsal destruction, subcutaneous nodules, and generalized osteoporosis. |
2007-11-01 |
2023-08-12 |
Not clear |
| Shun-Chieh Young, Chau-Jong Wang, Jing-Jing Lin, Pei-Ling Peng, Jui-Ling Hsu, Fen-Pi Cho. Protection effect of piper betel leaf extract against carbon tetrachloride-induced liver fibrosis in rats. Archives of toxicology. vol 81. issue 1. 2007-10-24. PMID:16676162. |
the histological examination showed the pbl extract protected liver from the damage induced by ccl(4) by decreasing alpha-smooth muscle actin (alpha-sma) expression, inducing active matrix metalloproteinase-2 (mmp2) expression though ras/erk pathway, and inhibiting timp2 level that consequently attenuated the fibrosis of liver. |
2007-10-24 |
2023-08-12 |
rat |
| P R Sudhakaran, A Radhika, S S Jaco. Monocyte macrophage differentiation in vitro: Fibronectin-dependent upregulation of certain macrophage-specific activities. Glycoconjugate journal. vol 24. issue 1. 2007-10-16. PMID:17115276. |
cells maintained on fibronectin (fn) showed significantly higher rate of endocytosis and production of mmp2 and mmp9 when compared to other matrix protein substrata. |
2007-10-16 |
2023-08-12 |
human |
| Odete Mendes, Hun-Taek Kim, Gina Lungu, George Stoic. MMP2 role in breast cancer brain metastasis development and its regulation by TIMP2 and ERK1/2. Clinical & experimental metastasis. vol 24. issue 5. 2007-10-10. PMID:17505812. |
matrix metalloproteinase 2 (mmp2) is important in breast cancer (bc) invasion and metastasis. |
2007-10-10 |
2023-08-12 |
rat |
| Kimihiko Kato, Mitsutoshi Oguri, Takeshi Hibino, Kazuhiro Yajima, Hitoshi Matsuo, Tomonori Segawa, Sachiro Watanabe, Hidemi Yoshida, Kei Satoh, Yoshinori Nozawa, Kiyoshi Yokoi, Yoshiji Yamad. Genetic factors for lone atrial fibrillation. International journal of molecular medicine. vol 19. issue 6. 2007-09-14. PMID:17487426. |
multivariable logistic regression analysis with adjustment for age, sex, body mass index, and the prevalence of smoking, hypertension, diabetes mellitus, and hyperchole-sterolemia as well as a stepwise forward selection procedure revealed that the -1306c-->t polymorphism of the matrix metalloproteinase 2 gene (mmp2) and the -592a-->c polymorphism of the interleukin 10 gene (il10) were significantly (false discovery rate of <0.05) associated with the prevalence of af. |
2007-09-14 |
2023-08-12 |
human |
| J R Salameh, Ladawn M Talbott, Warren May, Bashar Gosheh, Parminder J S Vig, D Olga McDanie. Role of biomarkers in incisional hernias. The American surgeon. vol 73. issue 6. 2007-09-13. PMID:17658092. |
western blots and reverse transcriptase-polymerase chain reaction were used to determine the ratio of type i, iii, and iv collagens, as well as matrix metalloproteinase 1 (mmp1) and mmp2 in both groups. |
2007-09-13 |
2023-08-12 |
Not clear |
| Ming-Man Zhang, Xing-Hua Gou, De-Hua Li, Lü-Nan Yan, Dong Xia, Lei Han, Zhi Su, Lai-Ying Zhao, Hai-Yang H. [Recombinant adenovirus vectors carrying antisense MMP2 inhibit invasion of HCC cells in vitro]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology. vol 13. issue 4. 2007-09-07. PMID:15850513. |
to construct a recombinant adenoviral vector carrying antisense matrix metalloproteinase-2 (mmp2) and to study its inhibitory effects on the invasiveness and migratory capacity of hepatocellular carcinoma (hcc) cell line hepg2 in vitro. |
2007-09-07 |
2023-08-12 |
Not clear |