| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Claire J Houchen, Bethany Castro, Portia Hahn Leat, Nashwa Mohammad, Faith Hall-Glenn, Erin E Buman. Treatment with an Inhibitor of Matrix Metalloproteinase 9 or Cathepsin K Lengthens Embryonic Lower Jaw Bone. Orthodontics & craniofacial research. 2023-01-21. PMID:36680416. |
our objective was to determine the effect of inhibiting osteoclast-secreted proteolytic enzymes on lower jaw bone length of avian embryos by pharmacologically inhibiting matrix metalloproteinase-9 (mmp9) or cathepsin k (ctsk). |
2023-01-21 |
2023-08-14 |
Not clear |
| Weiwei Chen, Daguang Ni, Hailin Zhang, Xia Li, Youqin Jiang, Jixiang Wu, Yan Gu, Mingcheng Gao, Woda Shi, Jianxiang Song, Wenyu Sh. Over-expression of USP15/MMP3 predict poor prognosis and promote growth, migration in non-small cell lung cancer cells. Cancer genetics. vol 272-273. 2023-01-14. PMID:36640492. |
biochemical analysis revealed that usp15 knockdown inhibited matrix metalloproteinase (mmp)3 and mmp9 expression. |
2023-01-14 |
2023-08-14 |
Not clear |
| Bowen Yang, Qiuwen Zhu, Xiaodong Wang, Jingxin Mao, Shuqing Zho. Using network pharmacology and molecular docking verification to explore the mechanism of ursolic acid in the treatment of osteoporosis. Medicine. vol 101. issue 49. 2023-01-10. PMID:36626454. |
a total of 24 core target genes were obtained, mainly including tumor protein p53 (tp53), vascular endothelial growth factor a (vegfa), interleukin-6 (il6), tumor necrosis factor (tnf), caspase3 (casp3), matrix metallo protein (mmp9), transcription factor ap-1 (jun), activator of transcription 3 (stat3), mitogen-activated protein kinase 8 (mapk8), and prostaglandin endoperoxidase 2 (ptgs2), respectively. |
2023-01-10 |
2023-08-14 |
Not clear |
| Suresh C Tyagi, Sathnur Pushpakumar, Utpal Sen, Sri Prakash L Mokshagundam, Dinesh K Kalra, Mohamed A Saad, Mahavir Sing. COVID-19 Mimics Pulmonary Dysfunction in Muscular Dystrophy as a Post-Acute Syndrome in Patients. International journal of molecular sciences. vol 24. issue 1. 2023-01-08. PMID:36613731. |
previously, we have shown the role of matrix metalloproteinase-9 (mmp9) in skeletal muscle fibrosis via a substantial increase in the levels of tumor necrosis factor-α (tnf-α) employing a dmd mouse model that was crossed-bred with mmp9-knockout (mmp9-ko or mmp9 |
2023-01-08 |
2023-08-14 |
mouse |
| Jonas Wagner, Yogesh Kumar, Anne Lautenbach, Philipp von Kroge, Stefan Wolter, Oliver Mann, Jakob Izbicki, Nicola Gagliani, Anna Dupré. Fatty acid-binding protein-4 (FABP4) and matrix metalloproteinase-9 (MMP9) as predictive values for nonalcoholic steatohepatitis (NASH). Lipids in health and disease. vol 22. issue 1. 2023-01-07. PMID:36609276. |
fatty acid-binding protein-4 (fabp4) and matrix metalloproteinase-9 (mmp9) as predictive values for nonalcoholic steatohepatitis (nash). |
2023-01-07 |
2023-08-14 |
Not clear |
| Jonas Wagner, Yogesh Kumar, Anne Lautenbach, Philipp von Kroge, Stefan Wolter, Oliver Mann, Jakob Izbicki, Nicola Gagliani, Anna Dupré. Fatty acid-binding protein-4 (FABP4) and matrix metalloproteinase-9 (MMP9) as predictive values for nonalcoholic steatohepatitis (NASH). Lipids in health and disease. vol 22. issue 1. 2023-01-07. PMID:36609276. |
the aim of this study was to test whether the serum levels of fatty acid-binding protein-4 (fabp4) and matrix metalloproteinase-9 (mmp9) could be used as a diagnostic tool for nash. |
2023-01-07 |
2023-08-14 |
Not clear |
| Cuihua Liu, Fangxin Zhao, Peng Sun, Wenjie Han, Mei Hong, Jianqiang Wu, Xuan Zhan. [miR-181c promotes the migration and angiogenesis of human A549 cells via targeting inhibition of reversion-inducing cysteine-rich protein with Kazal motifs (RECK)]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 38. issue 12. 2022-12-30. PMID:36585230. |
after transfection, the real-time quantitative pcr was used to detect the relative expressions of mir-181c and reck mrna, and western blot analysis was used to detect the expression levels of reck, matrix metalloproteinase 2 (mmp2) and mmp9 proteins. |
2022-12-30 |
2023-08-14 |
human |
| Anna Olsson-Brown, Vincent Yip, Emeka D Ogiji, Carol Jolly, Lorenzo Ressel, Anurag Sharma, Wilma Bergfeld, Xuan Liu, Nitin Khirwadkar, Teresa Bellon, Anne Dickinson, Shaheda Ahmed, Abigail Langton, Rachel Watson, Munir Pirmohamed, Daniel F Car. TNF-α mediated keratinocyte expression and release of matrix metalloproteinase 9: putative mechanism of pathogenesis in Stevens-Johnson syndrome/ toxic epidermal necrolysis. The Journal of investigative dermatology. 2022-12-29. PMID:36581093. |
epidermal matrix metalloproteinase 9 (mmp9) expression was assessed by immunohistochemistry in skin biopsies and cultured human skin explants exposed to serum from cutaneous adrs patients. |
2022-12-29 |
2023-08-14 |
human |
| Tapasi Roy, Abhishek Chatterjee, Snehasikta Swarnaka. Rotenone induced neurodegeneration is mediated via cytoskeleton degradation and necroptosis. Biochimica et biophysica acta. Molecular cell research. 2022-12-29. PMID:36581087. |
we further observed an increased expression, as well as activity of matrix metalloproteinase9 (mmp9) in rotenone exposed n2a cells; suggesting the involvement of inflammation upon rotenone exposure. |
2022-12-29 |
2023-08-14 |
Not clear |
| Martina Trentini, Ilaria Zanolla, Federica Zanotti, Elena Tiengo, Danilo Licastro, Simeone Dal Monego, Luca Lovatti, Barbara Zava. Apple Derived Exosomes Improve Collagen Type I Production and Decrease MMPs during Aging of the Skin through Downregulation of the NF-κB Pathway as Mode of Action. Cells. vol 11. issue 24. 2022-12-23. PMID:36552714. |
adnvs also reduce extracellular matrix degradation by increasing collagen synthesis (col3a1, col1a2, col8a1 and col6a1) and downregulating metalloproteinase production (mmp1, mmp8 and mmp9). |
2022-12-23 |
2023-08-14 |
Not clear |
| Dapeng Chen, Marek A Mirski, Shuo Chen, Alese P Devin, Caroline R Haddaway, Emily R Caton, Wayne A Bryden, Michael McLoughli. Human exhaled air diagnostic markers for respiratory tract infections in subjects receiving mechanical ventilation. Journal of breath research. 2022-12-21. PMID:36542858. |
the results showed that three truncated proteoforms, collagen type vi alpha three chain protein (co6a3), matrix metalloproteinase-9 (mmp9), and putative homeodomain transcription factor ii (phtf2) were independently associated with rti with the p-values of 2.0e-5, 1.1e-4, and 1.7e-3, respectively, using multiple logistic regression. |
2022-12-21 |
2023-08-14 |
human |
| Yi-Kai Wang, Shi-Jie Li, Lu-Lu Zhou, Duan Li, Li-Wei Gu. GALNT3 protects against vascular calcification by reducing oxidative stress and apoptosis of smooth muscle cells. European journal of pharmacology. vol 939. 2022-12-16. PMID:36473594. |
moreover, overexpression of galnt3 significantly down-regulated the expression of the oxidative stress markers nox2 and nox4, up-regulated total antioxidant capacity, decreased the expression of pro-inflammatory factors il-1β, tnf-α and il-8, matrix metalloproteinases mmp2 and mmp9, as well as reduced the apoptosis of cells in phosphate induced hasmcs. |
2022-12-16 |
2023-08-14 |
mouse |
| Xuli Gao, Shenyang Shen, Qiaohua Niu, Weilan Miao, Yuting Han, Ziwei Hao, Ning An, Yingyu Yang, Yu Zhang, Han Zhang, Kenneth B Storey, Hui Chan. Differential bone metabolism and protein expression in mice fed a high-fat diet versus Daurian ground squirrels following natural pre-hibernation fattening. Journal of Zhejiang University. Science. B. vol 23. issue 12. 2022-12-15. PMID:36518056. |
western blots were used to analyze protein expression levels related to bone metabolism (runt-related transcription factor 2 (runx2), osteocalcin (ocn), alkaline phosphatase (alp), osteoprotegerin (opg), receptor activator of nuclear factor-κb ligand (rankl), cathepsin k, matrix metallopeptidase 9 (mmp9), patched protein homolog 1 (ptch1), phosphorylated β-catenin (p-β-catenin), and glycogen synthase kinase-3β (gsk-3β)). |
2022-12-15 |
2023-08-14 |
mouse |
| Hongcan Huang, Jing Xie, Jieya Wei, Siqun Xu, Demao Zhang, Xuedong Zho. Fibroblast growth factor 8 (FGF8) up-regulates gelatinase expression in chondrocytes through nuclear factor-κB p65. Journal of bone and mineral metabolism. 2022-12-13. PMID:36512085. |
gelatinases, namely mmp2 and mmp9, are involved in the natural turnover of articular cartilage, as well as the loss of the cartilage matrix in osteoarthritis (oa). |
2022-12-13 |
2023-08-14 |
Not clear |
| Fan Shuyuan, Feng Xiao Yan, Li Kun, Li Bin, Diao Yunpen. Transcriptomics-based study of the protective effect of ethyl gallate on intestinal ischemia-reperfusion injury in mice. Chemistry & biodiversity. 2022-12-13. PMID:36513607. |
in iiri mouse intestinal tissue, expression of the differential protein matrix metalloproteinase 9 (mmp9), as well as its co-protein nf-κb-p65, was significantly increased, while eg inhibited the expression of mmp9 and nf-κb-p65. |
2022-12-13 |
2023-08-14 |
mouse |
| Savannah A Lynn, Flavie Soubigou, Jennifer M Dewing, Amanda Smith, Joanna Ballingall, Thea Sass, Isabela Nica, Catrin Watkins, Bhaskar Gupta, Hussein Almuhtaseb, Stephen C Lash, Ho Ming Yuen, Angela Cree, Tracey A Newman, Andrew J Lotery, J Arjuna Ratnayak. An Exploratory Study Provides Insights into MMP9 and Aβ Levels in the Vitreous and Blood across Different Ages and in a Subset of AMD Patients. International journal of molecular sciences. vol 23. issue 23. 2022-12-11. PMID:36498929. |
matrix metalloproteinase-9 (mmp9) and total amyloid-beta (aβ) are prospective biomarkers of ocular ageing and retinopathy. |
2022-12-11 |
2023-08-14 |
Not clear |
| Chunyan Chen, Ping Fan, Lirong Zhang, Kaige Xue, Jiaheng Hu, Juan Huang, Weitian Lu, Jin Xu, Shiye Xu, Guoping Qiu, Jianhua Ran, Shengwei Ga. Bumetanide Rescues Aquaporin-4 Depolarization via Suppressing β-Dystroglycan Cleavage and Provides Neuroprotection in Rat Retinal Ischemia-Reperfusion Injury. Neuroscience. 2022-12-09. PMID:36493910. |
β-dystroglycan (β-dg) is responsible for aqp4 polarization and can be cleaved by matrix metalloproteinase-9 (mmp9). |
2022-12-09 |
2023-08-14 |
rat |
| Yun-Yun Yang, Xiao-Lu Jiao, Huahui Yu, Lin-Yi Li, Juan Li, Xiao-Ping Zhang, Yan-Wen Qi. Angiopoietin-like protein 8 deficiency attenuates thoracic aortic aneurysm/dissection development in β-aminopropionitrile monofumarate-induced model mice. Biochimica et biophysica acta. Molecular basis of disease. 2022-12-09. PMID:36494038. |
in addition, the protein levels of proinflammatory cytokines and matrix metalloproteinase 9 (mmp9) and ers proteins were decreased in the aorta wall. |
2022-12-09 |
2023-08-14 |
mouse |
| Negar Noorbakhsh, Hamid Galehdari, Mohammad Shafie. The Effect of Sialic Acid on MiR-320a and Let-7e Expression in Human Glial Cell Line. Basic and clinical neuroscience. vol 13. issue 3. 2022-12-02. PMID:36457880. |
matrix metalloproteinases 9 (mmp9) is one factor that changes the exposure of different concentrations of sialic acid solution. |
2022-12-02 |
2023-08-14 |
human |
| Yongbin Jing, Mingkun Jia, Jinpeng Zhuang, Dong Han, Changlong Zhou, Jinglong Ya. TLR9 Exerts an Oncogenic Role in Promoting Osteosarcoma Progression Depending on the Regulation of NF-κB Signaling Pathway. Biological & pharmaceutical bulletin. vol 45. issue 12. 2022-11-30. PMID:36450527. |
furthermore, tlr9 overexpression could enhance the migration and invasion activities of the os cells by the upregulation of matrix metalloproteinases 2 (mmp2) and mmp9, and the opposite result was observed in tlr9-silenced cells. |
2022-11-30 |
2023-08-14 |
Not clear |